8OG1
Exostosin-like 3 apo enzyme
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0001888 | molecular_function | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006486 | biological_process | protein glycosylation |
| A | 0008375 | molecular_function | acetylglucosaminyltransferase activity |
| A | 0010838 | biological_process | positive regulation of keratinocyte proliferation |
| A | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016500 | molecular_function | protein-hormone receptor activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0030307 | biological_process | positive regulation of cell growth |
| A | 0043491 | biological_process | phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| A | 0045617 | biological_process | negative regulation of keratinocyte differentiation |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050728 | biological_process | negative regulation of inflammatory response |
| A | 0051897 | biological_process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| A | 0090594 | biological_process | inflammatory response to wounding |
| A | 0106015 | biological_process | negative regulation of inflammatory response to wounding |
| A | 1900016 | biological_process | negative regulation of cytokine production involved in inflammatory response |
| A | 1900017 | biological_process | positive regulation of cytokine production involved in inflammatory response |
| A | 2000972 | biological_process | positive regulation of detection of glucose |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"UniProtKB","id":"Q9ES89","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"35676258","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7AUA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9ES89","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Not glycosylated","evidences":[{"source":"PubMed","id":"29346724","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"29346724","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"29346724","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35676258","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7AUA","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7AU2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"35676258","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7AUA","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7AU2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
