8S4Y

Crystal structure of an APP-talin (F2F3) chimera

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005856	cellular_component	cytoskeleton

Functional Information from PROSITE/UniProt

site_id	PS00320
Number of Residues	8
Details	APP_INTRA Amyloid precursor protein (APP) intracellular domain signature. GYENPTYK

Chain	Residue	Details
A	GLY756-LYS763

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site_id	PS00661
Number of Residues	30
Details	FERM_2 FERM domain signature 2. HkncgnmseiEAkvrYVkl.ArsLktYGvSF

Chain	Residue	Details
B	HIS283-PHE312

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphotyrosine; by ABL1 => ECO:0000269|PubMed:11279131

Chain	Residue	Details
A	TYR757

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P08592

Chain	Residue	Details
A	LYS763

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