8S0M
Crystal structure of the HKU1 receptor binding domain in complex with TMPRSS2 and the nanobody A01
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAAHC |
| Chain | Residue | Details |
| B | VAL292-CYS297 |
| site_id | PS01209 |
| Number of Residues | 23 |
| Details | LDLRA_1 LDL-receptor class A (LDLRA) domain signature. CInpsnw.CDgvsHCpgg.EDEnr...C |
| Chain | Residue | Details |
| B | CYS126-CYS148 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099 |
| Chain | Residue | Details |
| A | ASN29 | |
| D | ASN148 | |
| D | ASN255 | |
| D | ASN358 | |
| A | ASN49 | |
| A | ASN127 | |
| A | ASN148 | |
| A | ASN255 | |
| A | ASN358 | |
| D | ASN29 | |
| D | ASN49 | |
| D | ASN127 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| B | ALA441 | |
| E | ALA441 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Cleavage => ECO:0000269|PubMed:11245484 |
| Chain | Residue | Details |
| B | ARG255 | |
| E | ARG255 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| B | ASN213 | |
| B | ASN249 | |
| E | ASN213 | |
| E | ASN249 |
