8OXZ

Rat alpha5beta1 integrin, headpiece

Functional Information from GO Data

Chain	GOid	namespace	contents
P	0007155	biological_process	cell adhesion
P	0008305	cellular_component	integrin complex

Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CrCneGrvGRhC

Chain	Residue	Details
Q	CYS490-CYS501
Q	CYS580-CYS591

---

site_id	PS00070
Number of Residues	12
Details	ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. VaTNGQICNGRG

Chain	Residue	Details
Q	VAL601-GLY612

---

site_id	PS00242
Number of Residues	8
Details	INTEGRIN_ALPHA Integrins alpha chain signature. YKlGFFkR

Chain	Residue	Details
P	TYR1071-ARG1078

---

site_id	PS00243
Number of Residues	14
Details	I_EGF_1 Integrins beta chain EGF (I-EGF) domain signature. CsNn..GeCvCgqCvC

Chain	Residue	Details
Q	CYS526-CYS539
Q	CYS569-CYS582
Q	CYS608-CYS621

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI3
Number of Residues	50
Details	Domain: {"description":"PSI","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	238
Details	Domain: {"description":"VWFA","evidences":[{"source":"UniProtKB","id":"P05106","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	35
Details	Domain: {"description":"I-EGF 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01392","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	25
Details	Region: {"description":"CX3CL1-binding","evidences":[{"source":"UniProtKB","id":"P05556","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	83
Details	Region: {"description":"Interaction with TMEM182","evidences":[{"source":"UniProtKB","id":"P07228","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	3
Details	Binding site: {"description":"in MIDAS binding site","evidences":[{"source":"UniProtKB","id":"P05556","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	3
Details	Binding site: {"description":"in ADMIDAS binding site","evidences":[{"source":"UniProtKB","id":"P05556","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	4
Details	Binding site: {"description":"in LIMBS binding site","evidences":[{"source":"UniProtKB","id":"P05556","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	9
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---