8HPC

Crystal structure of C171A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-Hydroxyphenylglycine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003837	molecular_function	beta-ureidopropionase activity
A	0006807	biological_process	obsolete nitrogen compound metabolic process
A	0016787	molecular_function	hydrolase activity
A	0033396	biological_process	beta-alanine biosynthetic process via 3-ureidopropionate
A	0047417	molecular_function	N-carbamoyl-D-amino acid hydrolase activity
B	0003837	molecular_function	beta-ureidopropionase activity
B	0006807	biological_process	obsolete nitrogen compound metabolic process
B	0016787	molecular_function	hydrolase activity
B	0033396	biological_process	beta-alanine biosynthetic process via 3-ureidopropionate
B	0047417	molecular_function	N-carbamoyl-D-amino acid hydrolase activity
C	0003837	molecular_function	beta-ureidopropionase activity
C	0006807	biological_process	obsolete nitrogen compound metabolic process
C	0016787	molecular_function	hydrolase activity
C	0033396	biological_process	beta-alanine biosynthetic process via 3-ureidopropionate
C	0047417	molecular_function	N-carbamoyl-D-amino acid hydrolase activity
D	0003837	molecular_function	beta-ureidopropionase activity
D	0006807	biological_process	obsolete nitrogen compound metabolic process
D	0016787	molecular_function	hydrolase activity
D	0033396	biological_process	beta-alanine biosynthetic process via 3-ureidopropionate
D	0047417	molecular_function	N-carbamoyl-D-amino acid hydrolase activity
E	0003837	molecular_function	beta-ureidopropionase activity
E	0006807	biological_process	obsolete nitrogen compound metabolic process
E	0016787	molecular_function	hydrolase activity
E	0033396	biological_process	beta-alanine biosynthetic process via 3-ureidopropionate
E	0047417	molecular_function	N-carbamoyl-D-amino acid hydrolase activity
F	0003837	molecular_function	beta-ureidopropionase activity
F	0006807	biological_process	obsolete nitrogen compound metabolic process
F	0016787	molecular_function	hydrolase activity
F	0033396	biological_process	beta-alanine biosynthetic process via 3-ureidopropionate
F	0047417	molecular_function	N-carbamoyl-D-amino acid hydrolase activity
G	0003837	molecular_function	beta-ureidopropionase activity
G	0006807	biological_process	obsolete nitrogen compound metabolic process
G	0016787	molecular_function	hydrolase activity
G	0033396	biological_process	beta-alanine biosynthetic process via 3-ureidopropionate
G	0047417	molecular_function	N-carbamoyl-D-amino acid hydrolase activity
H	0003837	molecular_function	beta-ureidopropionase activity
H	0006807	biological_process	obsolete nitrogen compound metabolic process
H	0016787	molecular_function	hydrolase activity
H	0033396	biological_process	beta-alanine biosynthetic process via 3-ureidopropionate
H	0047417	molecular_function	N-carbamoyl-D-amino acid hydrolase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	ACT_SITE:

Chain	Residue	Details
A	GLU67
D	GLU67
D	LYS147
D	ALA192
E	GLU67
E	LYS147
E	ALA192
F	GLU67
F	LYS147
F	ALA192
G	GLU67
A	LYS147
G	LYS147
G	ALA192
H	GLU67
H	LYS147
H	ALA192
A	ALA192
B	GLU67
B	LYS147
B	ALA192
C	GLU67
C	LYS147
C	ALA192

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	3
Details	M-CSA 674

Chain	Residue	Details
A	GLU67	proton shuttle (general acid/base)
A	LYS147	electrostatic stabiliser
A	ALA192	covalent catalysis, proton shuttle (general acid/base)

---

site_id	MCSA2
Number of Residues	3
Details	M-CSA 674

Chain	Residue	Details
B	GLU67	proton shuttle (general acid/base)
B	LYS147	electrostatic stabiliser
B	ALA192	covalent catalysis, proton shuttle (general acid/base)

---

site_id	MCSA3
Number of Residues	3
Details	M-CSA 674

Chain	Residue	Details
C	GLU67	proton shuttle (general acid/base)
C	LYS147	electrostatic stabiliser
C	ALA192	covalent catalysis, proton shuttle (general acid/base)

---

site_id	MCSA4
Number of Residues	3
Details	M-CSA 674

Chain	Residue	Details
D	GLU67	proton shuttle (general acid/base)
D	LYS147	electrostatic stabiliser
D	ALA192	covalent catalysis, proton shuttle (general acid/base)

---

site_id	MCSA5
Number of Residues	3
Details	M-CSA 674

Chain	Residue	Details
E	GLU67	proton shuttle (general acid/base)
E	LYS147	electrostatic stabiliser
E	ALA192	covalent catalysis, proton shuttle (general acid/base)

---

site_id	MCSA6
Number of Residues	3
Details	M-CSA 674

Chain	Residue	Details
F	GLU67	proton shuttle (general acid/base)
F	LYS147	electrostatic stabiliser
F	ALA192	covalent catalysis, proton shuttle (general acid/base)

---

site_id	MCSA7
Number of Residues	3
Details	M-CSA 674

Chain	Residue	Details
G	GLU67	proton shuttle (general acid/base)
G	LYS147	electrostatic stabiliser
G	ALA192	covalent catalysis, proton shuttle (general acid/base)

---

site_id	MCSA8
Number of Residues	3
Details	M-CSA 674

Chain	Residue	Details
H	GLU67	proton shuttle (general acid/base)
H	LYS147	electrostatic stabiliser
H	ALA192	covalent catalysis, proton shuttle (general acid/base)

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