8P53

Cryo-EM structure of the c-di-GMP-free FleQ-FleN master regulator complex of P. aeruginosa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0009898	cellular_component	cytoplasmic side of plasma membrane
A	0016887	molecular_function	ATP hydrolysis activity
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0009898	cellular_component	cytoplasmic side of plasma membrane
B	0016887	molecular_function	ATP hydrolysis activity
C	0000166	molecular_function	nucleotide binding
C	0000976	molecular_function	transcription cis-regulatory region binding
C	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
C	0001216	molecular_function	DNA-binding transcription activator activity
C	0001217	molecular_function	DNA-binding transcription repressor activity
C	0003677	molecular_function	DNA binding
C	0005524	molecular_function	ATP binding
C	0006351	biological_process	DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription
C	0008134	molecular_function	transcription factor binding
C	0010811	biological_process	positive regulation of cell-substrate adhesion
C	0032993	cellular_component	protein-DNA complex
C	0035438	molecular_function	cyclic-di-GMP binding
C	0043565	molecular_function	sequence-specific DNA binding
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	1901202	biological_process	negative regulation of extracellular matrix assembly
C	1902021	biological_process	regulation of bacterial-type flagellum-dependent cell motility
C	2000155	biological_process	positive regulation of cilium-dependent cell motility
D	0000166	molecular_function	nucleotide binding
D	0000976	molecular_function	transcription cis-regulatory region binding
D	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
D	0001216	molecular_function	DNA-binding transcription activator activity
D	0001217	molecular_function	DNA-binding transcription repressor activity
D	0003677	molecular_function	DNA binding
D	0005524	molecular_function	ATP binding
D	0006351	biological_process	DNA-templated transcription
D	0006355	biological_process	regulation of DNA-templated transcription
D	0008134	molecular_function	transcription factor binding
D	0010811	biological_process	positive regulation of cell-substrate adhesion
D	0032993	cellular_component	protein-DNA complex
D	0035438	molecular_function	cyclic-di-GMP binding
D	0043565	molecular_function	sequence-specific DNA binding
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0045893	biological_process	positive regulation of DNA-templated transcription
D	1901202	biological_process	negative regulation of extracellular matrix assembly
D	1902021	biological_process	regulation of bacterial-type flagellum-dependent cell motility
D	2000155	biological_process	positive regulation of cilium-dependent cell motility
E	0000166	molecular_function	nucleotide binding
E	0000976	molecular_function	transcription cis-regulatory region binding
E	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
E	0001216	molecular_function	DNA-binding transcription activator activity
E	0001217	molecular_function	DNA-binding transcription repressor activity
E	0003677	molecular_function	DNA binding
E	0005524	molecular_function	ATP binding
E	0006351	biological_process	DNA-templated transcription
E	0006355	biological_process	regulation of DNA-templated transcription
E	0008134	molecular_function	transcription factor binding
E	0010811	biological_process	positive regulation of cell-substrate adhesion
E	0032993	cellular_component	protein-DNA complex
E	0035438	molecular_function	cyclic-di-GMP binding
E	0043565	molecular_function	sequence-specific DNA binding
E	0045892	biological_process	negative regulation of DNA-templated transcription
E	0045893	biological_process	positive regulation of DNA-templated transcription
E	1901202	biological_process	negative regulation of extracellular matrix assembly
E	1902021	biological_process	regulation of bacterial-type flagellum-dependent cell motility
E	2000155	biological_process	positive regulation of cilium-dependent cell motility
F	0000166	molecular_function	nucleotide binding
F	0000976	molecular_function	transcription cis-regulatory region binding
F	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
F	0001216	molecular_function	DNA-binding transcription activator activity
F	0001217	molecular_function	DNA-binding transcription repressor activity
F	0003677	molecular_function	DNA binding
F	0005524	molecular_function	ATP binding
F	0006351	biological_process	DNA-templated transcription
F	0006355	biological_process	regulation of DNA-templated transcription
F	0008134	molecular_function	transcription factor binding
F	0010811	biological_process	positive regulation of cell-substrate adhesion
F	0032993	cellular_component	protein-DNA complex
F	0035438	molecular_function	cyclic-di-GMP binding
F	0043565	molecular_function	sequence-specific DNA binding
F	0045892	biological_process	negative regulation of DNA-templated transcription
F	0045893	biological_process	positive regulation of DNA-templated transcription
F	1901202	biological_process	negative regulation of extracellular matrix assembly
F	1902021	biological_process	regulation of bacterial-type flagellum-dependent cell motility
F	2000155	biological_process	positive regulation of cilium-dependent cell motility

Functional Information from PROSITE/UniProt

site_id	PS00675
Number of Residues	14
Details	SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. VLIlGESGTGKevV

Chain	Residue	Details
C	VAL170-VAL183

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site_id	PS00676
Number of Residues	16
Details	SIGMA54_INTERACT_2 Sigma-54 interaction domain ATP-binding region B signature. GrFelANGGTLFLDEI

Chain	Residue	Details
C	GLY232-ILE247

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site_id	PS00688
Number of Residues	10
Details	SIGMA54_INTERACT_3 Sigma-54 interaction domain C-terminal part signature. WPGNVRELaN

Chain	Residue	Details
C	TRP358-ASN367

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28065505","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5J1J","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26712005","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5EXX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26712005","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5EXT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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