8IPY

human nuclear pre-60S ribosomal particle - State D'

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
1	0001825	biological_process	blastocyst formation
1	0003723	molecular_function	RNA binding
1	0003735	molecular_function	structural constituent of ribosome
1	0005515	molecular_function	protein binding
1	0005730	cellular_component	nucleolus
1	0005739	cellular_component	mitochondrion
1	0005840	cellular_component	ribosome
1	0022625	cellular_component	cytosolic large ribosomal subunit
1	1990904	cellular_component	ribonucleoprotein complex
4	0000166	molecular_function	nucleotide binding
4	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
4	0001649	biological_process	osteoblast differentiation
4	0003723	molecular_function	RNA binding
4	0003924	molecular_function	GTPase activity
4	0005515	molecular_function	protein binding
4	0005525	molecular_function	GTP binding
4	0005634	cellular_component	nucleus
4	0005654	cellular_component	nucleoplasm
4	0005730	cellular_component	nucleolus
4	0005737	cellular_component	cytoplasm
4	0005829	cellular_component	cytosol
4	0008156	biological_process	negative regulation of DNA replication
4	0008285	biological_process	negative regulation of cell population proliferation
4	0010972	biological_process	negative regulation of G2/M transition of mitotic cell cycle
4	0016020	cellular_component	membrane
4	0022408	biological_process	negative regulation of cell-cell adhesion
4	0030336	biological_process	negative regulation of cell migration
4	0031397	biological_process	negative regulation of protein ubiquitination
4	0031965	cellular_component	nuclear membrane
4	0042254	biological_process	ribosome biogenesis
4	0042273	biological_process	ribosomal large subunit biogenesis
4	0048471	cellular_component	perinuclear region of cytoplasm
4	0050821	biological_process	protein stabilization
4	1990275	molecular_function	preribosome binding
6	0000054	biological_process	ribosomal subunit export from nucleus
6	0000460	biological_process	maturation of 5.8S rRNA
6	0000470	biological_process	maturation of LSU-rRNA
6	0003743	molecular_function	translation initiation factor activity
6	0005515	molecular_function	protein binding
6	0005634	cellular_component	nucleus
6	0005638	cellular_component	lamin filament
6	0005654	cellular_component	nucleoplasm
6	0005730	cellular_component	nucleolus
6	0005737	cellular_component	cytoplasm
6	0005829	cellular_component	cytosol
6	0005882	cellular_component	intermediate filament
6	0006110	biological_process	regulation of glycolytic process
6	0006412	biological_process	translation
6	0006413	biological_process	translational initiation
6	0032868	biological_process	response to insulin
6	0035195	biological_process	miRNA-mediated post-transcriptional gene silencing
6	0035278	biological_process	miRNA-mediated gene silencing by inhibition of translation
6	0042254	biological_process	ribosome biogenesis
6	0042256	biological_process	cytosolic ribosome assembly
6	0042273	biological_process	ribosomal large subunit biogenesis
6	0042304	biological_process	regulation of fatty acid biosynthetic process
6	0043022	molecular_function	ribosome binding
6	0043023	molecular_function	ribosomal large subunit binding
6	0045202	cellular_component	synapse
6	0045652	biological_process	regulation of megakaryocyte differentiation
6	0045727	biological_process	positive regulation of translation
6	0070062	cellular_component	extracellular exosome
6	1902626	biological_process	assembly of large subunit precursor of preribosome
6	2000377	biological_process	regulation of reactive oxygen species metabolic process
7	0003735	molecular_function	structural constituent of ribosome
7	0005515	molecular_function	protein binding
7	0005654	cellular_component	nucleoplasm
7	0005730	cellular_component	nucleolus
7	0042254	biological_process	ribosome biogenesis
7	0042273	biological_process	ribosomal large subunit biogenesis
9	0003676	molecular_function	nucleic acid binding
9	0003677	molecular_function	DNA binding
9	0005515	molecular_function	protein binding
9	0005634	cellular_component	nucleus
9	0005654	cellular_component	nucleoplasm
9	0005730	cellular_component	nucleolus
9	0005737	cellular_component	cytoplasm
9	0008270	molecular_function	zinc ion binding
9	0042254	biological_process	ribosome biogenesis
9	0043021	molecular_function	ribonucleoprotein complex binding
9	0045944	biological_process	positive regulation of transcription by RNA polymerase II
9	0046872	molecular_function	metal ion binding
9	1903026	biological_process	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
9	1990275	molecular_function	preribosome binding
A	0002181	biological_process	cytoplasmic translation
A	0003723	molecular_function	RNA binding
A	0003735	molecular_function	structural constituent of ribosome
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005840	cellular_component	ribosome
A	0006412	biological_process	translation
A	0007566	biological_process	embryo implantation
A	0008201	molecular_function	heparin binding
A	0016020	cellular_component	membrane
A	0022625	cellular_component	cytosolic large ribosomal subunit
A	0022626	cellular_component	cytosolic ribosome
A	0045296	molecular_function	cadherin binding
A	1990904	cellular_component	ribonucleoprotein complex
B	0002181	biological_process	cytoplasmic translation
B	0003723	molecular_function	RNA binding
B	0003735	molecular_function	structural constituent of ribosome
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005730	cellular_component	nucleolus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005840	cellular_component	ribosome
B	0005925	cellular_component	focal adhesion
B	0006412	biological_process	translation
B	0022625	cellular_component	cytosolic large ribosomal subunit
B	0022626	cellular_component	cytosolic ribosome
B	0032991	cellular_component	protein-containing complex
B	0070062	cellular_component	extracellular exosome
B	0071353	biological_process	cellular response to interleukin-4
B	1990904	cellular_component	ribonucleoprotein complex
C	0000027	biological_process	ribosomal large subunit assembly
C	0002181	biological_process	cytoplasmic translation
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005515	molecular_function	protein binding
C	0005654	cellular_component	nucleoplasm
C	0005730	cellular_component	nucleolus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005840	cellular_component	ribosome
C	0006364	biological_process	rRNA processing
C	0006412	biological_process	translation
C	0006605	biological_process	protein targeting
C	0008097	molecular_function	5S rRNA binding
C	0016020	cellular_component	membrane
C	0019843	molecular_function	rRNA binding
C	0022625	cellular_component	cytosolic large ribosomal subunit
C	0022626	cellular_component	cytosolic ribosome
C	0031625	molecular_function	ubiquitin protein ligase binding
C	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
C	0032991	cellular_component	protein-containing complex
C	0034504	biological_process	protein localization to nucleus
C	0042273	biological_process	ribosomal large subunit biogenesis
C	0070062	cellular_component	extracellular exosome
C	1901796	biological_process	regulation of signal transduction by p53 class mediator
C	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
C	1990904	cellular_component	ribonucleoprotein complex
C	1990948	molecular_function	ubiquitin ligase inhibitor activity
C	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
D	0002181	biological_process	cytoplasmic translation
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005730	cellular_component	nucleolus
D	0005737	cellular_component	cytoplasm
D	0005783	cellular_component	endoplasmic reticulum
D	0005791	cellular_component	rough endoplasmic reticulum
D	0005829	cellular_component	cytosol
D	0005840	cellular_component	ribosome
D	0005925	cellular_component	focal adhesion
D	0006412	biological_process	translation
D	0016020	cellular_component	membrane
D	0016604	cellular_component	nuclear body
D	0022625	cellular_component	cytosolic large ribosomal subunit
D	0022626	cellular_component	cytosolic ribosome
D	0070062	cellular_component	extracellular exosome
D	1990904	cellular_component	ribonucleoprotein complex
E	0002181	biological_process	cytoplasmic translation
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005840	cellular_component	ribosome
E	0005925	cellular_component	focal adhesion
E	0006412	biological_process	translation
E	0014069	cellular_component	postsynaptic density
E	0016020	cellular_component	membrane
E	0022625	cellular_component	cytosolic large ribosomal subunit
E	0022626	cellular_component	cytosolic ribosome
E	0031640	biological_process	killing of cells of another organism
E	0045202	cellular_component	synapse
E	0050829	biological_process	defense response to Gram-negative bacterium
E	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
E	0070062	cellular_component	extracellular exosome
E	1990904	cellular_component	ribonucleoprotein complex
F	0002181	biological_process	cytoplasmic translation
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005515	molecular_function	protein binding
F	0005730	cellular_component	nucleolus
F	0005737	cellular_component	cytoplasm
F	0005783	cellular_component	endoplasmic reticulum
F	0005829	cellular_component	cytosol
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0022625	cellular_component	cytosolic large ribosomal subunit
F	0022626	cellular_component	cytosolic ribosome
F	0045202	cellular_component	synapse
F	0045296	molecular_function	cadherin binding
F	0070062	cellular_component	extracellular exosome
F	1990904	cellular_component	ribonucleoprotein complex
G	0000470	biological_process	maturation of LSU-rRNA
G	0002181	biological_process	cytoplasmic translation
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005730	cellular_component	nucleolus
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005840	cellular_component	ribosome
G	0005925	cellular_component	focal adhesion
G	0006412	biological_process	translation
G	0016020	cellular_component	membrane
G	0022625	cellular_component	cytosolic large ribosomal subunit
G	0022626	cellular_component	cytosolic ribosome
G	0042254	biological_process	ribosome biogenesis
G	0045202	cellular_component	synapse
G	0045296	molecular_function	cadherin binding
G	1990904	cellular_component	ribonucleoprotein complex
H	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H	0002181	biological_process	cytoplasmic translation
H	0003723	molecular_function	RNA binding
H	0003729	molecular_function	mRNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005730	cellular_component	nucleolus
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0015934	cellular_component	large ribosomal subunit
H	0016020	cellular_component	membrane
H	0022625	cellular_component	cytosolic large ribosomal subunit
H	0022626	cellular_component	cytosolic ribosome
H	1990904	cellular_component	ribonucleoprotein complex
I	0002181	biological_process	cytoplasmic translation
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005840	cellular_component	ribosome
I	0005925	cellular_component	focal adhesion
I	0006412	biological_process	translation
I	0016020	cellular_component	membrane
I	0019843	molecular_function	rRNA binding
I	0022625	cellular_component	cytosolic large ribosomal subunit
I	0022626	cellular_component	cytosolic ribosome
I	1990904	cellular_component	ribonucleoprotein complex
J	0000460	biological_process	maturation of 5.8S rRNA
J	0000470	biological_process	maturation of LSU-rRNA
J	0003723	molecular_function	RNA binding
J	0005730	cellular_component	nucleolus
J	0006364	biological_process	rRNA processing
J	0030684	cellular_component	preribosome
J	0030687	cellular_component	preribosome, large subunit precursor
J	0042254	biological_process	ribosome biogenesis
J	0042273	biological_process	ribosomal large subunit biogenesis
J	1990904	cellular_component	ribonucleoprotein complex
K	0002181	biological_process	cytoplasmic translation
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005515	molecular_function	protein binding
K	0005730	cellular_component	nucleolus
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0016020	cellular_component	membrane
K	0022625	cellular_component	cytosolic large ribosomal subunit
K	0022626	cellular_component	cytosolic ribosome
K	0045202	cellular_component	synapse
K	1990904	cellular_component	ribonucleoprotein complex
L	0002181	biological_process	cytoplasmic translation
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005515	molecular_function	protein binding
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005783	cellular_component	endoplasmic reticulum
L	0005829	cellular_component	cytosol
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0015934	cellular_component	large ribosomal subunit
L	0016020	cellular_component	membrane
L	0022625	cellular_component	cytosolic large ribosomal subunit
L	0022626	cellular_component	cytosolic ribosome
L	0045202	cellular_component	synapse
L	1990904	cellular_component	ribonucleoprotein complex
M	0002181	biological_process	cytoplasmic translation
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0008270	molecular_function	zinc ion binding
M	0019843	molecular_function	rRNA binding
M	0022625	cellular_component	cytosolic large ribosomal subunit
M	0022626	cellular_component	cytosolic ribosome
M	0045202	cellular_component	synapse
M	0046872	molecular_function	metal ion binding
M	0097371	molecular_function	MDM2/MDM4 family protein binding
M	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
M	1990904	cellular_component	ribonucleoprotein complex
M	1990948	molecular_function	ubiquitin ligase inhibitor activity
N	0000055	biological_process	ribosomal large subunit export from nucleus
N	0005654	cellular_component	nucleoplasm
N	0005730	cellular_component	nucleolus
N	0015031	biological_process	protein transport
N	0042254	biological_process	ribosome biogenesis
N	0042273	biological_process	ribosomal large subunit biogenesis
O	0001501	biological_process	skeletal system development
O	0001503	biological_process	ossification
O	0002181	biological_process	cytoplasmic translation
O	0003723	molecular_function	RNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005515	molecular_function	protein binding
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005840	cellular_component	ribosome
O	0005925	cellular_component	focal adhesion
O	0006412	biological_process	translation
O	0006417	biological_process	regulation of translation
O	0007605	biological_process	sensory perception of sound
O	0014069	cellular_component	postsynaptic density
O	0022618	biological_process	protein-RNA complex assembly
O	0022625	cellular_component	cytosolic large ribosomal subunit
O	0022626	cellular_component	cytosolic ribosome
O	0033291	cellular_component	eukaryotic 80S initiation complex
O	0034463	biological_process	90S preribosome assembly
O	0042474	biological_process	middle ear morphogenesis
O	0045202	cellular_component	synapse
O	0048318	biological_process	axial mesoderm development
O	1990904	cellular_component	ribonucleoprotein complex
P	0002181	biological_process	cytoplasmic translation
P	0002227	biological_process	innate immune response in mucosa
P	0003723	molecular_function	RNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005615	cellular_component	extracellular space
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0019731	biological_process	antibacterial humoral response
P	0022625	cellular_component	cytosolic large ribosomal subunit
P	0022626	cellular_component	cytosolic ribosome
P	0050830	biological_process	defense response to Gram-positive bacterium
P	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
P	1990904	cellular_component	ribonucleoprotein complex
Q	0001824	biological_process	blastocyst development
Q	0002181	biological_process	cytoplasmic translation
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005730	cellular_component	nucleolus
Q	0005737	cellular_component	cytoplasm
Q	0005783	cellular_component	endoplasmic reticulum
Q	0005829	cellular_component	cytosol
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0016020	cellular_component	membrane
Q	0022625	cellular_component	cytosolic large ribosomal subunit
Q	0022626	cellular_component	cytosolic ribosome
Q	0045202	cellular_component	synapse
Q	0060348	biological_process	bone development
Q	1990904	cellular_component	ribonucleoprotein complex
R	0000027	biological_process	ribosomal large subunit assembly
R	0002181	biological_process	cytoplasmic translation
R	0003723	molecular_function	RNA binding
R	0003730	molecular_function	mRNA 3'-UTR binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005730	cellular_component	nucleolus
R	0005737	cellular_component	cytoplasm
R	0005783	cellular_component	endoplasmic reticulum
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0005925	cellular_component	focal adhesion
R	0006364	biological_process	rRNA processing
R	0006412	biological_process	translation
R	0008097	molecular_function	5S rRNA binding
R	0016020	cellular_component	membrane
R	0019843	molecular_function	rRNA binding
R	0022625	cellular_component	cytosolic large ribosomal subunit
R	0022626	cellular_component	cytosolic ribosome
R	0031625	molecular_function	ubiquitin protein ligase binding
R	0032991	cellular_component	protein-containing complex
R	0042273	biological_process	ribosomal large subunit biogenesis
R	0045727	biological_process	positive regulation of translation
R	0048027	molecular_function	mRNA 5'-UTR binding
R	0070062	cellular_component	extracellular exosome
R	1901796	biological_process	regulation of signal transduction by p53 class mediator
R	1990904	cellular_component	ribonucleoprotein complex
R	1990948	molecular_function	ubiquitin ligase inhibitor activity
R	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
S	0002181	biological_process	cytoplasmic translation
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005515	molecular_function	protein binding
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006364	biological_process	rRNA processing
S	0006412	biological_process	translation
S	0014069	cellular_component	postsynaptic density
S	0015934	cellular_component	large ribosomal subunit
S	0016020	cellular_component	membrane
S	0022625	cellular_component	cytosolic large ribosomal subunit
S	0022626	cellular_component	cytosolic ribosome
S	0042273	biological_process	ribosomal large subunit biogenesis
S	0045296	molecular_function	cadherin binding
S	0070062	cellular_component	extracellular exosome
S	1990904	cellular_component	ribonucleoprotein complex
T	0002181	biological_process	cytoplasmic translation
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005515	molecular_function	protein binding
T	0005737	cellular_component	cytoplasm
T	0005783	cellular_component	endoplasmic reticulum
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0016020	cellular_component	membrane
T	0022625	cellular_component	cytosolic large ribosomal subunit
T	0022626	cellular_component	cytosolic ribosome
T	0045202	cellular_component	synapse
T	1990904	cellular_component	ribonucleoprotein complex
U	0002181	biological_process	cytoplasmic translation
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0022625	cellular_component	cytosolic large ribosomal subunit
U	0022626	cellular_component	cytosolic ribosome
U	0044391	cellular_component	ribosomal subunit
U	0045202	cellular_component	synapse
U	0045296	molecular_function	cadherin binding
U	1990904	cellular_component	ribonucleoprotein complex
V	0002181	biological_process	cytoplasmic translation
V	0003723	molecular_function	RNA binding
V	0003729	molecular_function	mRNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005634	cellular_component	nucleus
V	0005730	cellular_component	nucleolus
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005840	cellular_component	ribosome
V	0005925	cellular_component	focal adhesion
V	0006412	biological_process	translation
V	0006417	biological_process	regulation of translation
V	0015934	cellular_component	large ribosomal subunit
V	0016020	cellular_component	membrane
V	0017148	biological_process	negative regulation of translation
V	0022625	cellular_component	cytosolic large ribosomal subunit
V	0022626	cellular_component	cytosolic ribosome
V	0032496	biological_process	response to lipopolysaccharide
V	0032819	biological_process	positive regulation of natural killer cell proliferation
V	0042592	biological_process	homeostatic process
V	0045202	cellular_component	synapse
V	0048246	biological_process	macrophage chemotaxis
V	0060425	biological_process	lung morphogenesis
V	0071346	biological_process	cellular response to type II interferon
V	0097452	cellular_component	GAIT complex
V	1901194	biological_process	negative regulation of formation of translation preinitiation complex
V	1990904	cellular_component	ribonucleoprotein complex
W	0000278	biological_process	mitotic cell cycle
W	0001756	biological_process	somitogenesis
W	0001822	biological_process	kidney development
W	0001826	biological_process	inner cell mass cell differentiation
W	0005515	molecular_function	protein binding
W	0005654	cellular_component	nucleoplasm
W	0005730	cellular_component	nucleolus
W	0007219	biological_process	Notch signaling pathway
W	0008593	biological_process	regulation of Notch signaling pathway
W	0042273	biological_process	ribosomal large subunit biogenesis
W	0045930	biological_process	negative regulation of mitotic cell cycle
W	0048705	biological_process	skeletal system morphogenesis
W	0061484	biological_process	hematopoietic stem cell homeostasis
W	0090263	biological_process	positive regulation of canonical Wnt signaling pathway
X	0002181	biological_process	cytoplasmic translation
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005840	cellular_component	ribosome
X	0005925	cellular_component	focal adhesion
X	0006412	biological_process	translation
X	0008270	molecular_function	zinc ion binding
X	0022625	cellular_component	cytosolic large ribosomal subunit
X	0022626	cellular_component	cytosolic ribosome
X	0045202	cellular_component	synapse
X	0046872	molecular_function	metal ion binding
X	0070062	cellular_component	extracellular exosome
X	1990904	cellular_component	ribonucleoprotein complex
Y	0002181	biological_process	cytoplasmic translation
Y	0003723	molecular_function	RNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005515	molecular_function	protein binding
Y	0005634	cellular_component	nucleus
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0015934	cellular_component	large ribosomal subunit
Y	0022625	cellular_component	cytosolic large ribosomal subunit
Y	0022626	cellular_component	cytosolic ribosome
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0002181	biological_process	cytoplasmic translation
Z	0003723	molecular_function	RNA binding
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005730	cellular_component	nucleolus
Z	0005737	cellular_component	cytoplasm
Z	0005783	cellular_component	endoplasmic reticulum
Z	0005791	cellular_component	rough endoplasmic reticulum
Z	0005829	cellular_component	cytosol
Z	0005840	cellular_component	ribosome
Z	0005925	cellular_component	focal adhesion
Z	0006412	biological_process	translation
Z	0016020	cellular_component	membrane
Z	0022625	cellular_component	cytosolic large ribosomal subunit
Z	0022626	cellular_component	cytosolic ribosome
Z	1990904	cellular_component	ribonucleoprotein complex
a	0002181	biological_process	cytoplasmic translation
a	0003723	molecular_function	RNA binding
a	0003735	molecular_function	structural constituent of ribosome
a	0005515	molecular_function	protein binding
a	0005730	cellular_component	nucleolus
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0005840	cellular_component	ribosome
a	0005925	cellular_component	focal adhesion
a	0006412	biological_process	translation
a	0016020	cellular_component	membrane
a	0022625	cellular_component	cytosolic large ribosomal subunit
a	0022626	cellular_component	cytosolic ribosome
a	0045202	cellular_component	synapse
a	1990904	cellular_component	ribonucleoprotein complex
b	0002181	biological_process	cytoplasmic translation
b	0003723	molecular_function	RNA binding
b	0003735	molecular_function	structural constituent of ribosome
b	0005515	molecular_function	protein binding
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
b	0014069	cellular_component	postsynaptic density
b	0016020	cellular_component	membrane
b	0022625	cellular_component	cytosolic large ribosomal subunit
b	0022626	cellular_component	cytosolic ribosome
b	1990904	cellular_component	ribonucleoprotein complex
c	0001649	biological_process	osteoblast differentiation
c	0003723	molecular_function	RNA binding
c	0003730	molecular_function	mRNA 3'-UTR binding
c	0005515	molecular_function	protein binding
c	0005694	cellular_component	chromosome
c	0005730	cellular_component	nucleolus
c	0005829	cellular_component	cytosol
c	0005929	cellular_component	cilium
c	0016020	cellular_component	membrane
c	0032880	biological_process	regulation of protein localization
c	0042981	biological_process	regulation of apoptotic process
c	0045296	molecular_function	cadherin binding
c	0048027	molecular_function	mRNA 5'-UTR binding
c	2000772	biological_process	regulation of cellular senescence
d	0002181	biological_process	cytoplasmic translation
d	0003723	molecular_function	RNA binding
d	0003735	molecular_function	structural constituent of ribosome
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0005840	cellular_component	ribosome
d	0005925	cellular_component	focal adhesion
d	0006412	biological_process	translation
d	0008201	molecular_function	heparin binding
d	0022625	cellular_component	cytosolic large ribosomal subunit
d	0022626	cellular_component	cytosolic ribosome
d	0042802	molecular_function	identical protein binding
d	0045202	cellular_component	synapse
d	0046632	biological_process	alpha-beta T cell differentiation
d	0070062	cellular_component	extracellular exosome
d	0098793	cellular_component	presynapse
d	0098978	cellular_component	glutamatergic synapse
d	0140236	biological_process	translation at presynapse
d	1990904	cellular_component	ribonucleoprotein complex
e	0000122	biological_process	negative regulation of transcription by RNA polymerase II
e	0001223	molecular_function	transcription coactivator binding
e	0002181	biological_process	cytoplasmic translation
e	0003723	molecular_function	RNA binding
e	0003735	molecular_function	structural constituent of ribosome
e	0005515	molecular_function	protein binding
e	0005654	cellular_component	nucleoplasm
e	0005730	cellular_component	nucleolus
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0005840	cellular_component	ribosome
e	0005925	cellular_component	focal adhesion
e	0006412	biological_process	translation
e	0006610	biological_process	ribosomal protein import into nucleus
e	0008284	biological_process	positive regulation of cell population proliferation
e	0015934	cellular_component	large ribosomal subunit
e	0016020	cellular_component	membrane
e	0022625	cellular_component	cytosolic large ribosomal subunit
e	0022626	cellular_component	cytosolic ribosome
e	0031625	molecular_function	ubiquitin protein ligase binding
e	0032986	biological_process	protein-DNA complex disassembly
e	0032991	cellular_component	protein-containing complex
e	0045202	cellular_component	synapse
e	0050821	biological_process	protein stabilization
e	0070062	cellular_component	extracellular exosome
e	0070180	molecular_function	large ribosomal subunit rRNA binding
e	0070314	biological_process	G1 to G0 transition
e	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
e	1903450	biological_process	regulation of G1 to G0 transition
e	1990904	cellular_component	ribonucleoprotein complex
e	1990948	molecular_function	ubiquitin ligase inhibitor activity
e	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
f	0000027	biological_process	ribosomal large subunit assembly
f	0000122	biological_process	negative regulation of transcription by RNA polymerase II
f	0001650	cellular_component	fibrillar center
f	0001932	biological_process	regulation of protein phosphorylation
f	0002039	molecular_function	p53 binding
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005654	cellular_component	nucleoplasm
f	0005730	cellular_component	nucleolus
f	0005829	cellular_component	cytosol
f	0006281	biological_process	DNA repair
f	0006364	biological_process	rRNA processing
f	0006974	biological_process	DNA damage response
f	0007095	biological_process	mitotic G2 DNA damage checkpoint signaling
f	0008097	molecular_function	5S rRNA binding
f	0031333	biological_process	negative regulation of protein-containing complex assembly
f	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
f	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
f	0033553	cellular_component	rDNA heterochromatin
f	0039535	biological_process	regulation of RIG-I signaling pathway
f	0042254	biological_process	ribosome biogenesis
f	0042802	molecular_function	identical protein binding
f	0042981	biological_process	regulation of apoptotic process
f	0050821	biological_process	protein stabilization
f	0051726	biological_process	regulation of cell cycle
f	0051898	biological_process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
f	0071456	biological_process	cellular response to hypoxia
f	1901796	biological_process	regulation of signal transduction by p53 class mediator
f	1901797	biological_process	negative regulation of signal transduction by p53 class mediator
f	1901837	biological_process	negative regulation of transcription of nucleolar large rRNA by RNA polymerase I
f	1902570	biological_process	protein localization to nucleolus
f	1903006	biological_process	positive regulation of protein K63-linked deubiquitination
f	1903715	biological_process	regulation of aerobic respiration
f	1990173	biological_process	protein localization to nucleoplasm
g	0002181	biological_process	cytoplasmic translation
g	0003723	molecular_function	RNA binding
g	0003735	molecular_function	structural constituent of ribosome
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005730	cellular_component	nucleolus
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
g	0019843	molecular_function	rRNA binding
g	0022625	cellular_component	cytosolic large ribosomal subunit
g	0022626	cellular_component	cytosolic ribosome
g	0045296	molecular_function	cadherin binding
g	0070062	cellular_component	extracellular exosome
g	1904841	molecular_function	TORC2 complex binding
g	1990904	cellular_component	ribonucleoprotein complex
h	0002181	biological_process	cytoplasmic translation
h	0003723	molecular_function	RNA binding
h	0003735	molecular_function	structural constituent of ribosome
h	0005515	molecular_function	protein binding
h	0005654	cellular_component	nucleoplasm
h	0005730	cellular_component	nucleolus
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0005840	cellular_component	ribosome
h	0006364	biological_process	rRNA processing
h	0006412	biological_process	translation
h	0015934	cellular_component	large ribosomal subunit
h	0016020	cellular_component	membrane
h	0022625	cellular_component	cytosolic large ribosomal subunit
h	0022626	cellular_component	cytosolic ribosome
h	0030330	biological_process	DNA damage response, signal transduction by p53 class mediator
h	0034644	biological_process	cellular response to UV
h	0042273	biological_process	ribosomal large subunit biogenesis
h	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
h	0045727	biological_process	positive regulation of translation
h	0048027	molecular_function	mRNA 5'-UTR binding
h	0070062	cellular_component	extracellular exosome
h	0071480	biological_process	cellular response to gamma radiation
h	1902167	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
h	1904803	biological_process	regulation of translation involved in cellular response to UV
h	1990904	cellular_component	ribonucleoprotein complex
i	0002181	biological_process	cytoplasmic translation
i	0003723	molecular_function	RNA binding
i	0003735	molecular_function	structural constituent of ribosome
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0005730	cellular_component	nucleolus
i	0005737	cellular_component	cytoplasm
i	0005791	cellular_component	rough endoplasmic reticulum
i	0005829	cellular_component	cytosol
i	0005840	cellular_component	ribosome
i	0005925	cellular_component	focal adhesion
i	0006364	biological_process	rRNA processing
i	0006412	biological_process	translation
i	0016020	cellular_component	membrane
i	0022625	cellular_component	cytosolic large ribosomal subunit
i	0022626	cellular_component	cytosolic ribosome
i	0045202	cellular_component	synapse
i	0070062	cellular_component	extracellular exosome
i	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
i	1990904	cellular_component	ribonucleoprotein complex
j	0002181	biological_process	cytoplasmic translation
j	0003723	molecular_function	RNA binding
j	0003735	molecular_function	structural constituent of ribosome
j	0005515	molecular_function	protein binding
j	0005654	cellular_component	nucleoplasm
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0005840	cellular_component	ribosome
j	0005925	cellular_component	focal adhesion
j	0006412	biological_process	translation
j	0015934	cellular_component	large ribosomal subunit
j	0016020	cellular_component	membrane
j	0022625	cellular_component	cytosolic large ribosomal subunit
j	0022626	cellular_component	cytosolic ribosome
j	0045202	cellular_component	synapse
j	0070062	cellular_component	extracellular exosome
j	1990904	cellular_component	ribonucleoprotein complex
k	0002181	biological_process	cytoplasmic translation
k	0003723	molecular_function	RNA binding
k	0003735	molecular_function	structural constituent of ribosome
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
k	0016020	cellular_component	membrane
k	0022625	cellular_component	cytosolic large ribosomal subunit
k	0022626	cellular_component	cytosolic ribosome
k	1990904	cellular_component	ribonucleoprotein complex
l	0002181	biological_process	cytoplasmic translation
l	0003723	molecular_function	RNA binding
l	0003735	molecular_function	structural constituent of ribosome
l	0005515	molecular_function	protein binding
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0005840	cellular_component	ribosome
l	0006412	biological_process	translation
l	0016020	cellular_component	membrane
l	0022625	cellular_component	cytosolic large ribosomal subunit
l	0022626	cellular_component	cytosolic ribosome
l	0030425	cellular_component	dendrite
l	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
l	0044297	cellular_component	cell body
l	0045202	cellular_component	synapse
l	0070062	cellular_component	extracellular exosome
l	1990904	cellular_component	ribonucleoprotein complex
m	0002181	biological_process	cytoplasmic translation
m	0003723	molecular_function	RNA binding
m	0003735	molecular_function	structural constituent of ribosome
m	0005515	molecular_function	protein binding
m	0005654	cellular_component	nucleoplasm
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0005840	cellular_component	ribosome
m	0005925	cellular_component	focal adhesion
m	0006412	biological_process	translation
m	0014069	cellular_component	postsynaptic density
m	0015934	cellular_component	large ribosomal subunit
m	0016020	cellular_component	membrane
m	0019843	molecular_function	rRNA binding
m	0022625	cellular_component	cytosolic large ribosomal subunit
m	0022626	cellular_component	cytosolic ribosome
m	0045202	cellular_component	synapse
m	0098794	cellular_component	postsynapse
m	1990904	cellular_component	ribonucleoprotein complex
n	0000049	molecular_function	tRNA binding
n	0002181	biological_process	cytoplasmic translation
n	0003723	molecular_function	RNA binding
n	0003735	molecular_function	structural constituent of ribosome
n	0005515	molecular_function	protein binding
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0005840	cellular_component	ribosome
n	0006364	biological_process	rRNA processing
n	0006412	biological_process	translation
n	0016020	cellular_component	membrane
n	0022625	cellular_component	cytosolic large ribosomal subunit
n	0022626	cellular_component	cytosolic ribosome
n	0042273	biological_process	ribosomal large subunit biogenesis
n	0045202	cellular_component	synapse
n	0070062	cellular_component	extracellular exosome
n	1990904	cellular_component	ribonucleoprotein complex
o	0002181	biological_process	cytoplasmic translation
o	0003677	molecular_function	DNA binding
o	0003723	molecular_function	RNA binding
o	0003735	molecular_function	structural constituent of ribosome
o	0005515	molecular_function	protein binding
o	0005634	cellular_component	nucleus
o	0005737	cellular_component	cytoplasm
o	0005791	cellular_component	rough endoplasmic reticulum
o	0005829	cellular_component	cytosol
o	0005840	cellular_component	ribosome
o	0005925	cellular_component	focal adhesion
o	0006355	biological_process	regulation of DNA-templated transcription
o	0006412	biological_process	translation
o	0014069	cellular_component	postsynaptic density
o	0015934	cellular_component	large ribosomal subunit
o	0016020	cellular_component	membrane
o	0022625	cellular_component	cytosolic large ribosomal subunit
o	0022626	cellular_component	cytosolic ribosome
o	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
o	0045202	cellular_component	synapse
o	0045296	molecular_function	cadherin binding
o	1990904	cellular_component	ribonucleoprotein complex
p	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
p	0002181	biological_process	cytoplasmic translation
p	0003677	molecular_function	DNA binding
p	0003723	molecular_function	RNA binding
p	0003729	molecular_function	mRNA binding
p	0003735	molecular_function	structural constituent of ribosome
p	0005515	molecular_function	protein binding
p	0005634	cellular_component	nucleus
p	0005730	cellular_component	nucleolus
p	0005737	cellular_component	cytoplasm
p	0005783	cellular_component	endoplasmic reticulum
p	0005829	cellular_component	cytosol
p	0005840	cellular_component	ribosome
p	0005925	cellular_component	focal adhesion
p	0006364	biological_process	rRNA processing
p	0006412	biological_process	translation
p	0014069	cellular_component	postsynaptic density
p	0016020	cellular_component	membrane
p	0022625	cellular_component	cytosolic large ribosomal subunit
p	0022626	cellular_component	cytosolic ribosome
p	0042273	biological_process	ribosomal large subunit biogenesis
p	0042802	molecular_function	identical protein binding
p	1990904	cellular_component	ribonucleoprotein complex
q	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
q	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
q	0003723	molecular_function	RNA binding
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005654	cellular_component	nucleoplasm
q	0005694	cellular_component	chromosome
q	0005730	cellular_component	nucleolus
q	0005829	cellular_component	cytosol
q	0006364	biological_process	rRNA processing
q	0008283	biological_process	cell population proliferation
q	0016020	cellular_component	membrane
q	0030687	cellular_component	preribosome, large subunit precursor
q	0042254	biological_process	ribosome biogenesis
q	0042273	biological_process	ribosomal large subunit biogenesis
q	0043021	molecular_function	ribonucleoprotein complex binding
q	0051726	biological_process	regulation of cell cycle
q	0070545	cellular_component	PeBoW complex
r	0003723	molecular_function	RNA binding
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005654	cellular_component	nucleoplasm
r	0005694	cellular_component	chromosome
r	0005730	cellular_component	nucleolus
r	0007059	biological_process	chromosome segregation
r	0140014	biological_process	mitotic nuclear division
t	0000794	cellular_component	condensed nuclear chromosome
t	0003676	molecular_function	nucleic acid binding
t	0003723	molecular_function	RNA binding
t	0005515	molecular_function	protein binding
t	0005654	cellular_component	nucleoplasm
t	0005694	cellular_component	chromosome
t	0005730	cellular_component	nucleolus
t	0005737	cellular_component	cytoplasm
t	0009303	biological_process	rRNA transcription
t	0016072	biological_process	rRNA metabolic process
t	0065003	biological_process	protein-containing complex assembly
u	0000166	molecular_function	nucleotide binding
u	0003723	molecular_function	RNA binding
u	0005515	molecular_function	protein binding
u	0005525	molecular_function	GTP binding
u	0005615	cellular_component	extracellular space
u	0005634	cellular_component	nucleus
u	0005654	cellular_component	nucleoplasm
u	0005694	cellular_component	chromosome
u	0005730	cellular_component	nucleolus
u	0016020	cellular_component	membrane
u	0016604	cellular_component	nuclear body
u	0017145	biological_process	stem cell division
u	0019827	biological_process	stem cell population maintenance
u	0030496	cellular_component	midbody
u	0032206	biological_process	positive regulation of telomere maintenance
u	0033235	biological_process	positive regulation of protein sumoylation
u	0042127	biological_process	regulation of cell population proliferation
u	0048027	molecular_function	mRNA 5'-UTR binding
u	1902895	biological_process	positive regulation of miRNA transcription
u	1904816	biological_process	positive regulation of protein localization to chromosome, telomeric region
v	0000027	biological_process	ribosomal large subunit assembly
v	0000956	biological_process	nuclear-transcribed mRNA catabolic process
v	0003723	molecular_function	RNA binding
v	0005515	molecular_function	protein binding
v	0005730	cellular_component	nucleolus
v	0005737	cellular_component	cytoplasm
v	0006364	biological_process	rRNA processing
v	0030687	cellular_component	preribosome, large subunit precursor
v	0042254	biological_process	ribosome biogenesis
v	0042273	biological_process	ribosomal large subunit biogenesis
w	0000166	molecular_function	nucleotide binding
w	0003723	molecular_function	RNA binding
w	0003924	molecular_function	GTPase activity
w	0005525	molecular_function	GTP binding
w	0005634	cellular_component	nucleus
w	0005730	cellular_component	nucleolus
w	0016020	cellular_component	membrane
w	0042254	biological_process	ribosome biogenesis
y	0002181	biological_process	cytoplasmic translation
y	0003723	molecular_function	RNA binding
y	0003735	molecular_function	structural constituent of ribosome
y	0005515	molecular_function	protein binding
y	0005737	cellular_component	cytoplasm
y	0005829	cellular_component	cytosol
y	0005840	cellular_component	ribosome
y	0005925	cellular_component	focal adhesion
y	0006412	biological_process	translation
y	0014069	cellular_component	postsynaptic density
y	0016020	cellular_component	membrane
y	0022625	cellular_component	cytosolic large ribosomal subunit
y	0022626	cellular_component	cytosolic ribosome
y	0070062	cellular_component	extracellular exosome
y	0070180	molecular_function	large ribosomal subunit rRNA binding
y	1990904	cellular_component	ribonucleoprotein complex
z	0001099	molecular_function	basal RNA polymerase II transcription machinery binding
z	0003723	molecular_function	RNA binding
z	0005515	molecular_function	protein binding
z	0005694	cellular_component	chromosome
z	0005730	cellular_component	nucleolus
z	0060999	biological_process	positive regulation of dendritic spine development
z	0097484	biological_process	dendrite extension

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cla..CaryFidstnlktHfrskdH

Chain	Residue	Details
9	CYS63-HIS85

---

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVIrqrksyrrk.DGvflyFedNagVI

Chain	Residue	Details
e	ALA79-ILE105

---

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLApdydaldV

Chain	Residue	Details
g	LYS134-VAL149

---

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. KTgnkIryNskrRHWRR

Chain	Residue	Details
P	LYS30-ARG46

---

site_id	PS00071
Number of Residues	8
Details	GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. SSCTTRkM

Chain	Residue	Details
1	SER3-MET10

---

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLTGQtpVfSkARyT

Chain	Residue	Details
C	LEU40-THR56

---

site_id	PS00359
Number of Residues	16
Details	RIBOSOMAL_L11 Ribosomal protein L11 signature. KeIlGTaqSVGcNVdG

Chain	Residue	Details
y	LYS130-GLY145

---

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsspCHIEMiL

Chain	Residue	Details
Y	ARG126-LEU150

---

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PrvRGVAmNPvE

Chain	Residue	Details
m	PRO197-GLU208

---

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FgqdemiDviGvTkGKGykGvtsR

Chain	Residue	Details
B	PHE211-ARG234

---

site_id	PS00475
Number of Residues	32
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGkGkLpkqp.ViVkakfFSrrAeekIksvG

Chain	Residue	Details
L	LYS110-GLY141

---

site_id	PS00526
Number of Residues	20
Details	RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaSsvlrCGkkkVWLDP

Chain	Residue	Details
a	GLN7-PRO26

---

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. KLSKIRvVRKSIARV

Chain	Residue	Details
H	LYS43-VAL57

---

site_id	PS00580
Number of Residues	21
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FiRhqsdRyvKIkrn..WRKprG

Chain	Residue	Details
k	PHE20-GLY40

---

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. VLqlLrLrQifNgTfvklnkasinMLriVepYI

Chain	Residue	Details
p	VAL108-ILE140
1	THR115-VAL147

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LASGsgDtTVRFWDL

Chain	Residue	Details
W	LEU129-LEU143
W	VAL219-THR233
W	VAL387-GLY401
W	LEU429-VAL443

---

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GESSGKNV

Chain	Residue	Details
D	GLY15-VAL22

---

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QattVknKdiRkFlDGIYVseK

Chain	Residue	Details
I	GLN163-LYS184

---

site_id	PS00709
Number of Residues	25
Details	RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkyvlGyKqtLKmiRqGkaKlVIL

Chain	Residue	Details
E	SER24-LEU48

---

site_id	PS00783
Number of Residues	24
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMLPhktkrGQaaldrLkVFdG

Chain	Residue	Details
V	VAL84-GLY107

---

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NttqKryAIcSALaASAlpalvmsKGH

Chain	Residue	Details
D	ASN116-HIS142

---

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTacGKyyrvctLaIiDpG

Chain	Residue	Details
E	GLU80-GLY100

---

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FcSgpIyPGhGmmFvRnD

Chain	Residue	Details
7	PHE8-ASP25

---

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSfGkRrnkt.HtlCrRCG

Chain	Residue	Details
M	GLY4-GLY23

---

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmgVPYciIkGKarLG

Chain	Residue	Details
G	CYS174-GLY191

---

site_id	PS01104
Number of Residues	15
Details	RIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFSLeELrvaG

Chain	Residue	Details
Q	ARG71-GLY85

---

site_id	PS01105
Number of Residues	22
Details	RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRaHGnsGmVrAkFrsnLP

Chain	Residue	Details
n	GLY72-PRO93

---

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLfmSRtnRPpLSLsRM

Chain	Residue	Details
Z	LYS49-MET66

---

site_id	PS01107
Number of Residues	12
Details	RIBOSOMAL_L27E Ribosomal protein L27e signature. GKNkWFFqkLRF

Chain	Residue	Details
i	GLY125-PHE136

---

site_id	PS01108
Number of Residues	19
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVqVVrGhyKGqqiGkV

Chain	Residue	Details
h	ASP52-VAL70

---

site_id	PS01144
Number of Residues	15
Details	RIBOSOMAL_L31E Ribosomal protein L31e signature. VRIDtrLNkAvWaKG

Chain	Residue	Details
j	VAL62-GLY76

---

site_id	PS01145
Number of Residues	14
Details	RIBOSOMAL_L34E Ribosomal protein L34e signature. TaSnKtrlsRTPGN

Chain	Residue	Details
F	THR15-ASN28

---

site_id	PS01170
Number of Residues	19
Details	RIBOSOMAL_L6E Ribosomal protein L6e signature. NrvPLRRthqkFVIATSt.K

Chain	Residue	Details
o	ASN182-LYS200

---

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikgmgtvqk.GmpHkcYhGkTG

Chain	Residue	Details
T	GLY37-GLY62

---

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRaMELLK

Chain	Residue	Details
K	PRO52-LYS62

---

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVIYRiRVrRG

Chain	Residue	Details
U	ASP46-GLY69

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"O55135","evidenceCode":"ECO:0000250"},{"source":"HAMAP-Rule","id":"MF_03132","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O55135","evidenceCode":"ECO:0000250"},{"source":"HAMAP-Rule","id":"MF_03132","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by CK1","evidences":[{"source":"HAMAP-Rule","id":"MF_03132","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12917340","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21084295","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by PKC","evidences":[{"source":"HAMAP-Rule","id":"MF_03132","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"14654845","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	24
Details	Zinc finger: {"description":"C2H2-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	91
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	142
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P27659","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	Modified residue: {"description":"Tele-methylhistidine","evidences":[{"source":"PubMed","id":"33693809","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35674491","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P27659","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	8
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	49
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25772364","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	12
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	27
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	1
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"UniProtKB","id":"Q9D8E6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9D8E6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P50878","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	1
Details	Modified residue: {"description":"Citrulline","evidences":[{"source":"UniProtKB","id":"Q9D8E6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	9
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	146
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	7
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00768","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	18
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P49166","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q9CR57","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P61314","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	1
Details	Lipidation: {"description":"N-myristoyl glycine","evidences":[{"source":"PubMed","id":"25255805","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	2
Details	Modified residue: {"description":"Citrulline","evidences":[{"source":"UniProtKB","id":"P19253","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by ZIPK/DAPK3","evidences":[{"source":"PubMed","id":"18995835","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	21
Details	Zinc finger: {"description":"C4-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	3
Details	Modified residue: {"description":"Citrulline","evidences":[{"source":"UniProtKB","id":"P84099","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62717","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P62717","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI52
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI53
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"12962325","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"DEC-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Boldt K.","von Kriegsheim A.","Lilla S.","Lempens A.","Kolch W."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI54
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI55
Number of Residues	1
Details	Modified residue: {"description":"(3S)-3-hydroxyhistidine","evidences":[{"source":"PubMed","id":"23103944","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI56
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"O55142","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI57
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P47911","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI58
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17924679","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI59
Number of Residues	11
Details	Repeat: {"description":"3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI60
Number of Residues	11
Details	Repeat: {"description":"4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI61
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P14148","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI62
Number of Residues	161
Details	Domain: {"description":"CP-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01058","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI63
Number of Residues	11
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI64
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI65
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI66
Number of Residues	3
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"36638793","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI67
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI68
Number of Residues	1
Details	Modified residue: {"description":"N-acetylglycine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI69
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P47962","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI70
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI71
Number of Residues	39
Details	Repeat: {"description":"WD 1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI72
Number of Residues	39
Details	Repeat: {"description":"WD 2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI73
Number of Residues	44
Details	Repeat: {"description":"WD 3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI74
Number of Residues	38
Details	Repeat: {"description":"WD 4","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI75
Number of Residues	41
Details	Repeat: {"description":"WD 5","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI76
Number of Residues	39
Details	Repeat: {"description":"WD 6","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI77
Number of Residues	39
Details	Repeat: {"description":"WD 7","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI78
Number of Residues	31
Details	Repeat: {"description":"WD 8","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI79
Number of Residues	171
Details	Domain: {"description":"OBG-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01047","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI80
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01047","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI81
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"OCT-2004","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V."]}}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI82
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI83
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI84
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62911","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI85
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P62900","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI86
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62900","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI87
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62900","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI88
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI89
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P67984","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI90
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P67984","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI91
Number of Residues	78
Details	Domain: {"description":"RRM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI92
Number of Residues	1
Details	Modified residue: {"description":"Omega-N-methylarginine; by PRMT1 and PRMT8","evidences":[{"source":"PubMed","id":"26529540","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI93
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9D8M4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI94
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI95
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9D1R9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI96
Number of Residues	35
Details	Domain: {"description":"KOW"}

Chain

Residue

Details

---

site_id	SWS_FT_FI97
Number of Residues	93
Details	Domain: {"description":"BRCT","evidences":[{"source":"HAMAP-Rule","id":"MF_03028","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI98
Number of Residues	53
Details	Region: {"description":"Required for 28S ribosomal RNA processing"}

Chain

Residue

Details

---

site_id	SWS_FT_FI99
Number of Residues	109
Details	Region: {"description":"Sufficient for interaction with MAP1B","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI100
Number of Residues	42
Details	Region: {"description":"Beta-like import receptor binding (BIB) domain","evidences":[{"source":"PubMed","id":"9687515","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI101
Number of Residues	1
Details	Modified residue: {"description":"Citrulline","evidences":[{"source":"UniProtKB","id":"P62751","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI102
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI103
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P62751","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI104
Number of Residues	44
Details	Region: {"description":"Mediates interaction with human herpesvirus 8 protein ORF16","evidences":[{"source":"PubMed","id":"20042497","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI105
Number of Residues	130
Details	Region: {"description":"Nucleolar localization signal","evidences":[{"source":"PubMed","id":"22292050","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---