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8JBG

Neurokinin B bound to active human neurokinin 3 receptor in complex with Gq

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
B0004930molecular_functionG protein-coupled receptor activity
B0005506molecular_functioniron ion binding
B0007186biological_processG protein-coupled receptor signaling pathway
B0008643biological_processcarbohydrate transport
B0009055molecular_functionelectron transfer activity
B0015144molecular_functioncarbohydrate transmembrane transporter activity
B0016020cellular_componentmembrane
B0020037molecular_functionheme binding
B0022900biological_processelectron transport chain
B0042597cellular_componentperiplasmic space
B0055085biological_processtransmembrane transport
C0003924molecular_functionGTPase activity
C0005525molecular_functionGTP binding
C0007165biological_processsignal transduction
C0007186biological_processG protein-coupled receptor signaling pathway
C0019001molecular_functionguanyl nucleotide binding
C0031683molecular_functionG-protein beta/gamma-subunit complex binding
D0001750cellular_componentphotoreceptor outer segment
D0001917cellular_componentphotoreceptor inner segment
D0003924molecular_functionGTPase activity
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0005834cellular_componentheterotrimeric G-protein complex
D0005886cellular_componentplasma membrane
D0007165biological_processsignal transduction
D0007186biological_processG protein-coupled receptor signaling pathway
D0007200biological_processphospholipase C-activating G protein-coupled receptor signaling pathway
D0007204biological_processpositive regulation of cytosolic calcium ion concentration
D0008283biological_processcell population proliferation
D0010659biological_processcardiac muscle cell apoptotic process
D0030159molecular_functionsignaling receptor complex adaptor activity
D0030425cellular_componentdendrite
D0030507molecular_functionspectrin binding
D0042622cellular_componentphotoreceptor outer segment membrane
D0044297cellular_componentcell body
D0044877molecular_functionprotein-containing complex binding
D0045202cellular_componentsynapse
D0047391molecular_functionalkylglycerophosphoethanolamine phosphodiesterase activity
D0050909biological_processsensory perception of taste
D0051020molecular_functionGTPase binding
D0060041biological_processretina development in camera-type eye
D0071456biological_processcellular response to hypoxia
G0003924molecular_functionGTPase activity
G0005515molecular_functionprotein binding
G0005834cellular_componentheterotrimeric G-protein complex
G0005886cellular_componentplasma membrane
G0007165biological_processsignal transduction
G0007186biological_processG protein-coupled receptor signaling pathway
G0007191biological_processadenylate cyclase-activating dopamine receptor signaling pathway
G0016020cellular_componentmembrane
G0031681molecular_functionG-protein beta-subunit binding
G0071380biological_processcellular response to prostaglandin E stimulus
G0071870biological_processcellular response to catecholamine stimulus
Functional Information from PROSITE/UniProt
site_idPS00237
Number of Residues17
DetailsG_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. ASIySMTAIAVDRYMaI
ChainResidueDetails
BALA171-ILE187

site_idPS00267
Number of Residues5
DetailsTACHYKININ Tachykinin family signature. FVGLM
ChainResidueDetails
APHE6-MET10

site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSAsqDgKLIIWDS
ChainResidueDetails
DLEU70-SER84
DILE157-ILE171
DLEU285-ALA299
DVAL327-GLY341

site_idPS01037
Number of Residues18
DetailsSBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN
ChainResidueDetails
BPRO676-ASN693
BPRO1043-ASN1060

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues136
DetailsTOPO_DOM: Extracellular => ECO:0000255
ChainResidueDetails
BMET1-ARG84
BLEU140-ARG159
BLYS223-PHE245
BTHR322-ILE334

site_idSWS_FT_FI2
Number of Residues22
DetailsTRANSMEM: Helical; Name=1 => ECO:0000255
ChainResidueDetails
BILE85-ILE107

site_idSWS_FT_FI3
Number of Residues56
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
BTRP108-ARG117
BASP182-LYS201
BGLY271-LYS299

site_idSWS_FT_FI4
Number of Residues21
DetailsTRANSMEM: Helical; Name=2 => ECO:0000255
ChainResidueDetails
BTHR118-THR139

site_idSWS_FT_FI5
Number of Residues21
DetailsTRANSMEM: Helical; Name=3 => ECO:0000255
ChainResidueDetails
BPHE160-VAL181

site_idSWS_FT_FI6
Number of Residues20
DetailsTRANSMEM: Helical; Name=4 => ECO:0000255
ChainResidueDetails
BILE202-SER222

site_idSWS_FT_FI7
Number of Residues24
DetailsTRANSMEM: Helical; Name=5 => ECO:0000255
ChainResidueDetails
BTHR246-VAL270

site_idSWS_FT_FI8
Number of Residues21
DetailsTRANSMEM: Helical; Name=6 => ECO:0000255
ChainResidueDetails
BMET300-LEU321

site_idSWS_FT_FI9
Number of Residues24
DetailsTRANSMEM: Helical; Name=7 => ECO:0000255
ChainResidueDetails
BGLN335-LEU359

site_idSWS_FT_FI10
Number of Residues1
DetailsLIPID: S-palmitoyl cysteine => ECO:0000255
ChainResidueDetails
BCYS374

site_idSWS_FT_FI11
Number of Residues3
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
BASN23
BASN50
BASN73

227111

PDB entries from 2024-11-06

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