8SRM

Structure of human ULK1 complex core (2:2:2 stoichiometry) of the ATG13(450-517) mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000045	biological_process	autophagosome assembly
B	0000045	biological_process	autophagosome assembly
C	0004674	molecular_function	protein serine/threonine kinase activity
D	0004674	molecular_function	protein serine/threonine kinase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphoserine; by ULK1 => ECO:0000269|PubMed:21855797, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
E	GLN471
F	GLN471
A	SER253
A	SER266
B	SER222
B	SER229
B	SER253
B	SER266

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
E	ASN472
F	ASN472

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
E	SER477
F	SER477

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER243
A	SER257
B	SER243
B	SER257

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9ESK9

Chain	Residue	Details
A	SER261
B	SER261

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	SER624
B	SER624

---