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8RRO

G12V-TCR complex with HLA-A3

Functional Information from GO Data
ChainGOidnamespacecontents
D0000139cellular_componentGolgi membrane
D0001913biological_processT cell mediated cytotoxicity
D0001916biological_processpositive regulation of T cell mediated cytotoxicity
D0002237biological_processresponse to molecule of bacterial origin
D0002376biological_processimmune system process
D0002474biological_processantigen processing and presentation of peptide antigen via MHC class I
D0002481biological_processantigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
D0002502biological_processpeptide antigen assembly with MHC class I protein complex
D0002503biological_processpeptide antigen assembly with MHC class II protein complex
D0002726biological_processpositive regulation of T cell cytokine production
D0005198molecular_functionstructural molecule activity
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005765cellular_componentlysosomal membrane
D0005783cellular_componentendoplasmic reticulum
D0005788cellular_componentendoplasmic reticulum lumen
D0005794cellular_componentGolgi apparatus
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0005925cellular_componentfocal adhesion
D0006826biological_processiron ion transport
D0006879biological_processintracellular iron ion homeostasis
D0006955biological_processimmune response
D0007608biological_processsensory perception of smell
D0007611biological_processlearning or memory
D0009897cellular_componentexternal side of plasma membrane
D0009986cellular_componentcell surface
D0010038biological_processresponse to metal ion
D0010977biological_processnegative regulation of neuron projection development
D0012507cellular_componentER to Golgi transport vesicle membrane
D0016020cellular_componentmembrane
D0019885biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I
D0019886biological_processantigen processing and presentation of exogenous peptide antigen via MHC class II
D0023026molecular_functionMHC class II protein complex binding
D0030670cellular_componentphagocytic vesicle membrane
D0031901cellular_componentearly endosome membrane
D0031902cellular_componentlate endosome membrane
D0031905cellular_componentearly endosome lumen
D0033077biological_processT cell differentiation in thymus
D0033572biological_processtransferrin transport
D0034756biological_processregulation of iron ion transport
D0034757biological_processnegative regulation of iron ion transport
D0035580cellular_componentspecific granule lumen
D0042026biological_processprotein refolding
D0042605molecular_functionpeptide antigen binding
D0042612cellular_componentMHC class I protein complex
D0042613cellular_componentMHC class II protein complex
D0042802molecular_functionidentical protein binding
D0042803molecular_functionprotein homodimerization activity
D0042824cellular_componentMHC class I peptide loading complex
D0045646biological_processregulation of erythrocyte differentiation
D0048260biological_processpositive regulation of receptor-mediated endocytosis
D0048261biological_processnegative regulation of receptor-mediated endocytosis
D0050680biological_processnegative regulation of epithelial cell proliferation
D0050768biological_processnegative regulation of neurogenesis
D0050778biological_processpositive regulation of immune response
D0050870biological_processpositive regulation of T cell activation
D0051289biological_processprotein homotetramerization
D0055038cellular_componentrecycling endosome membrane
D0060586biological_processmulticellular organismal-level iron ion homeostasis
D0070062cellular_componentextracellular exosome
D0071281biological_processcellular response to iron ion
D0071283biological_processcellular response to iron(III) ion
D0071316biological_processcellular response to nicotine
D1904724cellular_componenttertiary granule lumen
D1990000biological_processamyloid fibril formation
D1990712cellular_componentHFE-transferrin receptor complex
D2000774biological_processpositive regulation of cellular senescence
D2000978biological_processnegative regulation of forebrain neuron differentiation
I0000139cellular_componentGolgi membrane
I0001913biological_processT cell mediated cytotoxicity
I0001916biological_processpositive regulation of T cell mediated cytotoxicity
I0002237biological_processresponse to molecule of bacterial origin
I0002376biological_processimmune system process
I0002474biological_processantigen processing and presentation of peptide antigen via MHC class I
I0002481biological_processantigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
I0002502biological_processpeptide antigen assembly with MHC class I protein complex
I0002503biological_processpeptide antigen assembly with MHC class II protein complex
I0002726biological_processpositive regulation of T cell cytokine production
I0005198molecular_functionstructural molecule activity
I0005515molecular_functionprotein binding
I0005576cellular_componentextracellular region
I0005615cellular_componentextracellular space
I0005765cellular_componentlysosomal membrane
I0005783cellular_componentendoplasmic reticulum
I0005788cellular_componentendoplasmic reticulum lumen
I0005794cellular_componentGolgi apparatus
I0005829cellular_componentcytosol
I0005886cellular_componentplasma membrane
I0005925cellular_componentfocal adhesion
I0006826biological_processiron ion transport
I0006879biological_processintracellular iron ion homeostasis
I0006955biological_processimmune response
I0007608biological_processsensory perception of smell
I0007611biological_processlearning or memory
I0009897cellular_componentexternal side of plasma membrane
I0009986cellular_componentcell surface
I0010038biological_processresponse to metal ion
I0010977biological_processnegative regulation of neuron projection development
I0012507cellular_componentER to Golgi transport vesicle membrane
I0016020cellular_componentmembrane
I0019885biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I
I0019886biological_processantigen processing and presentation of exogenous peptide antigen via MHC class II
I0023026molecular_functionMHC class II protein complex binding
I0030670cellular_componentphagocytic vesicle membrane
I0031901cellular_componentearly endosome membrane
I0031902cellular_componentlate endosome membrane
I0031905cellular_componentearly endosome lumen
I0033077biological_processT cell differentiation in thymus
I0033572biological_processtransferrin transport
I0034756biological_processregulation of iron ion transport
I0034757biological_processnegative regulation of iron ion transport
I0035580cellular_componentspecific granule lumen
I0042026biological_processprotein refolding
I0042605molecular_functionpeptide antigen binding
I0042612cellular_componentMHC class I protein complex
I0042613cellular_componentMHC class II protein complex
I0042802molecular_functionidentical protein binding
I0042803molecular_functionprotein homodimerization activity
I0042824cellular_componentMHC class I peptide loading complex
I0045646biological_processregulation of erythrocyte differentiation
I0048260biological_processpositive regulation of receptor-mediated endocytosis
I0048261biological_processnegative regulation of receptor-mediated endocytosis
I0050680biological_processnegative regulation of epithelial cell proliferation
I0050768biological_processnegative regulation of neurogenesis
I0050778biological_processpositive regulation of immune response
I0050870biological_processpositive regulation of T cell activation
I0051289biological_processprotein homotetramerization
I0055038cellular_componentrecycling endosome membrane
I0060586biological_processmulticellular organismal-level iron ion homeostasis
I0070062cellular_componentextracellular exosome
I0071281biological_processcellular response to iron ion
I0071283biological_processcellular response to iron(III) ion
I0071316biological_processcellular response to nicotine
I1904724cellular_componenttertiary granule lumen
I1990000biological_processamyloid fibril formation
I1990712cellular_componentHFE-transferrin receptor complex
I2000774biological_processpositive regulation of cellular senescence
I2000978biological_processnegative regulation of forebrain neuron differentiation
N0000139cellular_componentGolgi membrane
N0001913biological_processT cell mediated cytotoxicity
N0001916biological_processpositive regulation of T cell mediated cytotoxicity
N0002237biological_processresponse to molecule of bacterial origin
N0002376biological_processimmune system process
N0002474biological_processantigen processing and presentation of peptide antigen via MHC class I
N0002481biological_processantigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
N0002502biological_processpeptide antigen assembly with MHC class I protein complex
N0002503biological_processpeptide antigen assembly with MHC class II protein complex
N0002726biological_processpositive regulation of T cell cytokine production
N0005198molecular_functionstructural molecule activity
N0005515molecular_functionprotein binding
N0005576cellular_componentextracellular region
N0005615cellular_componentextracellular space
N0005765cellular_componentlysosomal membrane
N0005783cellular_componentendoplasmic reticulum
N0005788cellular_componentendoplasmic reticulum lumen
N0005794cellular_componentGolgi apparatus
N0005829cellular_componentcytosol
N0005886cellular_componentplasma membrane
N0005925cellular_componentfocal adhesion
N0006826biological_processiron ion transport
N0006879biological_processintracellular iron ion homeostasis
N0006955biological_processimmune response
N0007608biological_processsensory perception of smell
N0007611biological_processlearning or memory
N0009897cellular_componentexternal side of plasma membrane
N0009986cellular_componentcell surface
N0010038biological_processresponse to metal ion
N0010977biological_processnegative regulation of neuron projection development
N0012507cellular_componentER to Golgi transport vesicle membrane
N0016020cellular_componentmembrane
N0019885biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I
N0019886biological_processantigen processing and presentation of exogenous peptide antigen via MHC class II
N0023026molecular_functionMHC class II protein complex binding
N0030670cellular_componentphagocytic vesicle membrane
N0031901cellular_componentearly endosome membrane
N0031902cellular_componentlate endosome membrane
N0031905cellular_componentearly endosome lumen
N0033077biological_processT cell differentiation in thymus
N0033572biological_processtransferrin transport
N0034756biological_processregulation of iron ion transport
N0034757biological_processnegative regulation of iron ion transport
N0035580cellular_componentspecific granule lumen
N0042026biological_processprotein refolding
N0042605molecular_functionpeptide antigen binding
N0042612cellular_componentMHC class I protein complex
N0042613cellular_componentMHC class II protein complex
N0042802molecular_functionidentical protein binding
N0042803molecular_functionprotein homodimerization activity
N0042824cellular_componentMHC class I peptide loading complex
N0045646biological_processregulation of erythrocyte differentiation
N0048260biological_processpositive regulation of receptor-mediated endocytosis
N0048261biological_processnegative regulation of receptor-mediated endocytosis
N0050680biological_processnegative regulation of epithelial cell proliferation
N0050768biological_processnegative regulation of neurogenesis
N0050778biological_processpositive regulation of immune response
N0050870biological_processpositive regulation of T cell activation
N0051289biological_processprotein homotetramerization
N0055038cellular_componentrecycling endosome membrane
N0060586biological_processmulticellular organismal-level iron ion homeostasis
N0070062cellular_componentextracellular exosome
N0071281biological_processcellular response to iron ion
N0071283biological_processcellular response to iron(III) ion
N0071316biological_processcellular response to nicotine
N1904724cellular_componenttertiary granule lumen
N1990000biological_processamyloid fibril formation
N1990712cellular_componentHFE-transferrin receptor complex
N2000774biological_processpositive regulation of cellular senescence
N2000978biological_processnegative regulation of forebrain neuron differentiation
S0000139cellular_componentGolgi membrane
S0001913biological_processT cell mediated cytotoxicity
S0001916biological_processpositive regulation of T cell mediated cytotoxicity
S0002237biological_processresponse to molecule of bacterial origin
S0002376biological_processimmune system process
S0002474biological_processantigen processing and presentation of peptide antigen via MHC class I
S0002481biological_processantigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
S0002502biological_processpeptide antigen assembly with MHC class I protein complex
S0002503biological_processpeptide antigen assembly with MHC class II protein complex
S0002726biological_processpositive regulation of T cell cytokine production
S0005198molecular_functionstructural molecule activity
S0005515molecular_functionprotein binding
S0005576cellular_componentextracellular region
S0005615cellular_componentextracellular space
S0005765cellular_componentlysosomal membrane
S0005783cellular_componentendoplasmic reticulum
S0005788cellular_componentendoplasmic reticulum lumen
S0005794cellular_componentGolgi apparatus
S0005829cellular_componentcytosol
S0005886cellular_componentplasma membrane
S0005925cellular_componentfocal adhesion
S0006826biological_processiron ion transport
S0006879biological_processintracellular iron ion homeostasis
S0006955biological_processimmune response
S0007608biological_processsensory perception of smell
S0007611biological_processlearning or memory
S0009897cellular_componentexternal side of plasma membrane
S0009986cellular_componentcell surface
S0010038biological_processresponse to metal ion
S0010977biological_processnegative regulation of neuron projection development
S0012507cellular_componentER to Golgi transport vesicle membrane
S0016020cellular_componentmembrane
S0019885biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I
S0019886biological_processantigen processing and presentation of exogenous peptide antigen via MHC class II
S0023026molecular_functionMHC class II protein complex binding
S0030670cellular_componentphagocytic vesicle membrane
S0031901cellular_componentearly endosome membrane
S0031902cellular_componentlate endosome membrane
S0031905cellular_componentearly endosome lumen
S0033077biological_processT cell differentiation in thymus
S0033572biological_processtransferrin transport
S0034756biological_processregulation of iron ion transport
S0034757biological_processnegative regulation of iron ion transport
S0035580cellular_componentspecific granule lumen
S0042026biological_processprotein refolding
S0042605molecular_functionpeptide antigen binding
S0042612cellular_componentMHC class I protein complex
S0042613cellular_componentMHC class II protein complex
S0042802molecular_functionidentical protein binding
S0042803molecular_functionprotein homodimerization activity
S0042824cellular_componentMHC class I peptide loading complex
S0045646biological_processregulation of erythrocyte differentiation
S0048260biological_processpositive regulation of receptor-mediated endocytosis
S0048261biological_processnegative regulation of receptor-mediated endocytosis
S0050680biological_processnegative regulation of epithelial cell proliferation
S0050768biological_processnegative regulation of neurogenesis
S0050778biological_processpositive regulation of immune response
S0050870biological_processpositive regulation of T cell activation
S0051289biological_processprotein homotetramerization
S0055038cellular_componentrecycling endosome membrane
S0060586biological_processmulticellular organismal-level iron ion homeostasis
S0070062cellular_componentextracellular exosome
S0071281biological_processcellular response to iron ion
S0071283biological_processcellular response to iron(III) ion
S0071316biological_processcellular response to nicotine
S1904724cellular_componenttertiary granule lumen
S1990000biological_processamyloid fibril formation
S1990712cellular_componentHFE-transferrin receptor complex
S2000774biological_processpositive regulation of cellular senescence
S2000978biological_processnegative regulation of forebrain neuron differentiation
X0000139cellular_componentGolgi membrane
X0001913biological_processT cell mediated cytotoxicity
X0001916biological_processpositive regulation of T cell mediated cytotoxicity
X0002237biological_processresponse to molecule of bacterial origin
X0002376biological_processimmune system process
X0002474biological_processantigen processing and presentation of peptide antigen via MHC class I
X0002481biological_processantigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
X0002502biological_processpeptide antigen assembly with MHC class I protein complex
X0002503biological_processpeptide antigen assembly with MHC class II protein complex
X0002726biological_processpositive regulation of T cell cytokine production
X0005198molecular_functionstructural molecule activity
X0005515molecular_functionprotein binding
X0005576cellular_componentextracellular region
X0005615cellular_componentextracellular space
X0005765cellular_componentlysosomal membrane
X0005783cellular_componentendoplasmic reticulum
X0005788cellular_componentendoplasmic reticulum lumen
X0005794cellular_componentGolgi apparatus
X0005829cellular_componentcytosol
X0005886cellular_componentplasma membrane
X0005925cellular_componentfocal adhesion
X0006826biological_processiron ion transport
X0006879biological_processintracellular iron ion homeostasis
X0006955biological_processimmune response
X0007608biological_processsensory perception of smell
X0007611biological_processlearning or memory
X0009897cellular_componentexternal side of plasma membrane
X0009986cellular_componentcell surface
X0010038biological_processresponse to metal ion
X0010977biological_processnegative regulation of neuron projection development
X0012507cellular_componentER to Golgi transport vesicle membrane
X0016020cellular_componentmembrane
X0019885biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I
X0019886biological_processantigen processing and presentation of exogenous peptide antigen via MHC class II
X0023026molecular_functionMHC class II protein complex binding
X0030670cellular_componentphagocytic vesicle membrane
X0031901cellular_componentearly endosome membrane
X0031902cellular_componentlate endosome membrane
X0031905cellular_componentearly endosome lumen
X0033077biological_processT cell differentiation in thymus
X0033572biological_processtransferrin transport
X0034756biological_processregulation of iron ion transport
X0034757biological_processnegative regulation of iron ion transport
X0035580cellular_componentspecific granule lumen
X0042026biological_processprotein refolding
X0042605molecular_functionpeptide antigen binding
X0042612cellular_componentMHC class I protein complex
X0042613cellular_componentMHC class II protein complex
X0042802molecular_functionidentical protein binding
X0042803molecular_functionprotein homodimerization activity
X0042824cellular_componentMHC class I peptide loading complex
X0045646biological_processregulation of erythrocyte differentiation
X0048260biological_processpositive regulation of receptor-mediated endocytosis
X0048261biological_processnegative regulation of receptor-mediated endocytosis
X0050680biological_processnegative regulation of epithelial cell proliferation
X0050768biological_processnegative regulation of neurogenesis
X0050778biological_processpositive regulation of immune response
X0050870biological_processpositive regulation of T cell activation
X0051289biological_processprotein homotetramerization
X0055038cellular_componentrecycling endosome membrane
X0060586biological_processmulticellular organismal-level iron ion homeostasis
X0070062cellular_componentextracellular exosome
X0071281biological_processcellular response to iron ion
X0071283biological_processcellular response to iron(III) ion
X0071316biological_processcellular response to nicotine
X1904724cellular_componenttertiary granule lumen
X1990000biological_processamyloid fibril formation
X1990712cellular_componentHFE-transferrin receptor complex
X2000774biological_processpositive regulation of cellular senescence
X2000978biological_processnegative regulation of forebrain neuron differentiation
c0000139cellular_componentGolgi membrane
c0001913biological_processT cell mediated cytotoxicity
c0001916biological_processpositive regulation of T cell mediated cytotoxicity
c0002237biological_processresponse to molecule of bacterial origin
c0002376biological_processimmune system process
c0002474biological_processantigen processing and presentation of peptide antigen via MHC class I
c0002481biological_processantigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
c0002502biological_processpeptide antigen assembly with MHC class I protein complex
c0002503biological_processpeptide antigen assembly with MHC class II protein complex
c0002726biological_processpositive regulation of T cell cytokine production
c0005198molecular_functionstructural molecule activity
c0005515molecular_functionprotein binding
c0005576cellular_componentextracellular region
c0005615cellular_componentextracellular space
c0005765cellular_componentlysosomal membrane
c0005783cellular_componentendoplasmic reticulum
c0005788cellular_componentendoplasmic reticulum lumen
c0005794cellular_componentGolgi apparatus
c0005829cellular_componentcytosol
c0005886cellular_componentplasma membrane
c0005925cellular_componentfocal adhesion
c0006826biological_processiron ion transport
c0006879biological_processintracellular iron ion homeostasis
c0006955biological_processimmune response
c0007608biological_processsensory perception of smell
c0007611biological_processlearning or memory
c0009897cellular_componentexternal side of plasma membrane
c0009986cellular_componentcell surface
c0010038biological_processresponse to metal ion
c0010977biological_processnegative regulation of neuron projection development
c0012507cellular_componentER to Golgi transport vesicle membrane
c0016020cellular_componentmembrane
c0019885biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I
c0019886biological_processantigen processing and presentation of exogenous peptide antigen via MHC class II
c0023026molecular_functionMHC class II protein complex binding
c0030670cellular_componentphagocytic vesicle membrane
c0031901cellular_componentearly endosome membrane
c0031902cellular_componentlate endosome membrane
c0031905cellular_componentearly endosome lumen
c0033077biological_processT cell differentiation in thymus
c0033572biological_processtransferrin transport
c0034756biological_processregulation of iron ion transport
c0034757biological_processnegative regulation of iron ion transport
c0035580cellular_componentspecific granule lumen
c0042026biological_processprotein refolding
c0042605molecular_functionpeptide antigen binding
c0042612cellular_componentMHC class I protein complex
c0042613cellular_componentMHC class II protein complex
c0042802molecular_functionidentical protein binding
c0042803molecular_functionprotein homodimerization activity
c0042824cellular_componentMHC class I peptide loading complex
c0045646biological_processregulation of erythrocyte differentiation
c0048260biological_processpositive regulation of receptor-mediated endocytosis
c0048261biological_processnegative regulation of receptor-mediated endocytosis
c0050680biological_processnegative regulation of epithelial cell proliferation
c0050768biological_processnegative regulation of neurogenesis
c0050778biological_processpositive regulation of immune response
c0050870biological_processpositive regulation of T cell activation
c0051289biological_processprotein homotetramerization
c0055038cellular_componentrecycling endosome membrane
c0060586biological_processmulticellular organismal-level iron ion homeostasis
c0070062cellular_componentextracellular exosome
c0071281biological_processcellular response to iron ion
c0071283biological_processcellular response to iron(III) ion
c0071316biological_processcellular response to nicotine
c1904724cellular_componenttertiary granule lumen
c1990000biological_processamyloid fibril formation
c1990712cellular_componentHFE-transferrin receptor complex
c2000774biological_processpositive regulation of cellular senescence
c2000978biological_processnegative regulation of forebrain neuron differentiation
h0000139cellular_componentGolgi membrane
h0001913biological_processT cell mediated cytotoxicity
h0001916biological_processpositive regulation of T cell mediated cytotoxicity
h0002237biological_processresponse to molecule of bacterial origin
h0002376biological_processimmune system process
h0002474biological_processantigen processing and presentation of peptide antigen via MHC class I
h0002481biological_processantigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
h0002502biological_processpeptide antigen assembly with MHC class I protein complex
h0002503biological_processpeptide antigen assembly with MHC class II protein complex
h0002726biological_processpositive regulation of T cell cytokine production
h0005198molecular_functionstructural molecule activity
h0005515molecular_functionprotein binding
h0005576cellular_componentextracellular region
h0005615cellular_componentextracellular space
h0005765cellular_componentlysosomal membrane
h0005783cellular_componentendoplasmic reticulum
h0005788cellular_componentendoplasmic reticulum lumen
h0005794cellular_componentGolgi apparatus
h0005829cellular_componentcytosol
h0005886cellular_componentplasma membrane
h0005925cellular_componentfocal adhesion
h0006826biological_processiron ion transport
h0006879biological_processintracellular iron ion homeostasis
h0006955biological_processimmune response
h0007608biological_processsensory perception of smell
h0007611biological_processlearning or memory
h0009897cellular_componentexternal side of plasma membrane
h0009986cellular_componentcell surface
h0010038biological_processresponse to metal ion
h0010977biological_processnegative regulation of neuron projection development
h0012507cellular_componentER to Golgi transport vesicle membrane
h0016020cellular_componentmembrane
h0019885biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I
h0019886biological_processantigen processing and presentation of exogenous peptide antigen via MHC class II
h0023026molecular_functionMHC class II protein complex binding
h0030670cellular_componentphagocytic vesicle membrane
h0031901cellular_componentearly endosome membrane
h0031902cellular_componentlate endosome membrane
h0031905cellular_componentearly endosome lumen
h0033077biological_processT cell differentiation in thymus
h0033572biological_processtransferrin transport
h0034756biological_processregulation of iron ion transport
h0034757biological_processnegative regulation of iron ion transport
h0035580cellular_componentspecific granule lumen
h0042026biological_processprotein refolding
h0042605molecular_functionpeptide antigen binding
h0042612cellular_componentMHC class I protein complex
h0042613cellular_componentMHC class II protein complex
h0042802molecular_functionidentical protein binding
h0042803molecular_functionprotein homodimerization activity
h0042824cellular_componentMHC class I peptide loading complex
h0045646biological_processregulation of erythrocyte differentiation
h0048260biological_processpositive regulation of receptor-mediated endocytosis
h0048261biological_processnegative regulation of receptor-mediated endocytosis
h0050680biological_processnegative regulation of epithelial cell proliferation
h0050768biological_processnegative regulation of neurogenesis
h0050778biological_processpositive regulation of immune response
h0050870biological_processpositive regulation of T cell activation
h0051289biological_processprotein homotetramerization
h0055038cellular_componentrecycling endosome membrane
h0060586biological_processmulticellular organismal-level iron ion homeostasis
h0070062cellular_componentextracellular exosome
h0071281biological_processcellular response to iron ion
h0071283biological_processcellular response to iron(III) ion
h0071316biological_processcellular response to nicotine
h1904724cellular_componenttertiary granule lumen
h1990000biological_processamyloid fibril formation
h1990712cellular_componentHFE-transferrin receptor complex
h2000774biological_processpositive regulation of cellular senescence
h2000978biological_processnegative regulation of forebrain neuron differentiation
m0000139cellular_componentGolgi membrane
m0001913biological_processT cell mediated cytotoxicity
m0001916biological_processpositive regulation of T cell mediated cytotoxicity
m0002237biological_processresponse to molecule of bacterial origin
m0002376biological_processimmune system process
m0002474biological_processantigen processing and presentation of peptide antigen via MHC class I
m0002481biological_processantigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
m0002502biological_processpeptide antigen assembly with MHC class I protein complex
m0002503biological_processpeptide antigen assembly with MHC class II protein complex
m0002726biological_processpositive regulation of T cell cytokine production
m0005198molecular_functionstructural molecule activity
m0005515molecular_functionprotein binding
m0005576cellular_componentextracellular region
m0005615cellular_componentextracellular space
m0005765cellular_componentlysosomal membrane
m0005783cellular_componentendoplasmic reticulum
m0005788cellular_componentendoplasmic reticulum lumen
m0005794cellular_componentGolgi apparatus
m0005829cellular_componentcytosol
m0005886cellular_componentplasma membrane
m0005925cellular_componentfocal adhesion
m0006826biological_processiron ion transport
m0006879biological_processintracellular iron ion homeostasis
m0006955biological_processimmune response
m0007608biological_processsensory perception of smell
m0007611biological_processlearning or memory
m0009897cellular_componentexternal side of plasma membrane
m0009986cellular_componentcell surface
m0010038biological_processresponse to metal ion
m0010977biological_processnegative regulation of neuron projection development
m0012507cellular_componentER to Golgi transport vesicle membrane
m0016020cellular_componentmembrane
m0019885biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I
m0019886biological_processantigen processing and presentation of exogenous peptide antigen via MHC class II
m0023026molecular_functionMHC class II protein complex binding
m0030670cellular_componentphagocytic vesicle membrane
m0031901cellular_componentearly endosome membrane
m0031902cellular_componentlate endosome membrane
m0031905cellular_componentearly endosome lumen
m0033077biological_processT cell differentiation in thymus
m0033572biological_processtransferrin transport
m0034756biological_processregulation of iron ion transport
m0034757biological_processnegative regulation of iron ion transport
m0035580cellular_componentspecific granule lumen
m0042026biological_processprotein refolding
m0042605molecular_functionpeptide antigen binding
m0042612cellular_componentMHC class I protein complex
m0042613cellular_componentMHC class II protein complex
m0042802molecular_functionidentical protein binding
m0042803molecular_functionprotein homodimerization activity
m0042824cellular_componentMHC class I peptide loading complex
m0045646biological_processregulation of erythrocyte differentiation
m0048260biological_processpositive regulation of receptor-mediated endocytosis
m0048261biological_processnegative regulation of receptor-mediated endocytosis
m0050680biological_processnegative regulation of epithelial cell proliferation
m0050768biological_processnegative regulation of neurogenesis
m0050778biological_processpositive regulation of immune response
m0050870biological_processpositive regulation of T cell activation
m0051289biological_processprotein homotetramerization
m0055038cellular_componentrecycling endosome membrane
m0060586biological_processmulticellular organismal-level iron ion homeostasis
m0070062cellular_componentextracellular exosome
m0071281biological_processcellular response to iron ion
m0071283biological_processcellular response to iron(III) ion
m0071316biological_processcellular response to nicotine
m1904724cellular_componenttertiary granule lumen
m1990000biological_processamyloid fibril formation
m1990712cellular_componentHFE-transferrin receptor complex
m2000774biological_processpositive regulation of cellular senescence
m2000978biological_processnegative regulation of forebrain neuron differentiation
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH
ChainResidueDetails
cTYR78-HIS84
bTYR257-HIS263

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498
ChainResidueDetails
BASN185
UASN181
ZASN147
ZASN181
eASN147
eASN181
jASN147
jASN181
MLYS146
MTYR171
RTYR7
GASN185
RTHR73
RTYR84
RTHR143
RLYS146
RTYR171
WTYR7
WTHR73
WTYR84
WTHR143
WLYS146
LASN185
WTYR171
bTYR7
bTHR73
bTYR84
bTHR143
bLYS146
bTYR171
gTYR7
gTHR73
gTYR84
QASN185
gTHR143
gLYS146
gTYR171
lTYR7
lTHR73
lTYR84
lTHR143
lLYS146
lTYR171
VASN185
aASN185
fASN185
kASN185
UASN147

site_idSWS_FT_FI2
Number of Residues8
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498
ChainResidueDetails
AASN192
WTYR159
bASP116
bTYR159
gASP116
gTYR159
lASP116
lTYR159
FASN192
KASN192
PASN192
UASN192
ZASN192
eASN192
jASN192
WASP116

site_idSWS_FT_FI3
Number of Residues48
DetailsCARBOHYD: N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:7918443
ChainResidueDetails
DLYS19
ILYS58
ILYS91
ILYS94
NLYS19
NLYS41
NLYS48
NLYS58
NLYS91
NLYS94
SLYS19
DLYS41
SLYS41
SLYS48
SLYS58
SLYS91
SLYS94
XLYS19
XLYS41
XLYS48
XLYS58
XLYS91
DLYS48
XLYS94
cLYS19
cLYS41
cLYS48
cLYS58
cLYS91
cLYS94
hLYS19
hLYS41
hLYS48
DLYS58
hLYS58
hLYS91
hLYS94
mLYS19
mLYS41
mLYS48
mLYS58
mLYS91
mLYS94
DLYS91
DLYS94
ILYS19
ILYS41
ILYS48

site_idSWS_FT_FI4
Number of Residues8
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218
ChainResidueDetails
CASN86
HASN86
MASN86
RASN86
WASN86
bASN86
gASN86
lASN86

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PDB entries from 2025-06-11

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