8J54
Crystal structure of RXR/DR2 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0043565 | molecular_function | sequence-specific DNA binding |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0043565 | molecular_function | sequence-specific DNA binding |
| E | 0003700 | molecular_function | DNA-binding transcription factor activity |
| E | 0006355 | biological_process | regulation of DNA-templated transcription |
| E | 0008270 | molecular_function | zinc ion binding |
| E | 0043565 | molecular_function | sequence-specific DNA binding |
| F | 0003700 | molecular_function | DNA-binding transcription factor activity |
| F | 0006355 | biological_process | regulation of DNA-templated transcription |
| F | 0008270 | molecular_function | zinc ion binding |
| F | 0043565 | molecular_function | sequence-specific DNA binding |
Functional Information from PROSITE/UniProt
| site_id | PS00031 |
| Number of Residues | 27 |
| Details | NUCLEAR_REC_DBD_1 Nuclear hormones receptors DNA-binding region signature. CaiCg.Drssgk.HYgvysCegCkgFFkR |
| Chain | Residue | Details |
| C | CYS139-ARG165 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 260 |
| Details | DNA_BIND: Nuclear receptor => ECO:0000255|PROSITE-ProRule:PRU00407 |
| Chain | Residue | Details |
| C | CYS139-MET204 | |
| D | CYS139-MET204 | |
| E | CYS139-MET204 | |
| F | CYS139-MET204 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 176 |
| Details | ZN_FING: NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407 |
| Chain | Residue | Details |
| C | CYS139-CYS159 | |
| C | CYS175-CYS199 | |
| D | CYS139-CYS159 | |
| D | CYS175-CYS199 | |
| E | CYS139-CYS159 | |
| E | CYS175-CYS199 | |
| F | CYS139-CYS159 | |
| F | CYS175-CYS199 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P19793 |
| Chain | Residue | Details |
| C | CYS139 | |
| D | CYS142 | |
| D | CYS156 | |
| D | CYS159 | |
| D | CYS175 | |
| D | CYS181 | |
| D | CYS191 | |
| D | CYS194 | |
| E | CYS139 | |
| E | CYS142 | |
| E | CYS156 | |
| C | CYS142 | |
| E | CYS159 | |
| E | CYS175 | |
| E | CYS181 | |
| E | CYS191 | |
| E | CYS194 | |
| F | CYS139 | |
| F | CYS142 | |
| F | CYS156 | |
| F | CYS159 | |
| F | CYS175 | |
| C | CYS156 | |
| F | CYS181 | |
| F | CYS191 | |
| F | CYS194 | |
| C | CYS159 | |
| C | CYS175 | |
| C | CYS181 | |
| C | CYS191 | |
| C | CYS194 | |
| D | CYS139 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P19793 |
| Chain | Residue | Details |
| C | LYS149 | |
| D | LYS149 | |
| E | LYS149 | |
| F | LYS149 |
