8K60
Cryo-EM structure of Streptomyces coelicolor transcription initiation complex with the global transcription factor AfsR
Functional Information from PROSITE/UniProt
| site_id | PS00715 |
| Number of Residues | 14 |
| Details | SIGMA70_1 Sigma-70 factors family signature 1. DLIQeGnLGLIrAV |
| Chain | Residue | Details |
| F | ASP302-VAL315 |
| site_id | PS00716 |
| Number of Residues | 27 |
| Details | SIGMA70_2 Sigma-70 factors family signature 2. TldEIGkvygVTrerIrQIEsktMskL |
| Chain | Residue | Details |
| F | THR471-LEU497 |
| site_id | PS00867 |
| Number of Residues | 8 |
| Details | CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. LLEANLRL |
| Chain | Residue | Details |
| F | LEU278-LEU285 |
| site_id | PS01166 |
| Number of Residues | 13 |
| Details | RNA_POL_BETA RNA polymerases beta chain signature. GdKLAGrHGNKGV |
| Chain | Residue | Details |
| C | GLY868-VAL880 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 192 |
| Details | DNA_BIND: OmpR/PhoB-type => ECO:0000255|PROSITE-ProRule:PRU01091 |
| Chain | Residue | Details |
| I | ALA17-GLY113 | |
| D | CYS969 | |
| D | CYS972 | |
| J | ALA17-GLY113 | |
| D | CYS75 | |
| D | CYS78 | |
| D | ASP535 | |
| D | ASP537 | |
| D | ASP539 | |
| D | CYS886 | |
| D | CYS962 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 58 |
| Details | DNA_BIND: H-T-H motif => ECO:0000255 |
| Chain | Residue | Details |
| I | GLN796-ALA811 | |
| I | GLN974-ALA988 | |
| J | GLN796-ALA811 | |
| J | GLN974-ALA988 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255 |
| Chain | Residue | Details |
| I | GLY330 | |
| J | GLY330 |
