8SZ8
Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state (full helix)
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| b | 0003924 | molecular_function | GTPase activity |
| b | 0005525 | molecular_function | GTP binding |
| c | 0003924 | molecular_function | GTPase activity |
| c | 0005525 | molecular_function | GTP binding |
| f | 0003924 | molecular_function | GTPase activity |
| f | 0005525 | molecular_function | GTP binding |
| g | 0003924 | molecular_function | GTPase activity |
| g | 0005525 | molecular_function | GTP binding |
Functional Information from PROSITE/UniProt
| site_id | PS00410 |
| Number of Residues | 10 |
| Details | G_DYNAMIN_1 Dynamin-type guanine nucleotide-binding (G) domain signature. LPRGSGIVTR |
| Chain | Residue | Details |
| b | LEU57-ARG66 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1064 |
| Details | Domain: {"description":"Dynamin-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 28 |
| Details | Region: {"description":"G1 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Region: {"description":"G2 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Region: {"description":"G3 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 12 |
| Details | Region: {"description":"G4 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | Region: {"description":"G5 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20428113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26612256","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5D3Q","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20428113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26612256","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2X2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2X2F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D3Q","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20428113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26612256","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30069048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2X2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2X2F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D3Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DLU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26612256","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5D3Q","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20428113","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2X2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2X2F","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20428113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26612256","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30069048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2X2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D3Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DLU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P39053","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphotyrosine; alternate","evidences":[{"source":"UniProtKB","id":"P39053","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P39053","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P21575","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
