8ORV
Crystal structure of monkeypox virus poxin in complex with the STING agonist MD1203
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004518 | molecular_function | nuclease activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_04143 |
| Chain | Residue | Details |
| A | HIS17 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Shared with catalytic histidine of dimeric partner => ECO:0000255|HAMAP-Rule:MF_04143 |
| Chain | Residue | Details |
| A | TYR138 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor; shared with catalytic histidine of dimeric partner => ECO:0000255|HAMAP-Rule:MF_04143 |
| Chain | Residue | Details |
| A | LYS142 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | SITE: Substrate binding => ECO:0000255|HAMAP-Rule:MF_04143 |
| Chain | Residue | Details |
| A | ARG60 | |
| A | ILE105 | |
| A | ASN149 | |
| A | GLN169 | |
| A | ARG182 | |
| A | ARG184 | |
| A | LYS186 |
