8RTD

Stalk-Arches-IMC structure from the fully-assembled R388 type IV secretion system determined by cryo-EM.

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0005515	molecular_function	protein binding
a	0005886	cellular_component	plasma membrane
a	0009279	cellular_component	cell outer membrane
b	0005515	molecular_function	protein binding
b	0005886	cellular_component	plasma membrane
b	0016020	cellular_component	membrane
c	0005515	molecular_function	protein binding
c	0005886	cellular_component	plasma membrane
c	0016020	cellular_component	membrane
d	0005515	molecular_function	protein binding
d	0005886	cellular_component	plasma membrane
d	0016020	cellular_component	membrane
D	0005515	molecular_function	protein binding
D	0005886	cellular_component	plasma membrane
D	0016020	cellular_component	membrane
e	0005515	molecular_function	protein binding
e	0005886	cellular_component	plasma membrane
e	0009279	cellular_component	cell outer membrane
f	0005515	molecular_function	protein binding
f	0005886	cellular_component	plasma membrane
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0016020	cellular_component	membrane
g	0005515	molecular_function	protein binding
g	0005524	molecular_function	ATP binding
g	0005886	cellular_component	plasma membrane
g	0016887	molecular_function	ATP hydrolysis activity
G	0005515	molecular_function	protein binding
G	0005886	cellular_component	plasma membrane
G	0016020	cellular_component	membrane
h	0005515	molecular_function	protein binding
h	0005524	molecular_function	ATP binding
h	0005886	cellular_component	plasma membrane
h	0016887	molecular_function	ATP hydrolysis activity
H	0005515	molecular_function	protein binding
H	0005886	cellular_component	plasma membrane
H	0030255	biological_process	protein secretion by the type IV secretion system
i	0005515	molecular_function	protein binding
i	0005886	cellular_component	plasma membrane
i	0016020	cellular_component	membrane
I	0005515	molecular_function	protein binding
I	0005886	cellular_component	plasma membrane
I	0030255	biological_process	protein secretion by the type IV secretion system
j	0005515	molecular_function	protein binding
j	0005886	cellular_component	plasma membrane
J	0005515	molecular_function	protein binding
J	0005886	cellular_component	plasma membrane
J	0030255	biological_process	protein secretion by the type IV secretion system
L	0005515	molecular_function	protein binding
L	0005886	cellular_component	plasma membrane
L	0030255	biological_process	protein secretion by the type IV secretion system
M	0005515	molecular_function	protein binding
M	0005886	cellular_component	plasma membrane
M	0030255	biological_process	protein secretion by the type IV secretion system
O	0005515	molecular_function	protein binding
O	0005524	molecular_function	ATP binding
O	0005886	cellular_component	plasma membrane
O	0016887	molecular_function	ATP hydrolysis activity
P	0005515	molecular_function	protein binding
P	0005524	molecular_function	ATP binding
P	0005886	cellular_component	plasma membrane
P	0016887	molecular_function	ATP hydrolysis activity
Q	0005515	molecular_function	protein binding
Q	0005886	cellular_component	plasma membrane
Q	0016020	cellular_component	membrane
R	0005515	molecular_function	protein binding
R	0005886	cellular_component	plasma membrane
S	0005515	molecular_function	protein binding
S	0005886	cellular_component	plasma membrane
S	0016020	cellular_component	membrane
T	0005515	molecular_function	protein binding
T	0005524	molecular_function	ATP binding
T	0005886	cellular_component	plasma membrane
T	0016887	molecular_function	ATP hydrolysis activity
U	0005515	molecular_function	protein binding
U	0005886	cellular_component	plasma membrane
U	0016020	cellular_component	membrane
V	0005515	molecular_function	protein binding
V	0005524	molecular_function	ATP binding
V	0005886	cellular_component	plasma membrane
V	0016887	molecular_function	ATP hydrolysis activity
X	0005515	molecular_function	protein binding
X	0005886	cellular_component	plasma membrane
X	0016020	cellular_component	membrane
Y	0005515	molecular_function	protein binding
Y	0005886	cellular_component	plasma membrane
Y	0016020	cellular_component	membrane
Z	0005515	molecular_function	protein binding
Z	0005886	cellular_component	plasma membrane
Z	0009279	cellular_component	cell outer membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI4
Number of Residues	92
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"35732732","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	52
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"38886579","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	108
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"35732732","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38886579","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	18
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	78
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"35732732","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7OIU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	193
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"35732732","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	132
Details	Transmembrane: {"evidences":[{"source":"PubMed","id":"35732732","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7OIU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	42
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	72
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"35732732","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---