8JNR

Crystal structure of human ALKBH3 bound to 3mC containing ssDNA through distal crosslink

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006281	biological_process	DNA repair
A	0006307	biological_process	DNA alkylation repair
A	0051213	molecular_function	dioxygenase activity
C	0006281	biological_process	DNA repair
C	0006307	biological_process	DNA alkylation repair
C	0051213	molecular_function	dioxygenase activity
D	0006281	biological_process	DNA repair
D	0006307	biological_process	DNA alkylation repair
D	0051213	molecular_function	dioxygenase activity
E	0006281	biological_process	DNA repair
E	0006307	biological_process	DNA alkylation repair
E	0051213	molecular_function	dioxygenase activity

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
G	TYR194-HIS200
K	TYR195-HIS201

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	212
Details	Domain: {"description":"Fe2OG dioxygenase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00805","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q6NS38","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16858410","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2IUW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00805","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16858410","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2IUW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Modified residue: {"description":"(4R)-5-oxoleucine; alternate","evidences":[{"source":"PubMed","id":"16858410","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---