8UCA

Formation of I2+III2 supercomplex rescues respiratory chain defects

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0001666	biological_process	response to hypoxia
1	0005739	cellular_component	mitochondrion
1	0005743	cellular_component	mitochondrial inner membrane
1	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
1	0009410	biological_process	response to xenobiotic stimulus
1	0016020	cellular_component	membrane
1	0016491	molecular_function	oxidoreductase activity
1	0030425	cellular_component	dendrite
1	0031966	cellular_component	mitochondrial membrane
1	0032981	biological_process	mitochondrial respiratory chain complex I assembly
1	0033194	biological_process	response to hydroperoxide
1	0043025	cellular_component	neuronal cell body
1	0045271	cellular_component	respiratory chain complex I
1	1902600	biological_process	proton transmembrane transport
1a	0001666	biological_process	response to hypoxia
1a	0005739	cellular_component	mitochondrion
1a	0005743	cellular_component	mitochondrial inner membrane
1a	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
1a	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
1a	0009410	biological_process	response to xenobiotic stimulus
1a	0016020	cellular_component	membrane
1a	0016491	molecular_function	oxidoreductase activity
1a	0030425	cellular_component	dendrite
1a	0031966	cellular_component	mitochondrial membrane
1a	0032981	biological_process	mitochondrial respiratory chain complex I assembly
1a	0033194	biological_process	response to hydroperoxide
1a	0043025	cellular_component	neuronal cell body
1a	0045271	cellular_component	respiratory chain complex I
1a	1902600	biological_process	proton transmembrane transport
2	0005739	cellular_component	mitochondrion
2	0005743	cellular_component	mitochondrial inner membrane
2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
2	0009060	biological_process	aerobic respiration
2	0016020	cellular_component	membrane
2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
2	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
2	0045271	cellular_component	respiratory chain complex I
2	0072593	biological_process	reactive oxygen species metabolic process
2	1902600	biological_process	proton transmembrane transport
2a	0005739	cellular_component	mitochondrion
2a	0005743	cellular_component	mitochondrial inner membrane
2a	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
2a	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
2a	0009060	biological_process	aerobic respiration
2a	0016020	cellular_component	membrane
2a	0032981	biological_process	mitochondrial respiratory chain complex I assembly
2a	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
2a	0045271	cellular_component	respiratory chain complex I
2a	0072593	biological_process	reactive oxygen species metabolic process
2a	1902600	biological_process	proton transmembrane transport
3	0005739	cellular_component	mitochondrion
3	0005743	cellular_component	mitochondrial inner membrane
3	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
3	0006979	biological_process	response to oxidative stress
3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
3	0009060	biological_process	aerobic respiration
3	0009642	biological_process	response to light intensity
3	0009725	biological_process	response to hormone
3	0016020	cellular_component	membrane
3	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
3	0045271	cellular_component	respiratory chain complex I
3	0071385	biological_process	cellular response to glucocorticoid stimulus
3	1902600	biological_process	proton transmembrane transport
3A	0005515	molecular_function	protein binding
3A	0005739	cellular_component	mitochondrion
3A	0005743	cellular_component	mitochondrial inner membrane
3A	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3A	0014823	biological_process	response to activity
3A	0016020	cellular_component	membrane
3A	0031625	molecular_function	ubiquitin protein ligase binding
3A	0034551	biological_process	mitochondrial respiratory chain complex III assembly
3A	0043209	cellular_component	myelin sheath
3A	0043279	biological_process	response to alkaloid
3A	0044877	molecular_function	protein-containing complex binding
3A	0045275	cellular_component	respiratory chain complex III
3A	0045333	biological_process	cellular respiration
3A	0046872	molecular_function	metal ion binding
3B	0004222	molecular_function	metalloendopeptidase activity
3B	0005515	molecular_function	protein binding
3B	0005654	cellular_component	nucleoplasm
3B	0005739	cellular_component	mitochondrion
3B	0005743	cellular_component	mitochondrial inner membrane
3B	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3B	0006508	biological_process	proteolysis
3B	0009410	biological_process	response to xenobiotic stimulus
3B	0016020	cellular_component	membrane
3B	0043209	cellular_component	myelin sheath
3B	0044877	molecular_function	protein-containing complex binding
3B	0045275	cellular_component	respiratory chain complex III
3B	0045333	biological_process	cellular respiration
3B	0046872	molecular_function	metal ion binding
3C	0001666	biological_process	response to hypoxia
3C	0005739	cellular_component	mitochondrion
3C	0005743	cellular_component	mitochondrial inner membrane
3C	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3C	0007584	biological_process	response to nutrient
3C	0008121	molecular_function	quinol-cytochrome-c reductase activity
3C	0009055	molecular_function	electron transfer activity
3C	0009410	biological_process	response to xenobiotic stimulus
3C	0009636	biological_process	response to toxic substance
3C	0009725	biological_process	response to hormone
3C	0015990	biological_process	electron transport coupled proton transport
3C	0016020	cellular_component	membrane
3C	0016491	molecular_function	oxidoreductase activity
3C	0022904	biological_process	respiratory electron transport chain
3C	0031100	biological_process	animal organ regeneration
3C	0032991	cellular_component	protein-containing complex
3C	0033590	biological_process	response to cobalamin
3C	0033762	biological_process	response to glucagon
3C	0044877	molecular_function	protein-containing complex binding
3C	0045275	cellular_component	respiratory chain complex III
3C	0045333	biological_process	cellular respiration
3C	0045471	biological_process	response to ethanol
3C	0046686	biological_process	response to cadmium ion
3C	0046688	biological_process	response to copper ion
3C	0046689	biological_process	response to mercury ion
3C	0046872	molecular_function	metal ion binding
3C	0051592	biological_process	response to calcium ion
3C	0055093	biological_process	response to hyperoxia
3C	1904421	biological_process	response to D-galactosamine
3D	0009055	molecular_function	electron transfer activity
3D	0020037	molecular_function	heme binding
3E	0008121	molecular_function	quinol-cytochrome-c reductase activity
3E	0016020	cellular_component	membrane
3E	0051537	molecular_function	2 iron, 2 sulfur cluster binding
3F	0005739	cellular_component	mitochondrion
3F	0005743	cellular_component	mitochondrial inner membrane
3F	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3F	0016020	cellular_component	membrane
3F	0044877	molecular_function	protein-containing complex binding
3F	0045275	cellular_component	respiratory chain complex III
3G	0005515	molecular_function	protein binding
3G	0005739	cellular_component	mitochondrion
3G	0005743	cellular_component	mitochondrial inner membrane
3G	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3G	0016020	cellular_component	membrane
3G	0021539	biological_process	subthalamus development
3G	0021548	biological_process	pons development
3G	0021680	biological_process	cerebellar Purkinje cell layer development
3G	0021766	biological_process	hippocampus development
3G	0021794	biological_process	thalamus development
3G	0021854	biological_process	hypothalamus development
3G	0021860	biological_process	pyramidal neuron development
3G	0030901	biological_process	midbrain development
3G	0045275	cellular_component	respiratory chain complex III
3G	0045333	biological_process	cellular respiration
3H	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3J	0005739	cellular_component	mitochondrion
3J	0005743	cellular_component	mitochondrial inner membrane
3J	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3J	0016020	cellular_component	membrane
3J	0045275	cellular_component	respiratory chain complex III
3J	0045333	biological_process	cellular respiration
3K	0005739	cellular_component	mitochondrion
3K	0005743	cellular_component	mitochondrial inner membrane
3K	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3K	0016020	cellular_component	membrane
3K	0045275	cellular_component	respiratory chain complex III
3K	0045333	biological_process	cellular respiration
3L	0005515	molecular_function	protein binding
3L	0005739	cellular_component	mitochondrion
3L	0005743	cellular_component	mitochondrial inner membrane
3L	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3L	0014823	biological_process	response to activity
3L	0016020	cellular_component	membrane
3L	0031625	molecular_function	ubiquitin protein ligase binding
3L	0034551	biological_process	mitochondrial respiratory chain complex III assembly
3L	0043209	cellular_component	myelin sheath
3L	0043279	biological_process	response to alkaloid
3L	0044877	molecular_function	protein-containing complex binding
3L	0045275	cellular_component	respiratory chain complex III
3L	0045333	biological_process	cellular respiration
3L	0046872	molecular_function	metal ion binding
3M	0004222	molecular_function	metalloendopeptidase activity
3M	0005515	molecular_function	protein binding
3M	0005654	cellular_component	nucleoplasm
3M	0005739	cellular_component	mitochondrion
3M	0005743	cellular_component	mitochondrial inner membrane
3M	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3M	0006508	biological_process	proteolysis
3M	0009410	biological_process	response to xenobiotic stimulus
3M	0016020	cellular_component	membrane
3M	0043209	cellular_component	myelin sheath
3M	0044877	molecular_function	protein-containing complex binding
3M	0045275	cellular_component	respiratory chain complex III
3M	0045333	biological_process	cellular respiration
3M	0046872	molecular_function	metal ion binding
3N	0001666	biological_process	response to hypoxia
3N	0005739	cellular_component	mitochondrion
3N	0005743	cellular_component	mitochondrial inner membrane
3N	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3N	0007584	biological_process	response to nutrient
3N	0008121	molecular_function	quinol-cytochrome-c reductase activity
3N	0009055	molecular_function	electron transfer activity
3N	0009410	biological_process	response to xenobiotic stimulus
3N	0009636	biological_process	response to toxic substance
3N	0009725	biological_process	response to hormone
3N	0015990	biological_process	electron transport coupled proton transport
3N	0016020	cellular_component	membrane
3N	0016491	molecular_function	oxidoreductase activity
3N	0022904	biological_process	respiratory electron transport chain
3N	0031100	biological_process	animal organ regeneration
3N	0032991	cellular_component	protein-containing complex
3N	0033590	biological_process	response to cobalamin
3N	0033762	biological_process	response to glucagon
3N	0044877	molecular_function	protein-containing complex binding
3N	0045275	cellular_component	respiratory chain complex III
3N	0045333	biological_process	cellular respiration
3N	0045471	biological_process	response to ethanol
3N	0046686	biological_process	response to cadmium ion
3N	0046688	biological_process	response to copper ion
3N	0046689	biological_process	response to mercury ion
3N	0046872	molecular_function	metal ion binding
3N	0051592	biological_process	response to calcium ion
3N	0055093	biological_process	response to hyperoxia
3N	1904421	biological_process	response to D-galactosamine
3O	0009055	molecular_function	electron transfer activity
3O	0020037	molecular_function	heme binding
3P	0008121	molecular_function	quinol-cytochrome-c reductase activity
3P	0016020	cellular_component	membrane
3P	0051537	molecular_function	2 iron, 2 sulfur cluster binding
3Q	0005739	cellular_component	mitochondrion
3Q	0005743	cellular_component	mitochondrial inner membrane
3Q	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3Q	0016020	cellular_component	membrane
3Q	0044877	molecular_function	protein-containing complex binding
3Q	0045275	cellular_component	respiratory chain complex III
3R	0005515	molecular_function	protein binding
3R	0005739	cellular_component	mitochondrion
3R	0005743	cellular_component	mitochondrial inner membrane
3R	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3R	0016020	cellular_component	membrane
3R	0021539	biological_process	subthalamus development
3R	0021548	biological_process	pons development
3R	0021680	biological_process	cerebellar Purkinje cell layer development
3R	0021766	biological_process	hippocampus development
3R	0021794	biological_process	thalamus development
3R	0021854	biological_process	hypothalamus development
3R	0021860	biological_process	pyramidal neuron development
3R	0030901	biological_process	midbrain development
3R	0045275	cellular_component	respiratory chain complex III
3R	0045333	biological_process	cellular respiration
3S	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3T	0008121	molecular_function	quinol-cytochrome-c reductase activity
3U	0005739	cellular_component	mitochondrion
3U	0005743	cellular_component	mitochondrial inner membrane
3U	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3U	0016020	cellular_component	membrane
3U	0045275	cellular_component	respiratory chain complex III
3U	0045333	biological_process	cellular respiration
3V	0005739	cellular_component	mitochondrion
3V	0005743	cellular_component	mitochondrial inner membrane
3V	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
3V	0016020	cellular_component	membrane
3V	0045275	cellular_component	respiratory chain complex III
3V	0045333	biological_process	cellular respiration
3a	0005739	cellular_component	mitochondrion
3a	0005743	cellular_component	mitochondrial inner membrane
3a	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
3a	0006979	biological_process	response to oxidative stress
3a	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
3a	0009060	biological_process	aerobic respiration
3a	0009642	biological_process	response to light intensity
3a	0009725	biological_process	response to hormone
3a	0016020	cellular_component	membrane
3a	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
3a	0045271	cellular_component	respiratory chain complex I
3a	0071385	biological_process	cellular response to glucocorticoid stimulus
3a	1902600	biological_process	proton transmembrane transport
4	0001666	biological_process	response to hypoxia
4	0001701	biological_process	in utero embryonic development
4	0003954	molecular_function	NADH dehydrogenase activity
4	0005739	cellular_component	mitochondrion
4	0005743	cellular_component	mitochondrial inner membrane
4	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
4	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
4	0009060	biological_process	aerobic respiration
4	0015990	biological_process	electron transport coupled proton transport
4	0016020	cellular_component	membrane
4	0021549	biological_process	cerebellum development
4	0032981	biological_process	mitochondrial respiratory chain complex I assembly
4	0035094	biological_process	response to nicotine
4	0042773	biological_process	ATP synthesis coupled electron transport
4	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
4	0045271	cellular_component	respiratory chain complex I
4	0045471	biological_process	response to ethanol
4	0048039	molecular_function	ubiquinone binding
4L	0005739	cellular_component	mitochondrion
4L	0005743	cellular_component	mitochondrial inner membrane
4L	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
4L	0009060	biological_process	aerobic respiration
4L	0016020	cellular_component	membrane
4L	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
4L	0042773	biological_process	ATP synthesis coupled electron transport
4L	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
4L	0045271	cellular_component	respiratory chain complex I
4L	1902600	biological_process	proton transmembrane transport
4a	0001666	biological_process	response to hypoxia
4a	0001701	biological_process	in utero embryonic development
4a	0003954	molecular_function	NADH dehydrogenase activity
4a	0005739	cellular_component	mitochondrion
4a	0005743	cellular_component	mitochondrial inner membrane
4a	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
4a	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
4a	0009060	biological_process	aerobic respiration
4a	0015990	biological_process	electron transport coupled proton transport
4a	0016020	cellular_component	membrane
4a	0021549	biological_process	cerebellum development
4a	0032981	biological_process	mitochondrial respiratory chain complex I assembly
4a	0035094	biological_process	response to nicotine
4a	0042773	biological_process	ATP synthesis coupled electron transport
4a	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
4a	0045271	cellular_component	respiratory chain complex I
4a	0045471	biological_process	response to ethanol
4a	0048039	molecular_function	ubiquinone binding
4l	0005739	cellular_component	mitochondrion
4l	0005743	cellular_component	mitochondrial inner membrane
4l	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
4l	0009060	biological_process	aerobic respiration
4l	0016020	cellular_component	membrane
4l	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
4l	0042773	biological_process	ATP synthesis coupled electron transport
4l	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
4l	0045271	cellular_component	respiratory chain complex I
4l	1902600	biological_process	proton transmembrane transport
5	0005739	cellular_component	mitochondrion
5	0005743	cellular_component	mitochondrial inner membrane
5	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
5	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
5	0009060	biological_process	aerobic respiration
5	0015990	biological_process	electron transport coupled proton transport
5	0016020	cellular_component	membrane
5	0032981	biological_process	mitochondrial respiratory chain complex I assembly
5	0042773	biological_process	ATP synthesis coupled electron transport
5	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
5	0045271	cellular_component	respiratory chain complex I
5a	0005739	cellular_component	mitochondrion
5a	0005743	cellular_component	mitochondrial inner membrane
5a	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
5a	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
5a	0009060	biological_process	aerobic respiration
5a	0015990	biological_process	electron transport coupled proton transport
5a	0016020	cellular_component	membrane
5a	0032981	biological_process	mitochondrial respiratory chain complex I assembly
5a	0042773	biological_process	ATP synthesis coupled electron transport
5a	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
5a	0045271	cellular_component	respiratory chain complex I
6	0005739	cellular_component	mitochondrion
6	0005743	cellular_component	mitochondrial inner membrane
6	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
6	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
6	0009060	biological_process	aerobic respiration
6	0016020	cellular_component	membrane
6	0032981	biological_process	mitochondrial respiratory chain complex I assembly
6	0035094	biological_process	response to nicotine
6	0042220	biological_process	response to cocaine
6	0042542	biological_process	response to hydrogen peroxide
6	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
6	0045271	cellular_component	respiratory chain complex I
6	1902600	biological_process	proton transmembrane transport
6a	0005739	cellular_component	mitochondrion
6a	0005743	cellular_component	mitochondrial inner membrane
6a	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
6a	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
6a	0009060	biological_process	aerobic respiration
6a	0016020	cellular_component	membrane
6a	0032981	biological_process	mitochondrial respiratory chain complex I assembly
6a	0035094	biological_process	response to nicotine
6a	0042220	biological_process	response to cocaine
6a	0042542	biological_process	response to hydrogen peroxide
6a	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
6a	0045271	cellular_component	respiratory chain complex I
6a	1902600	biological_process	proton transmembrane transport
A1	0005739	cellular_component	mitochondrion
A1	0005743	cellular_component	mitochondrial inner membrane
A1	0009060	biological_process	aerobic respiration
A1	0016020	cellular_component	membrane
A1	0031966	cellular_component	mitochondrial membrane
A1	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
A1	0045271	cellular_component	respiratory chain complex I
A2	0001835	biological_process	blastocyst hatching
A2	0005739	cellular_component	mitochondrion
A2	0005743	cellular_component	mitochondrial inner membrane
A2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A2	0009060	biological_process	aerobic respiration
A2	0016020	cellular_component	membrane
A2	0031966	cellular_component	mitochondrial membrane
A2	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
A2	0045271	cellular_component	respiratory chain complex I
A2	1902600	biological_process	proton transmembrane transport
A3	0003674	molecular_function	molecular_function
A3	0005739	cellular_component	mitochondrion
A3	0005743	cellular_component	mitochondrial inner membrane
A3	0009060	biological_process	aerobic respiration
A3	0016020	cellular_component	membrane
A3	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
A3	0045271	cellular_component	respiratory chain complex I
A5	0005739	cellular_component	mitochondrion
A5	0005743	cellular_component	mitochondrial inner membrane
A5	0009060	biological_process	aerobic respiration
A5	0016020	cellular_component	membrane
A5	0022904	biological_process	respiratory electron transport chain
A5	0032991	cellular_component	protein-containing complex
A5	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
A5	0045271	cellular_component	respiratory chain complex I
A6	0003674	molecular_function	molecular_function
A6	0005739	cellular_component	mitochondrion
A6	0005743	cellular_component	mitochondrial inner membrane
A6	0009060	biological_process	aerobic respiration
A6	0016020	cellular_component	membrane
A6	0031966	cellular_component	mitochondrial membrane
A6	0032981	biological_process	mitochondrial respiratory chain complex I assembly
A6	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
A6	0045271	cellular_component	respiratory chain complex I
A7	0005739	cellular_component	mitochondrion
A7	0005743	cellular_component	mitochondrial inner membrane
A7	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
A7	0009060	biological_process	aerobic respiration
A7	0016020	cellular_component	membrane
A7	0042773	biological_process	ATP synthesis coupled electron transport
A7	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
A7	0045271	cellular_component	respiratory chain complex I
A8	0005739	cellular_component	mitochondrion
A8	0005743	cellular_component	mitochondrial inner membrane
A8	0005758	cellular_component	mitochondrial intermembrane space
A8	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
A8	0009060	biological_process	aerobic respiration
A8	0016020	cellular_component	membrane
A8	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
A8	0044877	molecular_function	protein-containing complex binding
A8	0045271	cellular_component	respiratory chain complex I
A9	0003954	molecular_function	NADH dehydrogenase activity
A9	0005515	molecular_function	protein binding
A9	0005739	cellular_component	mitochondrion
A9	0005743	cellular_component	mitochondrial inner membrane
A9	0005759	cellular_component	mitochondrial matrix
A9	0006744	biological_process	ubiquinone biosynthetic process
A9	0007623	biological_process	circadian rhythm
A9	0009060	biological_process	aerobic respiration
A9	0031966	cellular_component	mitochondrial membrane
A9	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
A9	0044877	molecular_function	protein-containing complex binding
A9	0045271	cellular_component	respiratory chain complex I
AB	0000035	molecular_function	acyl binding
AB	0000036	molecular_function	acyl carrier activity
AB	0005198	molecular_function	structural molecule activity
AB	0005654	cellular_component	nucleoplasm
AB	0005739	cellular_component	mitochondrion
AB	0005743	cellular_component	mitochondrial inner membrane
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AB	0009060	biological_process	aerobic respiration
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AB	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
AB	0044571	biological_process	[2Fe-2S] cluster assembly
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AB	0099128	cellular_component	mitochondrial [2Fe-2S] assembly complex
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AB	1990229	cellular_component	iron-sulfur cluster assembly complex
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AC	0000036	molecular_function	acyl carrier activity
AC	0005198	molecular_function	structural molecule activity
AC	0005654	cellular_component	nucleoplasm
AC	0005739	cellular_component	mitochondrion
AC	0005743	cellular_component	mitochondrial inner membrane
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AC	0006631	biological_process	fatty acid metabolic process
AC	0006633	biological_process	fatty acid biosynthetic process
AC	0009060	biological_process	aerobic respiration
AC	0016226	biological_process	iron-sulfur cluster assembly
AC	0031966	cellular_component	mitochondrial membrane
AC	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
AC	0044571	biological_process	[2Fe-2S] cluster assembly
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AC	0099128	cellular_component	mitochondrial [2Fe-2S] assembly complex
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AC	1990229	cellular_component	iron-sulfur cluster assembly complex
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AL	0005739	cellular_component	mitochondrion
AL	0005743	cellular_component	mitochondrial inner membrane
AL	0005759	cellular_component	mitochondrial matrix
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AL	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
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AL	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
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AL	0045271	cellular_component	respiratory chain complex I
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AM	0005743	cellular_component	mitochondrial inner membrane
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AN	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
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AO	0005654	cellular_component	nucleoplasm
AO	0005737	cellular_component	cytoplasm
AO	0005739	cellular_component	mitochondrion
AO	0005743	cellular_component	mitochondrial inner membrane
AO	0006915	biological_process	apoptotic process
AO	0009060	biological_process	aerobic respiration
AO	0016020	cellular_component	membrane
AO	0031966	cellular_component	mitochondrial membrane
AO	0032981	biological_process	mitochondrial respiratory chain complex I assembly
AO	0035458	biological_process	cellular response to interferon-beta
AO	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
AO	0045039	biological_process	protein insertion into mitochondrial inner membrane
AO	0045271	cellular_component	respiratory chain complex I
AO	0045732	biological_process	positive regulation of protein catabolic process
AO	0045892	biological_process	negative regulation of DNA-templated transcription
AO	0071300	biological_process	cellular response to retinoic acid
AO	0097191	biological_process	extrinsic apoptotic signaling pathway
AO	0098803	cellular_component	respiratory chain complex
AO	1900119	biological_process	positive regulation of execution phase of apoptosis
B1	0005739	cellular_component	mitochondrion
B1	0005743	cellular_component	mitochondrial inner membrane
B1	0009060	biological_process	aerobic respiration
B1	0016020	cellular_component	membrane
B1	0016607	cellular_component	nuclear speck
B1	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
B1	0045271	cellular_component	respiratory chain complex I
B2	0003674	molecular_function	molecular_function
B2	0005739	cellular_component	mitochondrion
B2	0005743	cellular_component	mitochondrial inner membrane
B2	0009060	biological_process	aerobic respiration
B2	0016020	cellular_component	membrane
B2	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
B2	0045271	cellular_component	respiratory chain complex I
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B3	0005743	cellular_component	mitochondrial inner membrane
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B3	0016020	cellular_component	membrane
B3	0022900	biological_process	electron transport chain
B3	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
B3	0045271	cellular_component	respiratory chain complex I
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B4	0005654	cellular_component	nucleoplasm
B4	0005739	cellular_component	mitochondrion
B4	0005743	cellular_component	mitochondrial inner membrane
B4	0009060	biological_process	aerobic respiration
B4	0016020	cellular_component	membrane
B4	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
B4	0045271	cellular_component	respiratory chain complex I
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B5	0005654	cellular_component	nucleoplasm
B5	0005739	cellular_component	mitochondrion
B5	0005743	cellular_component	mitochondrial inner membrane
B5	0009060	biological_process	aerobic respiration
B5	0016020	cellular_component	membrane
B5	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
B5	0045271	cellular_component	respiratory chain complex I
B6	0005654	cellular_component	nucleoplasm
B6	0005739	cellular_component	mitochondrion
B6	0005743	cellular_component	mitochondrial inner membrane
B6	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
B6	0009060	biological_process	aerobic respiration
B6	0016020	cellular_component	membrane
B6	0031966	cellular_component	mitochondrial membrane
B6	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
B6	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
B6	0045271	cellular_component	respiratory chain complex I
B7	0003674	molecular_function	molecular_function
B7	0005739	cellular_component	mitochondrion
B7	0005743	cellular_component	mitochondrial inner membrane
B7	0005758	cellular_component	mitochondrial intermembrane space
B7	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B7	0009060	biological_process	aerobic respiration
B7	0016020	cellular_component	membrane
B7	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
B7	0045271	cellular_component	respiratory chain complex I
B7	1902600	biological_process	proton transmembrane transport
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B8	0005739	cellular_component	mitochondrion
B8	0005743	cellular_component	mitochondrial inner membrane
B8	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
B8	0009060	biological_process	aerobic respiration
B8	0016020	cellular_component	membrane
B8	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
B8	0045271	cellular_component	respiratory chain complex I
B9	0005739	cellular_component	mitochondrion
B9	0005743	cellular_component	mitochondrial inner membrane
B9	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
B9	0009060	biological_process	aerobic respiration
B9	0016020	cellular_component	membrane
B9	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
B9	0045271	cellular_component	respiratory chain complex I
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BL	0005743	cellular_component	mitochondrial inner membrane
BL	0009060	biological_process	aerobic respiration
BL	0016020	cellular_component	membrane
BL	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
BL	0045271	cellular_component	respiratory chain complex I
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BM	0005739	cellular_component	mitochondrion
BM	0005743	cellular_component	mitochondrial inner membrane
BM	0009060	biological_process	aerobic respiration
BM	0016020	cellular_component	membrane
BM	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
BM	0045271	cellular_component	respiratory chain complex I
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C1	0005739	cellular_component	mitochondrion
C1	0005743	cellular_component	mitochondrial inner membrane
C1	0009060	biological_process	aerobic respiration
C1	0016020	cellular_component	membrane
C1	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
C1	0045271	cellular_component	respiratory chain complex I
C2	0005737	cellular_component	cytoplasm
C2	0005739	cellular_component	mitochondrion
C2	0005743	cellular_component	mitochondrial inner membrane
C2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
C2	0009060	biological_process	aerobic respiration
C2	0010918	biological_process	positive regulation of mitochondrial membrane potential
C2	0016020	cellular_component	membrane
C2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
C2	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
C2	0045271	cellular_component	respiratory chain complex I
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C2	1903427	biological_process	negative regulation of reactive oxygen species biosynthetic process
C2	2001171	biological_process	positive regulation of ATP biosynthetic process
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S1	0005739	cellular_component	mitochondrion
S1	0005743	cellular_component	mitochondrial inner membrane
S1	0005758	cellular_component	mitochondrial intermembrane space
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S1	0009055	molecular_function	electron transfer activity
S1	0009060	biological_process	aerobic respiration
S1	0016020	cellular_component	membrane
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S1	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S1	0032981	biological_process	mitochondrial respiratory chain complex I assembly
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S1	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
S1	0043209	cellular_component	myelin sheath
S1	0045271	cellular_component	respiratory chain complex I
S1	0045333	biological_process	cellular respiration
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S1	0051536	molecular_function	iron-sulfur cluster binding
S1	0051537	molecular_function	2 iron, 2 sulfur cluster binding
S1	0051539	molecular_function	4 iron, 4 sulfur cluster binding
S1	1902600	biological_process	proton transmembrane transport
S2	0003954	molecular_function	NADH dehydrogenase activity
S2	0005515	molecular_function	protein binding
S2	0005739	cellular_component	mitochondrion
S2	0005743	cellular_component	mitochondrial inner membrane
S2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S2	0009060	biological_process	aerobic respiration
S2	0016020	cellular_component	membrane
S2	0016491	molecular_function	oxidoreductase activity
S2	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S2	0019826	molecular_function	oxygen sensor activity
S2	0022008	biological_process	neurogenesis
S2	0031625	molecular_function	ubiquitin protein ligase binding
S2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
S2	0042063	biological_process	gliogenesis
S2	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
S2	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
S2	0045271	cellular_component	respiratory chain complex I
S2	0046872	molecular_function	metal ion binding
S2	0048038	molecular_function	quinone binding
S2	0051287	molecular_function	NAD binding
S2	0051536	molecular_function	iron-sulfur cluster binding
S2	0051539	molecular_function	4 iron, 4 sulfur cluster binding
S2	0061351	biological_process	neural precursor cell proliferation
S2	0071453	biological_process	cellular response to oxygen levels
S2	1902600	biological_process	proton transmembrane transport
S3	0003954	molecular_function	NADH dehydrogenase activity
S3	0005515	molecular_function	protein binding
S3	0005739	cellular_component	mitochondrion
S3	0005743	cellular_component	mitochondrial inner membrane
S3	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S3	0009060	biological_process	aerobic respiration
S3	0016020	cellular_component	membrane
S3	0016491	molecular_function	oxidoreductase activity
S3	0016604	cellular_component	nuclear body
S3	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S3	0031966	cellular_component	mitochondrial membrane
S3	0032981	biological_process	mitochondrial respiratory chain complex I assembly
S3	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
S3	0043209	cellular_component	myelin sheath
S3	0045271	cellular_component	respiratory chain complex I
S3	0072593	biological_process	reactive oxygen species metabolic process
S3	1902600	biological_process	proton transmembrane transport
S4	0003016	biological_process	respiratory system process
S4	0005739	cellular_component	mitochondrion
S4	0005743	cellular_component	mitochondrial inner membrane
S4	0006099	biological_process	tricarboxylic acid cycle
S4	0006954	biological_process	inflammatory response
S4	0007420	biological_process	brain development
S4	0007601	biological_process	visual perception
S4	0007605	biological_process	sensory perception of sound
S4	0007628	biological_process	adult walking behavior
S4	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S4	0009060	biological_process	aerobic respiration
S4	0014876	biological_process	response to injury involved in regulation of muscle adaptation
S4	0016020	cellular_component	membrane
S4	0022900	biological_process	electron transport chain
S4	0022904	biological_process	respiratory electron transport chain
S4	0030534	biological_process	adult behavior
S4	0032981	biological_process	mitochondrial respiratory chain complex I assembly
S4	0036343	biological_process	psychomotor behavior
S4	0042417	biological_process	dopamine metabolic process
S4	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
S4	0045087	biological_process	innate immune response
S4	0045271	cellular_component	respiratory chain complex I
S4	0048666	biological_process	neuron development
S4	0050890	biological_process	cognition
S4	0051402	biological_process	neuron apoptotic process
S4	0051881	biological_process	regulation of mitochondrial membrane potential
S4	0071453	biological_process	cellular response to oxygen levels
S4	0072593	biological_process	reactive oxygen species metabolic process
S4	1902600	biological_process	proton transmembrane transport
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S5	0005739	cellular_component	mitochondrion
S5	0005743	cellular_component	mitochondrial inner membrane
S5	0005758	cellular_component	mitochondrial intermembrane space
S5	0009060	biological_process	aerobic respiration
S5	0016020	cellular_component	membrane
S5	0032981	biological_process	mitochondrial respiratory chain complex I assembly
S5	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
S5	0045271	cellular_component	respiratory chain complex I
S6	0001822	biological_process	kidney development
S6	0003674	molecular_function	molecular_function
S6	0005739	cellular_component	mitochondrion
S6	0005743	cellular_component	mitochondrial inner membrane
S6	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S6	0006631	biological_process	fatty acid metabolic process
S6	0006936	biological_process	muscle contraction
S6	0007005	biological_process	mitochondrion organization
S6	0009060	biological_process	aerobic respiration
S6	0010467	biological_process	gene expression
S6	0016020	cellular_component	membrane
S6	0017145	biological_process	stem cell division
S6	0022904	biological_process	respiratory electron transport chain
S6	0030330	biological_process	DNA damage response, signal transduction by p53 class mediator
S6	0032981	biological_process	mitochondrial respiratory chain complex I assembly
S6	0035264	biological_process	multicellular organism growth
S6	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
S6	0045271	cellular_component	respiratory chain complex I
S6	0051881	biological_process	regulation of mitochondrial membrane potential
S6	0061458	biological_process	reproductive system development
S6	0072359	biological_process	circulatory system development
S6	0072497	biological_process	mesenchymal stem cell differentiation
S6	0072593	biological_process	reactive oxygen species metabolic process
S6	0090398	biological_process	cellular senescence
S6	0097168	biological_process	mesenchymal stem cell proliferation
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S7	0004497	molecular_function	monooxygenase activity
S7	0005739	cellular_component	mitochondrion
S7	0005743	cellular_component	mitochondrial inner membrane
S7	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S7	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S7	0009060	biological_process	aerobic respiration
S7	0015990	biological_process	electron transport coupled proton transport
S7	0016020	cellular_component	membrane
S7	0016491	molecular_function	oxidoreductase activity
S7	0032981	biological_process	mitochondrial respiratory chain complex I assembly
S7	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
S7	0045271	cellular_component	respiratory chain complex I
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S7	0048038	molecular_function	quinone binding
S7	0051536	molecular_function	iron-sulfur cluster binding
S7	0051539	molecular_function	4 iron, 4 sulfur cluster binding
S8	0003954	molecular_function	NADH dehydrogenase activity
S8	0005515	molecular_function	protein binding
S8	0005739	cellular_component	mitochondrion
S8	0005743	cellular_component	mitochondrial inner membrane
S8	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S8	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S8	0009060	biological_process	aerobic respiration
S8	0016020	cellular_component	membrane
S8	0016491	molecular_function	oxidoreductase activity
S8	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S8	0032981	biological_process	mitochondrial respiratory chain complex I assembly
S8	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
S8	0045271	cellular_component	respiratory chain complex I
S8	0046872	molecular_function	metal ion binding
S8	0051536	molecular_function	iron-sulfur cluster binding
S8	0051539	molecular_function	4 iron, 4 sulfur cluster binding
S8	1902600	biological_process	proton transmembrane transport
V1	0005515	molecular_function	protein binding
V1	0005739	cellular_component	mitochondrion
V1	0005743	cellular_component	mitochondrial inner membrane
V1	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
V1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
V1	0009060	biological_process	aerobic respiration
V1	0010181	molecular_function	FMN binding
V1	0016020	cellular_component	membrane
V1	0016491	molecular_function	oxidoreductase activity
V1	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
V1	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
V1	0045271	cellular_component	respiratory chain complex I
V1	0046872	molecular_function	metal ion binding
V1	0051287	molecular_function	NAD binding
V1	0051536	molecular_function	iron-sulfur cluster binding
V1	0051539	molecular_function	4 iron, 4 sulfur cluster binding
V1	1902600	biological_process	proton transmembrane transport
V2	0003954	molecular_function	NADH dehydrogenase activity
V2	0005739	cellular_component	mitochondrion
V2	0005743	cellular_component	mitochondrial inner membrane
V2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
V2	0007399	biological_process	nervous system development
V2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
V2	0009060	biological_process	aerobic respiration
V2	0016020	cellular_component	membrane
V2	0016491	molecular_function	oxidoreductase activity
V2	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
V2	0043209	cellular_component	myelin sheath
V2	0045271	cellular_component	respiratory chain complex I
V2	0046872	molecular_function	metal ion binding
V2	0048738	biological_process	cardiac muscle tissue development
V2	0051536	molecular_function	iron-sulfur cluster binding
V2	0051537	molecular_function	2 iron, 2 sulfur cluster binding
V2	1902600	biological_process	proton transmembrane transport
V3	0005739	cellular_component	mitochondrion
V3	0005743	cellular_component	mitochondrial inner membrane
V3	0009060	biological_process	aerobic respiration
V3	0016020	cellular_component	membrane
V3	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
V3	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
V3	0045271	cellular_component	respiratory chain complex I
a1	0005739	cellular_component	mitochondrion
a1	0005743	cellular_component	mitochondrial inner membrane
a1	0009060	biological_process	aerobic respiration
a1	0016020	cellular_component	membrane
a1	0031966	cellular_component	mitochondrial membrane
a1	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
a1	0045271	cellular_component	respiratory chain complex I
a2	0001835	biological_process	blastocyst hatching
a2	0005739	cellular_component	mitochondrion
a2	0005743	cellular_component	mitochondrial inner membrane
a2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
a2	0009060	biological_process	aerobic respiration
a2	0016020	cellular_component	membrane
a2	0031966	cellular_component	mitochondrial membrane
a2	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
a2	0045271	cellular_component	respiratory chain complex I
a2	1902600	biological_process	proton transmembrane transport
a3	0003674	molecular_function	molecular_function
a3	0005739	cellular_component	mitochondrion
a3	0005743	cellular_component	mitochondrial inner membrane
a3	0009060	biological_process	aerobic respiration
a3	0016020	cellular_component	membrane
a3	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
a3	0045271	cellular_component	respiratory chain complex I
a5	0005739	cellular_component	mitochondrion
a5	0005743	cellular_component	mitochondrial inner membrane
a5	0009060	biological_process	aerobic respiration
a5	0016020	cellular_component	membrane
a5	0022904	biological_process	respiratory electron transport chain
a5	0032991	cellular_component	protein-containing complex
a5	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
a5	0045271	cellular_component	respiratory chain complex I
a6	0003674	molecular_function	molecular_function
a6	0005739	cellular_component	mitochondrion
a6	0005743	cellular_component	mitochondrial inner membrane
a6	0009060	biological_process	aerobic respiration
a6	0016020	cellular_component	membrane
a6	0031966	cellular_component	mitochondrial membrane
a6	0032981	biological_process	mitochondrial respiratory chain complex I assembly
a6	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
a6	0045271	cellular_component	respiratory chain complex I
a7	0005739	cellular_component	mitochondrion
a7	0005743	cellular_component	mitochondrial inner membrane
a7	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
a7	0009060	biological_process	aerobic respiration
a7	0016020	cellular_component	membrane
a7	0042773	biological_process	ATP synthesis coupled electron transport
a7	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
a7	0045271	cellular_component	respiratory chain complex I
a8	0005739	cellular_component	mitochondrion
a8	0005743	cellular_component	mitochondrial inner membrane
a8	0005758	cellular_component	mitochondrial intermembrane space
a8	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
a8	0009060	biological_process	aerobic respiration
a8	0016020	cellular_component	membrane
a8	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
a8	0044877	molecular_function	protein-containing complex binding
a8	0045271	cellular_component	respiratory chain complex I
a9	0003954	molecular_function	NADH dehydrogenase activity
a9	0005515	molecular_function	protein binding
a9	0005739	cellular_component	mitochondrion
a9	0005743	cellular_component	mitochondrial inner membrane
a9	0005759	cellular_component	mitochondrial matrix
a9	0006744	biological_process	ubiquinone biosynthetic process
a9	0007623	biological_process	circadian rhythm
a9	0009060	biological_process	aerobic respiration
a9	0031966	cellular_component	mitochondrial membrane
a9	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
a9	0044877	molecular_function	protein-containing complex binding
a9	0045271	cellular_component	respiratory chain complex I
ab	0000035	molecular_function	acyl binding
ab	0000036	molecular_function	acyl carrier activity
ab	0005198	molecular_function	structural molecule activity
ab	0005654	cellular_component	nucleoplasm
ab	0005739	cellular_component	mitochondrion
ab	0005743	cellular_component	mitochondrial inner membrane
ab	0006629	biological_process	lipid metabolic process
ab	0006631	biological_process	fatty acid metabolic process
ab	0006633	biological_process	fatty acid biosynthetic process
ab	0009060	biological_process	aerobic respiration
ab	0016226	biological_process	iron-sulfur cluster assembly
ab	0031966	cellular_component	mitochondrial membrane
ab	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
ab	0044571	biological_process	[2Fe-2S] cluster assembly
ab	0045271	cellular_component	respiratory chain complex I
ab	0099128	cellular_component	mitochondrial [2Fe-2S] assembly complex
ab	0140978	molecular_function	mitochondrial large ribosomal subunit binding
ab	1990229	cellular_component	iron-sulfur cluster assembly complex
ac	0000035	molecular_function	acyl binding
ac	0000036	molecular_function	acyl carrier activity
ac	0005198	molecular_function	structural molecule activity
ac	0005654	cellular_component	nucleoplasm
ac	0005739	cellular_component	mitochondrion
ac	0005743	cellular_component	mitochondrial inner membrane
ac	0006629	biological_process	lipid metabolic process
ac	0006631	biological_process	fatty acid metabolic process
ac	0006633	biological_process	fatty acid biosynthetic process
ac	0009060	biological_process	aerobic respiration
ac	0016226	biological_process	iron-sulfur cluster assembly
ac	0031966	cellular_component	mitochondrial membrane
ac	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
ac	0044571	biological_process	[2Fe-2S] cluster assembly
ac	0045271	cellular_component	respiratory chain complex I
ac	0099128	cellular_component	mitochondrial [2Fe-2S] assembly complex
ac	0140978	molecular_function	mitochondrial large ribosomal subunit binding
ac	1990229	cellular_component	iron-sulfur cluster assembly complex
al	0005737	cellular_component	cytoplasm
al	0005739	cellular_component	mitochondrion
al	0005743	cellular_component	mitochondrial inner membrane
al	0005759	cellular_component	mitochondrial matrix
al	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
al	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
al	0009060	biological_process	aerobic respiration
al	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
al	0043209	cellular_component	myelin sheath
al	0045271	cellular_component	respiratory chain complex I
al	1902600	biological_process	proton transmembrane transport
am	0005739	cellular_component	mitochondrion
am	0005743	cellular_component	mitochondrial inner membrane
am	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
am	0016020	cellular_component	membrane
am	0045271	cellular_component	respiratory chain complex I
an	0003674	molecular_function	molecular_function
an	0005739	cellular_component	mitochondrion
an	0005743	cellular_component	mitochondrial inner membrane
an	0009060	biological_process	aerobic respiration
an	0016020	cellular_component	membrane
an	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
an	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
an	0045271	cellular_component	respiratory chain complex I
ao	0005524	molecular_function	ATP binding
ao	0005634	cellular_component	nucleus
ao	0005654	cellular_component	nucleoplasm
ao	0005737	cellular_component	cytoplasm
ao	0005739	cellular_component	mitochondrion
ao	0005743	cellular_component	mitochondrial inner membrane
ao	0006915	biological_process	apoptotic process
ao	0009060	biological_process	aerobic respiration
ao	0016020	cellular_component	membrane
ao	0031966	cellular_component	mitochondrial membrane
ao	0032981	biological_process	mitochondrial respiratory chain complex I assembly
ao	0035458	biological_process	cellular response to interferon-beta
ao	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
ao	0045039	biological_process	protein insertion into mitochondrial inner membrane
ao	0045271	cellular_component	respiratory chain complex I
ao	0045732	biological_process	positive regulation of protein catabolic process
ao	0045892	biological_process	negative regulation of DNA-templated transcription
ao	0071300	biological_process	cellular response to retinoic acid
ao	0097191	biological_process	extrinsic apoptotic signaling pathway
ao	0098803	cellular_component	respiratory chain complex
ao	1900119	biological_process	positive regulation of execution phase of apoptosis
b1	0005739	cellular_component	mitochondrion
b1	0005743	cellular_component	mitochondrial inner membrane
b1	0009060	biological_process	aerobic respiration
b1	0016020	cellular_component	membrane
b1	0016607	cellular_component	nuclear speck
b1	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
b1	0045271	cellular_component	respiratory chain complex I
b2	0003674	molecular_function	molecular_function
b2	0005739	cellular_component	mitochondrion
b2	0005743	cellular_component	mitochondrial inner membrane
b2	0009060	biological_process	aerobic respiration
b2	0016020	cellular_component	membrane
b2	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
b2	0045271	cellular_component	respiratory chain complex I
b3	0003674	molecular_function	molecular_function
b3	0005739	cellular_component	mitochondrion
b3	0005743	cellular_component	mitochondrial inner membrane
b3	0009060	biological_process	aerobic respiration
b3	0016020	cellular_component	membrane
b3	0022900	biological_process	electron transport chain
b3	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
b3	0045271	cellular_component	respiratory chain complex I
b4	0003674	molecular_function	molecular_function
b4	0005654	cellular_component	nucleoplasm
b4	0005739	cellular_component	mitochondrion
b4	0005743	cellular_component	mitochondrial inner membrane
b4	0009060	biological_process	aerobic respiration
b4	0016020	cellular_component	membrane
b4	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
b4	0045271	cellular_component	respiratory chain complex I
b5	0003674	molecular_function	molecular_function
b5	0005654	cellular_component	nucleoplasm
b5	0005739	cellular_component	mitochondrion
b5	0005743	cellular_component	mitochondrial inner membrane
b5	0009060	biological_process	aerobic respiration
b5	0016020	cellular_component	membrane
b5	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
b5	0045271	cellular_component	respiratory chain complex I
b6	0005654	cellular_component	nucleoplasm
b6	0005739	cellular_component	mitochondrion
b6	0005743	cellular_component	mitochondrial inner membrane
b6	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
b6	0009060	biological_process	aerobic respiration
b6	0016020	cellular_component	membrane
b6	0031966	cellular_component	mitochondrial membrane
b6	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
b6	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
b6	0045271	cellular_component	respiratory chain complex I
b7	0003674	molecular_function	molecular_function
b7	0005739	cellular_component	mitochondrion
b7	0005743	cellular_component	mitochondrial inner membrane
b7	0005758	cellular_component	mitochondrial intermembrane space
b7	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
b7	0009060	biological_process	aerobic respiration
b7	0016020	cellular_component	membrane
b7	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
b7	0045271	cellular_component	respiratory chain complex I
b7	1902600	biological_process	proton transmembrane transport
b8	0003674	molecular_function	molecular_function
b8	0005739	cellular_component	mitochondrion
b8	0005743	cellular_component	mitochondrial inner membrane
b8	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
b8	0009060	biological_process	aerobic respiration
b8	0016020	cellular_component	membrane
b8	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
b8	0045271	cellular_component	respiratory chain complex I
b9	0005739	cellular_component	mitochondrion
b9	0005743	cellular_component	mitochondrial inner membrane
b9	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
b9	0009060	biological_process	aerobic respiration
b9	0016020	cellular_component	membrane
b9	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
b9	0045271	cellular_component	respiratory chain complex I
bl	0005739	cellular_component	mitochondrion
bl	0005743	cellular_component	mitochondrial inner membrane
bl	0009060	biological_process	aerobic respiration
bl	0016020	cellular_component	membrane
bl	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
bl	0045271	cellular_component	respiratory chain complex I
bm	0003674	molecular_function	molecular_function
bm	0005739	cellular_component	mitochondrion
bm	0005743	cellular_component	mitochondrial inner membrane
bm	0009060	biological_process	aerobic respiration
bm	0016020	cellular_component	membrane
bm	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
bm	0045271	cellular_component	respiratory chain complex I
c1	0003674	molecular_function	molecular_function
c1	0005739	cellular_component	mitochondrion
c1	0005743	cellular_component	mitochondrial inner membrane
c1	0009060	biological_process	aerobic respiration
c1	0016020	cellular_component	membrane
c1	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
c1	0045271	cellular_component	respiratory chain complex I
c2	0005737	cellular_component	cytoplasm
c2	0005739	cellular_component	mitochondrion
c2	0005743	cellular_component	mitochondrial inner membrane
c2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
c2	0009060	biological_process	aerobic respiration
c2	0010918	biological_process	positive regulation of mitochondrial membrane potential
c2	0016020	cellular_component	membrane
c2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
c2	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
c2	0045271	cellular_component	respiratory chain complex I
c2	1901223	biological_process	negative regulation of non-canonical NF-kappaB signal transduction
c2	1903427	biological_process	negative regulation of reactive oxygen species biosynthetic process
c2	2001171	biological_process	positive regulation of ATP biosynthetic process
s1	0005515	molecular_function	protein binding
s1	0005739	cellular_component	mitochondrion
s1	0005743	cellular_component	mitochondrial inner membrane
s1	0005758	cellular_component	mitochondrial intermembrane space
s1	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
s1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
s1	0009055	molecular_function	electron transfer activity
s1	0009060	biological_process	aerobic respiration
s1	0016020	cellular_component	membrane
s1	0016491	molecular_function	oxidoreductase activity
s1	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
s1	0032981	biological_process	mitochondrial respiratory chain complex I assembly
s1	0042773	biological_process	ATP synthesis coupled electron transport
s1	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
s1	0043209	cellular_component	myelin sheath
s1	0045271	cellular_component	respiratory chain complex I
s1	0045333	biological_process	cellular respiration
s1	0046872	molecular_function	metal ion binding
s1	0051536	molecular_function	iron-sulfur cluster binding
s1	0051537	molecular_function	2 iron, 2 sulfur cluster binding
s1	0051539	molecular_function	4 iron, 4 sulfur cluster binding
s1	1902600	biological_process	proton transmembrane transport
s2	0003954	molecular_function	NADH dehydrogenase activity
s2	0005515	molecular_function	protein binding
s2	0005739	cellular_component	mitochondrion
s2	0005743	cellular_component	mitochondrial inner membrane
s2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
s2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
s2	0009060	biological_process	aerobic respiration
s2	0016020	cellular_component	membrane
s2	0016491	molecular_function	oxidoreductase activity
s2	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
s2	0019826	molecular_function	oxygen sensor activity
s2	0022008	biological_process	neurogenesis
s2	0031625	molecular_function	ubiquitin protein ligase binding
s2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
s2	0042063	biological_process	gliogenesis
s2	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
s2	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
s2	0045271	cellular_component	respiratory chain complex I
s2	0046872	molecular_function	metal ion binding
s2	0048038	molecular_function	quinone binding
s2	0051287	molecular_function	NAD binding
s2	0051536	molecular_function	iron-sulfur cluster binding
s2	0051539	molecular_function	4 iron, 4 sulfur cluster binding
s2	0061351	biological_process	neural precursor cell proliferation
s2	0071453	biological_process	cellular response to oxygen levels
s2	1902600	biological_process	proton transmembrane transport
s3	0003954	molecular_function	NADH dehydrogenase activity
s3	0005515	molecular_function	protein binding
s3	0005739	cellular_component	mitochondrion
s3	0005743	cellular_component	mitochondrial inner membrane
s3	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
s3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
s3	0009060	biological_process	aerobic respiration
s3	0016020	cellular_component	membrane
s3	0016491	molecular_function	oxidoreductase activity
s3	0016604	cellular_component	nuclear body
s3	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
s3	0031966	cellular_component	mitochondrial membrane
s3	0032981	biological_process	mitochondrial respiratory chain complex I assembly
s3	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
s3	0043209	cellular_component	myelin sheath
s3	0045271	cellular_component	respiratory chain complex I
s3	0072593	biological_process	reactive oxygen species metabolic process
s3	1902600	biological_process	proton transmembrane transport
s4	0003016	biological_process	respiratory system process
s4	0005739	cellular_component	mitochondrion
s4	0005743	cellular_component	mitochondrial inner membrane
s4	0006099	biological_process	tricarboxylic acid cycle
s4	0006954	biological_process	inflammatory response
s4	0007420	biological_process	brain development
s4	0007601	biological_process	visual perception
s4	0007605	biological_process	sensory perception of sound
s4	0007628	biological_process	adult walking behavior
s4	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
s4	0009060	biological_process	aerobic respiration
s4	0014876	biological_process	response to injury involved in regulation of muscle adaptation
s4	0016020	cellular_component	membrane
s4	0022900	biological_process	electron transport chain
s4	0022904	biological_process	respiratory electron transport chain
s4	0030534	biological_process	adult behavior
s4	0032981	biological_process	mitochondrial respiratory chain complex I assembly
s4	0036343	biological_process	psychomotor behavior
s4	0042417	biological_process	dopamine metabolic process
s4	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
s4	0045087	biological_process	innate immune response
s4	0045271	cellular_component	respiratory chain complex I
s4	0048666	biological_process	neuron development
s4	0050890	biological_process	cognition
s4	0051402	biological_process	neuron apoptotic process
s4	0051881	biological_process	regulation of mitochondrial membrane potential
s4	0071453	biological_process	cellular response to oxygen levels
s4	0072593	biological_process	reactive oxygen species metabolic process
s4	1902600	biological_process	proton transmembrane transport
s5	0003674	molecular_function	molecular_function
s5	0005739	cellular_component	mitochondrion
s5	0005743	cellular_component	mitochondrial inner membrane
s5	0005758	cellular_component	mitochondrial intermembrane space
s5	0009060	biological_process	aerobic respiration
s5	0016020	cellular_component	membrane
s5	0032981	biological_process	mitochondrial respiratory chain complex I assembly
s5	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
s5	0045271	cellular_component	respiratory chain complex I
s6	0001822	biological_process	kidney development
s6	0003674	molecular_function	molecular_function
s6	0005739	cellular_component	mitochondrion
s6	0005743	cellular_component	mitochondrial inner membrane
s6	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
s6	0006631	biological_process	fatty acid metabolic process
s6	0006936	biological_process	muscle contraction
s6	0007005	biological_process	mitochondrion organization
s6	0009060	biological_process	aerobic respiration
s6	0010467	biological_process	gene expression
s6	0016020	cellular_component	membrane
s6	0017145	biological_process	stem cell division
s6	0022904	biological_process	respiratory electron transport chain
s6	0030330	biological_process	DNA damage response, signal transduction by p53 class mediator
s6	0032981	biological_process	mitochondrial respiratory chain complex I assembly
s6	0035264	biological_process	multicellular organism growth
s6	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
s6	0045271	cellular_component	respiratory chain complex I
s6	0051881	biological_process	regulation of mitochondrial membrane potential
s6	0061458	biological_process	reproductive system development
s6	0072359	biological_process	circulatory system development
s6	0072497	biological_process	mesenchymal stem cell differentiation
s6	0072593	biological_process	reactive oxygen species metabolic process
s6	0090398	biological_process	cellular senescence
s6	0097168	biological_process	mesenchymal stem cell proliferation
s7	0003954	molecular_function	NADH dehydrogenase activity
s7	0004497	molecular_function	monooxygenase activity
s7	0005739	cellular_component	mitochondrion
s7	0005743	cellular_component	mitochondrial inner membrane
s7	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
s7	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
s7	0009060	biological_process	aerobic respiration
s7	0015990	biological_process	electron transport coupled proton transport
s7	0016020	cellular_component	membrane
s7	0016491	molecular_function	oxidoreductase activity
s7	0032981	biological_process	mitochondrial respiratory chain complex I assembly
s7	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
s7	0045271	cellular_component	respiratory chain complex I
s7	0046872	molecular_function	metal ion binding
s7	0048038	molecular_function	quinone binding
s7	0051536	molecular_function	iron-sulfur cluster binding
s7	0051539	molecular_function	4 iron, 4 sulfur cluster binding
s8	0003954	molecular_function	NADH dehydrogenase activity
s8	0005515	molecular_function	protein binding
s8	0005739	cellular_component	mitochondrion
s8	0005743	cellular_component	mitochondrial inner membrane
s8	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
s8	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
s8	0009060	biological_process	aerobic respiration
s8	0016020	cellular_component	membrane
s8	0016491	molecular_function	oxidoreductase activity
s8	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
s8	0032981	biological_process	mitochondrial respiratory chain complex I assembly
s8	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
s8	0045271	cellular_component	respiratory chain complex I
s8	0046872	molecular_function	metal ion binding
s8	0051536	molecular_function	iron-sulfur cluster binding
s8	0051539	molecular_function	4 iron, 4 sulfur cluster binding
s8	1902600	biological_process	proton transmembrane transport
v1	0005515	molecular_function	protein binding
v1	0005739	cellular_component	mitochondrion
v1	0005743	cellular_component	mitochondrial inner membrane
v1	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
v1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
v1	0009060	biological_process	aerobic respiration
v1	0010181	molecular_function	FMN binding
v1	0016020	cellular_component	membrane
v1	0016491	molecular_function	oxidoreductase activity
v1	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
v1	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
v1	0045271	cellular_component	respiratory chain complex I
v1	0046872	molecular_function	metal ion binding
v1	0051287	molecular_function	NAD binding
v1	0051536	molecular_function	iron-sulfur cluster binding
v1	0051539	molecular_function	4 iron, 4 sulfur cluster binding
v1	1902600	biological_process	proton transmembrane transport
v2	0003954	molecular_function	NADH dehydrogenase activity
v2	0005739	cellular_component	mitochondrion
v2	0005743	cellular_component	mitochondrial inner membrane
v2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
v2	0007399	biological_process	nervous system development
v2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
v2	0009060	biological_process	aerobic respiration
v2	0016020	cellular_component	membrane
v2	0016491	molecular_function	oxidoreductase activity
v2	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
v2	0043209	cellular_component	myelin sheath
v2	0045271	cellular_component	respiratory chain complex I
v2	0046872	molecular_function	metal ion binding
v2	0048738	biological_process	cardiac muscle tissue development
v2	0051536	molecular_function	iron-sulfur cluster binding
v2	0051537	molecular_function	2 iron, 2 sulfur cluster binding
v2	1902600	biological_process	proton transmembrane transport
v3	0005739	cellular_component	mitochondrion
v3	0005743	cellular_component	mitochondrial inner membrane
v3	0009060	biological_process	aerobic respiration
v3	0016020	cellular_component	membrane
v3	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
v3	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
v3	0045271	cellular_component	respiratory chain complex I

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM

Chain	Residue	Details
ab	ASP107-MET122

---

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI

Chain	Residue	Details
ab	ASP132-ILE144

---

site_id	PS00143
Number of Residues	24
Details	INSULINASE Insulinase family, zinc-binding region signature. GsryedsnnlGtSHLLRLAsSlTT

Chain	Residue	Details
3B	GLY68-THR91

---

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaICP

Chain	Residue	Details
S8	CYS113-PRO124
S8	CYS152-PRO163

---

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
S2	LEU116-LYS127

---

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREvwDMFgvfffnHpdlRrIL

Chain	Residue	Details
S3	GLU166-LEU187

---

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC

Chain	Residue	Details
s1	PRO61-CYS78

---

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ

Chain	Residue	Details
s1	CYS128-GLN140

---

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF

Chain	Residue	Details
s1	ARG175-PHE185

---

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES

Chain	Residue	Details
v1	GLY200-SER215

---

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
v1	GLU377-GLY388

---

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GILQpFaDAMKLFmKE

Chain	Residue	Details
1	GLY44-GLU59

---

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTEGEseLVs.G

Chain	Residue	Details
1	PRO197-GLY210

---

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP

Chain	Residue	Details
v2	ASP165-PRO183

---

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP

Chain	Residue	Details
S7	GLY180-PRO196

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2320
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	54
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"23576753","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Symmetric dimethylarginine","evidences":[{"source":"UniProtKB","id":"P17694","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	16
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"23806337","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by PINK1","evidences":[{"source":"PubMed","id":"24652937","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"23806337","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20433953","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	4
Details	Modified residue: {"description":"O-(pantetheine 4'-phosphoryl)serine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	150
Details	Domain: {"description":"Carrier","evidences":[{"source":"PROSITE-ProRule","id":"PRU00258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q16718","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q63362","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	82
Details	Domain: {"description":"CHCH 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	86
Details	Domain: {"description":"CHCH 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	60
Details	Motif: {"description":"Cx9C motif 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	60
Details	Motif: {"description":"Cx9C motif 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	20
Details	Motif: {"description":"Cx9C motif 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	20
Details	Motif: {"description":"Cx9C motif 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	104
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	2
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"UniProtKB","id":"Q02371","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	172
Details	Domain: {"description":"CHCH","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	35
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	2
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"UniProtKB","id":"Q9Y6M9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9Y6M9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	1
Details	Lipidation: {"description":"N-myristoyl glycine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	20
Details	Compositional bias: {"description":"Pro residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O96000","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"O95182","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P56181","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q68FY0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q68FY0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P32551","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	504
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7O3C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	2
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00968","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7O3C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	10
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7O3C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P00157","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	404
Details	Topological domain: {"description":"Mitochondrial intermembrane","evidences":[{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7O3C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	31
Details	Topological domain: {"description":"Mitochondrial matrix","evidences":[{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7O3C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	202
Details	Domain: {"description":"Cytochrome c","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	4
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7O3C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	62
Details	Topological domain: {"description":"Mitochondrial matrix","evidences":[{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	52
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O14949","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	114
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29915388","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6G2J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6G72","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	2
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine; by SRC","evidences":[{"source":"UniProtKB","id":"P19404","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	156
Details	Domain: {"description":"2Fe-2S ferredoxin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00465","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	78
Details	Domain: {"description":"4Fe-4S His(Cys)3-ligated-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01184","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI52
Number of Residues	112
Details	Domain: {"description":"4Fe-4S Mo/W bis-MGD-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01004","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI53
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"38575788","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI54
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01184","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"38575788","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI55
Number of Residues	58
Details	Domain: {"description":"4Fe-4S ferredoxin-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"38575788","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI56
Number of Residues	58
Details	Domain: {"description":"4Fe-4S ferredoxin-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"38575788","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI57
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"38575788","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---