8TZI
Human equilibrative nucleoside transporter-1, JH-ENT-01 bound
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 76 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:11584005 |
| Chain | Residue | Details |
| A | THR2-LYS12 | |
| A | GLN108-ARG111 | |
| A | ARG228-THR323 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 214 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | ALA13-TRP29 | |
| A | GLU426-GLY445 | |
| A | VAL83-PRO107 | |
| A | ILE112-VAL130 | |
| A | PHE139-LEU157 | |
| A | ALA175-SER199 | |
| A | GLY207-PRO227 | |
| A | TRP324-LEU343 | |
| A | LYS356-LEU374 | |
| A | HIS392-LEU410 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 93 |
| Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:11584005 |
| Chain | Residue | Details |
| A | ASN30-ASN82 | |
| A | LYS131-PRO138 | |
| A | GLU200-PHE206 | |
| A | GLY344-GLY355 | |
| A | ALA411-ALA425 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 49 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | GLN158-ALA174 | |
| A | LEU375-GLU391 | |
| A | ALA446-VAL463 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | SITE: Not glycosylated => ECO:0000269|PubMed:11584005 |
| Chain | Residue | Details |
| A | ALA309 | |
| A | GLY320 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | SITE: Essential for nucleobase transport => ECO:0000269|PubMed:21795683 |
| Chain | Residue | Details |
| A | ALA446 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | LEU286 | |
| A | THR301 | |
| A | GLY305 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:11584005, ECO:0000269|PubMed:19349973 |
| Chain | Residue | Details |
| A | ASN48 |
