8UFY
High Resolution structure of A. viridans Lactate Oxidase
Functional Information from PROSITE/UniProt
| site_id | PS00557 |
| Number of Residues | 7 |
| Details | FMN_HYDROXY_ACID_DH_1 FMN-dependent alpha-hydroxy acid dehydrogenases active site. SNHGARQ |
| Chain | Residue | Details |
| A | SER263-GLN269 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305|PubMed:27302031 |
| Chain | Residue | Details |
| A | HIS265 | |
| B | HIS265 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17517371, ECO:0000269|PubMed:25423902, ECO:0007744|PDB:2E77, ECO:0007744|PDB:4RJE |
| Chain | Residue | Details |
| A | TYR40 | |
| B | TYR215 | |
| B | HIS265 | |
| B | ARG268 | |
| A | TYR146 | |
| A | ARG181 | |
| A | TYR215 | |
| A | HIS265 | |
| A | ARG268 | |
| B | TYR40 | |
| B | TYR146 | |
| B | ARG181 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17517371, ECO:0000269|PubMed:18367206, ECO:0007744|PDB:2DU2, ECO:0007744|PDB:2E77, ECO:0007744|PDB:2NLI |
| Chain | Residue | Details |
| A | PRO93 | |
| A | ASP296 | |
| A | ARG320 | |
| B | PRO93 | |
| B | ASP296 | |
| B | ARG320 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17517371, ECO:0000269|PubMed:18367206, ECO:0007744|PDB:2E77, ECO:0007744|PDB:2NLI |
| Chain | Residue | Details |
| A | SER122 | |
| A | THR172 | |
| A | LYS241 | |
| A | SER263 | |
| B | SER122 | |
| B | THR172 | |
| B | LYS241 | |
| B | SER263 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17517371, ECO:0007744|PDB:2E77 |
| Chain | Residue | Details |
| A | GLN144 | |
| B | GLN144 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | SITE: Is suggested to participate in control of opening/closing motions of the active-site lid in A.viridans LOX => ECO:0000305|PubMed:27302031 |
| Chain | Residue | Details |
| A | TYR215 | |
| B | TYR215 |
