8QYT

Human Pyridoxine-5'-phosphate oxidase in complex with PLP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004733	molecular_function	pyridoxamine phosphate oxidase activity
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0006725	biological_process	obsolete cellular aromatic compound metabolic process
A	0008615	biological_process	pyridoxine biosynthetic process
A	0010181	molecular_function	FMN binding
A	0016491	molecular_function	oxidoreductase activity
A	0030170	molecular_function	pyridoxal phosphate binding
A	0042803	molecular_function	protein homodimerization activity
A	0042816	biological_process	vitamin B6 metabolic process
A	0042818	biological_process	pyridoxamine metabolic process
A	0042822	biological_process	pyridoxal phosphate metabolic process
A	0042823	biological_process	pyridoxal phosphate biosynthetic process
A	1901615	biological_process	organic hydroxy compound metabolic process

Functional Information from PROSITE/UniProt

site_id	PS01064
Number of Residues	14
Details	PYRIDOX_OXIDASE Pyridoxamine 5'-phosphate oxidase signature. MEFWQgqtnRLHDR

Chain	Residue	Details
A	MET216-ARG229

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P0AFI7

Chain	Residue	Details
A	ARG42
A	GLN139
A	TRP219
A	ARG225
A	ARG229

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site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:12824491

Chain	Residue	Details
A	ARG95
A	LYS100
A	PHE110
A	ARG116
A	TYR157
A	ARG161
A	SER165
A	GLN174

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	THR238

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	SER241

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