Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8S1U

YlmH bound to stalled 50S subunits with RqcH and PtRNA

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0003735	molecular_function	structural constituent of ribosome
0	0005840	cellular_component	ribosome
0	0006412	biological_process	translation
0	0015934	cellular_component	large ribosomal subunit
0	1990904	cellular_component	ribonucleoprotein complex
1	0003735	molecular_function	structural constituent of ribosome
1	0005737	cellular_component	cytoplasm
1	0005840	cellular_component	ribosome
1	0006412	biological_process	translation
1	1990904	cellular_component	ribonucleoprotein complex
2	0003735	molecular_function	structural constituent of ribosome
2	0005840	cellular_component	ribosome
2	0006412	biological_process	translation
2	1990904	cellular_component	ribonucleoprotein complex
3	0003735	molecular_function	structural constituent of ribosome
3	0005840	cellular_component	ribosome
3	0006412	biological_process	translation
3	0022625	cellular_component	cytosolic large ribosomal subunit
3	1990904	cellular_component	ribonucleoprotein complex
4	0003735	molecular_function	structural constituent of ribosome
4	0005737	cellular_component	cytoplasm
4	0005840	cellular_component	ribosome
4	0006412	biological_process	translation
4	1990904	cellular_component	ribonucleoprotein complex
6	0003723	molecular_function	RNA binding
6	0003735	molecular_function	structural constituent of ribosome
6	0005840	cellular_component	ribosome
6	0006412	biological_process	translation
6	0019843	molecular_function	rRNA binding
6	0046872	molecular_function	metal ion binding
6	1990904	cellular_component	ribonucleoprotein complex
C	0002181	biological_process	cytoplasmic translation
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
C	0015934	cellular_component	large ribosomal subunit
C	0016740	molecular_function	transferase activity
C	0019843	molecular_function	rRNA binding
C	1990904	cellular_component	ribonucleoprotein complex
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005840	cellular_component	ribosome
D	0006364	biological_process	rRNA processing
D	0006412	biological_process	translation
D	0019843	molecular_function	rRNA binding
D	0022625	cellular_component	cytosolic large ribosomal subunit
D	1990904	cellular_component	ribonucleoprotein complex
D	2000234	biological_process	positive regulation of rRNA processing
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0019843	molecular_function	rRNA binding
E	1990904	cellular_component	ribonucleoprotein complex
F	0000049	molecular_function	tRNA binding
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0019843	molecular_function	rRNA binding
F	0022625	cellular_component	cytosolic large ribosomal subunit
F	1990904	cellular_component	ribonucleoprotein complex
G	0002181	biological_process	cytoplasmic translation
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005515	molecular_function	protein binding
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0019843	molecular_function	rRNA binding
G	0022625	cellular_component	cytosolic large ribosomal subunit
G	1990904	cellular_component	ribonucleoprotein complex
H	0000049	molecular_function	tRNA binding
H	0003723	molecular_function	RNA binding
H	0006412	biological_process	translation
H	0019843	molecular_function	rRNA binding
H	0043023	molecular_function	ribosomal large subunit binding
H	0072344	biological_process	rescue of stalled ribosome
H	1990112	cellular_component	RQC complex
J	0003729	molecular_function	mRNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0017148	biological_process	negative regulation of translation
J	0022625	cellular_component	cytosolic large ribosomal subunit
J	1990904	cellular_component	ribonucleoprotein complex
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0015934	cellular_component	large ribosomal subunit
K	0019843	molecular_function	rRNA binding
K	0022625	cellular_component	cytosolic large ribosomal subunit
K	0070180	molecular_function	large ribosomal subunit rRNA binding
K	1990904	cellular_component	ribonucleoprotein complex
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0015934	cellular_component	large ribosomal subunit
L	0019843	molecular_function	rRNA binding
L	0022625	cellular_component	cytosolic large ribosomal subunit
L	1990904	cellular_component	ribonucleoprotein complex
M	0000049	molecular_function	tRNA binding
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0019843	molecular_function	rRNA binding
M	0022625	cellular_component	cytosolic large ribosomal subunit
M	1990904	cellular_component	ribonucleoprotein complex
N	0003735	molecular_function	structural constituent of ribosome
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0022625	cellular_component	cytosolic large ribosomal subunit
N	1990904	cellular_component	ribonucleoprotein complex
O	0003723	molecular_function	RNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005737	cellular_component	cytoplasm
O	0005840	cellular_component	ribosome
O	0006364	biological_process	rRNA processing
O	0006412	biological_process	translation
O	0008097	molecular_function	5S rRNA binding
O	0019843	molecular_function	rRNA binding
O	0022625	cellular_component	cytosolic large ribosomal subunit
O	1990904	cellular_component	ribonucleoprotein complex
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0022625	cellular_component	cytosolic large ribosomal subunit
P	1990904	cellular_component	ribonucleoprotein complex
Q	0000027	biological_process	ribosomal large subunit assembly
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0019843	molecular_function	rRNA binding
Q	0022625	cellular_component	cytosolic large ribosomal subunit
Q	1990904	cellular_component	ribonucleoprotein complex
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005737	cellular_component	cytoplasm
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0019843	molecular_function	rRNA binding
R	1990904	cellular_component	ribonucleoprotein complex
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015934	cellular_component	large ribosomal subunit
S	0019843	molecular_function	rRNA binding
S	0022625	cellular_component	cytosolic large ribosomal subunit
S	1990904	cellular_component	ribonucleoprotein complex
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0019843	molecular_function	rRNA binding
T	0022625	cellular_component	cytosolic large ribosomal subunit
T	1990904	cellular_component	ribonucleoprotein complex
U	0003677	molecular_function	DNA binding
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005737	cellular_component	cytoplasm
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0009295	cellular_component	nucleoid
U	0019843	molecular_function	rRNA binding
U	0022625	cellular_component	cytosolic large ribosomal subunit
U	1990904	cellular_component	ribonucleoprotein complex
V	0000049	molecular_function	tRNA binding
V	0003723	molecular_function	RNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005737	cellular_component	cytoplasm
V	0006412	biological_process	translation
V	0015935	cellular_component	small ribosomal subunit
V	0019843	molecular_function	rRNA binding
V	0042254	biological_process	ribosome biogenesis
V	0042274	biological_process	ribosomal small subunit biogenesis
V	0043023	molecular_function	ribosomal large subunit binding
V	0072344	biological_process	rescue of stalled ribosome
V	1990112	cellular_component	RQC complex
W	0003735	molecular_function	structural constituent of ribosome
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0022625	cellular_component	cytosolic large ribosomal subunit
W	1990904	cellular_component	ribonucleoprotein complex
X	0003735	molecular_function	structural constituent of ribosome
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	1990904	cellular_component	ribonucleoprotein complex
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0022625	cellular_component	cytosolic large ribosomal subunit
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
Z	0015934	cellular_component	large ribosomal subunit
Z	0022625	cellular_component	cytosolic large ribosomal subunit
Z	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVIVrtksgarrs.DGsyisFdeNacVI

Chain	Residue	Details
K	ALA60-ILE86

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. RKAIVKLTadskeieI

Chain	Residue	Details
T	ARG77-ILE92

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LtfIAGQkpVvTrAKkS

Chain	Residue	Details
F	LEU57-SER73

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. KrfRpRAmGRasqinkrtSHITIvV

Chain	Residue	Details
S	LYS83-VAL107

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGSVmNPnD

Chain	Residue	Details
C	PRO218-ASP229

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FsageivDvtGvSkGKGfqGaikR

Chain	Residue	Details
D	PHE102-ARG125

site_id	PS00475
Number of Residues	31
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KILGnGkLekk..LtVkankFSasAkeaVeaaG

Chain	Residue	Details
L	LYS110-GLY140

site_id	PS00525
Number of Residues	9
Details	RIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PEpYKGKGI

Chain	Residue	Details
G	PRO155-ILE163

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. NTARIReVRKAIARM

Chain	Residue	Details
Y	ASN39-MET53

site_id	PS00582
Number of Residues	20
Details	RIBOSOMAL_L33 Ribosomal protein L33 signature. YiSkKNkrnnPdrVEfkKYC

Chain	Residue	Details
1	TYR17-CYS36

site_id	PS00586
Number of Residues	12
Details	RIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRgGKVWIKIFP

Chain	Residue	Details
M	LYS59-PRO70

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. TVrtLgLkKtnQtVvhednaairgMInkVshLV

Chain	Residue	Details
Z	THR22-VAL54

site_id	PS00701
Number of Residues	12
Details	RIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGsGKGapegW

Chain	Residue	Details
M	ARG82-TRP93

site_id	PS00783
Number of Residues	23
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. IKGMLPkgsl.GRqmfkkLnVYrG

Chain	Residue	Details
J	ILE106-GLY128

site_id	PS00784
Number of Residues	20
Details	RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTFQpnnrkRskvh.GFrsR

Chain	Residue	Details
2	LYS2-ARG21

site_id	PS00828
Number of Residues	26
Details	RIBOSOMAL_L36 Ribosomal protein L36 signature. CekCkvIrRkgkVmViCenp.KHkQkQ

Chain	Residue	Details
4	CYS11-GLN36

site_id	PS00831
Number of Residues	15
Details	RIBOSOMAL_L27 Ribosomal protein L27 signature. GsILyRQRGtkiypG

Chain	Residue	Details
W	GLY42-GLY56

site_id	PS00936
Number of Residues	27
Details	RIBOSOMAL_L35 Ribosomal protein L35 signature. KTHrGSaKRFkktgsgklkrshayt.SH

Chain	Residue	Details
3	LYS5-HIS31

site_id	PS00937
Number of Residues	17
Details	RIBOSOMAL_L20 Ribosomal protein L20 signature. KrdfRkLWITRINaaaR

Chain	Residue	Details
Q	LYS54-ARG70

site_id	PS01015
Number of Residues	16
Details	RIBOSOMAL_L19 Ribosomal protein L19 signature. VvRyGKVR.RAKLYYLR

Chain	Residue	Details
P	VAL86-ARG101

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. GDkVmVIsGkdKGkq.GtI

Chain	Residue	Details
U	GLY6-ILE23

site_id	PS01143
Number of Residues	22
Details	RIBOSOMAL_L31 Ribosomal protein L31 signature. EIcsecHPFYTgrqkfasad....GR

Chain	Residue	Details
6	GLU34-ARG55

site_id	PS01167
Number of Residues	23
Details	RIBOSOMAL_L17 Ribosomal protein L17 signature. IeTTetRaKelrsvvEkMITlGK

Chain	Residue	Details
N	ILE30-LYS52

site_id	PS01169
Number of Residues	23
Details	RIBOSOMAL_L21 Ribosomal protein L21 signature. ItvfRykpKKnvhkkqGHRQpyT

Chain	Residue	Details
R	ILE71-THR93

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	178
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	36
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	29
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	20
Details	Compositional bias: {"description":"Gly residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	70
Details	Domain: {"description":"S4 RNA-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00182","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"38811035","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	79
Details	Region: {"description":"Central region","evidences":[{"source":"PubMed","id":"38811035","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	172
Details	Region: {"description":"NFACT-N domain","evidences":[{"source":"PubMed","id":"33259810","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33259811","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34255840","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	102
Details	Region: {"description":"HhH domain","evidences":[{"source":"PubMed","id":"33259810","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33259811","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34255840","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	57
Details	Coiled coil: {"evidences":[{"source":"PubMed","id":"33259810","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33259811","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34255840","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7AQC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7AQD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7AS8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7AS9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ASA","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)