8IQL

Structural basis of the specificity and interaction mechanism of Bmf binding to pro-survival proteins

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0042981	biological_process	regulation of apoptotic process
A	0043066	biological_process	negative regulation of apoptotic process
B	0006915	biological_process	apoptotic process
C	0042981	biological_process	regulation of apoptotic process
C	0043066	biological_process	negative regulation of apoptotic process
D	0006915	biological_process	apoptotic process

Functional Information from PROSITE/UniProt

site_id	PS01080
Number of Residues	19
Details	BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFeFGG

Chain	Residue	Details
C	LEU137-GLY155

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site_id	PS01258
Number of Residues	12
Details	BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqdnGGWDaFV

Chain	Residue	Details
C	TRP188-VAL199

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site_id	PS01259
Number of Residues	15
Details	BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VhltLRqAGDDFSRR

Chain	Residue	Details
C	VAL93-ARG107

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site_id	PS01260
Number of Residues	21
Details	BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. DNREIVmKYIHYKLSQRGYeW

Chain	Residue	Details
C	ASP10-TRP30

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Cleavage; by caspase-3

Chain	Residue	Details
C	ASP75
A	ASP75

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphothreonine; by MAPK8 => ECO:0000269|PubMed:18570871

Chain	Residue	Details
C	LEU95
A	LEU95

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphoserine; by MAPK8 and PKC => ECO:0000269|PubMed:18570871

Chain	Residue	Details
C	THR96
A	THR96

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site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: Phosphoserine; by MAPK8 => ECO:0000269|PubMed:18570871

Chain	Residue	Details
C	ALA113
A	ALA113

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