8HUB

AMP deaminase 2 in complex with an inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003876	molecular_function	AMP deaminase activity
A	0009168	biological_process	purine ribonucleoside monophosphate biosynthetic process
A	0019239	molecular_function	deaminase activity
A	0032264	biological_process	IMP salvage
B	0003876	molecular_function	AMP deaminase activity
B	0009168	biological_process	purine ribonucleoside monophosphate biosynthetic process
B	0019239	molecular_function	deaminase activity
B	0032264	biological_process	IMP salvage
C	0003876	molecular_function	AMP deaminase activity
C	0009168	biological_process	purine ribonucleoside monophosphate biosynthetic process
C	0019239	molecular_function	deaminase activity
C	0032264	biological_process	IMP salvage
D	0003876	molecular_function	AMP deaminase activity
D	0009168	biological_process	purine ribonucleoside monophosphate biosynthetic process
D	0019239	molecular_function	deaminase activity
D	0032264	biological_process	IMP salvage

Functional Information from PROSITE/UniProt

site_id	PS00485
Number of Residues	7
Details	A_DEAMINASE Adenosine and AMP deaminase signature. SLSTDDP

Chain	Residue	Details
A	SER760-PRO766

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10104

Chain	Residue	Details
A	PRO655
B	PRO655
C	PRO655
D	PRO655

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site_id	SWS_FT_FI2
Number of Residues	28
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ALA364
B	LYS435
B	PRO633
B	HIS636
B	GLY710
B	LEU711
C	ALA364
C	ILE366
C	LYS435
C	PRO633
C	HIS636
A	ILE366
C	GLY710
C	LEU711
D	ALA364
D	ILE366
D	LYS435
D	PRO633
D	HIS636
D	GLY710
D	LEU711
A	LYS435
A	PRO633
A	HIS636
A	GLY710
A	LEU711
B	ALA364
B	ILE366

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