8JIB

Crystal Structure of Prophenoloxidase PPO6 from Aedes aegypti

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004097	molecular_function	catechol oxidase activity
A	0004497	molecular_function	monooxygenase activity
A	0004503	molecular_function	tyrosinase activity
A	0005576	cellular_component	extracellular region
A	0016491	molecular_function	oxidoreductase activity
A	0035011	biological_process	melanotic encapsulation of foreign target
A	0042417	biological_process	dopamine metabolic process
A	0042438	biological_process	melanin biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0004097	molecular_function	catechol oxidase activity
B	0004497	molecular_function	monooxygenase activity
B	0004503	molecular_function	tyrosinase activity
B	0005576	cellular_component	extracellular region
B	0016491	molecular_function	oxidoreductase activity
B	0035011	biological_process	melanotic encapsulation of foreign target
B	0042417	biological_process	dopamine metabolic process
B	0042438	biological_process	melanin biosynthetic process
B	0046872	molecular_function	metal ion binding
C	0004097	molecular_function	catechol oxidase activity
C	0004497	molecular_function	monooxygenase activity
C	0004503	molecular_function	tyrosinase activity
C	0005576	cellular_component	extracellular region
C	0016491	molecular_function	oxidoreductase activity
C	0035011	biological_process	melanotic encapsulation of foreign target
C	0042417	biological_process	dopamine metabolic process
C	0042438	biological_process	melanin biosynthetic process
C	0046872	molecular_function	metal ion binding
D	0004097	molecular_function	catechol oxidase activity
D	0004497	molecular_function	monooxygenase activity
D	0004503	molecular_function	tyrosinase activity
D	0005576	cellular_component	extracellular region
D	0016491	molecular_function	oxidoreductase activity
D	0035011	biological_process	melanotic encapsulation of foreign target
D	0042417	biological_process	dopamine metabolic process
D	0042438	biological_process	melanin biosynthetic process
D	0046872	molecular_function	metal ion binding
E	0004097	molecular_function	catechol oxidase activity
E	0004497	molecular_function	monooxygenase activity
E	0004503	molecular_function	tyrosinase activity
E	0005576	cellular_component	extracellular region
E	0016491	molecular_function	oxidoreductase activity
E	0035011	biological_process	melanotic encapsulation of foreign target
E	0042417	biological_process	dopamine metabolic process
E	0042438	biological_process	melanin biosynthetic process
E	0046872	molecular_function	metal ion binding
F	0004097	molecular_function	catechol oxidase activity
F	0004497	molecular_function	monooxygenase activity
F	0004503	molecular_function	tyrosinase activity
F	0005576	cellular_component	extracellular region
F	0016491	molecular_function	oxidoreductase activity
F	0035011	biological_process	melanotic encapsulation of foreign target
F	0042417	biological_process	dopamine metabolic process
F	0042438	biological_process	melanin biosynthetic process
F	0046872	molecular_function	metal ion binding
G	0004097	molecular_function	catechol oxidase activity
G	0004497	molecular_function	monooxygenase activity
G	0004503	molecular_function	tyrosinase activity
G	0005576	cellular_component	extracellular region
G	0016491	molecular_function	oxidoreductase activity
G	0035011	biological_process	melanotic encapsulation of foreign target
G	0042417	biological_process	dopamine metabolic process
G	0042438	biological_process	melanin biosynthetic process
G	0046872	molecular_function	metal ion binding
H	0004097	molecular_function	catechol oxidase activity
H	0004497	molecular_function	monooxygenase activity
H	0004503	molecular_function	tyrosinase activity
H	0005576	cellular_component	extracellular region
H	0016491	molecular_function	oxidoreductase activity
H	0035011	biological_process	melanotic encapsulation of foreign target
H	0042417	biological_process	dopamine metabolic process
H	0042438	biological_process	melanin biosynthetic process
H	0046872	molecular_function	metal ion binding
I	0004097	molecular_function	catechol oxidase activity
I	0004497	molecular_function	monooxygenase activity
I	0004503	molecular_function	tyrosinase activity
I	0005576	cellular_component	extracellular region
I	0016491	molecular_function	oxidoreductase activity
I	0035011	biological_process	melanotic encapsulation of foreign target
I	0042417	biological_process	dopamine metabolic process
I	0042438	biological_process	melanin biosynthetic process
I	0046872	molecular_function	metal ion binding
J	0004097	molecular_function	catechol oxidase activity
J	0004497	molecular_function	monooxygenase activity
J	0004503	molecular_function	tyrosinase activity
J	0005576	cellular_component	extracellular region
J	0016491	molecular_function	oxidoreductase activity
J	0035011	biological_process	melanotic encapsulation of foreign target
J	0042417	biological_process	dopamine metabolic process
J	0042438	biological_process	melanin biosynthetic process
J	0046872	molecular_function	metal ion binding
K	0004097	molecular_function	catechol oxidase activity
K	0004497	molecular_function	monooxygenase activity
K	0004503	molecular_function	tyrosinase activity
K	0005576	cellular_component	extracellular region
K	0016491	molecular_function	oxidoreductase activity
K	0035011	biological_process	melanotic encapsulation of foreign target
K	0042417	biological_process	dopamine metabolic process
K	0042438	biological_process	melanin biosynthetic process
K	0046872	molecular_function	metal ion binding
L	0004097	molecular_function	catechol oxidase activity
L	0004497	molecular_function	monooxygenase activity
L	0004503	molecular_function	tyrosinase activity
L	0005576	cellular_component	extracellular region
L	0016491	molecular_function	oxidoreductase activity
L	0035011	biological_process	melanotic encapsulation of foreign target
L	0042417	biological_process	dopamine metabolic process
L	0042438	biological_process	melanin biosynthetic process
L	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00209
Number of Residues	20
Details	HEMOCYANIN_1 Arthropod hemocyanins / insect LSPs signature 1. YFrEDIgvNlhhwhwHlvyP

Chain	Residue	Details
A	TYR195-PRO214

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site_id	PS00210
Number of Residues	9
Details	HEMOCYANIN_2 Arthropod hemocyanins / insect LSPs signature 2. TamRDPvFY

Chain	Residue	Details
A	THR392-TYR400

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site_id	PS00498
Number of Residues	12
Details	TYROSINASE_2 Tyrosinase and hemocyanins CuB-binding region signature. DPvFYrwHsfiD

Chain	Residue	Details
A	ASP396-ASP407

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