8TRQ
T cell recognition of citrullinated vimentin peptide presented by HLA-DR4
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCQVEH |
| Chain | Residue | Details |
| B | TYR171-HIS177 | |
| A | TYR161-HIS167 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| C | TYR61 | |
| B | TRP61 | |
| B | HIS81 | |
| B | ASN82 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| C | SER66 | |
| A | ALA52 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19303388, ECO:0000269|PubMed:24190431 |
| Chain | Residue | Details |
| B | ASN19 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819 |
| Chain | Residue | Details |
| A | SER53 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | SITE: Pathogen-derived peptide antigen => ECO:0000269|PubMed:23260142, ECO:0007744|PDB:4GBX |
| Chain | Residue | Details |
| A | GLU55 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4GBX |
| Chain | Residue | Details |
| A | ASN62 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | SITE: Pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX |
| Chain | Residue | Details |
| A | ASN69 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX |
| Chain | Residue | Details |
| A | ARG76 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400 |
| Chain | Residue | Details |
| A | ASN78 | |
| A | ASN118 |
