8JKT
Crystal structure of feline aminopeptidase N ectodomain
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VIAHELAHQW |
| Chain | Residue | Details |
| A | VAL321-TRP330 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:9782265 |
| Chain | Residue | Details |
| A | MET-62-SER-55 | |
| B | MET-62-SER-55 | |
| C | MET-62-SER-55 | |
| D | MET-62-SER-55 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 92 |
| Details | TRANSMEM: Helical; Signal-anchor for type II membrane protein => ECO:0000255 |
| Chain | Residue | Details |
| A | LYS-54-VAL-31 | |
| B | LYS-54-VAL-31 | |
| C | LYS-54-VAL-31 | |
| D | LYS-54-VAL-31 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3736 |
| Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:9634079, ECO:0000269|PubMed:9782265 |
| Chain | Residue | Details |
| A | TYR-30-SER904 | |
| B | TYR-30-SER904 | |
| C | TYR-30-SER904 | |
| D | TYR-30-SER904 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10095 |
| Chain | Residue | Details |
| A | GLU325 | |
| B | GLU325 | |
| C | GLU325 | |
| D | GLU325 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P15144 |
| Chain | Residue | Details |
| A | GLY288 | |
| B | GLY288 | |
| C | GLY288 | |
| D | GLY288 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU10095 |
| Chain | Residue | Details |
| A | HIS324 | |
| D | HIS324 | |
| D | HIS328 | |
| D | GLU347 | |
| A | HIS328 | |
| A | GLU347 | |
| B | HIS324 | |
| B | HIS328 | |
| B | GLU347 | |
| C | HIS324 | |
| C | HIS328 | |
| C | GLU347 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | SITE: Transition state stabilizer => ECO:0000250|UniProtKB:P15144 |
| Chain | Residue | Details |
| A | TYR413 | |
| B | TYR413 | |
| C | TYR413 | |
| D | TYR413 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 8 |
| Details | MOD_RES: Sulfotyrosine => ECO:0000255 |
| Chain | Residue | Details |
| A | TYR112 | |
| A | TYR355 | |
| B | TYR112 | |
| B | TYR355 | |
| C | TYR112 | |
| C | TYR355 | |
| D | TYR112 | |
| D | TYR355 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 32 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN-25 | |
| B | ASN21 | |
| B | ASN63 | |
| B | ASN170 | |
| B | ASN275 | |
| B | ASN563 | |
| B | ASN619 | |
| B | ASN677 | |
| C | ASN-25 | |
| C | ASN21 | |
| C | ASN63 | |
| A | ASN21 | |
| C | ASN170 | |
| C | ASN275 | |
| C | ASN563 | |
| C | ASN619 | |
| C | ASN677 | |
| D | ASN-25 | |
| D | ASN21 | |
| D | ASN63 | |
| D | ASN170 | |
| D | ASN275 | |
| A | ASN63 | |
| D | ASN563 | |
| D | ASN619 | |
| D | ASN677 | |
| A | ASN170 | |
| A | ASN275 | |
| A | ASN563 | |
| A | ASN619 | |
| A | ASN677 | |
| B | ASN-25 |
