8K62

Crystal structure of ALKBH1 and 13h complex.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000791	cellular_component	euchromatin
A	0002101	biological_process	tRNA wobble cytosine modification
A	0003824	molecular_function	catalytic activity
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005759	cellular_component	mitochondrial matrix
A	0006281	biological_process	DNA repair
A	0006351	biological_process	DNA-templated transcription
A	0006417	biological_process	regulation of translation
A	0006446	biological_process	regulation of translational initiation
A	0006448	biological_process	regulation of translational elongation
A	0006974	biological_process	DNA damage response
A	0008198	molecular_function	ferrous iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0016829	molecular_function	lyase activity
A	0035513	biological_process	oxidative RNA demethylation
A	0035515	molecular_function	oxidative RNA demethylase activity
A	0035516	molecular_function	broad specificity oxidative DNA demethylase activity
A	0042056	molecular_function	chemoattractant activity
A	0042245	biological_process	RNA repair
A	0046872	molecular_function	metal ion binding
A	0050918	biological_process	positive chemotaxis
A	0051213	molecular_function	dioxygenase activity
A	0070129	biological_process	regulation of mitochondrial translation
A	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A	0141131	molecular_function	DNA N6-methyladenine demethylase activity
A	0141137	biological_process	positive regulation of gene expression, epigenetic
A	0160290	molecular_function	2-oxoglutarate-dependent tRNA 5-methylcytidine formyltransferase activity
A	1990983	biological_process	regulation of translational initiation by tRNA modification
A	1990984	molecular_function	tRNA demethylase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	139
Details	Domain: {"description":"Fe2OG dioxygenase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00805","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q6NS38","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q96Q83","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00805","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19959401","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27745969","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00805","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Site: {"description":"Secondary catalytic residue forming the imine linkage with DNA","evidences":[{"source":"PubMed","id":"23577621","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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