8RHN

Structure of the 55LCC ATPase complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005730	cellular_component	nucleolus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0042254	biological_process	ribosome biogenesis
A	0042273	biological_process	ribosomal large subunit biogenesis
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005730	cellular_component	nucleolus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0042254	biological_process	ribosome biogenesis
B	0042273	biological_process	ribosomal large subunit biogenesis
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0006260	biological_process	DNA replication
C	0006281	biological_process	DNA repair
C	0042254	biological_process	ribosome biogenesis
C	0042273	biological_process	ribosomal large subunit biogenesis
C	0051301	biological_process	cell division
C	1990275	molecular_function	preribosome binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0006260	biological_process	DNA replication
D	0006281	biological_process	DNA repair
D	0042254	biological_process	ribosome biogenesis
D	0042273	biological_process	ribosomal large subunit biogenesis
D	0051301	biological_process	cell division
D	1990275	molecular_function	preribosome binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005819	cellular_component	spindle
E	0005856	cellular_component	cytoskeleton
E	0007283	biological_process	spermatogenesis
E	0007420	biological_process	brain development
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0030154	biological_process	cell differentiation
E	0042254	biological_process	ribosome biogenesis
E	0042273	biological_process	ribosomal large subunit biogenesis
E	0044877	molecular_function	protein-containing complex binding
E	1990275	molecular_function	preribosome binding
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005819	cellular_component	spindle
F	0005856	cellular_component	cytoskeleton
F	0007283	biological_process	spermatogenesis
F	0007420	biological_process	brain development
F	0016787	molecular_function	hydrolase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0030154	biological_process	cell differentiation
F	0042254	biological_process	ribosome biogenesis
F	0042273	biological_process	ribosomal large subunit biogenesis
F	0044877	molecular_function	protein-containing complex binding
F	1990275	molecular_function	preribosome binding
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005819	cellular_component	spindle
G	0005856	cellular_component	cytoskeleton
G	0007283	biological_process	spermatogenesis
G	0007420	biological_process	brain development
G	0016787	molecular_function	hydrolase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0030154	biological_process	cell differentiation
G	0042254	biological_process	ribosome biogenesis
G	0042273	biological_process	ribosomal large subunit biogenesis
G	0044877	molecular_function	protein-containing complex binding
G	1990275	molecular_function	preribosome binding
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005819	cellular_component	spindle
H	0005856	cellular_component	cytoskeleton
H	0007283	biological_process	spermatogenesis
H	0007420	biological_process	brain development
H	0016787	molecular_function	hydrolase activity
H	0016887	molecular_function	ATP hydrolysis activity
H	0030154	biological_process	cell differentiation
H	0042254	biological_process	ribosome biogenesis
H	0042273	biological_process	ribosomal large subunit biogenesis
H	0044877	molecular_function	protein-containing complex binding
H	1990275	molecular_function	preribosome binding
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005634	cellular_component	nucleus
I	0005737	cellular_component	cytoplasm
I	0005819	cellular_component	spindle
I	0005856	cellular_component	cytoskeleton
I	0016787	molecular_function	hydrolase activity
I	0016887	molecular_function	ATP hydrolysis activity
I	0042254	biological_process	ribosome biogenesis
I	0042273	biological_process	ribosomal large subunit biogenesis
I	0044877	molecular_function	protein-containing complex binding
I	1990275	molecular_function	preribosome binding
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0005819	cellular_component	spindle
J	0005856	cellular_component	cytoskeleton
J	0016787	molecular_function	hydrolase activity
J	0016887	molecular_function	ATP hydrolysis activity
J	0042254	biological_process	ribosome biogenesis
J	0042273	biological_process	ribosomal large subunit biogenesis
J	0044877	molecular_function	protein-containing complex binding
J	1990275	molecular_function	preribosome binding
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005819	cellular_component	spindle
K	0005856	cellular_component	cytoskeleton
K	0007283	biological_process	spermatogenesis
K	0007420	biological_process	brain development
K	0016787	molecular_function	hydrolase activity
K	0016887	molecular_function	ATP hydrolysis activity
K	0030154	biological_process	cell differentiation
K	0042254	biological_process	ribosome biogenesis
K	0042273	biological_process	ribosomal large subunit biogenesis
K	0044877	molecular_function	protein-containing complex binding
K	1990275	molecular_function	preribosome binding
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005819	cellular_component	spindle
L	0005856	cellular_component	cytoskeleton
L	0007283	biological_process	spermatogenesis
L	0007420	biological_process	brain development
L	0016787	molecular_function	hydrolase activity
L	0016887	molecular_function	ATP hydrolysis activity
L	0030154	biological_process	cell differentiation
L	0042254	biological_process	ribosome biogenesis
L	0042273	biological_process	ribosomal large subunit biogenesis
L	0044877	molecular_function	protein-containing complex binding
L	1990275	molecular_function	preribosome binding
M	0005515	molecular_function	protein binding
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0005739	cellular_component	mitochondrion
M	0005819	cellular_component	spindle
M	0005856	cellular_component	cytoskeleton
M	0007283	biological_process	spermatogenesis
M	0007420	biological_process	brain development
M	0016787	molecular_function	hydrolase activity
M	0016887	molecular_function	ATP hydrolysis activity
M	0030154	biological_process	cell differentiation
M	0042254	biological_process	ribosome biogenesis
M	0042273	biological_process	ribosomal large subunit biogenesis
M	0044877	molecular_function	protein-containing complex binding
M	1990275	molecular_function	preribosome binding
N	0005515	molecular_function	protein binding
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0005739	cellular_component	mitochondrion
N	0005819	cellular_component	spindle
N	0005856	cellular_component	cytoskeleton
N	0007283	biological_process	spermatogenesis
N	0007420	biological_process	brain development
N	0016787	molecular_function	hydrolase activity
N	0016887	molecular_function	ATP hydrolysis activity
N	0030154	biological_process	cell differentiation
N	0042254	biological_process	ribosome biogenesis
N	0042273	biological_process	ribosomal large subunit biogenesis
N	0044877	molecular_function	protein-containing complex binding
N	1990275	molecular_function	preribosome binding
O	0005515	molecular_function	protein binding
O	0005524	molecular_function	ATP binding
O	0005634	cellular_component	nucleus
O	0005737	cellular_component	cytoplasm
O	0005819	cellular_component	spindle
O	0005856	cellular_component	cytoskeleton
O	0016787	molecular_function	hydrolase activity
O	0016887	molecular_function	ATP hydrolysis activity
O	0042254	biological_process	ribosome biogenesis
O	0042273	biological_process	ribosomal large subunit biogenesis
O	0044877	molecular_function	protein-containing complex binding
O	1990275	molecular_function	preribosome binding
P	0005515	molecular_function	protein binding
P	0005524	molecular_function	ATP binding
P	0005634	cellular_component	nucleus
P	0005737	cellular_component	cytoplasm
P	0005819	cellular_component	spindle
P	0005856	cellular_component	cytoskeleton
P	0016787	molecular_function	hydrolase activity
P	0016887	molecular_function	ATP hydrolysis activity
P	0042254	biological_process	ribosome biogenesis
P	0042273	biological_process	ribosomal large subunit biogenesis
P	0044877	molecular_function	protein-containing complex binding
P	1990275	molecular_function	preribosome binding

Functional Information from PROSITE/UniProt

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. VvVVgATNrpdaLDpALr.R

Chain	Residue	Details
O	VAL338-ARG356
O	VAL622-ARG640
K	VAL493-ARG511
K	VAL766-ARG784

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:38554706, ECO:0007744|PDB:8CIH

Chain	Residue	Details
C	SER202
E	GLY668
F	GLY394
F	GLY668
G	GLY394
G	GLY668
H	GLY394
H	GLY668
D	SER202
P	GLY241
P	GLY505
I	GLY241
I	GLY505
J	GLY241
J	GLY505
E	GLY394

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:22814378

Chain	Residue	Details
C	MET1
D	MET1
I	MET1
J	MET1
E	THR272
F	THR272
G	THR272
H	THR272

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
C	SER69
E	SER279
F	SER274
F	SER279
G	SER274
G	SER279
H	SER274
H	SER279
C	SER73
D	SER69
D	SER73
M	SER274
M	SER279
N	SER274
N	SER279
E	SER274

---

site_id	SWS_FT_FI4
Number of Residues	16
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
K	LYS859
F	LYS859
G	LYS859
H	LYS859
L	LYS859
M	LYS859
N	LYS859
E	LYS859

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