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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8RDX

PGGtase I in complex with probe BAY-6092

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0008318molecular_functionprotein prenyltransferase activity
A0018342biological_processprotein prenylation
B0003824molecular_functioncatalytic activity
B0004659molecular_functionprenyltransferase activity
B0004661molecular_functionprotein geranylgeranyltransferase activity
B0004662molecular_functionCAAX-protein geranylgeranyltransferase activity
B0005515molecular_functionprotein binding
B0005953cellular_componentCAAX-protein geranylgeranyltransferase complex
B0008270molecular_functionzinc ion binding
B0008284biological_processpositive regulation of cell population proliferation
B0008318molecular_functionprotein prenyltransferase activity
B0016740molecular_functiontransferase activity
B0018344biological_processprotein geranylgeranylation
B0036094molecular_functionsmall molecule binding
B0042277molecular_functionpeptide binding
B0045787biological_processpositive regulation of cell cycle
B0046872molecular_functionmetal ion binding
B1901363molecular_functionheterocyclic compound binding
C0008318molecular_functionprotein prenyltransferase activity
C0018342biological_processprotein prenylation
D0003824molecular_functioncatalytic activity
D0004659molecular_functionprenyltransferase activity
D0004661molecular_functionprotein geranylgeranyltransferase activity
D0004662molecular_functionCAAX-protein geranylgeranyltransferase activity
D0005515molecular_functionprotein binding
D0005953cellular_componentCAAX-protein geranylgeranyltransferase complex
D0008270molecular_functionzinc ion binding
D0008284biological_processpositive regulation of cell population proliferation
D0008318molecular_functionprotein prenyltransferase activity
D0016740molecular_functiontransferase activity
D0018344biological_processprotein geranylgeranylation
D0036094molecular_functionsmall molecule binding
D0042277molecular_functionpeptide binding
D0045787biological_processpositive regulation of cell cycle
D0046872molecular_functionmetal ion binding
D1901363molecular_functionheterocyclic compound binding
E0008318molecular_functionprotein prenyltransferase activity
E0018342biological_processprotein prenylation
F0003824molecular_functioncatalytic activity
F0004659molecular_functionprenyltransferase activity
F0004661molecular_functionprotein geranylgeranyltransferase activity
F0004662molecular_functionCAAX-protein geranylgeranyltransferase activity
F0005515molecular_functionprotein binding
F0005953cellular_componentCAAX-protein geranylgeranyltransferase complex
F0008270molecular_functionzinc ion binding
F0008284biological_processpositive regulation of cell population proliferation
F0008318molecular_functionprotein prenyltransferase activity
F0016740molecular_functiontransferase activity
F0018344biological_processprotein geranylgeranylation
F0036094molecular_functionsmall molecule binding
F0042277molecular_functionpeptide binding
F0045787biological_processpositive regulation of cell cycle
F0046872molecular_functionmetal ion binding
F1901363molecular_functionheterocyclic compound binding
G0008318molecular_functionprotein prenyltransferase activity
G0018342biological_processprotein prenylation
H0003824molecular_functioncatalytic activity
H0004659molecular_functionprenyltransferase activity
H0004661molecular_functionprotein geranylgeranyltransferase activity
H0004662molecular_functionCAAX-protein geranylgeranyltransferase activity
H0005515molecular_functionprotein binding
H0005953cellular_componentCAAX-protein geranylgeranyltransferase complex
H0008270molecular_functionzinc ion binding
H0008284biological_processpositive regulation of cell population proliferation
H0008318molecular_functionprotein prenyltransferase activity
H0016740molecular_functiontransferase activity
H0018344biological_processprotein geranylgeranylation
H0036094molecular_functionsmall molecule binding
H0042277molecular_functionpeptide binding
H0045787biological_processpositive regulation of cell cycle
H0046872molecular_functionmetal ion binding
H1901363molecular_functionheterocyclic compound binding
I0008318molecular_functionprotein prenyltransferase activity
I0018342biological_processprotein prenylation
J0003824molecular_functioncatalytic activity
J0004659molecular_functionprenyltransferase activity
J0004661molecular_functionprotein geranylgeranyltransferase activity
J0004662molecular_functionCAAX-protein geranylgeranyltransferase activity
J0005515molecular_functionprotein binding
J0005953cellular_componentCAAX-protein geranylgeranyltransferase complex
J0008270molecular_functionzinc ion binding
J0008284biological_processpositive regulation of cell population proliferation
J0008318molecular_functionprotein prenyltransferase activity
J0016740molecular_functiontransferase activity
J0018344biological_processprotein geranylgeranylation
J0036094molecular_functionsmall molecule binding
J0042277molecular_functionpeptide binding
J0045787biological_processpositive regulation of cell cycle
J0046872molecular_functionmetal ion binding
J1901363molecular_functionheterocyclic compound binding
K0008318molecular_functionprotein prenyltransferase activity
K0018342biological_processprotein prenylation
L0003824molecular_functioncatalytic activity
L0004659molecular_functionprenyltransferase activity
L0004661molecular_functionprotein geranylgeranyltransferase activity
L0004662molecular_functionCAAX-protein geranylgeranyltransferase activity
L0005515molecular_functionprotein binding
L0005953cellular_componentCAAX-protein geranylgeranyltransferase complex
L0008270molecular_functionzinc ion binding
L0008284biological_processpositive regulation of cell population proliferation
L0008318molecular_functionprotein prenyltransferase activity
L0016740molecular_functiontransferase activity
L0018344biological_processprotein geranylgeranylation
L0036094molecular_functionsmall molecule binding
L0042277molecular_functionpeptide binding
L0045787biological_processpositive regulation of cell cycle
L0046872molecular_functionmetal ion binding
L1901363molecular_functionheterocyclic compound binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues204
DetailsRepeat: {"description":"PFTA 1"}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues204
DetailsRepeat: {"description":"PFTA 2"}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues192
DetailsRepeat: {"description":"PFTA 3"}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues204
DetailsRepeat: {"description":"PFTA 4"}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues204
DetailsRepeat: {"description":"PFTA 5"}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues252
DetailsRepeat: {"description":"PFTB 1","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues246
DetailsRepeat: {"description":"PFTB 2","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues234
DetailsRepeat: {"description":"PFTB 3","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues252
DetailsRepeat: {"description":"PFTB 4","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues66
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"14609943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1N4P","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
Catalytic Information from CSA
site_idMCSA1
Number of Residues1
DetailsM-CSA 484
ChainResidueDetails
ALYS164electrostatic stabiliser
site_idMCSA2
Number of Residues1
DetailsM-CSA 484
ChainResidueDetails
CLYS164electrostatic stabiliser
site_idMCSA3
Number of Residues1
DetailsM-CSA 484
ChainResidueDetails
ELYS164electrostatic stabiliser
site_idMCSA4
Number of Residues1
DetailsM-CSA 484
ChainResidueDetails
GLYS164electrostatic stabiliser
site_idMCSA5
Number of Residues1
DetailsM-CSA 484
ChainResidueDetails
ILYS164electrostatic stabiliser
site_idMCSA6
Number of Residues1
DetailsM-CSA 484
ChainResidueDetails
KLYS164electrostatic stabiliser

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PDB entries from 2025-07-09

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