8U39

Structure of Human Mitochondrial Chaperonin V72I mutant

Functional Information from PROSITE/UniProt

site_id	PS00296
Number of Residues	12
Details	CHAPERONINS_CPN60 Chaperonins cpn60 signature. AAVEEGIVlGGG

Chain	Residue	Details
G	ALA404-GLY415

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	BINDING: BINDING => ECO:0000269|PubMed:25918392, ECO:0007744|PDB:4PJ1

Chain	Residue	Details
G	LYS49
B	ASP85
B	GLY414
B	ASP494
C	LYS49
C	ASP85
C	GLY414
C	ASP494
D	LYS49
D	ASP85
D	GLY414
G	ASP85
D	ASP494
E	LYS49
E	ASP85
E	GLY414
E	ASP494
F	LYS49
F	ASP85
F	GLY414
F	ASP494
G	GLY414
G	ASP494
A	LYS49
A	ASP85
A	GLY414
A	ASP494
B	LYS49

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P63038

Chain	Residue	Details
G	LYS5
D	LYS275
E	LYS5
E	LYS275
F	LYS5
F	LYS275
G	LYS275
A	LYS5
A	LYS275
B	LYS5
B	LYS275
C	LYS5
C	LYS275
D	LYS5

---

site_id	SWS_FT_FI3
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
G	SER41
A	SER41
B	SER41
C	SER41
D	SER41
E	SER41
F	SER41

---

site_id	SWS_FT_FI4
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
G	SER44
A	SER44
B	SER44
C	SER44
D	SER44
E	SER44
F	SER44

---

site_id	SWS_FT_FI5
Number of Residues	56
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P63038

Chain	Residue	Details
G	LYS49
A	LYS61
A	LYS65
A	LYS130
A	LYS223
A	LYS266
A	LYS288
A	LYS363
B	LYS49
B	LYS61
B	LYS65
G	LYS61
B	LYS130
B	LYS223
B	LYS266
B	LYS288
B	LYS363
C	LYS49
C	LYS61
C	LYS65
C	LYS130
C	LYS223
G	LYS65
C	LYS266
C	LYS288
C	LYS363
D	LYS49
D	LYS61
D	LYS65
D	LYS130
D	LYS223
D	LYS266
D	LYS288
G	LYS130
D	LYS363
E	LYS49
E	LYS61
E	LYS65
E	LYS130
E	LYS223
E	LYS266
E	LYS288
E	LYS363
F	LYS49
G	LYS223
F	LYS61
F	LYS65
F	LYS130
F	LYS223
F	LYS266
F	LYS288
F	LYS363
G	LYS266
G	LYS288
G	LYS363
A	LYS49

---

site_id	SWS_FT_FI6
Number of Residues	84
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P63038

Chain	Residue	Details
G	LYS56
G	LYS326
G	LYS370
G	LYS455
A	LYS56
A	LYS99
A	LYS107
A	LYS165
A	LYS176
A	LYS179
A	LYS192
G	LYS99
A	LYS210
A	LYS224
A	LYS326
A	LYS370
A	LYS455
B	LYS56
B	LYS99
B	LYS107
B	LYS165
B	LYS176
G	LYS107
B	LYS179
B	LYS192
B	LYS210
B	LYS224
B	LYS326
B	LYS370
B	LYS455
C	LYS56
C	LYS99
C	LYS107
G	LYS165
C	LYS165
C	LYS176
C	LYS179
C	LYS192
C	LYS210
C	LYS224
C	LYS326
C	LYS370
C	LYS455
D	LYS56
G	LYS176
D	LYS99
D	LYS107
D	LYS165
D	LYS176
D	LYS179
D	LYS192
D	LYS210
D	LYS224
D	LYS326
D	LYS370
G	LYS179
D	LYS455
E	LYS56
E	LYS99
E	LYS107
E	LYS165
E	LYS176
E	LYS179
E	LYS192
E	LYS210
E	LYS224
G	LYS192
E	LYS326
E	LYS370
E	LYS455
F	LYS56
F	LYS99
F	LYS107
F	LYS165
F	LYS176
F	LYS179
F	LYS192
G	LYS210
F	LYS210
F	LYS224
F	LYS326
F	LYS370
F	LYS455
G	LYS224

---

site_id	SWS_FT_FI7
Number of Residues	7
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
G	TYR64
A	TYR64
B	TYR64
C	TYR64
D	TYR64
E	TYR64
F	TYR64

---

site_id	SWS_FT_FI8
Number of Residues	28
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
G	LYS104
B	LYS243
B	LYS333
B	LYS443
C	LYS104
C	LYS243
C	LYS333
C	LYS443
D	LYS104
D	LYS243
D	LYS333
G	LYS243
D	LYS443
E	LYS104
E	LYS243
E	LYS333
E	LYS443
F	LYS104
F	LYS243
F	LYS333
F	LYS443
G	LYS333
G	LYS443
A	LYS104
A	LYS243
A	LYS333
A	LYS443
B	LYS104

---

site_id	SWS_FT_FI9
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P63038

Chain	Residue	Details
G	SER384
A	SER384
B	SER384
C	SER384
D	SER384
E	SER384
F	SER384

---

site_id	SWS_FT_FI10
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
G	SER462
A	SER462
B	SER462
C	SER462
D	SER462
E	SER462
F	SER462

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