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8J7U

Cryo-EM structure of hZnT7-Fab complex in zinc-bound state, determined in outward-facing conformation

Functional Information from GO Data
ChainGOidnamespacecontents
A0000139cellular_componentGolgi membrane
A0005385molecular_functionzinc ion transmembrane transporter activity
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005794cellular_componentGolgi apparatus
A0006812biological_processmonoatomic cation transport
A0006829biological_processzinc ion transport
A0006882biological_processintracellular zinc ion homeostasis
A0008324molecular_functionmonoatomic cation transmembrane transporter activity
A0016020cellular_componentmembrane
A0016529cellular_componentsarcoplasmic reticulum
A0031410cellular_componentcytoplasmic vesicle
A0031982cellular_componentvesicle
A0033017cellular_componentsarcoplasmic reticulum membrane
A0042802molecular_functionidentical protein binding
A0048471cellular_componentperinuclear region of cytoplasm
A0055085biological_processtransmembrane transport
A0071577biological_processzinc ion transmembrane transport
A1904257biological_processzinc ion import into Golgi lumen
A1990674cellular_componentGolgi cis cisterna membrane
B0000139cellular_componentGolgi membrane
B0005385molecular_functionzinc ion transmembrane transporter activity
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005794cellular_componentGolgi apparatus
B0006812biological_processmonoatomic cation transport
B0006829biological_processzinc ion transport
B0006882biological_processintracellular zinc ion homeostasis
B0008324molecular_functionmonoatomic cation transmembrane transporter activity
B0016020cellular_componentmembrane
B0016529cellular_componentsarcoplasmic reticulum
B0031410cellular_componentcytoplasmic vesicle
B0031982cellular_componentvesicle
B0033017cellular_componentsarcoplasmic reticulum membrane
B0042802molecular_functionidentical protein binding
B0048471cellular_componentperinuclear region of cytoplasm
B0055085biological_processtransmembrane transport
B0071577biological_processzinc ion transmembrane transport
B1904257biological_processzinc ion import into Golgi lumen
B1990674cellular_componentGolgi cis cisterna membrane
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
ChainResidueDetails
CTYR196-HIS202

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues430
DetailsTOPO_DOM: Cytoplasmic => ECO:0000305
ChainResidueDetails
AMET1-ASN37
ALYS89-ARG102
AGLY162-GLY236
APRO284-MET376
BMET1-ASN37
BLYS89-ARG102
BGLY162-GLY236
BPRO284-MET376

site_idSWS_FT_FI2
Number of Residues240
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
ALEU38-TRP58
BLEU141-HIS161
BVAL237-MET257
BLEU263-ILE283
ASER68-SER88
AALA103-PHE123
ALEU141-HIS161
AVAL237-MET257
ALEU263-ILE283
BLEU38-TRP58
BSER68-SER88
BALA103-PHE123

site_idSWS_FT_FI3
Number of Residues56
DetailsTOPO_DOM: Lumenal => ECO:0000305
ChainResidueDetails
ASER59-ASP67
ASER124-ARG140
AMET258-GLY262
BSER59-ASP67
BSER124-ARG140
BMET258-GLY262

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PDB entries from 2024-10-30

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