8QU1

mt-LSU assembly intermediate in GTPBP8 knock-out cells, state 1

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0003723	molecular_function	RNA binding
0	0003735	molecular_function	structural constituent of ribosome
0	0005515	molecular_function	protein binding
0	0005739	cellular_component	mitochondrion
0	0005743	cellular_component	mitochondrial inner membrane
0	0005759	cellular_component	mitochondrial matrix
0	0005761	cellular_component	mitochondrial ribosome
0	0005762	cellular_component	mitochondrial large ribosomal subunit
0	0005840	cellular_component	ribosome
0	0006412	biological_process	translation
0	0015934	cellular_component	large ribosomal subunit
0	0032543	biological_process	mitochondrial translation
0	1990904	cellular_component	ribonucleoprotein complex
1	0003735	molecular_function	structural constituent of ribosome
1	0005737	cellular_component	cytoplasm
1	0005739	cellular_component	mitochondrion
1	0005743	cellular_component	mitochondrial inner membrane
1	0005762	cellular_component	mitochondrial large ribosomal subunit
1	0005840	cellular_component	ribosome
1	0006412	biological_process	translation
1	0032543	biological_process	mitochondrial translation
1	1990904	cellular_component	ribonucleoprotein complex
2	0003735	molecular_function	structural constituent of ribosome
2	0005739	cellular_component	mitochondrion
2	0005743	cellular_component	mitochondrial inner membrane
2	0005761	cellular_component	mitochondrial ribosome
2	0005762	cellular_component	mitochondrial large ribosomal subunit
2	0005840	cellular_component	ribosome
2	0006412	biological_process	translation
2	0032543	biological_process	mitochondrial translation
2	1990904	cellular_component	ribonucleoprotein complex
3	0003735	molecular_function	structural constituent of ribosome
3	0005739	cellular_component	mitochondrion
3	0005743	cellular_component	mitochondrial inner membrane
3	0005761	cellular_component	mitochondrial ribosome
3	0005762	cellular_component	mitochondrial large ribosomal subunit
3	0005840	cellular_component	ribosome
3	0006412	biological_process	translation
3	0032543	biological_process	mitochondrial translation
3	1990904	cellular_component	ribonucleoprotein complex
5	0003723	molecular_function	RNA binding
5	0003735	molecular_function	structural constituent of ribosome
5	0005739	cellular_component	mitochondrion
5	0005743	cellular_component	mitochondrial inner membrane
5	0005761	cellular_component	mitochondrial ribosome
5	0005762	cellular_component	mitochondrial large ribosomal subunit
5	0005840	cellular_component	ribosome
5	0006412	biological_process	translation
5	0032543	biological_process	mitochondrial translation
5	1990904	cellular_component	ribonucleoprotein complex
6	0005515	molecular_function	protein binding
6	0005739	cellular_component	mitochondrion
6	0005743	cellular_component	mitochondrial inner membrane
6	0005762	cellular_component	mitochondrial large ribosomal subunit
6	0005829	cellular_component	cytosol
6	0005840	cellular_component	ribosome
6	0032543	biological_process	mitochondrial translation
6	1990904	cellular_component	ribonucleoprotein complex
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005654	cellular_component	nucleoplasm
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005762	cellular_component	mitochondrial large ribosomal subunit
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0032543	biological_process	mitochondrial translation
D	1990904	cellular_component	ribonucleoprotein complex
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0005762	cellular_component	mitochondrial large ribosomal subunit
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0032543	biological_process	mitochondrial translation
E	1990904	cellular_component	ribonucleoprotein complex
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005515	molecular_function	protein binding
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005762	cellular_component	mitochondrial large ribosomal subunit
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0032543	biological_process	mitochondrial translation
F	1990904	cellular_component	ribonucleoprotein complex
H	0003723	molecular_function	RNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005515	molecular_function	protein binding
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0005761	cellular_component	mitochondrial ribosome
H	0005762	cellular_component	mitochondrial large ribosomal subunit
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0032543	biological_process	mitochondrial translation
H	1990904	cellular_component	ribonucleoprotein complex
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005515	molecular_function	protein binding
I	0005654	cellular_component	nucleoplasm
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0005762	cellular_component	mitochondrial large ribosomal subunit
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0032543	biological_process	mitochondrial translation
I	1990904	cellular_component	ribonucleoprotein complex
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005515	molecular_function	protein binding
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0005761	cellular_component	mitochondrial ribosome
J	0005762	cellular_component	mitochondrial large ribosomal subunit
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0032543	biological_process	mitochondrial translation
J	0070180	molecular_function	large ribosomal subunit rRNA binding
J	1990904	cellular_component	ribonucleoprotein complex
K	0003723	molecular_function	RNA binding
K	0003729	molecular_function	mRNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005515	molecular_function	protein binding
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0005761	cellular_component	mitochondrial ribosome
K	0005762	cellular_component	mitochondrial large ribosomal subunit
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0017148	biological_process	negative regulation of translation
K	0032543	biological_process	mitochondrial translation
K	1990904	cellular_component	ribonucleoprotein complex
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0005762	cellular_component	mitochondrial large ribosomal subunit
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0032543	biological_process	mitochondrial translation
L	1990904	cellular_component	ribonucleoprotein complex
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005515	molecular_function	protein binding
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0005762	cellular_component	mitochondrial large ribosomal subunit
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0015934	cellular_component	large ribosomal subunit
M	0032543	biological_process	mitochondrial translation
M	1990830	biological_process	cellular response to leukemia inhibitory factor
M	1990904	cellular_component	ribonucleoprotein complex
N	0003735	molecular_function	structural constituent of ribosome
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0005762	cellular_component	mitochondrial large ribosomal subunit
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0015934	cellular_component	large ribosomal subunit
N	0019843	molecular_function	rRNA binding
N	0032543	biological_process	mitochondrial translation
N	1990904	cellular_component	ribonucleoprotein complex
O	0003735	molecular_function	structural constituent of ribosome
O	0005515	molecular_function	protein binding
O	0005739	cellular_component	mitochondrion
O	0005743	cellular_component	mitochondrial inner membrane
O	0005762	cellular_component	mitochondrial large ribosomal subunit
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0019904	molecular_function	protein domain specific binding
O	0032543	biological_process	mitochondrial translation
O	1990904	cellular_component	ribonucleoprotein complex
P	0003723	molecular_function	RNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005515	molecular_function	protein binding
P	0005615	cellular_component	extracellular space
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0005761	cellular_component	mitochondrial ribosome
P	0005762	cellular_component	mitochondrial large ribosomal subunit
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0008097	molecular_function	5S rRNA binding
P	0032543	biological_process	mitochondrial translation
P	0035928	biological_process	rRNA import into mitochondrion
P	1990904	cellular_component	ribonucleoprotein complex
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005739	cellular_component	mitochondrion
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0005762	cellular_component	mitochondrial large ribosomal subunit
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0032543	biological_process	mitochondrial translation
Q	1990904	cellular_component	ribonucleoprotein complex
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005515	molecular_function	protein binding
R	0005739	cellular_component	mitochondrion
R	0005743	cellular_component	mitochondrial inner membrane
R	0005761	cellular_component	mitochondrial ribosome
R	0005762	cellular_component	mitochondrial large ribosomal subunit
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0019843	molecular_function	rRNA binding
R	0032543	biological_process	mitochondrial translation
R	1990904	cellular_component	ribonucleoprotein complex
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005737	cellular_component	cytoplasm
S	0005739	cellular_component	mitochondrion
S	0005743	cellular_component	mitochondrial inner membrane
S	0005762	cellular_component	mitochondrial large ribosomal subunit
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0032543	biological_process	mitochondrial translation
S	1990904	cellular_component	ribonucleoprotein complex
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005739	cellular_component	mitochondrion
T	0005743	cellular_component	mitochondrial inner membrane
T	0005762	cellular_component	mitochondrial large ribosomal subunit
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0015934	cellular_component	large ribosomal subunit
T	0032543	biological_process	mitochondrial translation
T	1990904	cellular_component	ribonucleoprotein complex
U	0001650	cellular_component	fibrillar center
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005515	molecular_function	protein binding
U	0005739	cellular_component	mitochondrion
U	0005743	cellular_component	mitochondrial inner membrane
U	0005762	cellular_component	mitochondrial large ribosomal subunit
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0032543	biological_process	mitochondrial translation
U	0044391	cellular_component	ribosomal subunit
U	1990904	cellular_component	ribonucleoprotein complex
V	0003723	molecular_function	RNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005739	cellular_component	mitochondrion
V	0005743	cellular_component	mitochondrial inner membrane
V	0005762	cellular_component	mitochondrial large ribosomal subunit
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0032543	biological_process	mitochondrial translation
V	1990904	cellular_component	ribonucleoprotein complex
W	0003723	molecular_function	RNA binding
W	0003735	molecular_function	structural constituent of ribosome
W	0005515	molecular_function	protein binding
W	0005739	cellular_component	mitochondrion
W	0005743	cellular_component	mitochondrial inner membrane
W	0005762	cellular_component	mitochondrial large ribosomal subunit
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0032543	biological_process	mitochondrial translation
W	1990904	cellular_component	ribonucleoprotein complex
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005515	molecular_function	protein binding
X	0005739	cellular_component	mitochondrion
X	0005743	cellular_component	mitochondrial inner membrane
X	0005761	cellular_component	mitochondrial ribosome
X	0005762	cellular_component	mitochondrial large ribosomal subunit
X	0005829	cellular_component	cytosol
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0032543	biological_process	mitochondrial translation
X	1990904	cellular_component	ribonucleoprotein complex
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005739	cellular_component	mitochondrion
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0005761	cellular_component	mitochondrial ribosome
Y	0005762	cellular_component	mitochondrial large ribosomal subunit
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0032543	biological_process	mitochondrial translation
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005739	cellular_component	mitochondrion
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0005762	cellular_component	mitochondrial large ribosomal subunit
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
Z	0015934	cellular_component	large ribosomal subunit
Z	0032543	biological_process	mitochondrial translation
Z	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FrpgqyvDvtAkTiGKGfqGvmkR

Chain	Residue	Details
E	PHE198-ARG221

---

site_id	PS00783
Number of Residues	23
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. IYGMLPknlh.RRtmmerLhLFpD

Chain	Residue	Details
K	ILE108-ASP130

---

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. GDtVeILeGkdAGkq.GkV

Chain	Residue	Details
V	GLY59-VAL76

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	25
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	33
Details	Domain: {"description":"KOW"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28892042","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7QH7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28892042","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---