8PPA
Human inositol 1,4,5-trisphosphate 3-kinase A (IP3K) catalytic domain in complex with D-myo-inositol 1,4,6-trisphosphate/AMP-PNP/Mn
Functional Information from GO Data
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:15350214, ECO:0007744|PDB:1W2D |
Chain | Residue | Details |
A | SER197 | |
B | SER197 |
site_id | SWS_FT_FI2 |
Number of Residues | 16 |
Details | BINDING: BINDING => ECO:0000269|PubMed:15350214, ECO:0007744|PDB:1W2C |
Chain | Residue | Details |
A | LYS209 | |
B | GLN249 | |
B | ASP262 | |
B | LYS264 | |
B | ARG285 | |
B | LYS336 | |
B | ASP416 | |
B | LYS419 | |
A | GLN249 | |
A | ASP262 | |
A | LYS264 | |
A | ARG285 | |
A | LYS336 | |
A | ASP416 | |
A | LYS419 | |
B | LYS209 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:15350214 |
Chain | Residue | Details |
A | LYS312 | |
B | LYS312 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
A | SER197 | |
B | SER197 |