8OG1
Exostosin-like 3 apo enzyme
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0001888 | molecular_function | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006486 | biological_process | protein glycosylation |
| A | 0008375 | molecular_function | acetylglucosaminyltransferase activity |
| A | 0010838 | biological_process | positive regulation of keratinocyte proliferation |
| A | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016500 | molecular_function | protein-hormone receptor activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0030307 | biological_process | positive regulation of cell growth |
| A | 0045617 | biological_process | negative regulation of keratinocyte differentiation |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050728 | biological_process | negative regulation of inflammatory response |
| A | 0051897 | biological_process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| A | 0106015 | biological_process | negative regulation of inflammatory response to wounding |
| A | 1900016 | biological_process | negative regulation of cytokine production involved in inflammatory response |
| A | 2000972 | biological_process | positive regulation of detection of glucose |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 867 |
| Details | TOPO_DOM: Lumenal => ECO:0000255 |
| Chain | Residue | Details |
| A | THR52-ILE919 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:Q9ES89 |
| Chain | Residue | Details |
| A | ASP833 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:35676258, ECO:0007744|PDB:7AUA |
| Chain | Residue | Details |
| A | LEU668 | |
| A | ARG672 | |
| A | ASN697 | |
| A | ASP746 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q9ES89 |
| Chain | Residue | Details |
| A | ASN723 | |
| A | ARG728 | |
| A | ASP744 | |
| A | ASP745 | |
| A | GLU832 | |
| A | ASP833 | |
| A | ARG876 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | SITE: Not glycosylated => ECO:0000269|PubMed:29346724 |
| Chain | Residue | Details |
| A | ASN277 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9WVL6 |
| Chain | Residue | Details |
| A | SER362 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:29346724 |
| Chain | Residue | Details |
| A | ASN290 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:29346724, ECO:0000269|PubMed:35676258, ECO:0000312|PDB:7AUA, ECO:0007744|PDB:7AU2 |
| Chain | Residue | Details |
| A | ASN592 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:35676258, ECO:0000312|PDB:7AUA, ECO:0007744|PDB:7AU2 |
| Chain | Residue | Details |
| A | ASN790 |
