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8JYJ

Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with laccaic acid A

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0004523molecular_functionRNA-DNA hybrid ribonuclease activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING:
ChainResidueDetails
AASP23
AASP78

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:12206668
ChainResidueDetails
AGLU58
AASP139

site_idSWS_FT_FI3
Number of Residues1
DetailsSITE: Cleavage; by viral protease; partial => ECO:0000250
ChainResidueDetails
APHE20

site_idSWS_FT_FI4
Number of Residues1
DetailsSITE: Cleavage; by viral protease => ECO:0000250
ChainResidueDetails
ALEU150

Catalytic Information from CSA
site_idMCSA1
Number of Residues
DetailsM-CSA 175
ChainResidueDetails

227111

PDB entries from 2024-11-06

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