8T5P

SARS-CoV-2 ORF3a peptide in complex with TRAF3 TRAF domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001817	biological_process	regulation of cytokine production
A	0005164	molecular_function	tumor necrosis factor receptor binding
A	0008063	biological_process	Toll signaling pathway
A	0032088	biological_process	negative regulation of NF-kappaB transcription factor activity
A	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
A	0045087	biological_process	innate immune response
A	0050688	biological_process	regulation of defense response to virus
B	0001817	biological_process	regulation of cytokine production
B	0005164	molecular_function	tumor necrosis factor receptor binding
B	0008063	biological_process	Toll signaling pathway
B	0032088	biological_process	negative regulation of NF-kappaB transcription factor activity
B	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
B	0045087	biological_process	innate immune response
B	0050688	biological_process	regulation of defense response to virus
C	0001817	biological_process	regulation of cytokine production
C	0005164	molecular_function	tumor necrosis factor receptor binding
C	0008063	biological_process	Toll signaling pathway
C	0032088	biological_process	negative regulation of NF-kappaB transcription factor activity
C	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
C	0045087	biological_process	innate immune response
C	0050688	biological_process	regulation of defense response to virus
D	0001817	biological_process	regulation of cytokine production
D	0005164	molecular_function	tumor necrosis factor receptor binding
D	0008063	biological_process	Toll signaling pathway
D	0032088	biological_process	negative regulation of NF-kappaB transcription factor activity
D	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
D	0045087	biological_process	innate immune response
D	0050688	biological_process	regulation of defense response to virus
E	0001817	biological_process	regulation of cytokine production
E	0005164	molecular_function	tumor necrosis factor receptor binding
E	0008063	biological_process	Toll signaling pathway
E	0032088	biological_process	negative regulation of NF-kappaB transcription factor activity
E	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
E	0045087	biological_process	innate immune response
E	0050688	biological_process	regulation of defense response to virus
F	0001817	biological_process	regulation of cytokine production
F	0005164	molecular_function	tumor necrosis factor receptor binding
F	0008063	biological_process	Toll signaling pathway
F	0032088	biological_process	negative regulation of NF-kappaB transcription factor activity
F	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
F	0045087	biological_process	innate immune response
F	0050688	biological_process	regulation of defense response to virus

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	870
Details	Domain: {"description":"MATH","evidences":[{"source":"PROSITE-ProRule","id":"PRU00129","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	138
Details	Region: {"description":"(Microbial infection) Interaction with glycoprotein N of Andes and New York hantaviruses","evidences":[{"source":"PubMed","id":"24390324","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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