8RRH

The human prohibitin complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0001649	biological_process	osteoblast differentiation
A	0001850	molecular_function	complement component C3a binding
A	0001851	molecular_function	complement component C3b binding
A	0002639	biological_process	positive regulation of immunoglobulin production
A	0003714	molecular_function	transcription corepressor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005769	cellular_component	early endosome
A	0005886	cellular_component	plasma membrane
A	0006355	biological_process	regulation of DNA-templated transcription
A	0007005	biological_process	mitochondrion organization
A	0007165	biological_process	signal transduction
A	0008285	biological_process	negative regulation of cell population proliferation
A	0009986	cellular_component	cell surface
A	0010628	biological_process	positive regulation of gene expression
A	0010944	biological_process	negative regulation of transcription by competitive promoter binding
A	0016020	cellular_component	membrane
A	0019899	molecular_function	enzyme binding
A	0030308	biological_process	negative regulation of cell growth
A	0031871	molecular_function	proteinase activated receptor binding
A	0032740	biological_process	positive regulation of interleukin-17 production
A	0035632	cellular_component	mitochondrial prohibitin complex
A	0039529	biological_process	RIG-I signaling pathway
A	0040029	biological_process	epigenetic regulation of gene expression
A	0042113	biological_process	B cell activation
A	0042177	biological_process	negative regulation of protein catabolic process
A	0042826	molecular_function	histone deacetylase binding
A	0042981	biological_process	regulation of apoptotic process
A	0043525	biological_process	positive regulation of neuron apoptotic process
A	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
A	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0045917	biological_process	positive regulation of complement activation
A	0046718	biological_process	symbiont entry into host cell
A	0046982	molecular_function	protein heterodimerization activity
A	0048661	biological_process	positive regulation of smooth muscle cell proliferation
A	0050821	biological_process	protein stabilization
A	0050847	biological_process	progesterone receptor signaling pathway
A	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A	0060766	biological_process	negative regulation of androgen receptor signaling pathway
A	0070062	cellular_component	extracellular exosome
A	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
A	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
A	0071354	biological_process	cellular response to interleukin-6
A	0071897	biological_process	DNA biosynthetic process
A	0072538	biological_process	T-helper 17 type immune response
A	0140374	biological_process	antiviral innate immune response
A	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
A	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
B	0000423	biological_process	mitophagy
B	0002639	biological_process	positive regulation of immunoglobulin production
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005741	cellular_component	mitochondrial outer membrane
B	0005743	cellular_component	mitochondrial inner membrane
B	0005886	cellular_component	plasma membrane
B	0006351	biological_process	DNA-templated transcription
B	0006357	biological_process	regulation of transcription by RNA polymerase II
B	0006606	biological_process	protein import into nucleus
B	0007005	biological_process	mitochondrion organization
B	0007062	biological_process	sister chromatid cohesion
B	0009986	cellular_component	cell surface
B	0016020	cellular_component	membrane
B	0016363	cellular_component	nuclear matrix
B	0016477	biological_process	cell migration
B	0030331	molecular_function	nuclear estrogen receptor binding
B	0030449	biological_process	regulation of complement activation
B	0032991	cellular_component	protein-containing complex
B	0033218	molecular_function	amide binding
B	0035632	cellular_component	mitochondrial prohibitin complex
B	0039529	biological_process	RIG-I signaling pathway
B	0042113	biological_process	B cell activation
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0043066	biological_process	negative regulation of apoptotic process
B	0043410	biological_process	positive regulation of MAPK cascade
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0046625	molecular_function	sphingolipid binding
B	0046982	molecular_function	protein heterodimerization activity
B	0050821	biological_process	protein stabilization
B	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
B	0071944	cellular_component	cell periphery
B	0098800	cellular_component	inner mitochondrial membrane protein complex
B	0140374	biological_process	antiviral innate immune response
B	1900208	biological_process	regulation of cardiolipin metabolic process
B	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
C	0000122	biological_process	negative regulation of transcription by RNA polymerase II
C	0001649	biological_process	osteoblast differentiation
C	0001850	molecular_function	complement component C3a binding
C	0001851	molecular_function	complement component C3b binding
C	0002639	biological_process	positive regulation of immunoglobulin production
C	0003714	molecular_function	transcription corepressor activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005769	cellular_component	early endosome
C	0005886	cellular_component	plasma membrane
C	0006355	biological_process	regulation of DNA-templated transcription
C	0007005	biological_process	mitochondrion organization
C	0007165	biological_process	signal transduction
C	0008285	biological_process	negative regulation of cell population proliferation
C	0009986	cellular_component	cell surface
C	0010628	biological_process	positive regulation of gene expression
C	0010944	biological_process	negative regulation of transcription by competitive promoter binding
C	0016020	cellular_component	membrane
C	0019899	molecular_function	enzyme binding
C	0030308	biological_process	negative regulation of cell growth
C	0031871	molecular_function	proteinase activated receptor binding
C	0032740	biological_process	positive regulation of interleukin-17 production
C	0035632	cellular_component	mitochondrial prohibitin complex
C	0039529	biological_process	RIG-I signaling pathway
C	0040029	biological_process	epigenetic regulation of gene expression
C	0042113	biological_process	B cell activation
C	0042177	biological_process	negative regulation of protein catabolic process
C	0042826	molecular_function	histone deacetylase binding
C	0042981	biological_process	regulation of apoptotic process
C	0043525	biological_process	positive regulation of neuron apoptotic process
C	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
C	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0045917	biological_process	positive regulation of complement activation
C	0046718	biological_process	symbiont entry into host cell
C	0046982	molecular_function	protein heterodimerization activity
C	0048661	biological_process	positive regulation of smooth muscle cell proliferation
C	0050821	biological_process	protein stabilization
C	0050847	biological_process	progesterone receptor signaling pathway
C	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
C	0060766	biological_process	negative regulation of androgen receptor signaling pathway
C	0070062	cellular_component	extracellular exosome
C	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
C	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
C	0071354	biological_process	cellular response to interleukin-6
C	0071897	biological_process	DNA biosynthetic process
C	0072538	biological_process	T-helper 17 type immune response
C	0140374	biological_process	antiviral innate immune response
C	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
C	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
D	0000423	biological_process	mitophagy
D	0002639	biological_process	positive regulation of immunoglobulin production
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005741	cellular_component	mitochondrial outer membrane
D	0005743	cellular_component	mitochondrial inner membrane
D	0005886	cellular_component	plasma membrane
D	0006351	biological_process	DNA-templated transcription
D	0006357	biological_process	regulation of transcription by RNA polymerase II
D	0006606	biological_process	protein import into nucleus
D	0007005	biological_process	mitochondrion organization
D	0007062	biological_process	sister chromatid cohesion
D	0009986	cellular_component	cell surface
D	0016020	cellular_component	membrane
D	0016363	cellular_component	nuclear matrix
D	0016477	biological_process	cell migration
D	0030331	molecular_function	nuclear estrogen receptor binding
D	0030449	biological_process	regulation of complement activation
D	0032991	cellular_component	protein-containing complex
D	0033218	molecular_function	amide binding
D	0035632	cellular_component	mitochondrial prohibitin complex
D	0039529	biological_process	RIG-I signaling pathway
D	0042113	biological_process	B cell activation
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0043066	biological_process	negative regulation of apoptotic process
D	0043410	biological_process	positive regulation of MAPK cascade
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0046625	molecular_function	sphingolipid binding
D	0046982	molecular_function	protein heterodimerization activity
D	0050821	biological_process	protein stabilization
D	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
D	0071944	cellular_component	cell periphery
D	0098800	cellular_component	inner mitochondrial membrane protein complex
D	0140374	biological_process	antiviral innate immune response
D	1900208	biological_process	regulation of cardiolipin metabolic process
D	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
E	0000122	biological_process	negative regulation of transcription by RNA polymerase II
E	0001649	biological_process	osteoblast differentiation
E	0001850	molecular_function	complement component C3a binding
E	0001851	molecular_function	complement component C3b binding
E	0002639	biological_process	positive regulation of immunoglobulin production
E	0003714	molecular_function	transcription corepressor activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0005769	cellular_component	early endosome
E	0005886	cellular_component	plasma membrane
E	0006355	biological_process	regulation of DNA-templated transcription
E	0007005	biological_process	mitochondrion organization
E	0007165	biological_process	signal transduction
E	0008285	biological_process	negative regulation of cell population proliferation
E	0009986	cellular_component	cell surface
E	0010628	biological_process	positive regulation of gene expression
E	0010944	biological_process	negative regulation of transcription by competitive promoter binding
E	0016020	cellular_component	membrane
E	0019899	molecular_function	enzyme binding
E	0030308	biological_process	negative regulation of cell growth
E	0031871	molecular_function	proteinase activated receptor binding
E	0032740	biological_process	positive regulation of interleukin-17 production
E	0035632	cellular_component	mitochondrial prohibitin complex
E	0039529	biological_process	RIG-I signaling pathway
E	0040029	biological_process	epigenetic regulation of gene expression
E	0042113	biological_process	B cell activation
E	0042177	biological_process	negative regulation of protein catabolic process
E	0042826	molecular_function	histone deacetylase binding
E	0042981	biological_process	regulation of apoptotic process
E	0043525	biological_process	positive regulation of neuron apoptotic process
E	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
E	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
E	0045892	biological_process	negative regulation of DNA-templated transcription
E	0045893	biological_process	positive regulation of DNA-templated transcription
E	0045917	biological_process	positive regulation of complement activation
E	0046718	biological_process	symbiont entry into host cell
E	0046982	molecular_function	protein heterodimerization activity
E	0048661	biological_process	positive regulation of smooth muscle cell proliferation
E	0050821	biological_process	protein stabilization
E	0050847	biological_process	progesterone receptor signaling pathway
E	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
E	0060766	biological_process	negative regulation of androgen receptor signaling pathway
E	0070062	cellular_component	extracellular exosome
E	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
E	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
E	0071354	biological_process	cellular response to interleukin-6
E	0071897	biological_process	DNA biosynthetic process
E	0072538	biological_process	T-helper 17 type immune response
E	0140374	biological_process	antiviral innate immune response
E	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
E	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
F	0000423	biological_process	mitophagy
F	0002639	biological_process	positive regulation of immunoglobulin production
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005741	cellular_component	mitochondrial outer membrane
F	0005743	cellular_component	mitochondrial inner membrane
F	0005886	cellular_component	plasma membrane
F	0006351	biological_process	DNA-templated transcription
F	0006357	biological_process	regulation of transcription by RNA polymerase II
F	0006606	biological_process	protein import into nucleus
F	0007005	biological_process	mitochondrion organization
F	0007062	biological_process	sister chromatid cohesion
F	0009986	cellular_component	cell surface
F	0016020	cellular_component	membrane
F	0016363	cellular_component	nuclear matrix
F	0016477	biological_process	cell migration
F	0030331	molecular_function	nuclear estrogen receptor binding
F	0030449	biological_process	regulation of complement activation
F	0032991	cellular_component	protein-containing complex
F	0033218	molecular_function	amide binding
F	0035632	cellular_component	mitochondrial prohibitin complex
F	0039529	biological_process	RIG-I signaling pathway
F	0042113	biological_process	B cell activation
F	0042802	molecular_function	identical protein binding
F	0042803	molecular_function	protein homodimerization activity
F	0043066	biological_process	negative regulation of apoptotic process
F	0043410	biological_process	positive regulation of MAPK cascade
F	0045892	biological_process	negative regulation of DNA-templated transcription
F	0046625	molecular_function	sphingolipid binding
F	0046982	molecular_function	protein heterodimerization activity
F	0050821	biological_process	protein stabilization
F	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
F	0071944	cellular_component	cell periphery
F	0098800	cellular_component	inner mitochondrial membrane protein complex
F	0140374	biological_process	antiviral innate immune response
F	1900208	biological_process	regulation of cardiolipin metabolic process
F	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
G	0000122	biological_process	negative regulation of transcription by RNA polymerase II
G	0001649	biological_process	osteoblast differentiation
G	0001850	molecular_function	complement component C3a binding
G	0001851	molecular_function	complement component C3b binding
G	0002639	biological_process	positive regulation of immunoglobulin production
G	0003714	molecular_function	transcription corepressor activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0005769	cellular_component	early endosome
G	0005886	cellular_component	plasma membrane
G	0006355	biological_process	regulation of DNA-templated transcription
G	0007005	biological_process	mitochondrion organization
G	0007165	biological_process	signal transduction
G	0008285	biological_process	negative regulation of cell population proliferation
G	0009986	cellular_component	cell surface
G	0010628	biological_process	positive regulation of gene expression
G	0010944	biological_process	negative regulation of transcription by competitive promoter binding
G	0016020	cellular_component	membrane
G	0019899	molecular_function	enzyme binding
G	0030308	biological_process	negative regulation of cell growth
G	0031871	molecular_function	proteinase activated receptor binding
G	0032740	biological_process	positive regulation of interleukin-17 production
G	0035632	cellular_component	mitochondrial prohibitin complex
G	0039529	biological_process	RIG-I signaling pathway
G	0040029	biological_process	epigenetic regulation of gene expression
G	0042113	biological_process	B cell activation
G	0042177	biological_process	negative regulation of protein catabolic process
G	0042826	molecular_function	histone deacetylase binding
G	0042981	biological_process	regulation of apoptotic process
G	0043525	biological_process	positive regulation of neuron apoptotic process
G	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
G	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
G	0045892	biological_process	negative regulation of DNA-templated transcription
G	0045893	biological_process	positive regulation of DNA-templated transcription
G	0045917	biological_process	positive regulation of complement activation
G	0046718	biological_process	symbiont entry into host cell
G	0046982	molecular_function	protein heterodimerization activity
G	0048661	biological_process	positive regulation of smooth muscle cell proliferation
G	0050821	biological_process	protein stabilization
G	0050847	biological_process	progesterone receptor signaling pathway
G	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
G	0060766	biological_process	negative regulation of androgen receptor signaling pathway
G	0070062	cellular_component	extracellular exosome
G	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
G	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
G	0071354	biological_process	cellular response to interleukin-6
G	0071897	biological_process	DNA biosynthetic process
G	0072538	biological_process	T-helper 17 type immune response
G	0140374	biological_process	antiviral innate immune response
G	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
G	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
H	0000423	biological_process	mitophagy
H	0002639	biological_process	positive regulation of immunoglobulin production
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005741	cellular_component	mitochondrial outer membrane
H	0005743	cellular_component	mitochondrial inner membrane
H	0005886	cellular_component	plasma membrane
H	0006351	biological_process	DNA-templated transcription
H	0006357	biological_process	regulation of transcription by RNA polymerase II
H	0006606	biological_process	protein import into nucleus
H	0007005	biological_process	mitochondrion organization
H	0007062	biological_process	sister chromatid cohesion
H	0009986	cellular_component	cell surface
H	0016020	cellular_component	membrane
H	0016363	cellular_component	nuclear matrix
H	0016477	biological_process	cell migration
H	0030331	molecular_function	nuclear estrogen receptor binding
H	0030449	biological_process	regulation of complement activation
H	0032991	cellular_component	protein-containing complex
H	0033218	molecular_function	amide binding
H	0035632	cellular_component	mitochondrial prohibitin complex
H	0039529	biological_process	RIG-I signaling pathway
H	0042113	biological_process	B cell activation
H	0042802	molecular_function	identical protein binding
H	0042803	molecular_function	protein homodimerization activity
H	0043066	biological_process	negative regulation of apoptotic process
H	0043410	biological_process	positive regulation of MAPK cascade
H	0045892	biological_process	negative regulation of DNA-templated transcription
H	0046625	molecular_function	sphingolipid binding
H	0046982	molecular_function	protein heterodimerization activity
H	0050821	biological_process	protein stabilization
H	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
H	0071944	cellular_component	cell periphery
H	0098800	cellular_component	inner mitochondrial membrane protein complex
H	0140374	biological_process	antiviral innate immune response
H	1900208	biological_process	regulation of cardiolipin metabolic process
H	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
I	0000122	biological_process	negative regulation of transcription by RNA polymerase II
I	0001649	biological_process	osteoblast differentiation
I	0001850	molecular_function	complement component C3a binding
I	0001851	molecular_function	complement component C3b binding
I	0002639	biological_process	positive regulation of immunoglobulin production
I	0003714	molecular_function	transcription corepressor activity
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0005769	cellular_component	early endosome
I	0005886	cellular_component	plasma membrane
I	0006355	biological_process	regulation of DNA-templated transcription
I	0007005	biological_process	mitochondrion organization
I	0007165	biological_process	signal transduction
I	0008285	biological_process	negative regulation of cell population proliferation
I	0009986	cellular_component	cell surface
I	0010628	biological_process	positive regulation of gene expression
I	0010944	biological_process	negative regulation of transcription by competitive promoter binding
I	0016020	cellular_component	membrane
I	0019899	molecular_function	enzyme binding
I	0030308	biological_process	negative regulation of cell growth
I	0031871	molecular_function	proteinase activated receptor binding
I	0032740	biological_process	positive regulation of interleukin-17 production
I	0035632	cellular_component	mitochondrial prohibitin complex
I	0039529	biological_process	RIG-I signaling pathway
I	0040029	biological_process	epigenetic regulation of gene expression
I	0042113	biological_process	B cell activation
I	0042177	biological_process	negative regulation of protein catabolic process
I	0042826	molecular_function	histone deacetylase binding
I	0042981	biological_process	regulation of apoptotic process
I	0043525	biological_process	positive regulation of neuron apoptotic process
I	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
I	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
I	0045892	biological_process	negative regulation of DNA-templated transcription
I	0045893	biological_process	positive regulation of DNA-templated transcription
I	0045917	biological_process	positive regulation of complement activation
I	0046718	biological_process	symbiont entry into host cell
I	0046982	molecular_function	protein heterodimerization activity
I	0048661	biological_process	positive regulation of smooth muscle cell proliferation
I	0050821	biological_process	protein stabilization
I	0050847	biological_process	progesterone receptor signaling pathway
I	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
I	0060766	biological_process	negative regulation of androgen receptor signaling pathway
I	0070062	cellular_component	extracellular exosome
I	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
I	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
I	0071354	biological_process	cellular response to interleukin-6
I	0071897	biological_process	DNA biosynthetic process
I	0072538	biological_process	T-helper 17 type immune response
I	0140374	biological_process	antiviral innate immune response
I	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
I	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
J	0000423	biological_process	mitophagy
J	0002639	biological_process	positive regulation of immunoglobulin production
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005741	cellular_component	mitochondrial outer membrane
J	0005743	cellular_component	mitochondrial inner membrane
J	0005886	cellular_component	plasma membrane
J	0006351	biological_process	DNA-templated transcription
J	0006357	biological_process	regulation of transcription by RNA polymerase II
J	0006606	biological_process	protein import into nucleus
J	0007005	biological_process	mitochondrion organization
J	0007062	biological_process	sister chromatid cohesion
J	0009986	cellular_component	cell surface
J	0016020	cellular_component	membrane
J	0016363	cellular_component	nuclear matrix
J	0016477	biological_process	cell migration
J	0030331	molecular_function	nuclear estrogen receptor binding
J	0030449	biological_process	regulation of complement activation
J	0032991	cellular_component	protein-containing complex
J	0033218	molecular_function	amide binding
J	0035632	cellular_component	mitochondrial prohibitin complex
J	0039529	biological_process	RIG-I signaling pathway
J	0042113	biological_process	B cell activation
J	0042802	molecular_function	identical protein binding
J	0042803	molecular_function	protein homodimerization activity
J	0043066	biological_process	negative regulation of apoptotic process
J	0043410	biological_process	positive regulation of MAPK cascade
J	0045892	biological_process	negative regulation of DNA-templated transcription
J	0046625	molecular_function	sphingolipid binding
J	0046982	molecular_function	protein heterodimerization activity
J	0050821	biological_process	protein stabilization
J	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
J	0071944	cellular_component	cell periphery
J	0098800	cellular_component	inner mitochondrial membrane protein complex
J	0140374	biological_process	antiviral innate immune response
J	1900208	biological_process	regulation of cardiolipin metabolic process
J	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
K	0000122	biological_process	negative regulation of transcription by RNA polymerase II
K	0001649	biological_process	osteoblast differentiation
K	0001850	molecular_function	complement component C3a binding
K	0001851	molecular_function	complement component C3b binding
K	0002639	biological_process	positive regulation of immunoglobulin production
K	0003714	molecular_function	transcription corepressor activity
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0005769	cellular_component	early endosome
K	0005886	cellular_component	plasma membrane
K	0006355	biological_process	regulation of DNA-templated transcription
K	0007005	biological_process	mitochondrion organization
K	0007165	biological_process	signal transduction
K	0008285	biological_process	negative regulation of cell population proliferation
K	0009986	cellular_component	cell surface
K	0010628	biological_process	positive regulation of gene expression
K	0010944	biological_process	negative regulation of transcription by competitive promoter binding
K	0016020	cellular_component	membrane
K	0019899	molecular_function	enzyme binding
K	0030308	biological_process	negative regulation of cell growth
K	0031871	molecular_function	proteinase activated receptor binding
K	0032740	biological_process	positive regulation of interleukin-17 production
K	0035632	cellular_component	mitochondrial prohibitin complex
K	0039529	biological_process	RIG-I signaling pathway
K	0040029	biological_process	epigenetic regulation of gene expression
K	0042113	biological_process	B cell activation
K	0042177	biological_process	negative regulation of protein catabolic process
K	0042826	molecular_function	histone deacetylase binding
K	0042981	biological_process	regulation of apoptotic process
K	0043525	biological_process	positive regulation of neuron apoptotic process
K	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
K	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
K	0045892	biological_process	negative regulation of DNA-templated transcription
K	0045893	biological_process	positive regulation of DNA-templated transcription
K	0045917	biological_process	positive regulation of complement activation
K	0046718	biological_process	symbiont entry into host cell
K	0046982	molecular_function	protein heterodimerization activity
K	0048661	biological_process	positive regulation of smooth muscle cell proliferation
K	0050821	biological_process	protein stabilization
K	0050847	biological_process	progesterone receptor signaling pathway
K	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
K	0060766	biological_process	negative regulation of androgen receptor signaling pathway
K	0070062	cellular_component	extracellular exosome
K	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
K	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
K	0071354	biological_process	cellular response to interleukin-6
K	0071897	biological_process	DNA biosynthetic process
K	0072538	biological_process	T-helper 17 type immune response
K	0140374	biological_process	antiviral innate immune response
K	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
K	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	204
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	12
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P67778","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P67778","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	270
Details	Region: {"description":"Necessary for transcriptional repression","evidences":[{"source":"PubMed","id":"10359819","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	15
Details	Region: {"description":"LC3-interaction region","evidences":[{"source":"PubMed","id":"28017329","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	240
Details	Coiled coil: {"evidences":[{"source":"PubMed","id":"28017329","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6IQE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	5
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAR-2009","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Lilla S.","Zebisch A.","Kolch W."]}},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	5
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	20
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"O35129","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	5
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	5
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---