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8HUQ

X-ray structure of human PPAR alpha ligand binding domain-elafibranor-SRC1 coactivator peptide co-crystals obtained by soaking

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000269|PubMed:19116277, ECO:0007744|PDB:3ET1
ChainResidueDetails
ASER280
ATYR314
ATYR464

site_idSWS_FT_FI2
Number of Residues1
DetailsSITE: Essential for heterodimerization with RXRA
ChainResidueDetails
ALEU433

221716

PDB entries from 2024-06-26

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