Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8OVJ

CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : PARENTAL STRAIN

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003735	molecular_function	structural constituent of ribosome
A	0005840	cellular_component	ribosome
A	0006412	biological_process	translation
B	0003735	molecular_function	structural constituent of ribosome
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
C	0003735	molecular_function	structural constituent of ribosome
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
D	0003735	molecular_function	structural constituent of ribosome
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0019843	molecular_function	rRNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
G	0003723	molecular_function	RNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0015934	cellular_component	large ribosomal subunit
I	0003735	molecular_function	structural constituent of ribosome
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
J	0003735	molecular_function	structural constituent of ribosome
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
L	0003735	molecular_function	structural constituent of ribosome
L	0006412	biological_process	translation
L	0015934	cellular_component	large ribosomal subunit
M	0003735	molecular_function	structural constituent of ribosome
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
N	0003735	molecular_function	structural constituent of ribosome
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
O	0003735	molecular_function	structural constituent of ribosome
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0008097	molecular_function	5S rRNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0022625	cellular_component	cytosolic large ribosomal subunit
R	0003735	molecular_function	structural constituent of ribosome
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
S	0003735	molecular_function	structural constituent of ribosome
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
SA	0003735	molecular_function	structural constituent of ribosome
SA	0005840	cellular_component	ribosome
SA	0006412	biological_process	translation
SB	0003735	molecular_function	structural constituent of ribosome
SB	0005840	cellular_component	ribosome
SB	0006412	biological_process	translation
SB	0015935	cellular_component	small ribosomal subunit
SC	0003723	molecular_function	RNA binding
SC	0003735	molecular_function	structural constituent of ribosome
SC	0006412	biological_process	translation
SC	0015935	cellular_component	small ribosomal subunit
SD	0003723	molecular_function	RNA binding
SD	0003735	molecular_function	structural constituent of ribosome
SD	0006412	biological_process	translation
SD	0015935	cellular_component	small ribosomal subunit
SD	0019843	molecular_function	rRNA binding
SE	0003723	molecular_function	RNA binding
SE	0003735	molecular_function	structural constituent of ribosome
SE	0005840	cellular_component	ribosome
SE	0006412	biological_process	translation
SF	0003723	molecular_function	RNA binding
SF	0003735	molecular_function	structural constituent of ribosome
SF	0005840	cellular_component	ribosome
SF	0006412	biological_process	translation
SF	0015935	cellular_component	small ribosomal subunit
SG	0003735	molecular_function	structural constituent of ribosome
SG	0005840	cellular_component	ribosome
SG	0006412	biological_process	translation
SH	0003735	molecular_function	structural constituent of ribosome
SH	0006412	biological_process	translation
SH	0015935	cellular_component	small ribosomal subunit
SI	0003735	molecular_function	structural constituent of ribosome
SI	0005840	cellular_component	ribosome
SI	0006412	biological_process	translation
SJ	0003735	molecular_function	structural constituent of ribosome
SJ	0005840	cellular_component	ribosome
SJ	0006412	biological_process	translation
SK	0003735	molecular_function	structural constituent of ribosome
SK	0005840	cellular_component	ribosome
SK	0006412	biological_process	translation
SL	0003735	molecular_function	structural constituent of ribosome
SL	0005840	cellular_component	ribosome
SL	0006412	biological_process	translation
SM	0003735	molecular_function	structural constituent of ribosome
SM	0005840	cellular_component	ribosome
SM	0006412	biological_process	translation
SM	0015935	cellular_component	small ribosomal subunit
SO	0003735	molecular_function	structural constituent of ribosome
SO	0005840	cellular_component	ribosome
SO	0006412	biological_process	translation
SP	0003735	molecular_function	structural constituent of ribosome
SP	0005840	cellular_component	ribosome
SP	0006412	biological_process	translation
SP	0015935	cellular_component	small ribosomal subunit
SQ	0003735	molecular_function	structural constituent of ribosome
SQ	0005840	cellular_component	ribosome
SQ	0006412	biological_process	translation
SR	0003676	molecular_function	nucleic acid binding
SR	0003723	molecular_function	RNA binding
SR	0003735	molecular_function	structural constituent of ribosome
SR	0005840	cellular_component	ribosome
SR	0006412	biological_process	translation
SS	0003735	molecular_function	structural constituent of ribosome
SS	0005840	cellular_component	ribosome
SS	0006412	biological_process	translation
SS	0008270	molecular_function	zinc ion binding
ST	0003735	molecular_function	structural constituent of ribosome
ST	0005840	cellular_component	ribosome
ST	0006412	biological_process	translation
SU	0003735	molecular_function	structural constituent of ribosome
SU	0005840	cellular_component	ribosome
SU	0006412	biological_process	translation
SV	0003735	molecular_function	structural constituent of ribosome
SV	0005840	cellular_component	ribosome
SV	0006412	biological_process	translation
SW	0003723	molecular_function	RNA binding
SW	0003735	molecular_function	structural constituent of ribosome
SW	0005840	cellular_component	ribosome
SW	0006412	biological_process	translation
SW	0015935	cellular_component	small ribosomal subunit
SX	0003735	molecular_function	structural constituent of ribosome
SX	0005840	cellular_component	ribosome
SX	0006412	biological_process	translation
SY	0003735	molecular_function	structural constituent of ribosome
SY	0005840	cellular_component	ribosome
SY	0006412	biological_process	translation
SZ	0003735	molecular_function	structural constituent of ribosome
SZ	0005840	cellular_component	ribosome
SZ	0006412	biological_process	translation
Sb	0003735	molecular_function	structural constituent of ribosome
Sb	0005840	cellular_component	ribosome
Sb	0006412	biological_process	translation
Sc	0003735	molecular_function	structural constituent of ribosome
Sc	0005840	cellular_component	ribosome
Sc	0006412	biological_process	translation
Sd	0003735	molecular_function	structural constituent of ribosome
Sd	0005840	cellular_component	ribosome
Sd	0006412	biological_process	translation
Se	0003735	molecular_function	structural constituent of ribosome
Se	0005840	cellular_component	ribosome
Se	0006412	biological_process	translation
Sg	0043022	molecular_function	ribosome binding
Sg	0045182	molecular_function	translation regulator activity
Sh	0003676	molecular_function	nucleic acid binding
Sh	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0015934	cellular_component	large ribosomal subunit
U	0003735	molecular_function	structural constituent of ribosome
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
V	0003735	molecular_function	structural constituent of ribosome
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0019843	molecular_function	rRNA binding
W	0003723	molecular_function	RNA binding
W	0003735	molecular_function	structural constituent of ribosome
W	0006412	biological_process	translation
W	0015934	cellular_component	large ribosomal subunit
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
a	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
a	0003735	molecular_function	structural constituent of ribosome
a	0005840	cellular_component	ribosome
a	0006412	biological_process	translation
a	0022625	cellular_component	cytosolic large ribosomal subunit
b	0003735	molecular_function	structural constituent of ribosome
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
c	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
c	0003723	molecular_function	RNA binding
c	0003735	molecular_function	structural constituent of ribosome
d	0003723	molecular_function	RNA binding
e	0003735	molecular_function	structural constituent of ribosome
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
f	0003735	molecular_function	structural constituent of ribosome
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
g	0003735	molecular_function	structural constituent of ribosome
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
h	0003735	molecular_function	structural constituent of ribosome
h	0005840	cellular_component	ribosome
h	0006412	biological_process	translation
i	0003735	molecular_function	structural constituent of ribosome
i	0005840	cellular_component	ribosome
i	0006412	biological_process	translation
j	0003735	molecular_function	structural constituent of ribosome
j	0005840	cellular_component	ribosome
j	0006412	biological_process	translation
k	0003735	molecular_function	structural constituent of ribosome
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
l	0003735	molecular_function	structural constituent of ribosome
l	0005840	cellular_component	ribosome
l	0006412	biological_process	translation
m	0003735	molecular_function	structural constituent of ribosome
m	0005840	cellular_component	ribosome
m	0006412	biological_process	translation
n	0003735	molecular_function	structural constituent of ribosome
n	0005840	cellular_component	ribosome
n	0006412	biological_process	translation
o	0003735	molecular_function	structural constituent of ribosome
o	0005840	cellular_component	ribosome
o	0006412	biological_process	translation
p	0003735	molecular_function	structural constituent of ribosome
p	0005840	cellular_component	ribosome
p	0006412	biological_process	translation

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVIIrqrkswrrk.DGtviyFedNagVI

Chain	Residue	Details
J	ALA78-ILE104

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYIRLSaahdaldT

Chain	Residue	Details
V	LYS123-THR138

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. RTgnrIkwNekrRHWRR

Chain	Residue	Details
l	ARG30-ARG46

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GfvVLTTSlGIMdheeAR

Chain	Residue	Details
SJ	GLY100-ARG117

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarA.GMkIgrieDvTPiPTD

Chain	Residue	Details
SO	LEU109-ASP131

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
SP	LYS60-ARG67

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDeVvIgQcRPLS

Chain	Residue	Details
SU	GLY135-SER147

site_id	PS00107
Number of Residues	22
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGMGKGARCCvIcsnqka............LIRK

Chain	Residue	Details
SS	ILE13-LYS34

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. MIYPSDVVGRRwrcrtdG

Chain	Residue	Details
SI	MET132-GLY149

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleE

Chain	Residue	Details
m	LYS27-GLU52

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGHqfnaveIkgemIGhyLGEFsmS

Chain	Residue	Details
SW	ASN105-SER129

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLCEQtpVlSrARlT

Chain	Residue	Details
D	LEU39-THR55

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGqvSQayAarqAiAKGL

Chain	Residue	Details
SL	GLY77-LEU95

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. MrkHLerhTtDrdTkyrLilVesrihrLarY

Chain	Residue	Details
ST	MET98-TYR128

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRitpymcspCHVQLfM

Chain	Residue	Details
T	ARG126-MET150

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PkvRGVArNPvE

Chain	Residue	Details
A	PRO197-GLU208

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FqqseacDvcSvTkGHGteGvvkR

Chain	Residue	Details
B	PHE214-ARG237

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKTtGFGlIYDDlaslkrfE

Chain	Residue	Details
SZ	PHE71-GLU93

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. LRGGsDkdGfPM

Chain	Residue	Details
SG	LEU53-MET64

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAfnVVGDcd.GhIGiGarvgk.EVsl.AI

Chain	Residue	Details
SF	GLY105-ILE137

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtiVFKaglAkSvhhARvLI

Chain	Residue	Details
SD	LEU104-ILE128

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. ILqlLrLrQifNtVfvkmnkpmenMLraVepYI

Chain	Residue	Details
c	ILE112-ILE144

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGvRHayGlrVRGQ

Chain	Residue	Details
SR	ARG122-GLN135

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. ALTAswDrSIRMWDL

Chain	Residue	Details
Sg	ALA80-LEU94
Sg	ILE122-VAL136
Sg	VAL167-VAL181
Sg	CYS209-LEU223

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QmclVkkKdiRkFlDGIYVqtK

Chain	Residue	Details
E	GLN162-LYS183

site_id	PS00709
Number of Residues	25
Details	RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkyvlGtQqaLTtlRqGrsKlVVI

Chain	Residue	Details
d	SER22-ILE46

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NlhqKrfAVvSALaASSvpslvmsRGH

Chain	Residue	Details
C	ASN115-HIS141

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ETEREARrL

Chain	Residue	Details
Sd	GLU77-LEU85

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrvLVVtDprtDhqaIrEaslvNIP

Chain	Residue	Details
SB	PRO122-PRO146

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. DLGTacGKhfrtcvLsVtNvG

Chain	Residue	Details
d	ASP78-GLY98

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTtSmGqRhgrt.HilCrRCG

Chain	Residue	Details
j	GLY4-GLY23

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GDyVdvvadsavre.GmpHkyYhGrTG

Chain	Residue	Details
S	GLY37-GLY62

site_id	PS01172
Number of Residues	12
Details	RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLKlqC

Chain	Residue	Details
p	LYS63-CYS74

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RkiTGGktkih.RkRmKaELG

Chain	Residue	Details
SK	ARG11-GLY30

site_id	PS01257
Number of Residues	22
Details	RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqtGMRgAFGKPnGvcARV

Chain	Residue	Details
N	ALA108-VAL129

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250

Chain	Residue	Details
m	LYS48

site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) => ECO:0000255\|PROSITE-ProRule:PRU00214

Chain	Residue	Details
m	GLY76

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)