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8PWL

Cryo-EM structure of a full-length HACE1 dimer

Functional Information from GO Data
ChainGOidnamespacecontents
A0000139cellular_componentGolgi membrane
A0000209biological_processprotein polyubiquitination
A0004842molecular_functionubiquitin-protein transferase activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005783cellular_componentendoplasmic reticulum
A0005794cellular_componentGolgi apparatus
A0006511biological_processubiquitin-dependent protein catabolic process
A0007030biological_processGolgi organization
A0016020cellular_componentmembrane
A0016567biological_processprotein ubiquitination
A0016601biological_processRac protein signal transduction
A0016604cellular_componentnuclear body
A0016740molecular_functiontransferase activity
A0030334biological_processregulation of cell migration
A0031267molecular_functionsmall GTPase binding
A0032580cellular_componentGolgi cisterna membrane
A0061025biological_processmembrane fusion
A0061630molecular_functionubiquitin protein ligase activity
A0070936biological_processprotein K48-linked ubiquitination
B0000139cellular_componentGolgi membrane
B0000209biological_processprotein polyubiquitination
B0004842molecular_functionubiquitin-protein transferase activity
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005783cellular_componentendoplasmic reticulum
B0005794cellular_componentGolgi apparatus
B0006511biological_processubiquitin-dependent protein catabolic process
B0007030biological_processGolgi organization
B0016020cellular_componentmembrane
B0016567biological_processprotein ubiquitination
B0016601biological_processRac protein signal transduction
B0016604cellular_componentnuclear body
B0016740molecular_functiontransferase activity
B0030334biological_processregulation of cell migration
B0031267molecular_functionsmall GTPase binding
B0032580cellular_componentGolgi cisterna membrane
B0061025biological_processmembrane fusion
B0061630molecular_functionubiquitin protein ligase activity
B0070936biological_processprotein K48-linked ubiquitination
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Glycyl thioester intermediate
ChainResidueDetails
ACYS876
BCYS876

219869

PDB entries from 2024-05-15

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