8JNR
Crystal structure of human ALKBH3 bound to 3mC containing ssDNA through distal crosslink
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006281 | biological_process | DNA repair |
| A | 0006307 | biological_process | DNA alkylation repair |
| A | 0051213 | molecular_function | dioxygenase activity |
| C | 0006281 | biological_process | DNA repair |
| C | 0006307 | biological_process | DNA alkylation repair |
| C | 0051213 | molecular_function | dioxygenase activity |
| D | 0006281 | biological_process | DNA repair |
| D | 0006307 | biological_process | DNA alkylation repair |
| D | 0051213 | molecular_function | dioxygenase activity |
| E | 0006281 | biological_process | DNA repair |
| E | 0006307 | biological_process | DNA alkylation repair |
| E | 0051213 | molecular_function | dioxygenase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| K | TYR195-HIS201 | |
| G | TYR194-HIS200 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q6NS38 |
| Chain | Residue | Details |
| A | TRP115 | |
| E | TRP115 | |
| E | TYR141 | |
| E | ASP194 | |
| A | TYR141 | |
| A | ASP194 | |
| C | TRP115 | |
| C | TYR141 | |
| C | ASP194 | |
| D | TRP115 | |
| D | TYR141 | |
| D | ASP194 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16858410, ECO:0007744|PDB:2IUW |
| Chain | Residue | Details |
| A | ASN179 | |
| E | ASN179 | |
| E | ARG269 | |
| E | ARG275 | |
| A | ARG269 | |
| A | ARG275 | |
| C | ASN179 | |
| C | ARG269 | |
| C | ARG275 | |
| D | ASN179 | |
| D | ARG269 | |
| D | ARG275 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00805, ECO:0000269|PubMed:16858410, ECO:0007744|PDB:2IUW |
| Chain | Residue | Details |
| A | HIS191 | |
| E | HIS191 | |
| E | ASP193 | |
| E | HIS257 | |
| A | ASP193 | |
| A | HIS257 | |
| C | HIS191 | |
| C | ASP193 | |
| C | HIS257 | |
| D | HIS191 | |
| D | ASP193 | |
| D | HIS257 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: (4R)-5-oxoleucine; alternate => ECO:0000269|PubMed:16858410 |
| Chain | Residue | Details |
| A | LEU177 | |
| C | LEU177 | |
| D | LEU177 | |
| E | LEU177 |
