8J12
Cryo-EM structure of the AsCas12f-sgRNA-target DNA ternary complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:A0A482D308 |
| Chain | Residue | Details |
| A | ASP225 | |
| A | GLU324 | |
| A | ASP401 | |
| B | ASP225 | |
| B | GLU324 | |
| B | ASP401 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:A0A482D308 |
| Chain | Residue | Details |
| A | CYS372 | |
| A | CYS375 | |
| A | CYS391 | |
| A | CYS394 | |
| B | CYS372 | |
| B | CYS375 | |
| B | CYS391 | |
| B | CYS394 |
