8HL6

Crystal structure of human valosin-containing protein methyltransferase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006338	biological_process	chromatin remodeling
A	0008168	molecular_function	methyltransferase activity
A	0008276	molecular_function	protein methyltransferase activity
A	0016279	molecular_function	protein-lysine N-methyltransferase activity
A	0018022	biological_process	peptidyl-lysine methylation
A	0018023	biological_process	peptidyl-lysine trimethylation
A	0032259	biological_process	methylation
A	0032780	biological_process	negative regulation of ATP-dependent activity
A	0032991	cellular_component	protein-containing complex
A	0042054	molecular_function	histone methyltransferase activity
A	0051117	molecular_function	ATPase binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|Ref.9

Chain	Residue	Details
A	TRP43
A	GLY75
A	ASP96
A	TRP126
A	ALA143
A	TYR148

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylalanine => ECO:0007744|PubMed:22814378

Chain	Residue	Details
A	ALA2

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER8

---