8TW4

TCR in nanodisc ND-I

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002250	biological_process	adaptive immune response
A	0002376	biological_process	immune system process
A	0005886	cellular_component	plasma membrane
A	0009617	biological_process	response to bacterium
A	0016020	cellular_component	membrane
A	0042101	cellular_component	T cell receptor complex
A	0042105	cellular_component	alpha-beta T cell receptor complex
A	0046631	biological_process	alpha-beta T cell activation
A	0050852	biological_process	T cell receptor signaling pathway
B	0006091	biological_process	generation of precursor metabolites and energy
B	0008218	biological_process	bioluminescence
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0007166	biological_process	cell surface receptor signaling pathway
D	0016020	cellular_component	membrane
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0007166	biological_process	cell surface receptor signaling pathway
E	0016020	cellular_component	membrane
F	0004888	molecular_function	transmembrane signaling receptor activity
F	0007166	biological_process	cell surface receptor signaling pathway
F	0016020	cellular_component	membrane
G	0004888	molecular_function	transmembrane signaling receptor activity
G	0007166	biological_process	cell surface receptor signaling pathway
G	0016020	cellular_component	membrane
X	0004888	molecular_function	transmembrane signaling receptor activity
X	0006091	biological_process	generation of precursor metabolites and energy
X	0007166	biological_process	cell surface receptor signaling pathway
X	0008218	biological_process	bioluminescence
X	0016020	cellular_component	membrane
Y	0004888	molecular_function	transmembrane signaling receptor activity
Y	0006091	biological_process	generation of precursor metabolites and energy
Y	0007166	biological_process	cell surface receptor signaling pathway
Y	0008218	biological_process	bioluminescence
Y	0016020	cellular_component	membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	TRANSMEM: Helical => ECO:0000255, ECO:0000269|PubMed:27791034

Chain	Residue	Details
A	VAL250-TRP272
Y	GLN22-LYS30

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site_id	SWS_FT_FI2
Number of Residues	1
Details	TOPO_DOM: Cytoplasmic => ECO:0000255

Chain	Residue	Details
A	SER273-SER274
Y	LEU31-LEU51

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site_id	SWS_FT_FI3
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498, ECO:0000269|PubMed:19349973

Chain	Residue	Details
A	ASN166
A	ASN200

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site_id	SWS_FT_FI4
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498

Chain	Residue	Details
A	ASN211
A	ASN247

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site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:15144186, ECO:0007744|PubMed:15592455, ECO:0007744|PubMed:19690332

Chain	Residue	Details
X	TYR64
X	TYR72
Y	TYR64
Y	TYR72

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site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:12522270

Chain	Residue	Details
X	TYR83
Y	TYR83

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site_id	SWS_FT_FI7
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:12522270, ECO:0007744|PubMed:15144186, ECO:0007744|PubMed:15592455, ECO:0007744|PubMed:19690332

Chain	Residue	Details
X	TYR111
X	TYR142
Y	TYR111
Y	TYR142

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site_id	SWS_FT_FI8
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
X	TYR123
X	TYR153
Y	TYR123
Y	TYR153

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