8P2M

C. elegans TIR-1 protein.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003953	molecular_function	NAD+ nucleosidase activity
A	0007165	biological_process	signal transduction
A	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
A	0035591	molecular_function	signaling adaptor activity
A	0048678	biological_process	response to axon injury
B	0003953	molecular_function	NAD+ nucleosidase activity
B	0007165	biological_process	signal transduction
B	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
B	0035591	molecular_function	signaling adaptor activity
B	0048678	biological_process	response to axon injury
C	0003953	molecular_function	NAD+ nucleosidase activity
C	0007165	biological_process	signal transduction
C	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
C	0035591	molecular_function	signaling adaptor activity
C	0048678	biological_process	response to axon injury
D	0003953	molecular_function	NAD+ nucleosidase activity
D	0007165	biological_process	signal transduction
D	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
D	0035591	molecular_function	signaling adaptor activity
D	0048678	biological_process	response to axon injury
E	0003953	molecular_function	NAD+ nucleosidase activity
E	0007165	biological_process	signal transduction
E	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
E	0035591	molecular_function	signaling adaptor activity
E	0048678	biological_process	response to axon injury
F	0003953	molecular_function	NAD+ nucleosidase activity
F	0007165	biological_process	signal transduction
F	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
F	0035591	molecular_function	signaling adaptor activity
F	0048678	biological_process	response to axon injury
G	0003953	molecular_function	NAD+ nucleosidase activity
G	0007165	biological_process	signal transduction
G	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
G	0035591	molecular_function	signaling adaptor activity
G	0048678	biological_process	response to axon injury
H	0003953	molecular_function	NAD+ nucleosidase activity
H	0007165	biological_process	signal transduction
H	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
H	0035591	molecular_function	signaling adaptor activity
H	0048678	biological_process	response to axon injury
I	0003953	molecular_function	NAD+ nucleosidase activity
I	0007165	biological_process	signal transduction
I	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
I	0035591	molecular_function	signaling adaptor activity
I	0048678	biological_process	response to axon injury

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	576
Details	Domain: {"description":"SAM 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00184","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	66
Details	Domain: {"description":"SAM 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00184","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	97
Details	Domain: {"description":"TIR","evidences":[{"source":"PROSITE-ProRule","id":"PRU00204","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	9
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00204","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00204","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---