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8JKQ

T95R mutant IRF4 DNA-binding domain bound to an DNA containing GACA motif

Functional Information from GO Data
ChainGOidnamespacecontents
D0000976molecular_functiontranscription cis-regulatory region binding
D0003700molecular_functionDNA-binding transcription factor activity
D0006355biological_processregulation of DNA-templated transcription
F0000976molecular_functiontranscription cis-regulatory region binding
F0003700molecular_functionDNA-binding transcription factor activity
F0006355biological_processregulation of DNA-templated transcription
G0000976molecular_functiontranscription cis-regulatory region binding
G0003700molecular_functionDNA-binding transcription factor activity
G0006355biological_processregulation of DNA-templated transcription
H0000976molecular_functiontranscription cis-regulatory region binding
H0003700molecular_functionDNA-binding transcription factor activity
H0006355biological_processregulation of DNA-templated transcription
Functional Information from PROSITE/UniProt
site_idPS00601
Number of Residues34
DetailsIRF_1 IRF tryptophan pentad repeat DNA-binding domain signature. WeNeeksiFrIPWkHagkqdynreeDaaLFKaWA
ChainResidueDetails
DTRP42-ALA75

226707

PDB entries from 2024-10-30

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