8OPP
Structure of human terminal uridylyltransferase 7 (hTUT7/ZCCHC6) bound with pre-let7g miRNA and UTPalphaS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001556 | biological_process | oocyte maturation |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0010586 | biological_process | miRNA metabolic process |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0031054 | biological_process | pre-miRNA processing |
| A | 0031123 | biological_process | RNA 3'-end processing |
| A | 0035198 | molecular_function | miRNA binding |
| A | 0050265 | molecular_function | RNA uridylyltransferase activity |
| A | 0070569 | molecular_function | uridylyltransferase activity |
| A | 0071044 | biological_process | histone mRNA catabolic process |
| A | 0141008 | biological_process | transposable element silencing by mRNA destabilization |
| A | 1990074 | biological_process | polyuridylation-dependent mRNA catabolic process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 49 |
| Details | Domain: {"description":"PAP-associated 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 17 |
| Details | Zinc finger: {"description":"CCHC-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00047","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 13 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"5W0N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W0O","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
