8PPL

MERS-CoV Nsp1 bound to the human 43S pre-initiation complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
Aa	0002181	biological_process	cytoplasmic translation
Aa	0003723	molecular_function	RNA binding
Aa	0003729	molecular_function	mRNA binding
Aa	0003735	molecular_function	structural constituent of ribosome
Aa	0005515	molecular_function	protein binding
Aa	0005654	cellular_component	nucleoplasm
Aa	0005730	cellular_component	nucleolus
Aa	0005737	cellular_component	cytoplasm
Aa	0005783	cellular_component	endoplasmic reticulum
Aa	0005791	cellular_component	rough endoplasmic reticulum
Aa	0005829	cellular_component	cytosol
Aa	0005840	cellular_component	ribosome
Aa	0006412	biological_process	translation
Aa	0015935	cellular_component	small ribosomal subunit
Aa	0016020	cellular_component	membrane
Aa	0022626	cellular_component	cytosolic ribosome
Aa	0022627	cellular_component	cytosolic small ribosomal subunit
Aa	0033119	biological_process	negative regulation of RNA splicing
Aa	0045202	cellular_component	synapse
Aa	0045296	molecular_function	cadherin binding
Aa	0070062	cellular_component	extracellular exosome
Aa	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
Aa	1990904	cellular_component	ribonucleoprotein complex
AA	0000028	biological_process	ribosomal small subunit assembly
AA	0001618	molecular_function	virus receptor activity
AA	0002181	biological_process	cytoplasmic translation
AA	0003677	molecular_function	DNA binding
AA	0003723	molecular_function	RNA binding
AA	0003735	molecular_function	structural constituent of ribosome
AA	0005055	molecular_function	laminin receptor activity
AA	0005515	molecular_function	protein binding
AA	0005634	cellular_component	nucleus
AA	0005654	cellular_component	nucleoplasm
AA	0005737	cellular_component	cytoplasm
AA	0005829	cellular_component	cytosol
AA	0005840	cellular_component	ribosome
AA	0005886	cellular_component	plasma membrane
AA	0006412	biological_process	translation
AA	0007155	biological_process	cell adhesion
AA	0015935	cellular_component	small ribosomal subunit
AA	0016020	cellular_component	membrane
AA	0022626	cellular_component	cytosolic ribosome
AA	0022627	cellular_component	cytosolic small ribosomal subunit
AA	0043022	molecular_function	ribosome binding
AA	0043236	molecular_function	laminin binding
AA	0046718	biological_process	symbiont entry into host cell
AA	0070062	cellular_component	extracellular exosome
AA	0140374	biological_process	antiviral innate immune response
AA	1990904	cellular_component	ribonucleoprotein complex
Ab	0000028	biological_process	ribosomal small subunit assembly
Ab	0002181	biological_process	cytoplasmic translation
Ab	0003677	molecular_function	DNA binding
Ab	0003723	molecular_function	RNA binding
Ab	0003735	molecular_function	structural constituent of ribosome
Ab	0005515	molecular_function	protein binding
Ab	0005634	cellular_component	nucleus
Ab	0005654	cellular_component	nucleoplasm
Ab	0005730	cellular_component	nucleolus
Ab	0005737	cellular_component	cytoplasm
Ab	0005829	cellular_component	cytosol
Ab	0005840	cellular_component	ribosome
Ab	0006364	biological_process	rRNA processing
Ab	0006412	biological_process	translation
Ab	0008270	molecular_function	zinc ion binding
Ab	0014069	cellular_component	postsynaptic density
Ab	0022626	cellular_component	cytosolic ribosome
Ab	0022627	cellular_component	cytosolic small ribosomal subunit
Ab	0032040	cellular_component	small-subunit processome
Ab	0042274	biological_process	ribosomal small subunit biogenesis
Ab	0046872	molecular_function	metal ion binding
Ab	0098793	cellular_component	presynapse
Ab	0098978	cellular_component	glutamatergic synapse
Ab	0098982	cellular_component	GABA-ergic synapse
Ab	1990904	cellular_component	ribonucleoprotein complex
AB	0002181	biological_process	cytoplasmic translation
AB	0003723	molecular_function	RNA binding
AB	0003735	molecular_function	structural constituent of ribosome
AB	0005515	molecular_function	protein binding
AB	0005634	cellular_component	nucleus
AB	0005654	cellular_component	nucleoplasm
AB	0005730	cellular_component	nucleolus
AB	0005737	cellular_component	cytoplasm
AB	0005783	cellular_component	endoplasmic reticulum
AB	0005829	cellular_component	cytosol
AB	0005840	cellular_component	ribosome
AB	0005925	cellular_component	focal adhesion
AB	0006412	biological_process	translation
AB	0006413	biological_process	translational initiation
AB	0022626	cellular_component	cytosolic ribosome
AB	0022627	cellular_component	cytosolic small ribosomal subunit
AB	0030154	biological_process	cell differentiation
AB	0032040	cellular_component	small-subunit processome
AB	0042274	biological_process	ribosomal small subunit biogenesis
AB	0043066	biological_process	negative regulation of apoptotic process
AB	0048027	molecular_function	mRNA 5'-UTR binding
AB	0070062	cellular_component	extracellular exosome
AB	1990904	cellular_component	ribonucleoprotein complex
Ac	0000028	biological_process	ribosomal small subunit assembly
Ac	0002181	biological_process	cytoplasmic translation
Ac	0003723	molecular_function	RNA binding
Ac	0003735	molecular_function	structural constituent of ribosome
Ac	0005515	molecular_function	protein binding
Ac	0005654	cellular_component	nucleoplasm
Ac	0005730	cellular_component	nucleolus
Ac	0005737	cellular_component	cytoplasm
Ac	0005791	cellular_component	rough endoplasmic reticulum
Ac	0005829	cellular_component	cytosol
Ac	0005840	cellular_component	ribosome
Ac	0006364	biological_process	rRNA processing
Ac	0006412	biological_process	translation
Ac	0015935	cellular_component	small ribosomal subunit
Ac	0022626	cellular_component	cytosolic ribosome
Ac	0022627	cellular_component	cytosolic small ribosomal subunit
Ac	0030490	biological_process	maturation of SSU-rRNA
Ac	0032040	cellular_component	small-subunit processome
Ac	0042254	biological_process	ribosome biogenesis
Ac	0042274	biological_process	ribosomal small subunit biogenesis
Ac	0045202	cellular_component	synapse
Ac	0070062	cellular_component	extracellular exosome
Ac	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
Ac	1990904	cellular_component	ribonucleoprotein complex
AC	0002181	biological_process	cytoplasmic translation
AC	0003723	molecular_function	RNA binding
AC	0003729	molecular_function	mRNA binding
AC	0003735	molecular_function	structural constituent of ribosome
AC	0005515	molecular_function	protein binding
AC	0005634	cellular_component	nucleus
AC	0005654	cellular_component	nucleoplasm
AC	0005730	cellular_component	nucleolus
AC	0005737	cellular_component	cytoplasm
AC	0005829	cellular_component	cytosol
AC	0005840	cellular_component	ribosome
AC	0005925	cellular_component	focal adhesion
AC	0006412	biological_process	translation
AC	0015935	cellular_component	small ribosomal subunit
AC	0016020	cellular_component	membrane
AC	0017134	molecular_function	fibroblast growth factor binding
AC	0019899	molecular_function	enzyme binding
AC	0022626	cellular_component	cytosolic ribosome
AC	0022627	cellular_component	cytosolic small ribosomal subunit
AC	0045296	molecular_function	cadherin binding
AC	0051443	biological_process	positive regulation of ubiquitin-protein transferase activity
AC	0070062	cellular_component	extracellular exosome
AC	1990904	cellular_component	ribonucleoprotein complex
Ad	0002181	biological_process	cytoplasmic translation
Ad	0003735	molecular_function	structural constituent of ribosome
Ad	0005654	cellular_component	nucleoplasm
Ad	0005737	cellular_component	cytoplasm
Ad	0005783	cellular_component	endoplasmic reticulum
Ad	0005791	cellular_component	rough endoplasmic reticulum
Ad	0005829	cellular_component	cytosol
Ad	0005840	cellular_component	ribosome
Ad	0005925	cellular_component	focal adhesion
Ad	0006412	biological_process	translation
Ad	0008270	molecular_function	zinc ion binding
Ad	0015935	cellular_component	small ribosomal subunit
Ad	0022626	cellular_component	cytosolic ribosome
Ad	0022627	cellular_component	cytosolic small ribosomal subunit
Ad	0046872	molecular_function	metal ion binding
Ad	0070062	cellular_component	extracellular exosome
Ad	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
Ad	1990904	cellular_component	ribonucleoprotein complex
AD	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
AD	0002181	biological_process	cytoplasmic translation
AD	0002183	biological_process	cytoplasmic translational initiation
AD	0003677	molecular_function	DNA binding
AD	0003684	molecular_function	damaged DNA binding
AD	0003723	molecular_function	RNA binding
AD	0003729	molecular_function	mRNA binding
AD	0003735	molecular_function	structural constituent of ribosome
AD	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
AD	0004520	molecular_function	DNA endonuclease activity
AD	0005515	molecular_function	protein binding
AD	0005634	cellular_component	nucleus
AD	0005654	cellular_component	nucleoplasm
AD	0005730	cellular_component	nucleolus
AD	0005737	cellular_component	cytoplasm
AD	0005743	cellular_component	mitochondrial inner membrane
AD	0005759	cellular_component	mitochondrial matrix
AD	0005783	cellular_component	endoplasmic reticulum
AD	0005819	cellular_component	spindle
AD	0005829	cellular_component	cytosol
AD	0005840	cellular_component	ribosome
AD	0005886	cellular_component	plasma membrane
AD	0005925	cellular_component	focal adhesion
AD	0006281	biological_process	DNA repair
AD	0006284	biological_process	base-excision repair
AD	0006351	biological_process	DNA-templated transcription
AD	0006412	biological_process	translation
AD	0006417	biological_process	regulation of translation
AD	0006915	biological_process	apoptotic process
AD	0006974	biological_process	DNA damage response
AD	0007059	biological_process	chromosome segregation
AD	0008017	molecular_function	microtubule binding
AD	0010628	biological_process	positive regulation of gene expression
AD	0014069	cellular_component	postsynaptic density
AD	0015631	molecular_function	tubulin binding
AD	0015935	cellular_component	small ribosomal subunit
AD	0016020	cellular_component	membrane
AD	0016829	molecular_function	lyase activity
AD	0017148	biological_process	negative regulation of translation
AD	0019104	molecular_function	DNA N-glycosylase activity
AD	0019899	molecular_function	enzyme binding
AD	0019900	molecular_function	kinase binding
AD	0019901	molecular_function	protein kinase binding
AD	0022626	cellular_component	cytosolic ribosome
AD	0022627	cellular_component	cytosolic small ribosomal subunit
AD	0030544	molecular_function	Hsp70 protein binding
AD	0031116	biological_process	positive regulation of microtubule polymerization
AD	0031397	biological_process	negative regulation of protein ubiquitination
AD	0032357	molecular_function	oxidized purine DNA binding
AD	0032358	molecular_function	oxidized pyrimidine DNA binding
AD	0032587	cellular_component	ruffle membrane
AD	0034614	biological_process	cellular response to reactive oxygen species
AD	0042981	biological_process	regulation of apoptotic process
AD	0044390	molecular_function	ubiquitin-like protein conjugating enzyme binding
AD	0045202	cellular_component	synapse
AD	0045738	biological_process	negative regulation of DNA repair
AD	0045739	biological_process	positive regulation of DNA repair
AD	0045944	biological_process	positive regulation of transcription by RNA polymerase II
AD	0051018	molecular_function	protein kinase A binding
AD	0051225	biological_process	spindle assembly
AD	0051301	biological_process	cell division
AD	0051536	molecular_function	iron-sulfur cluster binding
AD	0051879	molecular_function	Hsp90 protein binding
AD	0061481	biological_process	response to TNF agonist
AD	0070062	cellular_component	extracellular exosome
AD	0070181	molecular_function	small ribosomal subunit rRNA binding
AD	0070301	biological_process	cellular response to hydrogen peroxide
AD	0071159	cellular_component	NF-kappaB complex
AD	0072686	cellular_component	mitotic spindle
AD	0097100	molecular_function	supercoiled DNA binding
AD	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AD	0140297	molecular_function	DNA-binding transcription factor binding
AD	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
AD	1902231	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
AD	1905053	biological_process	positive regulation of base-excision repair
AD	1990904	cellular_component	ribonucleoprotein complex
AD	2000144	biological_process	positive regulation of DNA-templated transcription initiation
AD	2001235	biological_process	positive regulation of apoptotic signaling pathway
Ae	0002181	biological_process	cytoplasmic translation
Ae	0002227	biological_process	innate immune response in mucosa
Ae	0003723	molecular_function	RNA binding
Ae	0003735	molecular_function	structural constituent of ribosome
Ae	0005515	molecular_function	protein binding
Ae	0005615	cellular_component	extracellular space
Ae	0005634	cellular_component	nucleus
Ae	0005654	cellular_component	nucleoplasm
Ae	0005730	cellular_component	nucleolus
Ae	0005737	cellular_component	cytoplasm
Ae	0005783	cellular_component	endoplasmic reticulum
Ae	0005829	cellular_component	cytosol
Ae	0005840	cellular_component	ribosome
Ae	0006412	biological_process	translation
Ae	0015935	cellular_component	small ribosomal subunit
Ae	0016567	biological_process	protein ubiquitination
Ae	0019731	biological_process	antibacterial humoral response
Ae	0019941	biological_process	modification-dependent protein catabolic process
Ae	0022626	cellular_component	cytosolic ribosome
Ae	0022627	cellular_component	cytosolic small ribosomal subunit
Ae	0031386	molecular_function	protein tag activity
Ae	0050830	biological_process	defense response to Gram-positive bacterium
Ae	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
Ae	1990904	cellular_component	ribonucleoprotein complex
AE	0002181	biological_process	cytoplasmic translation
AE	0003723	molecular_function	RNA binding
AE	0003735	molecular_function	structural constituent of ribosome
AE	0005515	molecular_function	protein binding
AE	0005654	cellular_component	nucleoplasm
AE	0005730	cellular_component	nucleolus
AE	0005737	cellular_component	cytoplasm
AE	0005829	cellular_component	cytosol
AE	0005840	cellular_component	ribosome
AE	0005925	cellular_component	focal adhesion
AE	0006412	biological_process	translation
AE	0008284	biological_process	positive regulation of cell population proliferation
AE	0015935	cellular_component	small ribosomal subunit
AE	0016020	cellular_component	membrane
AE	0019843	molecular_function	rRNA binding
AE	0022626	cellular_component	cytosolic ribosome
AE	0022627	cellular_component	cytosolic small ribosomal subunit
AE	0032040	cellular_component	small-subunit processome
AE	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
AE	0042274	biological_process	ribosomal small subunit biogenesis
AE	0045727	biological_process	positive regulation of translation
AE	0070062	cellular_component	extracellular exosome
AE	1990904	cellular_component	ribonucleoprotein complex
Af	0002181	biological_process	cytoplasmic translation
Af	0003723	molecular_function	RNA binding
Af	0003735	molecular_function	structural constituent of ribosome
Af	0005515	molecular_function	protein binding
Af	0005615	cellular_component	extracellular space
Af	0005634	cellular_component	nucleus
Af	0005654	cellular_component	nucleoplasm
Af	0005730	cellular_component	nucleolus
Af	0005737	cellular_component	cytoplasm
Af	0005741	cellular_component	mitochondrial outer membrane
Af	0005783	cellular_component	endoplasmic reticulum
Af	0005789	cellular_component	endoplasmic reticulum membrane
Af	0005829	cellular_component	cytosol
Af	0005840	cellular_component	ribosome
Af	0005886	cellular_component	plasma membrane
Af	0006412	biological_process	translation
Af	0008270	molecular_function	zinc ion binding
Af	0010008	cellular_component	endosome membrane
Af	0016020	cellular_component	membrane
Af	0016567	biological_process	protein ubiquitination
Af	0019941	biological_process	modification-dependent protein catabolic process
Af	0022626	cellular_component	cytosolic ribosome
Af	0030666	cellular_component	endocytic vesicle membrane
Af	0031386	molecular_function	protein tag activity
Af	0031982	cellular_component	vesicle
Af	0032040	cellular_component	small-subunit processome
Af	0045202	cellular_component	synapse
Af	0046872	molecular_function	metal ion binding
Af	0070062	cellular_component	extracellular exosome
Af	1990904	cellular_component	ribonucleoprotein complex
AF	0002181	biological_process	cytoplasmic translation
AF	0003723	molecular_function	RNA binding
AF	0003729	molecular_function	mRNA binding
AF	0003735	molecular_function	structural constituent of ribosome
AF	0005515	molecular_function	protein binding
AF	0005654	cellular_component	nucleoplasm
AF	0005730	cellular_component	nucleolus
AF	0005737	cellular_component	cytoplasm
AF	0005783	cellular_component	endoplasmic reticulum
AF	0005829	cellular_component	cytosol
AF	0005840	cellular_component	ribosome
AF	0005925	cellular_component	focal adhesion
AF	0006412	biological_process	translation
AF	0006413	biological_process	translational initiation
AF	0006450	biological_process	regulation of translational fidelity
AF	0015935	cellular_component	small ribosomal subunit
AF	0016020	cellular_component	membrane
AF	0019843	molecular_function	rRNA binding
AF	0022626	cellular_component	cytosolic ribosome
AF	0022627	cellular_component	cytosolic small ribosomal subunit
AF	0032040	cellular_component	small-subunit processome
AF	0042274	biological_process	ribosomal small subunit biogenesis
AF	0045202	cellular_component	synapse
AF	0070062	cellular_component	extracellular exosome
AF	1990904	cellular_component	ribonucleoprotein complex
Ag	0001891	cellular_component	phagocytic cup
Ag	0001934	biological_process	positive regulation of protein phosphorylation
Ag	0002181	biological_process	cytoplasmic translation
Ag	0003723	molecular_function	RNA binding
Ag	0005080	molecular_function	protein kinase C binding
Ag	0005102	molecular_function	signaling receptor binding
Ag	0005515	molecular_function	protein binding
Ag	0005634	cellular_component	nucleus
Ag	0005654	cellular_component	nucleoplasm
Ag	0005737	cellular_component	cytoplasm
Ag	0005739	cellular_component	mitochondrion
Ag	0005829	cellular_component	cytosol
Ag	0005840	cellular_component	ribosome
Ag	0005886	cellular_component	plasma membrane
Ag	0006417	biological_process	regulation of translation
Ag	0006915	biological_process	apoptotic process
Ag	0007369	biological_process	gastrulation
Ag	0008047	molecular_function	enzyme activator activity
Ag	0008200	molecular_function	ion channel inhibitor activity
Ag	0008656	molecular_function	cysteine-type endopeptidase activator activity involved in apoptotic process
Ag	0010629	biological_process	negative regulation of gene expression
Ag	0015935	cellular_component	small ribosomal subunit
Ag	0016567	biological_process	protein ubiquitination
Ag	0017148	biological_process	negative regulation of translation
Ag	0019899	molecular_function	enzyme binding
Ag	0019903	molecular_function	protein phosphatase binding
Ag	0030178	biological_process	negative regulation of Wnt signaling pathway
Ag	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
Ag	0030292	molecular_function	protein tyrosine kinase inhibitor activity
Ag	0030308	biological_process	negative regulation of cell growth
Ag	0030332	molecular_function	cyclin binding
Ag	0030335	biological_process	positive regulation of cell migration
Ag	0030425	cellular_component	dendrite
Ag	0030496	cellular_component	midbody
Ag	0030971	molecular_function	receptor tyrosine kinase binding
Ag	0031334	biological_process	positive regulation of protein-containing complex assembly
Ag	0032091	biological_process	negative regulation of protein binding
Ag	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Ag	0032880	biological_process	regulation of protein localization
Ag	0035591	molecular_function	signaling adaptor activity
Ag	0042169	molecular_function	SH2 domain binding
Ag	0042802	molecular_function	identical protein binding
Ag	0042803	molecular_function	protein homodimerization activity
Ag	0042998	biological_process	positive regulation of Golgi to plasma membrane protein transport
Ag	0043005	cellular_component	neuron projection
Ag	0043022	molecular_function	ribosome binding
Ag	0043025	cellular_component	neuronal cell body
Ag	0043065	biological_process	positive regulation of apoptotic process
Ag	0043204	cellular_component	perikaryon
Ag	0043547	biological_process	positive regulation of GTPase activity
Ag	0044297	cellular_component	cell body
Ag	0045182	molecular_function	translation regulator activity
Ag	0045296	molecular_function	cadherin binding
Ag	0045879	biological_process	negative regulation of smoothened signaling pathway
Ag	0048471	cellular_component	perinuclear region of cytoplasm
Ag	0048511	biological_process	rhythmic process
Ag	0050765	biological_process	negative regulation of phagocytosis
Ag	0051302	biological_process	regulation of cell division
Ag	0051434	molecular_function	BH3 domain binding
Ag	0051726	biological_process	regulation of cell cycle
Ag	0051898	biological_process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Ag	0051901	biological_process	positive regulation of mitochondrial depolarization
Ag	0060090	molecular_function	molecular adaptor activity
Ag	0070062	cellular_component	extracellular exosome
Ag	0071333	biological_process	cellular response to glucose stimulus
Ag	0071363	biological_process	cellular response to growth factor stimulus
Ag	0072344	biological_process	rescue of stalled ribosome
Ag	0106070	biological_process	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
Ag	1900102	biological_process	negative regulation of endoplasmic reticulum unfolded protein response
Ag	1903751	biological_process	negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
Ag	1990630	cellular_component	IRE1-RACK1-PP2A complex
Ag	1990904	cellular_component	ribonucleoprotein complex
Ag	2000114	biological_process	regulation of establishment of cell polarity
Ag	2000543	biological_process	positive regulation of gastrulation
Ag	2001125	biological_process	negative regulation of translational frameshifting
Ag	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
AG	0000028	biological_process	ribosomal small subunit assembly
AG	0002181	biological_process	cytoplasmic translation
AG	0003723	molecular_function	RNA binding
AG	0003729	molecular_function	mRNA binding
AG	0003735	molecular_function	structural constituent of ribosome
AG	0005515	molecular_function	protein binding
AG	0005634	cellular_component	nucleus
AG	0005654	cellular_component	nucleoplasm
AG	0005730	cellular_component	nucleolus
AG	0005737	cellular_component	cytoplasm
AG	0005783	cellular_component	endoplasmic reticulum
AG	0005829	cellular_component	cytosol
AG	0005840	cellular_component	ribosome
AG	0006364	biological_process	rRNA processing
AG	0006412	biological_process	translation
AG	0008284	biological_process	positive regulation of cell population proliferation
AG	0015935	cellular_component	small ribosomal subunit
AG	0016020	cellular_component	membrane
AG	0019901	molecular_function	protein kinase binding
AG	0022626	cellular_component	cytosolic ribosome
AG	0022627	cellular_component	cytosolic small ribosomal subunit
AG	0030425	cellular_component	dendrite
AG	0031929	biological_process	TOR signaling
AG	0032040	cellular_component	small-subunit processome
AG	0032868	biological_process	response to insulin
AG	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
AG	0042274	biological_process	ribosomal small subunit biogenesis
AG	0042593	biological_process	glucose homeostasis
AG	0043065	biological_process	positive regulation of apoptotic process
AG	0044297	cellular_component	cell body
AG	0071361	biological_process	cellular response to ethanol
AG	0098793	cellular_component	presynapse
AG	0098982	cellular_component	GABA-ergic synapse
AG	1903347	biological_process	negative regulation of bicellular tight junction assembly
AG	1990904	cellular_component	ribonucleoprotein complex
Ah	0002181	biological_process	cytoplasmic translation
Ah	0003723	molecular_function	RNA binding
Ah	0003730	molecular_function	mRNA 3'-UTR binding
Ah	0003735	molecular_function	structural constituent of ribosome
Ah	0005515	molecular_function	protein binding
Ah	0005737	cellular_component	cytoplasm
Ah	0005783	cellular_component	endoplasmic reticulum
Ah	0005829	cellular_component	cytosol
Ah	0005840	cellular_component	ribosome
Ah	0006412	biological_process	translation
Ah	0006941	biological_process	striated muscle contraction
Ah	0007283	biological_process	spermatogenesis
Ah	0022625	cellular_component	cytosolic large ribosomal subunit
Ah	0048027	molecular_function	mRNA 5'-UTR binding
Ah	1901740	biological_process	negative regulation of myoblast fusion
Ah	1990904	cellular_component	ribonucleoprotein complex
AH	0002181	biological_process	cytoplasmic translation
AH	0003723	molecular_function	RNA binding
AH	0003730	molecular_function	mRNA 3'-UTR binding
AH	0003735	molecular_function	structural constituent of ribosome
AH	0005515	molecular_function	protein binding
AH	0005634	cellular_component	nucleus
AH	0005654	cellular_component	nucleoplasm
AH	0005730	cellular_component	nucleolus
AH	0005737	cellular_component	cytoplasm
AH	0005813	cellular_component	centrosome
AH	0005829	cellular_component	cytosol
AH	0005840	cellular_component	ribosome
AH	0005925	cellular_component	focal adhesion
AH	0006364	biological_process	rRNA processing
AH	0006412	biological_process	translation
AH	0016020	cellular_component	membrane
AH	0019901	molecular_function	protein kinase binding
AH	0022626	cellular_component	cytosolic ribosome
AH	0022627	cellular_component	cytosolic small ribosomal subunit
AH	0032040	cellular_component	small-subunit processome
AH	0032991	cellular_component	protein-containing complex
AH	0042274	biological_process	ribosomal small subunit biogenesis
AH	0045202	cellular_component	synapse
AH	0048027	molecular_function	mRNA 5'-UTR binding
AH	1902255	biological_process	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
AH	1990904	cellular_component	ribonucleoprotein complex
AH	1990948	molecular_function	ubiquitin ligase inhibitor activity
AH	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
AI	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AI	0002181	biological_process	cytoplasmic translation
AI	0003723	molecular_function	RNA binding
AI	0003735	molecular_function	structural constituent of ribosome
AI	0005515	molecular_function	protein binding
AI	0005634	cellular_component	nucleus
AI	0005654	cellular_component	nucleoplasm
AI	0005730	cellular_component	nucleolus
AI	0005737	cellular_component	cytoplasm
AI	0005783	cellular_component	endoplasmic reticulum
AI	0005829	cellular_component	cytosol
AI	0005840	cellular_component	ribosome
AI	0005925	cellular_component	focal adhesion
AI	0006412	biological_process	translation
AI	0016020	cellular_component	membrane
AI	0022626	cellular_component	cytosolic ribosome
AI	0022627	cellular_component	cytosolic small ribosomal subunit
AI	0032040	cellular_component	small-subunit processome
AI	0042274	biological_process	ribosomal small subunit biogenesis
AI	0070062	cellular_component	extracellular exosome
AI	1990904	cellular_component	ribonucleoprotein complex
AJ	0002181	biological_process	cytoplasmic translation
AJ	0003723	molecular_function	RNA binding
AJ	0003735	molecular_function	structural constituent of ribosome
AJ	0005515	molecular_function	protein binding
AJ	0005634	cellular_component	nucleus
AJ	0005654	cellular_component	nucleoplasm
AJ	0005730	cellular_component	nucleolus
AJ	0005737	cellular_component	cytoplasm
AJ	0005829	cellular_component	cytosol
AJ	0005840	cellular_component	ribosome
AJ	0005925	cellular_component	focal adhesion
AJ	0006412	biological_process	translation
AJ	0015935	cellular_component	small ribosomal subunit
AJ	0016020	cellular_component	membrane
AJ	0019843	molecular_function	rRNA binding
AJ	0022626	cellular_component	cytosolic ribosome
AJ	0022627	cellular_component	cytosolic small ribosomal subunit
AJ	0032040	cellular_component	small-subunit processome
AJ	0042274	biological_process	ribosomal small subunit biogenesis
AJ	0045202	cellular_component	synapse
AJ	0070062	cellular_component	extracellular exosome
AJ	1990904	cellular_component	ribonucleoprotein complex
AK	0002181	biological_process	cytoplasmic translation
AK	0003723	molecular_function	RNA binding
AK	0003735	molecular_function	structural constituent of ribosome
AK	0005515	molecular_function	protein binding
AK	0005654	cellular_component	nucleoplasm
AK	0005730	cellular_component	nucleolus
AK	0005737	cellular_component	cytoplasm
AK	0005829	cellular_component	cytosol
AK	0005840	cellular_component	ribosome
AK	0005925	cellular_component	focal adhesion
AK	0006412	biological_process	translation
AK	0016020	cellular_component	membrane
AK	0022626	cellular_component	cytosolic ribosome
AK	0022627	cellular_component	cytosolic small ribosomal subunit
AK	0045202	cellular_component	synapse
AK	1990904	cellular_component	ribonucleoprotein complex
AL	0002181	biological_process	cytoplasmic translation
AL	0003723	molecular_function	RNA binding
AL	0003735	molecular_function	structural constituent of ribosome
AL	0005515	molecular_function	protein binding
AL	0005654	cellular_component	nucleoplasm
AL	0005730	cellular_component	nucleolus
AL	0005737	cellular_component	cytoplasm
AL	0005829	cellular_component	cytosol
AL	0005840	cellular_component	ribosome
AL	0005925	cellular_component	focal adhesion
AL	0006412	biological_process	translation
AL	0016020	cellular_component	membrane
AL	0019843	molecular_function	rRNA binding
AL	0022626	cellular_component	cytosolic ribosome
AL	0022627	cellular_component	cytosolic small ribosomal subunit
AL	0032040	cellular_component	small-subunit processome
AL	0042274	biological_process	ribosomal small subunit biogenesis
AL	0045202	cellular_component	synapse
AL	0070062	cellular_component	extracellular exosome
AL	1990904	cellular_component	ribonucleoprotein complex
AM	0002181	biological_process	cytoplasmic translation
AM	0003723	molecular_function	RNA binding
AM	0003735	molecular_function	structural constituent of ribosome
AM	0005515	molecular_function	protein binding
AM	0005654	cellular_component	nucleoplasm
AM	0005730	cellular_component	nucleolus
AM	0005737	cellular_component	cytoplasm
AM	0005829	cellular_component	cytosol
AM	0005840	cellular_component	ribosome
AM	0006412	biological_process	translation
AM	0016020	cellular_component	membrane
AM	0022626	cellular_component	cytosolic ribosome
AM	0022627	cellular_component	cytosolic small ribosomal subunit
AM	0032040	cellular_component	small-subunit processome
AM	0042274	biological_process	ribosomal small subunit biogenesis
AM	0090263	biological_process	positive regulation of canonical Wnt signaling pathway
AM	1990145	biological_process	maintenance of translational fidelity
AM	1990904	cellular_component	ribonucleoprotein complex
AN	0002181	biological_process	cytoplasmic translation
AN	0003723	molecular_function	RNA binding
AN	0003729	molecular_function	mRNA binding
AN	0003735	molecular_function	structural constituent of ribosome
AN	0005515	molecular_function	protein binding
AN	0005634	cellular_component	nucleus
AN	0005654	cellular_component	nucleoplasm
AN	0005730	cellular_component	nucleolus
AN	0005737	cellular_component	cytoplasm
AN	0005829	cellular_component	cytosol
AN	0005840	cellular_component	ribosome
AN	0005925	cellular_component	focal adhesion
AN	0006412	biological_process	translation
AN	0014069	cellular_component	postsynaptic density
AN	0016020	cellular_component	membrane
AN	0022626	cellular_component	cytosolic ribosome
AN	0022627	cellular_component	cytosolic small ribosomal subunit
AN	0032040	cellular_component	small-subunit processome
AN	0033119	biological_process	negative regulation of RNA splicing
AN	0042274	biological_process	ribosomal small subunit biogenesis
AN	0048027	molecular_function	mRNA 5'-UTR binding
AN	0070062	cellular_component	extracellular exosome
AN	0070181	molecular_function	small ribosomal subunit rRNA binding
AN	1990904	cellular_component	ribonucleoprotein complex
AO	0000028	biological_process	ribosomal small subunit assembly
AO	0000122	biological_process	negative regulation of transcription by RNA polymerase II
AO	0002181	biological_process	cytoplasmic translation
AO	0003723	molecular_function	RNA binding
AO	0003735	molecular_function	structural constituent of ribosome
AO	0005515	molecular_function	protein binding
AO	0005654	cellular_component	nucleoplasm
AO	0005730	cellular_component	nucleolus
AO	0005737	cellular_component	cytoplasm
AO	0005783	cellular_component	endoplasmic reticulum
AO	0005829	cellular_component	cytosol
AO	0005840	cellular_component	ribosome
AO	0005925	cellular_component	focal adhesion
AO	0006412	biological_process	translation
AO	0014069	cellular_component	postsynaptic density
AO	0016020	cellular_component	membrane
AO	0022626	cellular_component	cytosolic ribosome
AO	0022627	cellular_component	cytosolic small ribosomal subunit
AO	0030218	biological_process	erythrocyte differentiation
AO	0030490	biological_process	maturation of SSU-rRNA
AO	0032040	cellular_component	small-subunit processome
AO	0042274	biological_process	ribosomal small subunit biogenesis
AO	0045202	cellular_component	synapse
AO	0048027	molecular_function	mRNA 5'-UTR binding
AO	0070062	cellular_component	extracellular exosome
AO	1990904	cellular_component	ribonucleoprotein complex
AP	0000028	biological_process	ribosomal small subunit assembly
AP	0000056	biological_process	ribosomal small subunit export from nucleus
AP	0001649	biological_process	osteoblast differentiation
AP	0002181	biological_process	cytoplasmic translation
AP	0003677	molecular_function	DNA binding
AP	0003723	molecular_function	RNA binding
AP	0003735	molecular_function	structural constituent of ribosome
AP	0005515	molecular_function	protein binding
AP	0005634	cellular_component	nucleus
AP	0005654	cellular_component	nucleoplasm
AP	0005737	cellular_component	cytoplasm
AP	0005829	cellular_component	cytosol
AP	0005840	cellular_component	ribosome
AP	0005925	cellular_component	focal adhesion
AP	0006364	biological_process	rRNA processing
AP	0006412	biological_process	translation
AP	0015935	cellular_component	small ribosomal subunit
AP	0016020	cellular_component	membrane
AP	0022626	cellular_component	cytosolic ribosome
AP	0022627	cellular_component	cytosolic small ribosomal subunit
AP	0042274	biological_process	ribosomal small subunit biogenesis
AP	0045202	cellular_component	synapse
AP	0097371	molecular_function	MDM2/MDM4 family protein binding
AP	0097421	biological_process	liver regeneration
AP	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
AP	1990904	cellular_component	ribonucleoprotein complex
AP	1990948	molecular_function	ubiquitin ligase inhibitor activity
AQ	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AQ	0002181	biological_process	cytoplasmic translation
AQ	0003723	molecular_function	RNA binding
AQ	0003735	molecular_function	structural constituent of ribosome
AQ	0005515	molecular_function	protein binding
AQ	0005654	cellular_component	nucleoplasm
AQ	0005730	cellular_component	nucleolus
AQ	0005737	cellular_component	cytoplasm
AQ	0005783	cellular_component	endoplasmic reticulum
AQ	0005829	cellular_component	cytosol
AQ	0005840	cellular_component	ribosome
AQ	0005925	cellular_component	focal adhesion
AQ	0006364	biological_process	rRNA processing
AQ	0006412	biological_process	translation
AQ	0015935	cellular_component	small ribosomal subunit
AQ	0016020	cellular_component	membrane
AQ	0022626	cellular_component	cytosolic ribosome
AQ	0022627	cellular_component	cytosolic small ribosomal subunit
AQ	0032040	cellular_component	small-subunit processome
AQ	0042274	biological_process	ribosomal small subunit biogenesis
AQ	0045202	cellular_component	synapse
AQ	0070062	cellular_component	extracellular exosome
AQ	1990904	cellular_component	ribonucleoprotein complex
AR	0002181	biological_process	cytoplasmic translation
AR	0003723	molecular_function	RNA binding
AR	0003735	molecular_function	structural constituent of ribosome
AR	0005654	cellular_component	nucleoplasm
AR	0005730	cellular_component	nucleolus
AR	0005737	cellular_component	cytoplasm
AR	0005829	cellular_component	cytosol
AR	0005840	cellular_component	ribosome
AR	0005925	cellular_component	focal adhesion
AR	0006364	biological_process	rRNA processing
AR	0006412	biological_process	translation
AR	0006413	biological_process	translational initiation
AR	0016020	cellular_component	membrane
AR	0022626	cellular_component	cytosolic ribosome
AR	0022627	cellular_component	cytosolic small ribosomal subunit
AR	0032040	cellular_component	small-subunit processome
AR	0034101	biological_process	erythrocyte homeostasis
AR	0042274	biological_process	ribosomal small subunit biogenesis
AR	1990904	cellular_component	ribonucleoprotein complex
AS	0002181	biological_process	cytoplasmic translation
AS	0003676	molecular_function	nucleic acid binding
AS	0003723	molecular_function	RNA binding
AS	0003735	molecular_function	structural constituent of ribosome
AS	0005515	molecular_function	protein binding
AS	0005634	cellular_component	nucleus
AS	0005654	cellular_component	nucleoplasm
AS	0005737	cellular_component	cytoplasm
AS	0005829	cellular_component	cytosol
AS	0005840	cellular_component	ribosome
AS	0005925	cellular_component	focal adhesion
AS	0006412	biological_process	translation
AS	0014069	cellular_component	postsynaptic density
AS	0015935	cellular_component	small ribosomal subunit
AS	0016020	cellular_component	membrane
AS	0019843	molecular_function	rRNA binding
AS	0022626	cellular_component	cytosolic ribosome
AS	0022627	cellular_component	cytosolic small ribosomal subunit
AS	0045202	cellular_component	synapse
AS	0070062	cellular_component	extracellular exosome
AS	1990904	cellular_component	ribonucleoprotein complex
AT	0000028	biological_process	ribosomal small subunit assembly
AT	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AT	0002181	biological_process	cytoplasmic translation
AT	0002548	biological_process	monocyte chemotaxis
AT	0003723	molecular_function	RNA binding
AT	0003735	molecular_function	structural constituent of ribosome
AT	0005515	molecular_function	protein binding
AT	0005654	cellular_component	nucleoplasm
AT	0005730	cellular_component	nucleolus
AT	0005737	cellular_component	cytoplasm
AT	0005829	cellular_component	cytosol
AT	0005840	cellular_component	ribosome
AT	0005925	cellular_component	focal adhesion
AT	0006364	biological_process	rRNA processing
AT	0006412	biological_process	translation
AT	0007000	biological_process	nucleolus organization
AT	0014069	cellular_component	postsynaptic density
AT	0016020	cellular_component	membrane
AT	0017134	molecular_function	fibroblast growth factor binding
AT	0022626	cellular_component	cytosolic ribosome
AT	0022627	cellular_component	cytosolic small ribosomal subunit
AT	0030218	biological_process	erythrocyte differentiation
AT	0030490	biological_process	maturation of SSU-rRNA
AT	0031640	biological_process	killing of cells of another organism
AT	0032040	cellular_component	small-subunit processome
AT	0042274	biological_process	ribosomal small subunit biogenesis
AT	0042802	molecular_function	identical protein binding
AT	0050829	biological_process	defense response to Gram-negative bacterium
AT	0060265	biological_process	positive regulation of respiratory burst involved in inflammatory response
AT	0060266	biological_process	negative regulation of respiratory burst involved in inflammatory response
AT	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
AT	0070062	cellular_component	extracellular exosome
AT	1990904	cellular_component	ribonucleoprotein complex
AU	0002181	biological_process	cytoplasmic translation
AU	0003723	molecular_function	RNA binding
AU	0003735	molecular_function	structural constituent of ribosome
AU	0005515	molecular_function	protein binding
AU	0005654	cellular_component	nucleoplasm
AU	0005737	cellular_component	cytoplasm
AU	0005783	cellular_component	endoplasmic reticulum
AU	0005829	cellular_component	cytosol
AU	0005840	cellular_component	ribosome
AU	0006412	biological_process	translation
AU	0015935	cellular_component	small ribosomal subunit
AU	0016020	cellular_component	membrane
AU	0022626	cellular_component	cytosolic ribosome
AU	0022627	cellular_component	cytosolic small ribosomal subunit
AU	0045202	cellular_component	synapse
AU	0070062	cellular_component	extracellular exosome
AU	0097371	molecular_function	MDM2/MDM4 family protein binding
AU	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
AU	1990904	cellular_component	ribonucleoprotein complex
AU	1990948	molecular_function	ubiquitin ligase inhibitor activity
AV	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AV	0000461	biological_process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AV	0002181	biological_process	cytoplasmic translation
AV	0003723	molecular_function	RNA binding
AV	0003735	molecular_function	structural constituent of ribosome
AV	0005515	molecular_function	protein binding
AV	0005654	cellular_component	nucleoplasm
AV	0005737	cellular_component	cytoplasm
AV	0005791	cellular_component	rough endoplasmic reticulum
AV	0005829	cellular_component	cytosol
AV	0005840	cellular_component	ribosome
AV	0006412	biological_process	translation
AV	0015935	cellular_component	small ribosomal subunit
AV	0022626	cellular_component	cytosolic ribosome
AV	0022627	cellular_component	cytosolic small ribosomal subunit
AV	0045202	cellular_component	synapse
AV	1990904	cellular_component	ribonucleoprotein complex
AW	0002181	biological_process	cytoplasmic translation
AW	0003723	molecular_function	RNA binding
AW	0003735	molecular_function	structural constituent of ribosome
AW	0005515	molecular_function	protein binding
AW	0005654	cellular_component	nucleoplasm
AW	0005730	cellular_component	nucleolus
AW	0005737	cellular_component	cytoplasm
AW	0005829	cellular_component	cytosol
AW	0005840	cellular_component	ribosome
AW	0006412	biological_process	translation
AW	0008284	biological_process	positive regulation of cell population proliferation
AW	0009615	biological_process	response to virus
AW	0016020	cellular_component	membrane
AW	0022626	cellular_component	cytosolic ribosome
AW	0022627	cellular_component	cytosolic small ribosomal subunit
AW	0032040	cellular_component	small-subunit processome
AW	0042274	biological_process	ribosomal small subunit biogenesis
AW	0045787	biological_process	positive regulation of cell cycle
AW	0070062	cellular_component	extracellular exosome
AW	1990904	cellular_component	ribonucleoprotein complex
AX	0003735	molecular_function	structural constituent of ribosome
AX	0005791	cellular_component	rough endoplasmic reticulum
AX	0005840	cellular_component	ribosome
AX	0006412	biological_process	translation
AX	0015935	cellular_component	small ribosomal subunit
AX	0022626	cellular_component	cytosolic ribosome
AX	1990904	cellular_component	ribonucleoprotein complex
AY	0002181	biological_process	cytoplasmic translation
AY	0003723	molecular_function	RNA binding
AY	0003735	molecular_function	structural constituent of ribosome
AY	0005515	molecular_function	protein binding
AY	0005634	cellular_component	nucleus
AY	0005654	cellular_component	nucleoplasm
AY	0005730	cellular_component	nucleolus
AY	0005737	cellular_component	cytoplasm
AY	0005783	cellular_component	endoplasmic reticulum
AY	0005829	cellular_component	cytosol
AY	0005840	cellular_component	ribosome
AY	0006364	biological_process	rRNA processing
AY	0006412	biological_process	translation
AY	0015935	cellular_component	small ribosomal subunit
AY	0016020	cellular_component	membrane
AY	0022626	cellular_component	cytosolic ribosome
AY	0022627	cellular_component	cytosolic small ribosomal subunit
AY	0031369	molecular_function	translation initiation factor binding
AY	0032040	cellular_component	small-subunit processome
AY	0034101	biological_process	erythrocyte homeostasis
AY	0042274	biological_process	ribosomal small subunit biogenesis
AY	1990904	cellular_component	ribonucleoprotein complex
AZ	0002181	biological_process	cytoplasmic translation
AZ	0003723	molecular_function	RNA binding
AZ	0003735	molecular_function	structural constituent of ribosome
AZ	0005515	molecular_function	protein binding
AZ	0005634	cellular_component	nucleus
AZ	0005654	cellular_component	nucleoplasm
AZ	0005730	cellular_component	nucleolus
AZ	0005737	cellular_component	cytoplasm
AZ	0005783	cellular_component	endoplasmic reticulum
AZ	0005829	cellular_component	cytosol
AZ	0005840	cellular_component	ribosome
AZ	0006364	biological_process	rRNA processing
AZ	0006412	biological_process	translation
AZ	0014069	cellular_component	postsynaptic density
AZ	0015935	cellular_component	small ribosomal subunit
AZ	0022626	cellular_component	cytosolic ribosome
AZ	0022627	cellular_component	cytosolic small ribosomal subunit
AZ	0042274	biological_process	ribosomal small subunit biogenesis
AZ	0045202	cellular_component	synapse
AZ	0070062	cellular_component	extracellular exosome
AZ	1990904	cellular_component	ribonucleoprotein complex
I3	0001732	biological_process	formation of cytoplasmic translation initiation complex
I3	0002183	biological_process	cytoplasmic translational initiation
I3	0003723	molecular_function	RNA binding
I3	0003743	molecular_function	translation initiation factor activity
I3	0005515	molecular_function	protein binding
I3	0005634	cellular_component	nucleus
I3	0005737	cellular_component	cytoplasm
I3	0005829	cellular_component	cytosol
I3	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
I3	0006412	biological_process	translation
I3	0006413	biological_process	translational initiation
I3	0006446	biological_process	regulation of translational initiation
I3	0016020	cellular_component	membrane
I3	0016282	cellular_component	eukaryotic 43S preinitiation complex
I3	0033290	cellular_component	eukaryotic 48S preinitiation complex
I3	0043022	molecular_function	ribosome binding
I4	0001732	biological_process	formation of cytoplasmic translation initiation complex
I4	0002183	biological_process	cytoplasmic translational initiation
I4	0003743	molecular_function	translation initiation factor activity
I4	0004843	molecular_function	cysteine-type deubiquitinase activity
I4	0005515	molecular_function	protein binding
I4	0005737	cellular_component	cytoplasm
I4	0005829	cellular_component	cytosol
I4	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
I4	0006412	biological_process	translation
I4	0006413	biological_process	translational initiation
I4	0006508	biological_process	proteolysis
I4	0008233	molecular_function	peptidase activity
I4	0008234	molecular_function	cysteine-type peptidase activity
I4	0008237	molecular_function	metallopeptidase activity
I4	0016020	cellular_component	membrane
I4	0016282	cellular_component	eukaryotic 43S preinitiation complex
I4	0016787	molecular_function	hydrolase activity
I4	0031369	molecular_function	translation initiation factor binding
I4	0033290	cellular_component	eukaryotic 48S preinitiation complex
I4	0042802	molecular_function	identical protein binding
I4	0045202	cellular_component	synapse
I4	0071541	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3m
I4	0075522	biological_process	IRES-dependent viral translational initiation
I4	0101005	molecular_function	deubiquitinase activity
I4	0140492	molecular_function	metal-dependent deubiquitinase activity
I5	0001650	cellular_component	fibrillar center
I5	0001732	biological_process	formation of cytoplasmic translation initiation complex
I5	0002183	biological_process	cytoplasmic translational initiation
I5	0003723	molecular_function	RNA binding
I5	0003743	molecular_function	translation initiation factor activity
I5	0005515	molecular_function	protein binding
I5	0005654	cellular_component	nucleoplasm
I5	0005730	cellular_component	nucleolus
I5	0005737	cellular_component	cytoplasm
I5	0005829	cellular_component	cytosol
I5	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
I5	0006412	biological_process	translation
I5	0006413	biological_process	translational initiation
I5	0016020	cellular_component	membrane
I5	0016282	cellular_component	eukaryotic 43S preinitiation complex
I5	0032991	cellular_component	protein-containing complex
I5	0033290	cellular_component	eukaryotic 48S preinitiation complex
I5	0045202	cellular_component	synapse
I5	0075525	biological_process	viral translational termination-reinitiation
I6	0001732	biological_process	formation of cytoplasmic translation initiation complex
I6	0002183	biological_process	cytoplasmic translational initiation
I6	0003743	molecular_function	translation initiation factor activity
I6	0005515	molecular_function	protein binding
I6	0005737	cellular_component	cytoplasm
I6	0005829	cellular_component	cytosol
I6	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
I6	0006412	biological_process	translation
I6	0006413	biological_process	translational initiation
I6	0016282	cellular_component	eukaryotic 43S preinitiation complex
I6	0031369	molecular_function	translation initiation factor binding
I6	0032991	cellular_component	protein-containing complex
I6	0033290	cellular_component	eukaryotic 48S preinitiation complex
I6	0071541	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3m
I8	0001732	biological_process	formation of cytoplasmic translation initiation complex
I8	0002183	biological_process	cytoplasmic translational initiation
I8	0003723	molecular_function	RNA binding
I8	0003743	molecular_function	translation initiation factor activity
I8	0005515	molecular_function	protein binding
I8	0005737	cellular_component	cytoplasm
I8	0005829	cellular_component	cytosol
I8	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
I8	0006412	biological_process	translation
I8	0006413	biological_process	translational initiation
I8	0006446	biological_process	regulation of translational initiation
I8	0008233	molecular_function	peptidase activity
I8	0008237	molecular_function	metallopeptidase activity
I8	0016020	cellular_component	membrane
I8	0016282	cellular_component	eukaryotic 43S preinitiation complex
I8	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
I8	0033290	cellular_component	eukaryotic 48S preinitiation complex
I8	0070062	cellular_component	extracellular exosome
I8	0071541	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3m
I8	0140492	molecular_function	metal-dependent deubiquitinase activity
Io	0001732	biological_process	formation of cytoplasmic translation initiation complex
Io	0002183	biological_process	cytoplasmic translational initiation
Io	0003676	molecular_function	nucleic acid binding
Io	0003723	molecular_function	RNA binding
Io	0003743	molecular_function	translation initiation factor activity
Io	0005515	molecular_function	protein binding
Io	0005634	cellular_component	nucleus
Io	0005737	cellular_component	cytoplasm
Io	0005829	cellular_component	cytosol
Io	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
Io	0006412	biological_process	translation
Io	0006413	biological_process	translational initiation
Io	0016282	cellular_component	eukaryotic 43S preinitiation complex
Io	0033290	cellular_component	eukaryotic 48S preinitiation complex
Io	0048471	cellular_component	perinuclear region of cytoplasm
Io	0075525	biological_process	viral translational termination-reinitiation
Ip	0003723	molecular_function	RNA binding
Ip	0003743	molecular_function	translation initiation factor activity
Ip	0005515	molecular_function	protein binding
Ip	0005634	cellular_component	nucleus
Ip	0005737	cellular_component	cytoplasm
Ip	0006412	biological_process	translation
Ip	0006413	biological_process	translational initiation
Ip	0006446	biological_process	regulation of translational initiation
Ip	0008135	molecular_function	translation factor activity, RNA binding
Ip	0010468	biological_process	regulation of gene expression
Ip	0016282	cellular_component	eukaryotic 43S preinitiation complex
Ip	0033290	cellular_component	eukaryotic 48S preinitiation complex
Ip	0043024	molecular_function	ribosomal small subunit binding
Ip	0043614	cellular_component	multi-eIF complex
Ip	0080090	biological_process	regulation of primary metabolic process
Iq	0000049	molecular_function	tRNA binding
Iq	0003723	molecular_function	RNA binding
Iq	0003743	molecular_function	translation initiation factor activity
Iq	0005515	molecular_function	protein binding
Iq	0005737	cellular_component	cytoplasm
Iq	0005829	cellular_component	cytosol
Iq	0006412	biological_process	translation
Iq	0006413	biological_process	translational initiation
Iq	0008135	molecular_function	translation factor activity, RNA binding
Iq	0016282	cellular_component	eukaryotic 43S preinitiation complex
Iq	0033290	cellular_component	eukaryotic 48S preinitiation complex
Iq	0042255	biological_process	ribosome assembly
Iq	0043614	cellular_component	multi-eIF complex
Iq	0045202	cellular_component	synapse
Ir	0000423	biological_process	mitophagy
Ir	0003676	molecular_function	nucleic acid binding
Ir	0003723	molecular_function	RNA binding
Ir	0003743	molecular_function	translation initiation factor activity
Ir	0005515	molecular_function	protein binding
Ir	0005634	cellular_component	nucleus
Ir	0005737	cellular_component	cytoplasm
Ir	0005739	cellular_component	mitochondrion
Ir	0005829	cellular_component	cytosol
Ir	0005850	cellular_component	eukaryotic translation initiation factor 2 complex
Ir	0006412	biological_process	translation
Ir	0006413	biological_process	translational initiation
Ir	0006417	biological_process	regulation of translation
Ir	0006446	biological_process	regulation of translational initiation
Ir	0010494	cellular_component	cytoplasmic stress granule
Ir	0016020	cellular_component	membrane
Ir	0032057	biological_process	negative regulation of translational initiation in response to stress
Ir	0033290	cellular_component	eukaryotic 48S preinitiation complex
Ir	0034063	biological_process	stress granule assembly
Ir	0034198	biological_process	cellular response to amino acid starvation
Ir	0034599	biological_process	cellular response to oxidative stress
Ir	0034605	biological_process	cellular response to heat
Ir	0034644	biological_process	cellular response to UV
Ir	0034976	biological_process	response to endoplasmic reticulum stress
Ir	0036490	biological_process	regulation of translation in response to endoplasmic reticulum stress
Ir	0036499	biological_process	PERK-mediated unfolded protein response
Ir	0043022	molecular_function	ribosome binding
Ir	0044207	cellular_component	translation initiation ternary complex
Ir	0045202	cellular_component	synapse
Ir	0070062	cellular_component	extracellular exosome
Ir	0097451	cellular_component	glial limiting end-foot
Ir	0140468	biological_process	HRI-mediated signaling
Ir	0160296	molecular_function	cap-dependent translation initiation factor activity
Ir	0160297	molecular_function	IRES-mediated translation initiation factor activity
Ir	1904373	biological_process	response to kainic acid
Ir	1990737	biological_process	response to manganese-induced endoplasmic reticulum stress
Ir	2000676	biological_process	positive regulation of type B pancreatic cell apoptotic process
Is	0001731	biological_process	formation of translation preinitiation complex
Is	0002183	biological_process	cytoplasmic translational initiation
Is	0003723	molecular_function	RNA binding
Is	0003729	molecular_function	mRNA binding
Is	0003743	molecular_function	translation initiation factor activity
Is	0005515	molecular_function	protein binding
Is	0005634	cellular_component	nucleus
Is	0005737	cellular_component	cytoplasm
Is	0005829	cellular_component	cytosol
Is	0005850	cellular_component	eukaryotic translation initiation factor 2 complex
Is	0006412	biological_process	translation
Is	0006413	biological_process	translational initiation
Is	0006446	biological_process	regulation of translational initiation
Is	0008135	molecular_function	translation factor activity, RNA binding
Is	0008270	molecular_function	zinc ion binding
Is	0031369	molecular_function	translation initiation factor binding
Is	0045202	cellular_component	synapse
Is	0046872	molecular_function	metal ion binding
It	0000049	molecular_function	tRNA binding
It	0000166	molecular_function	nucleotide binding
It	0001731	biological_process	formation of translation preinitiation complex
It	0002183	biological_process	cytoplasmic translational initiation
It	0003743	molecular_function	translation initiation factor activity
It	0003924	molecular_function	GTPase activity
It	0005515	molecular_function	protein binding
It	0005525	molecular_function	GTP binding
It	0005634	cellular_component	nucleus
It	0005737	cellular_component	cytoplasm
It	0005829	cellular_component	cytosol
It	0005850	cellular_component	eukaryotic translation initiation factor 2 complex
It	0006412	biological_process	translation
It	0006413	biological_process	translational initiation
It	0006446	biological_process	regulation of translational initiation
It	0008135	molecular_function	translation factor activity, RNA binding
It	0016787	molecular_function	hydrolase activity
It	0045296	molecular_function	cadherin binding
It	0070062	cellular_component	extracellular exosome
It	1990856	molecular_function	methionyl-initiator methionine tRNA binding
Iu	0001732	biological_process	formation of cytoplasmic translation initiation complex
Iu	0002183	biological_process	cytoplasmic translational initiation
Iu	0002188	biological_process	translation reinitiation
Iu	0003723	molecular_function	RNA binding
Iu	0003729	molecular_function	mRNA binding
Iu	0003743	molecular_function	translation initiation factor activity
Iu	0005198	molecular_function	structural molecule activity
Iu	0005515	molecular_function	protein binding
Iu	0005737	cellular_component	cytoplasm
Iu	0005829	cellular_component	cytosol
Iu	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
Iu	0005874	cellular_component	microtubule
Iu	0006412	biological_process	translation
Iu	0006413	biological_process	translational initiation
Iu	0014069	cellular_component	postsynaptic density
Iu	0016020	cellular_component	membrane
Iu	0016282	cellular_component	eukaryotic 43S preinitiation complex
Iu	0030971	molecular_function	receptor tyrosine kinase binding
Iu	0032991	cellular_component	protein-containing complex
Iu	0033290	cellular_component	eukaryotic 48S preinitiation complex
Iu	0043226	cellular_component	organelle
Iu	0043614	cellular_component	multi-eIF complex
Iu	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
Iu	0071540	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3e
Iu	0071541	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3m
Iu	0075522	biological_process	IRES-dependent viral translational initiation
Iu	0075525	biological_process	viral translational termination-reinitiation
Iv	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Iv	0000785	cellular_component	chromatin
Iv	0001732	biological_process	formation of cytoplasmic translation initiation complex
Iv	0002183	biological_process	cytoplasmic translational initiation
Iv	0003723	molecular_function	RNA binding
Iv	0003743	molecular_function	translation initiation factor activity
Iv	0005515	molecular_function	protein binding
Iv	0005634	cellular_component	nucleus
Iv	0005654	cellular_component	nucleoplasm
Iv	0005737	cellular_component	cytoplasm
Iv	0005829	cellular_component	cytosol
Iv	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
Iv	0006412	biological_process	translation
Iv	0006413	biological_process	translational initiation
Iv	0006446	biological_process	regulation of translational initiation
Iv	0014069	cellular_component	postsynaptic density
Iv	0016020	cellular_component	membrane
Iv	0016282	cellular_component	eukaryotic 43S preinitiation complex
Iv	0016605	cellular_component	PML body
Iv	0032991	cellular_component	protein-containing complex
Iv	0033290	cellular_component	eukaryotic 48S preinitiation complex
Iv	0045296	molecular_function	cadherin binding
Iv	0045727	biological_process	positive regulation of translation
Iv	0045947	biological_process	negative regulation of translational initiation
Iv	0070062	cellular_component	extracellular exosome
Iv	0071540	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3e
Ix	0001732	biological_process	formation of cytoplasmic translation initiation complex
Ix	0002183	biological_process	cytoplasmic translational initiation
Ix	0002191	biological_process	cap-dependent translational initiation
Ix	0003723	molecular_function	RNA binding
Ix	0003743	molecular_function	translation initiation factor activity
Ix	0005515	molecular_function	protein binding
Ix	0005737	cellular_component	cytoplasm
Ix	0005829	cellular_component	cytosol
Ix	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
Ix	0006412	biological_process	translation
Ix	0006413	biological_process	translational initiation
Ix	0016020	cellular_component	membrane
Ix	0016282	cellular_component	eukaryotic 43S preinitiation complex
Ix	0033290	cellular_component	eukaryotic 48S preinitiation complex
Ix	0045202	cellular_component	synapse
Ix	0071541	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3m
Ix	0075522	biological_process	IRES-dependent viral translational initiation
Ix	0075525	biological_process	viral translational termination-reinitiation
Ix	0098808	molecular_function	mRNA cap binding
Iy	0001732	biological_process	formation of cytoplasmic translation initiation complex
Iy	0002183	biological_process	cytoplasmic translational initiation
Iy	0003723	molecular_function	RNA binding
Iy	0003743	molecular_function	translation initiation factor activity
Iy	0005515	molecular_function	protein binding
Iy	0005737	cellular_component	cytoplasm
Iy	0005829	cellular_component	cytosol
Iy	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
Iy	0006412	biological_process	translation
Iy	0006413	biological_process	translational initiation
Iy	0016282	cellular_component	eukaryotic 43S preinitiation complex
Iy	0031369	molecular_function	translation initiation factor binding
Iy	0033290	cellular_component	eukaryotic 48S preinitiation complex
Iy	0043022	molecular_function	ribosome binding
Iy	0045727	biological_process	positive regulation of translation

Functional Information from PROSITE/UniProt

site_id	PS00733
Number of Residues	8
Details	RIBOSOMAL_S26E Ribosomal protein S26e signature. YCVSCAIH

Chain	Residue	Details
Aa	TYR73-HIS80

---

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PshfsrgSksVaRrVLQaLE

Chain	Residue	Details
AT	PRO89-GLU108

---

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
AX	LYS60-ARG67

---

site_id	PS01262
Number of Residues	23
Details	IF1A Eukaryotic initiation factor 1A signature. MlGnGRleamCfDGvkRlcHIrG

Chain	Residue	Details
Iq	MET41-GLY63

---

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY

Chain	Residue	Details
AN	VAL98-TYR128

---

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsMMmhgrnnGKKlmtvrIVkhA

Chain	Residue	Details
AF	GLU70-ALA96

---

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RrkTGGkrkpy.HkKrKyELG

Chain	Residue	Details
AI	ARG11-GLY30

---

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM

Chain	Residue	Details
AG	ILE52-MET63

---

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRVAaPkhWmLdK

Chain	Residue	Details
AE	HIS8-LYS22

---

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAfvAIGDyn.GhVGlGvkcsk.EVat.AI

Chain	Residue	Details
AC	GLY119-ILE151

---

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkekNLkvkGPVrMPT

Chain	Residue	Details
AU	ALA43-THR58

---

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GMkIgrieDvTPiPSD

Chain	Residue	Details
AO	LEU116-IAS138

---

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsnrhglirkyg.LNMCRqCFR

Chain	Residue	Details
Ad	ARG22-ARG44

---

site_id	PS00996
Number of Residues	9
Details	RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA

Chain	Residue	Details
AV	LEU11-ALA19

---

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgEcRPLS

Chain	Residue	Details
AL	GLY123-SER135

---

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVFKlglAkSihhARvLI

Chain	Residue	Details
AJ	LEU106-ILE130

---

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVfEvSLaDL

Chain	Residue	Details
AB	LEU62-LEU74

---

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgCykittvFShAqtvvlCvgCStvLcqPtG

Chain	Residue	Details
Ab	LYS36-GLY68

---

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GfiVLTTSaGIMdheeAR

Chain	Residue	Details
AW	GLY100-ARG117

---

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKtfnqveIkpemIGhyLGEFsiT

Chain	Residue	Details
AP	ASN98-THR122

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSGswDgTLRLWDL

Chain	Residue	Details
Ag	ALA78-LEU92
Ag	ILE120-THR134
Ag	ILE165-LEU179
Ag	CYS207-LEU221

---

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
Ac	GLU60-LEU68

---

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKTtGFGmIYDSldyakknE

Chain	Residue	Details
AY	PHE64-GLU86

---

site_id	PS00948
Number of Residues	14
Details	RIBOSOMAL_S7E Ribosomal protein S7e signature. RLvRELEKKFSgKH

Chain	Residue	Details
AH	ARG78-HIS91

---

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfvdGlMihSgdpVnyyVDtavrhvlLrqGvlG

Chain	Residue	Details
AD	ALA147-GLY183

---

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VlKFLAAGTHLG

Chain	Residue	Details
AA	VAL15-GLY26

---

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlLVVtDpraDhqpLtEasyvNLP

Chain	Residue	Details
AA	PRO119-PRO143

---

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvAQiyAirqSiSKAL

Chain	Residue	Details
AQ	GLY74-LEU92

---

site_id	PS01189
Number of Residues	19
Details	RIBOSOMAL_S12E Ribosomal protein S12e signature. ALQevLktAlihDGLarGI

Chain	Residue	Details
AM	ALA17-ILE35

---

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IpSKkLRNkIAGYvTH

Chain	Residue	Details
AR	ILE41-HIS56

---

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHfwGlrVRGQ

Chain	Residue	Details
AS	ARG121-GLN134

---

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KahVaSlegIApedQvVLLaGapleD

Chain	Residue	Details
Ae	LYS-49-ASP-24
Af	LYS27-ASP52

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1063
Details	Domain: {"description":"PCI","evidences":[{"source":"PROSITE-ProRule","id":"PRU01185","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"HAMAP-Rule","id":"MF_03010","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17322308","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"DEC-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Zebisch A.","Kolch W."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	11
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	264
Details	Domain: {"description":"MPN","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	24
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"HAMAP-Rule","id":"MF_03005","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17322308","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	21
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	115
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	19
Details	Compositional bias: {"description":"Low complexity","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"HAMAP-Rule","id":"MF_03007","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17322308","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	24
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	2
Details	Site: {"description":"Binds 40S ribosomal subunit","evidences":[{"source":"PubMed","id":"29987188","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	74
Details	Domain: {"description":"S1-like"}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	71
Details	Domain: {"description":"S1 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00180","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by HRI","evidences":[{"source":"UniProtKB","id":"P83268","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"38340717","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	46
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P41035","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	209
Details	Domain: {"description":"tr-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	7
Details	Region: {"description":"G1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	4
Details	Region: {"description":"G2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	3
Details	Region: {"description":"G3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	3
Details	Region: {"description":"G4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	2
Details	Region: {"description":"G5","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	12
Details	Region: {"description":"Interacts with CDC123","evidences":[{"source":"PubMed","id":"35031321","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P32481","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9Z0N1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	38
Details	Coiled coil: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03000","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	124
Details	Region: {"description":"Sufficient for interaction with EPAS1","evidences":[{"source":"PubMed","id":"17324924","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	186
Details	Region: {"description":"Sufficient for interaction with TRIM27","evidences":[{"source":"PubMed","id":"10504338","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"HAMAP-Rule","id":"MF_03004","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17322308","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAR-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Heiserich L.","Gottlieb E.","Matallanas D.","Cooper W.N.","Kolch W."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	14
Details	Region: {"description":"RNA gate","evidences":[{"source":"UniProtKB","id":"K7IM66","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"O70194","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	39
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	9
Details	Compositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"HAMAP-Rule","id":"MF_03002","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17322308","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q8R1B4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	59
Details	Region: {"description":"Interaction with PPP1R16B","evidences":[{"source":"PubMed","id":"16263087","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	19
Details	Region: {"description":"Laminin-binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	1
Details	Site: {"description":"Cleavage; by ST3; site 1","evidences":[{"source":"HAMAP-Rule","id":"MF_03016","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	1
Details	Site: {"description":"Cleavage; by ST3; site 2","evidences":[{"source":"HAMAP-Rule","id":"MF_03016","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P14206","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	11
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	6
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P97351","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	1
Details	Modified residue: {"description":"ADP-ribosyltyrosine","evidences":[{"source":"PubMed","id":"29954836","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI52
Number of Residues	63
Details	Domain: {"description":"S5 DRBM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00268","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI53
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"28132843","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI54
Number of Residues	71
Details	Domain: {"description":"KH type-2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00118","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI55
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by PKC/PRKCD","evidences":[{"source":"PubMed","id":"19059439","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI56
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by MAPK","evidences":[{"source":"PubMed","id":"15950189","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI57
Number of Residues	3
Details	Modified residue: {"description":"Asymmetric dimethylarginine; by PRMT1","evidences":[{"source":"PubMed","id":"19460357","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI58
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by PKB","evidences":[{"source":"PubMed","id":"20605787","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI59
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62908","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI60
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by IKKB","evidences":[{"source":"PubMed","id":"21399639","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI61
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by CDK1 and PKC/PRKCD","evidences":[{"source":"PubMed","id":"19059439","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21871177","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAR-2009","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Waridel P.","Quadroni M."]}},{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI62
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16807684","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI63
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)"}

Chain

Residue

Details

---

site_id	SWS_FT_FI64
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"28065601","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28132843","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31981475","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32011234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34348161","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34469731","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI65
Number of Residues	62
Details	Domain: {"description":"S4 RNA-binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI66
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P62702","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI67
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI68
Number of Residues	1
Details	Modified residue: {"description":"ADP-ribosyl glutamic acid","evidences":[{"source":"PubMed","id":"34314702","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI69
Number of Residues	1
Details	Modified residue: {"description":"(3R)-3-hydroxyarginine","evidences":[{"source":"PubMed","id":"29563586","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI70
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by RPS6KA1, RPS6KA3, DAPK1 and PASK","evidences":[{"source":"PubMed","id":"17360704","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18974095","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21418524","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI71
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by RPS6KA1, RPS6KA3, DAPK1 and PASK","evidences":[{"source":"PubMed","id":"17360704","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18974095","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21418524","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI72
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI73
Number of Residues	49
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI74
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P62242","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI75
Number of Residues	1
Details	Lipidation: {"description":"N-myristoyl glycine","evidences":[{"source":"PubMed","id":"25255805","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI76
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q6ZWN5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI77
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P63325","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI78
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2006","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Kanor S.","Tissot J.-D.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI79
Number of Residues	1
Details	Modified residue: {"description":"Citrulline","evidences":[{"source":"UniProtKB","id":"P62281","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI80
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P62281","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI81
Number of Residues	1
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"UniProtKB","id":"P62281","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI82
Number of Residues	1
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"PubMed","id":"21044946","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI83
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P63323","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI84
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62301","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI85
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62301","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI86
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI87
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"36638793","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI88
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI89
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P63276","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI90
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI91
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI92
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"36638793","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI93
Number of Residues	2
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI94
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9CZX8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI95
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P60867","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI96
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI97
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62245","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI99
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI100
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P62852","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI101
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62852","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI102
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34516797","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7MQ8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI103
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI104
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25957688","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5A2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJ0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI105
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25957688","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5A2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FLX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LKS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI106
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25957688","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5A2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LKS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI107
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62862","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI108
Number of Residues	23
Details	Zinc finger: {"description":"C4-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI109
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"32129764","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36638793","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI110
Number of Residues	31
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI111
Number of Residues	30
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI112
Number of Residues	30
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI113
Number of Residues	32
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI114
Number of Residues	30
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI115
Number of Residues	29
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI116
Number of Residues	30
Details	Repeat: {"description":"WD 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI117
Number of Residues	1
Details	Modified residue: {"description":"N-acetylthreonine; in Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2006","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Kanor S.","Tissot J.-D.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI118
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine; by ABL1","evidences":[{"source":"PubMed","id":"19423701","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI119
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P68040","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI120
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"11279199","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI121
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by viral VacV B1 kinase","evidences":[{"source":"PubMed","id":"28636603","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI122
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by viral VacV B1 kinase","evidences":[{"source":"PubMed","id":"28636603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI123
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by viral VacV B1 kinase","evidences":[{"source":"PubMed","id":"28636603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI124
Number of Residues	28
Details	Domain: {"description":"BetaCoV Nsp1 C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU01308","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---