8KH2

Crystal structure of horse-spleen L-ferritin fused with amyloid beta peptide (1-42).

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0005737	cellular_component	cytoplasm
A	0006879	biological_process	intracellular iron ion homeostasis
A	0006880	biological_process	intracellular sequestering of iron ion
A	0008043	cellular_component	intracellular ferritin complex
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEshFLdeevklIK

Chain	Residue	Details
A	ASP122-LYS142

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site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EkREgaERLLkmQNqRgGR

Chain	Residue	Details
A	GLU57-ARG75

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00085

Chain	Residue	Details
A	GLU53
A	GLU56
A	GLU57
A	GLU60
A	GLU63

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylserine => ECO:0000269|PubMed:7026284

Chain	Residue	Details
A	SER1

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P05067

Chain	Residue	Details
A	HIS183
A	TYR187
A	HIS190
A	HIS191

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site_id	SWS_FT_FI4
Number of Residues	1
Details	SITE: Cleavage; by ACE => ECO:0000250|UniProtKB:P05067

Chain	Residue	Details
A	ASP184

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