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8HFR

NPC-trapped pre-60S particle

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
AN0000049molecular_functiontRNA binding
AN0000055biological_processribosomal large subunit export from nucleus
AN0000056biological_processribosomal small subunit export from nucleus
AN0003723molecular_functionRNA binding
AN0003729molecular_functionmRNA binding
AN0005515molecular_functionprotein binding
AN0005634cellular_componentnucleus
AN0005643cellular_componentnuclear pore
AN0005737cellular_componentcytoplasm
AN0006406biological_processmRNA export from nucleus
AN0006409biological_processtRNA export from nucleus
AN0008033biological_processtRNA processing
AN0015288molecular_functionporin activity
AN0016973biological_processpoly(A)+ mRNA export from nucleus
AN0017070molecular_functionU6 snRNA binding
AN0030619molecular_functionU1 snRNA binding
AN0030620molecular_functionU2 snRNA binding
AN0030621molecular_functionU4 snRNA binding
AN0030623molecular_functionU5 snRNA binding
AN0042272cellular_componentnuclear RNA export factor complex
AN0051028biological_processmRNA transport
AN0055085biological_processtransmembrane transport
AN0071528biological_processtRNA re-export from nucleus
As0000055biological_processribosomal large subunit export from nucleus
As0002181biological_processcytoplasmic translation
As0003723molecular_functionRNA binding
As0003735molecular_functionstructural constituent of ribosome
As0005737cellular_componentcytoplasm
As0005829cellular_componentcytosol
As0005840cellular_componentribosome
As0006412biological_processtranslation
As0015934cellular_componentlarge ribosomal subunit
As0022625cellular_componentcytosolic large ribosomal subunit
As0042254biological_processribosome biogenesis
As1990904cellular_componentribonucleoprotein complex
aw0002181biological_processcytoplasmic translation
aw0003723molecular_functionRNA binding
aw0003735molecular_functionstructural constituent of ribosome
aw0005634cellular_componentnucleus
aw0005737cellular_componentcytoplasm
aw0005829cellular_componentcytosol
aw0005840cellular_componentribosome
aw0006412biological_processtranslation
aw0015934cellular_componentlarge ribosomal subunit
aw0022625cellular_componentcytosolic large ribosomal subunit
aw0043232cellular_componentintracellular non-membrane-bounded organelle
aw1990904cellular_componentribonucleoprotein complex
b30002181biological_processcytoplasmic translation
b30003735molecular_functionstructural constituent of ribosome
b30005737cellular_componentcytoplasm
b30005829cellular_componentcytosol
b30005840cellular_componentribosome
b30006412biological_processtranslation
b30022625cellular_componentcytosolic large ribosomal subunit
b31990904cellular_componentribonucleoprotein complex
B40002181biological_processcytoplasmic translation
B40003723molecular_functionRNA binding
B40003735molecular_functionstructural constituent of ribosome
B40005737cellular_componentcytoplasm
B40005829cellular_componentcytosol
B40005840cellular_componentribosome
B40006412biological_processtranslation
B40019843molecular_functionrRNA binding
B40022625cellular_componentcytosolic large ribosomal subunit
B40022626cellular_componentcytosolic ribosome
B40042273biological_processribosomal large subunit biogenesis
B41990145biological_processmaintenance of translational fidelity
B41990904cellular_componentribonucleoprotein complex
Bt0000055biological_processribosomal large subunit export from nucleus
Bt0000056biological_processribosomal small subunit export from nucleus
Bt0005515molecular_functionprotein binding
Bt0005634cellular_componentnucleus
Bt0006406biological_processmRNA export from nucleus
Bt0006409biological_processtRNA export from nucleus
Bt0006913biological_processnucleocytoplasmic transport
Bt0008033biological_processtRNA processing
Bt0016973biological_processpoly(A)+ mRNA export from nucleus
Bt0042272cellular_componentnuclear RNA export factor complex
Bt0044613cellular_componentnuclear pore central transport channel
cC0002181biological_processcytoplasmic translation
cC0003723molecular_functionRNA binding
cC0003735molecular_functionstructural constituent of ribosome
cC0005737cellular_componentcytoplasm
cC0005829cellular_componentcytosol
cC0005840cellular_componentribosome
cC0006364biological_processrRNA processing
cC0022625cellular_componentcytosolic large ribosomal subunit
cC0030627molecular_functionpre-mRNA 5'-splice site binding
cC0048025biological_processnegative regulation of mRNA splicing, via spliceosome
cC1990904cellular_componentribonucleoprotein complex
CD0000027biological_processribosomal large subunit assembly
CD0002181biological_processcytoplasmic translation
CD0003723molecular_functionRNA binding
CD0003735molecular_functionstructural constituent of ribosome
CD0005515molecular_functionprotein binding
CD0005737cellular_componentcytoplasm
CD0005829cellular_componentcytosol
CD0005840cellular_componentribosome
CD0006364biological_processrRNA processing
CD0006412biological_processtranslation
CD0006414biological_processtranslational elongation
CD0022625cellular_componentcytosolic large ribosomal subunit
CD1990145biological_processmaintenance of translational fidelity
CD1990904cellular_componentribonucleoprotein complex
CW0000049molecular_functiontRNA binding
CW0000055biological_processribosomal large subunit export from nucleus
CW0000056biological_processribosomal small subunit export from nucleus
CW0003723molecular_functionRNA binding
CW0003729molecular_functionmRNA binding
CW0005515molecular_functionprotein binding
CW0005634cellular_componentnucleus
CW0005643cellular_componentnuclear pore
CW0005737cellular_componentcytoplasm
CW0006406biological_processmRNA export from nucleus
CW0006409biological_processtRNA export from nucleus
CW0008033biological_processtRNA processing
CW0015288molecular_functionporin activity
CW0016973biological_processpoly(A)+ mRNA export from nucleus
CW0017070molecular_functionU6 snRNA binding
CW0030619molecular_functionU1 snRNA binding
CW0030620molecular_functionU2 snRNA binding
CW0030621molecular_functionU4 snRNA binding
CW0030623molecular_functionU5 snRNA binding
CW0042272cellular_componentnuclear RNA export factor complex
CW0051028biological_processmRNA transport
CW0055085biological_processtransmembrane transport
CW0071528biological_processtRNA re-export from nucleus
dG0002181biological_processcytoplasmic translation
dG0003735molecular_functionstructural constituent of ribosome
dG0005737cellular_componentcytoplasm
dG0005829cellular_componentcytosol
dG0005840cellular_componentribosome
dG0006412biological_processtranslation
dG0006450biological_processregulation of translational fidelity
dG0022625cellular_componentcytosolic large ribosomal subunit
dG1990904cellular_componentribonucleoprotein complex
DK0000055biological_processribosomal large subunit export from nucleus
DK0000056biological_processribosomal small subunit export from nucleus
DK0005515molecular_functionprotein binding
DK0005634cellular_componentnucleus
DK0006406biological_processmRNA export from nucleus
DK0006409biological_processtRNA export from nucleus
DK0006913biological_processnucleocytoplasmic transport
DK0008033biological_processtRNA processing
DK0016973biological_processpoly(A)+ mRNA export from nucleus
DK0042272cellular_componentnuclear RNA export factor complex
DK0044613cellular_componentnuclear pore central transport channel
DO0002181biological_processcytoplasmic translation
DO0003723molecular_functionRNA binding
DO0003735molecular_functionstructural constituent of ribosome
DO0005634cellular_componentnucleus
DO0005737cellular_componentcytoplasm
DO0005829cellular_componentcytosol
DO0005840cellular_componentribosome
DO0006412biological_processtranslation
DO0022625cellular_componentcytosolic large ribosomal subunit
DO1990904cellular_componentribonucleoprotein complex
eH0002181biological_processcytoplasmic translation
eH0003735molecular_functionstructural constituent of ribosome
eH0005737cellular_componentcytoplasm
eH0005829cellular_componentcytosol
eH0005840cellular_componentribosome
eH0006412biological_processtranslation
eH0022625cellular_componentcytosolic large ribosomal subunit
eH1990904cellular_componentribonucleoprotein complex
EX0000049molecular_functiontRNA binding
EX0000055biological_processribosomal large subunit export from nucleus
EX0000056biological_processribosomal small subunit export from nucleus
EX0003723molecular_functionRNA binding
EX0003729molecular_functionmRNA binding
EX0005515molecular_functionprotein binding
EX0005634cellular_componentnucleus
EX0005643cellular_componentnuclear pore
EX0005737cellular_componentcytoplasm
EX0006406biological_processmRNA export from nucleus
EX0006409biological_processtRNA export from nucleus
EX0008033biological_processtRNA processing
EX0015288molecular_functionporin activity
EX0016973biological_processpoly(A)+ mRNA export from nucleus
EX0017070molecular_functionU6 snRNA binding
EX0030619molecular_functionU1 snRNA binding
EX0030620molecular_functionU2 snRNA binding
EX0030621molecular_functionU4 snRNA binding
EX0030623molecular_functionU5 snRNA binding
EX0042272cellular_componentnuclear RNA export factor complex
EX0051028biological_processmRNA transport
EX0055085biological_processtransmembrane transport
EX0071528biological_processtRNA re-export from nucleus
Ez0000027biological_processribosomal large subunit assembly
Ez0002181biological_processcytoplasmic translation
Ez0003735molecular_functionstructural constituent of ribosome
Ez0005515molecular_functionprotein binding
Ez0005634cellular_componentnucleus
Ez0005737cellular_componentcytoplasm
Ez0005829cellular_componentcytosol
Ez0005840cellular_componentribosome
Ez0006412biological_processtranslation
Ez0008097molecular_function5S rRNA binding
Ez0019843molecular_functionrRNA binding
Ez0022625cellular_componentcytosolic large ribosomal subunit
Ez1990904cellular_componentribonucleoprotein complex
f70000027biological_processribosomal large subunit assembly
f70002181biological_processcytoplasmic translation
f70003735molecular_functionstructural constituent of ribosome
f70005737cellular_componentcytoplasm
f70005829cellular_componentcytosol
f70005840cellular_componentribosome
f70006364biological_processrRNA processing
f70006412biological_processtranslation
f70022625cellular_componentcytosolic large ribosomal subunit
f70042273biological_processribosomal large subunit biogenesis
f71990904cellular_componentribonucleoprotein complex
F80000027biological_processribosomal large subunit assembly
F80002181biological_processcytoplasmic translation
F80003723molecular_functionRNA binding
F80003735molecular_functionstructural constituent of ribosome
F80005737cellular_componentcytoplasm
F80005829cellular_componentcytosol
F80005840cellular_componentribosome
F80006412biological_processtranslation
F80022625cellular_componentcytosolic large ribosomal subunit
F81990904cellular_componentribonucleoprotein complex
FR0000055biological_processribosomal large subunit export from nucleus
FR0000056biological_processribosomal small subunit export from nucleus
FR0005515molecular_functionprotein binding
FR0005634cellular_componentnucleus
FR0006406biological_processmRNA export from nucleus
FR0006409biological_processtRNA export from nucleus
FR0006913biological_processnucleocytoplasmic transport
FR0008033biological_processtRNA processing
FR0016973biological_processpoly(A)+ mRNA export from nucleus
FR0042272cellular_componentnuclear RNA export factor complex
FR0044613cellular_componentnuclear pore central transport channel
g20002181biological_processcytoplasmic translation
g20003735molecular_functionstructural constituent of ribosome
g20005737cellular_componentcytoplasm
g20005829cellular_componentcytosol
g20005840cellular_componentribosome
g20006412biological_processtranslation
g20022625cellular_componentcytosolic large ribosomal subunit
g20030687cellular_componentpreribosome, large subunit precursor
g20042254biological_processribosome biogenesis
g21990904cellular_componentribonucleoprotein complex
Gu0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Gu0000470biological_processmaturation of LSU-rRNA
Gu0002181biological_processcytoplasmic translation
Gu0003723molecular_functionRNA binding
Gu0003735molecular_functionstructural constituent of ribosome
Gu0005737cellular_componentcytoplasm
Gu0005829cellular_componentcytosol
Gu0005840cellular_componentribosome
Gu0022625cellular_componentcytosolic large ribosomal subunit
Gu0042273biological_processribosomal large subunit biogenesis
Gu1990904cellular_componentribonucleoprotein complex
h10000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
h10002181biological_processcytoplasmic translation
h10003729molecular_functionmRNA binding
h10003735molecular_functionstructural constituent of ribosome
h10005737cellular_componentcytoplasm
h10005829cellular_componentcytosol
h10005840cellular_componentribosome
h10006412biological_processtranslation
h10022625cellular_componentcytosolic large ribosomal subunit
h10030687cellular_componentpreribosome, large subunit precursor
h11990904cellular_componentribonucleoprotein complex
Hj0000470biological_processmaturation of LSU-rRNA
Hj0002181biological_processcytoplasmic translation
Hj0003723molecular_functionRNA binding
Hj0003735molecular_functionstructural constituent of ribosome
Hj0005737cellular_componentcytoplasm
Hj0005829cellular_componentcytosol
Hj0005840cellular_componentribosome
Hj0022625cellular_componentcytosolic large ribosomal subunit
Hj0042254biological_processribosome biogenesis
Hj1990904cellular_componentribonucleoprotein complex
ia0002181biological_processcytoplasmic translation
ia0003723molecular_functionRNA binding
ia0003735molecular_functionstructural constituent of ribosome
ia0005737cellular_componentcytoplasm
ia0005829cellular_componentcytosol
ia0005840cellular_componentribosome
ia0006412biological_processtranslation
ia0022625cellular_componentcytosolic large ribosomal subunit
ia1990904cellular_componentribonucleoprotein complex
Ib0002181biological_processcytoplasmic translation
Ib0003735molecular_functionstructural constituent of ribosome
Ib0005737cellular_componentcytoplasm
Ib0005829cellular_componentcytosol
Ib0005840cellular_componentribosome
Ib0006412biological_processtranslation
Ib0019843molecular_functionrRNA binding
Ib0022625cellular_componentcytosolic large ribosomal subunit
Ib1990904cellular_componentribonucleoprotein complex
jh0000448biological_processcleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
jh0002181biological_processcytoplasmic translation
jh0003723molecular_functionRNA binding
jh0003735molecular_functionstructural constituent of ribosome
jh0005737cellular_componentcytoplasm
jh0005829cellular_componentcytosol
jh0005840cellular_componentribosome
jh0006412biological_processtranslation
jh0008270molecular_functionzinc ion binding
jh0019843molecular_functionrRNA binding
jh0022625cellular_componentcytosolic large ribosomal subunit
jh0030687cellular_componentpreribosome, large subunit precursor
jh0044391cellular_componentribosomal subunit
jh0046872molecular_functionmetal ion binding
jh1990904cellular_componentribonucleoprotein complex
Jy0000027biological_processribosomal large subunit assembly
Jy0002181biological_processcytoplasmic translation
Jy0003723molecular_functionRNA binding
Jy0003735molecular_functionstructural constituent of ribosome
Jy0005634cellular_componentnucleus
Jy0005737cellular_componentcytoplasm
Jy0005829cellular_componentcytosol
Jy0005840cellular_componentribosome
Jy0006412biological_processtranslation
Jy0019843molecular_functionrRNA binding
Jy0022625cellular_componentcytosolic large ribosomal subunit
Jy1990904cellular_componentribonucleoprotein complex
KM0000027biological_processribosomal large subunit assembly
KM0002181biological_processcytoplasmic translation
KM0003723molecular_functionRNA binding
KM0003735molecular_functionstructural constituent of ribosome
KM0005737cellular_componentcytoplasm
KM0005829cellular_componentcytosol
KM0005840cellular_componentribosome
KM0006412biological_processtranslation
KM0022625cellular_componentcytosolic large ribosomal subunit
KM0070180molecular_functionlarge ribosomal subunit rRNA binding
KM1990904cellular_componentribonucleoprotein complex
kr0002181biological_processcytoplasmic translation
kr0003735molecular_functionstructural constituent of ribosome
kr0005737cellular_componentcytoplasm
kr0005829cellular_componentcytosol
kr0005840cellular_componentribosome
kr0006412biological_processtranslation
kr0022618biological_processprotein-RNA complex assembly
kr0022625cellular_componentcytosolic large ribosomal subunit
kr1990904cellular_componentribonucleoprotein complex
li0002181biological_processcytoplasmic translation
li0003735molecular_functionstructural constituent of ribosome
li0005515molecular_functionprotein binding
li0005737cellular_componentcytoplasm
li0005829cellular_componentcytosol
li0005840cellular_componentribosome
li0006412biological_processtranslation
li0022625cellular_componentcytosolic large ribosomal subunit
li1990904cellular_componentribonucleoprotein complex
LL0002181biological_processcytoplasmic translation
LL0003723molecular_functionRNA binding
LL0003735molecular_functionstructural constituent of ribosome
LL0005737cellular_componentcytoplasm
LL0005829cellular_componentcytosol
LL0005840cellular_componentribosome
LL0006412biological_processtranslation
LL0022625cellular_componentcytosolic large ribosomal subunit
LL1990904cellular_componentribonucleoprotein complex
MQ0000027biological_processribosomal large subunit assembly
MQ0000470biological_processmaturation of LSU-rRNA
MQ0002181biological_processcytoplasmic translation
MQ0003723molecular_functionRNA binding
MQ0003735molecular_functionstructural constituent of ribosome
MQ0005730cellular_componentnucleolus
MQ0005737cellular_componentcytoplasm
MQ0005829cellular_componentcytosol
MQ0005840cellular_componentribosome
MQ0006412biological_processtranslation
MQ0016236biological_processmacroautophagy
MQ0022625cellular_componentcytosolic large ribosomal subunit
MQ0032991cellular_componentprotein-containing complex
MQ0042273biological_processribosomal large subunit biogenesis
MQ0043229cellular_componentintracellular organelle
MQ1990904cellular_componentribonucleoprotein complex
mS0002181biological_processcytoplasmic translation
mS0003735molecular_functionstructural constituent of ribosome
mS0005737cellular_componentcytoplasm
mS0005829cellular_componentcytosol
mS0005840cellular_componentribosome
mS0006412biological_processtranslation
mS0008270molecular_functionzinc ion binding
mS0022625cellular_componentcytosolic large ribosomal subunit
mS0044391cellular_componentribosomal subunit
mS0046677biological_processresponse to antibiotic
mS0046898biological_processresponse to cycloheximide
mS1990904cellular_componentribonucleoprotein complex
No0002181biological_processcytoplasmic translation
No0003723molecular_functionRNA binding
No0003735molecular_functionstructural constituent of ribosome
No0005737cellular_componentcytoplasm
No0005829cellular_componentcytosol
No0005840cellular_componentribosome
No0006412biological_processtranslation
No0022625cellular_componentcytosolic large ribosomal subunit
No0022626cellular_componentcytosolic ribosome
No1990904cellular_componentribonucleoprotein complex
nY0002181biological_processcytoplasmic translation
nY0003735molecular_functionstructural constituent of ribosome
nY0005737cellular_componentcytoplasm
nY0005829cellular_componentcytosol
nY0005840cellular_componentribosome
nY0006412biological_processtranslation
nY0022625cellular_componentcytosolic large ribosomal subunit
nY0044391cellular_componentribosomal subunit
nY0046872molecular_functionmetal ion binding
nY0070180molecular_functionlarge ribosomal subunit rRNA binding
nY1990904cellular_componentribonucleoprotein complex
O60000470biological_processmaturation of LSU-rRNA
O60002181biological_processcytoplasmic translation
O60003723molecular_functionRNA binding
O60003729molecular_functionmRNA binding
O60003735molecular_functionstructural constituent of ribosome
O60005730cellular_componentnucleolus
O60005737cellular_componentcytoplasm
O60005829cellular_componentcytosol
O60005840cellular_componentribosome
O60006412biological_processtranslation
O60015934cellular_componentlarge ribosomal subunit
O60017148biological_processnegative regulation of translation
O60022625cellular_componentcytosolic large ribosomal subunit
O61990904cellular_componentribonucleoprotein complex
ox0000055biological_processribosomal large subunit export from nucleus
ox0003676molecular_functionnucleic acid binding
ox0005634cellular_componentnucleus
ox0005737cellular_componentcytoplasm
ox0008270molecular_functionzinc ion binding
ox0030687cellular_componentpreribosome, large subunit precursor
ox0042254biological_processribosome biogenesis
ox0043023molecular_functionribosomal large subunit binding
ox0046872molecular_functionmetal ion binding
pT0000055biological_processribosomal large subunit export from nucleus
pT0003674molecular_functionmolecular_function
pT0005515molecular_functionprotein binding
pT0005634cellular_componentnucleus
pT0005654cellular_componentnucleoplasm
pT0005730cellular_componentnucleolus
pT0005737cellular_componentcytoplasm
pT0006508biological_processproteolysis
pT0008237molecular_functionmetallopeptidase activity
pT0030687cellular_componentpreribosome, large subunit precursor
pT0046872molecular_functionmetal ion binding
Pv0000448biological_processcleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Pv0002181biological_processcytoplasmic translation
Pv0003735molecular_functionstructural constituent of ribosome
Pv0005737cellular_componentcytoplasm
Pv0005829cellular_componentcytosol
Pv0005840cellular_componentribosome
Pv0006412biological_processtranslation
Pv0015934cellular_componentlarge ribosomal subunit
Pv0022625cellular_componentcytosolic large ribosomal subunit
Pv0030687cellular_componentpreribosome, large subunit precursor
Pv1990904cellular_componentribonucleoprotein complex
qJ0003674molecular_functionmolecular_function
qJ0005515molecular_functionprotein binding
qJ0005634cellular_componentnucleus
qJ0005737cellular_componentcytoplasm
qJ0042254biological_processribosome biogenesis
qJ0042273biological_processribosomal large subunit biogenesis
Qk0002181biological_processcytoplasmic translation
Qk0003723molecular_functionRNA binding
Qk0003735molecular_functionstructural constituent of ribosome
Qk0005737cellular_componentcytoplasm
Qk0005829cellular_componentcytosol
Qk0005840cellular_componentribosome
Qk0006412biological_processtranslation
Qk0022625cellular_componentcytosolic large ribosomal subunit
Qk0043232cellular_componentintracellular non-membrane-bounded organelle
Qk1990904cellular_componentribonucleoprotein complex
rA0000054biological_processribosomal subunit export from nucleus
rA0003723molecular_functionRNA binding
rA0003924molecular_functionGTPase activity
rA0005515molecular_functionprotein binding
rA0005525molecular_functionGTP binding
rA0005634cellular_componentnucleus
rA0005730cellular_componentnucleolus
rA0005737cellular_componentcytoplasm
rA0006364biological_processrRNA processing
rA0030687cellular_componentpreribosome, large subunit precursor
rA0042254biological_processribosome biogenesis
rA0042273biological_processribosomal large subunit biogenesis
rA1902626biological_processassembly of large subunit precursor of preribosome
RP0002181biological_processcytoplasmic translation
RP0003723molecular_functionRNA binding
RP0003735molecular_functionstructural constituent of ribosome
RP0005737cellular_componentcytoplasm
RP0005829cellular_componentcytosol
RP0005840cellular_componentribosome
RP0006412biological_processtranslation
RP0022625cellular_componentcytosolic large ribosomal subunit
RP1990904cellular_componentribonucleoprotein complex
sm0003674molecular_functionmolecular_function
sm0005515molecular_functionprotein binding
sm0005634cellular_componentnucleus
sm0008150biological_processbiological_process
SZ0002181biological_processcytoplasmic translation
SZ0003735molecular_functionstructural constituent of ribosome
SZ0005737cellular_componentcytoplasm
SZ0005829cellular_componentcytosol
SZ0005840cellular_componentribosome
SZ0006412biological_processtranslation
SZ0022625cellular_componentcytosolic large ribosomal subunit
SZ1990904cellular_componentribonucleoprotein complex
tB0001671molecular_functionATPase activator activity
tB0005634cellular_componentnucleus
tB0005730cellular_componentnucleolus
tB0005737cellular_componentcytoplasm
tB0030687cellular_componentpreribosome, large subunit precursor
tB0032781biological_processpositive regulation of ATP-dependent activity
tB0042254biological_processribosome biogenesis
tB0042273biological_processribosomal large subunit biogenesis
tB0051117molecular_functionATPase binding
tB1902626biological_processassembly of large subunit precursor of preribosome
Tl0002181biological_processcytoplasmic translation
Tl0003735molecular_functionstructural constituent of ribosome
Tl0005737cellular_componentcytoplasm
Tl0005829cellular_componentcytosol
Tl0005840cellular_componentribosome
Tl0006412biological_processtranslation
Tl0022625cellular_componentcytosolic large ribosomal subunit
Tl1990904cellular_componentribonucleoprotein complex
UF0002181biological_processcytoplasmic translation
UF0003723molecular_functionRNA binding
UF0003735molecular_functionstructural constituent of ribosome
UF0005737cellular_componentcytoplasm
UF0005829cellular_componentcytosol
UF0005840cellular_componentribosome
UF0006412biological_processtranslation
UF0022625cellular_componentcytosolic large ribosomal subunit
UF1990904cellular_componentribonucleoprotein complex
V50002181biological_processcytoplasmic translation
V50003735molecular_functionstructural constituent of ribosome
V50005737cellular_componentcytoplasm
V50005829cellular_componentcytosol
V50005840cellular_componentribosome
V50006412biological_processtranslation
V50022625cellular_componentcytosolic large ribosomal subunit
V50070180molecular_functionlarge ribosomal subunit rRNA binding
V51990904cellular_componentribonucleoprotein complex
v90000055biological_processribosomal large subunit export from nucleus
v90003924molecular_functionGTPase activity
v90005515molecular_functionprotein binding
v90005525molecular_functionGTP binding
v90005634cellular_componentnucleus
v90005654cellular_componentnucleoplasm
v90005730cellular_componentnucleolus
v90030687cellular_componentpreribosome, large subunit precursor
v90042254biological_processribosome biogenesis
v90070180molecular_functionlarge ribosomal subunit rRNA binding
v92000200biological_processregulation of ribosomal subunit export from nucleus
vV0000055biological_processribosomal large subunit export from nucleus
vV0005515molecular_functionprotein binding
vV0005634cellular_componentnucleus
vV0005654cellular_componentnucleoplasm
vV0005737cellular_componentcytoplasm
vV0005829cellular_componentcytosol
vV0015031biological_processprotein transport
vV0030674molecular_functionprotein-macromolecule adaptor activity
vV0043023molecular_functionribosomal large subunit binding
vV0070180molecular_functionlarge ribosomal subunit rRNA binding
Wg0000027biological_processribosomal large subunit assembly
Wg0000055biological_processribosomal large subunit export from nucleus
Wg0000956biological_processnuclear-transcribed mRNA catabolic process
Wg0005634cellular_componentnucleus
Wg0005654cellular_componentnucleoplasm
Wg0005730cellular_componentnucleolus
Wg0005737cellular_componentcytoplasm
Wg0006364biological_processrRNA processing
Wg0030490biological_processmaturation of SSU-rRNA
Wg0030687cellular_componentpreribosome, large subunit precursor
Wg0032040cellular_componentsmall-subunit processome
Wg0042254biological_processribosome biogenesis
Wg0042273biological_processribosomal large subunit biogenesis
Wg0070180molecular_functionlarge ribosomal subunit rRNA binding
Xc0000027biological_processribosomal large subunit assembly
Xc0002181biological_processcytoplasmic translation
Xc0003723molecular_functionRNA binding
Xc0003735molecular_functionstructural constituent of ribosome
Xc0005515molecular_functionprotein binding
Xc0005737cellular_componentcytoplasm
Xc0005829cellular_componentcytosol
Xc0005840cellular_componentribosome
Xc0006412biological_processtranslation
Xc0019843molecular_functionrRNA binding
Xc0022625cellular_componentcytosolic large ribosomal subunit
Xc0030687cellular_componentpreribosome, large subunit precursor
Xc1990904cellular_componentribonucleoprotein complex
xd0000460biological_processmaturation of 5.8S rRNA
xd0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
xd0000466biological_processmaturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
xd0000470biological_processmaturation of LSU-rRNA
xd0003674molecular_functionmolecular_function
xd0005515molecular_functionprotein binding
xd0005634cellular_componentnucleus
xd0005730cellular_componentnucleolus
xd0006364biological_processrRNA processing
xd0030687cellular_componentpreribosome, large subunit precursor
xd0042254biological_processribosome biogenesis
xd0042273biological_processribosomal large subunit biogenesis
xI0000055biological_processribosomal large subunit export from nucleus
xI0003674molecular_functionmolecular_function
xI0005634cellular_componentnucleus
xI0005730cellular_componentnucleolus
xI0005737cellular_componentcytoplasm
xI0030687cellular_componentpreribosome, large subunit precursor
xI0042254biological_processribosome biogenesis
yE0000054biological_processribosomal subunit export from nucleus
yE0000460biological_processmaturation of 5.8S rRNA
yE0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
yE0000466biological_processmaturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
yE0000470biological_processmaturation of LSU-rRNA
yE0003743molecular_functiontranslation initiation factor activity
yE0005515molecular_functionprotein binding
yE0005634cellular_componentnucleus
yE0005730cellular_componentnucleolus
yE0005737cellular_componentcytoplasm
yE0005829cellular_componentcytosol
yE0006364biological_processrRNA processing
yE0006412biological_processtranslation
yE0006413biological_processtranslational initiation
yE0030687cellular_componentpreribosome, large subunit precursor
yE0042254biological_processribosome biogenesis
yE0042256biological_processcytosolic ribosome assembly
yE0042273biological_processribosomal large subunit biogenesis
yE0043022molecular_functionribosome binding
yE0043023molecular_functionribosomal large subunit binding
yE1902626biological_processassembly of large subunit precursor of preribosome
YU0002181biological_processcytoplasmic translation
YU0003723molecular_functionRNA binding
YU0003735molecular_functionstructural constituent of ribosome
YU0005737cellular_componentcytoplasm
YU0005829cellular_componentcytosol
YU0005840cellular_componentribosome
YU0006412biological_processtranslation
YU0015934cellular_componentlarge ribosomal subunit
YU0022625cellular_componentcytosolic large ribosomal subunit
YU0032991cellular_componentprotein-containing complex
YU0042273biological_processribosomal large subunit biogenesis
YU0043229cellular_componentintracellular organelle
YU1990904cellular_componentribonucleoprotein complex
zp0003674molecular_functionmolecular_function
zp0005634cellular_componentnucleus
zp0005730cellular_componentnucleolus
zp0008150biological_processbiological_process
zp0030687cellular_componentpreribosome, large subunit precursor
Zq0002181biological_processcytoplasmic translation
Zq0003735molecular_functionstructural constituent of ribosome
Zq0005737cellular_componentcytoplasm
Zq0005829cellular_componentcytosol
Zq0005840cellular_componentribosome
Zq0006412biological_processtranslation
Zq0022625cellular_componentcytosolic large ribosomal subunit
Zq1990904cellular_componentribonucleoprotein complex
Functional Information from PROSITE/UniProt
site_idPS00028
Number of Residues23
DetailsZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cih..CakyMetaialktHlkgkvH
ChainResidueDetails
oxCYS51-HIS73

site_idPS00049
Number of Residues27
DetailsRIBOSOMAL_L14 Ribosomal protein L14 signature. AIVVrqakswrrr.DGvflyFedNagVI
ChainResidueDetails
V5ALA76-ILE102

site_idPS00050
Number of Residues16
DetailsRIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLTadydaldI
ChainResidueDetails
XcLYS119-ILE134

site_idPS00051
Number of Residues17
DetailsRIBOSOMAL_L39E Ribosomal protein L39e signature. RTnntIryNakrRNWRR
ChainResidueDetails
liARG30-ARG46

site_idPS00358
Number of Residues17
DetailsRIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLSGQtpVqSkARyT
ChainResidueDetails
JyLEU37-THR53

site_idPS00359
Number of Residues15
DetailsRIBOSOMAL_L11 Ribosomal protein L11 signature. KeIlGTaqSVGcRV.D
ChainResidueDetails
KMLYS130-ASP144

site_idPS00464
Number of Residues25
DetailsRIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinkyesspSHIELvV
ChainResidueDetails
PvARG126-VAL150

site_idPS00467
Number of Residues12
DetailsRIBOSOMAL_L2 Ribosomal protein L2 signature. PktRGVAmNPvD
ChainResidueDetails
B4PRO197-ASP208

site_idPS00474
Number of Residues24
DetailsRIBOSOMAL_L3 Ribosomal protein L3 signature. FeqnemiDaiAvTkGHGfeGvthR
ChainResidueDetails
CDPHE209-ARG232

site_idPS00475
Number of Residues32
DetailsRIBOSOMAL_L15 Ribosomal protein L15 signature. KILGkGrIpnvp.ViVkarfVSklAeekIraaG
ChainResidueDetails
awLYS111-GLY142

site_idPS00526
Number of Residues20
DetailsRIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaAsvvgVGkrkVWLDP
ChainResidueDetails
RPGLN7-PRO26

site_idPS00579
Number of Residues15
DetailsRIBOSOMAL_L29 Ribosomal protein L29 signature. SLPKIKtVRKSIACV
ChainResidueDetails
h1SER40-VAL54

site_idPS00580
Number of Residues21
DetailsRIBOSOMAL_L32E Ribosomal protein L32e signature. FkRhhsdRyhRVaen..WRKqkG
ChainResidueDetails
eHPHE17-GLY37

site_idPS00634
Number of Residues33
DetailsRIBOSOMAL_L30 Ribosomal protein L30 signature. VLqlLrLtRinSgTfvkvtkatleLLklIepYV
ChainResidueDetails
GuVAL102-VAL134

site_idPS00700
Number of Residues22
DetailsRIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QicrVrnKdiRkFlDGIYVshK
ChainResidueDetails
IbGLN163-LYS184

site_idPS00709
Number of Residues25
DetailsRIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkytlGyKstVKslRqGksKlIII
ChainResidueDetails
cCSER20-ILE44

site_idPS00783
Number of Residues24
DetailsRIBOSOMAL_L13 Ribosomal protein L13 signature. LRGMVShktarGKaalerLkVFeG
ChainResidueDetails
O6LEU84-GLY107

site_idPS00939
Number of Residues27
DetailsRIBOSOMAL_L1E Ribosomal protein L1e signature. NhneKryATaSAIaATAvaslvlaRGH
ChainResidueDetails
DOASN114-HIS140

site_idPS00993
Number of Residues21
DetailsRIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTavGKlfrvgvVsIlEaG
ChainResidueDetails
cCGLU76-GLY96

site_idPS01077
Number of Residues20
DetailsRIBOSOMAL_L37E Ribosomal protein L37e signature. GTpSfGkRhnks.HtlCnRCG
ChainResidueDetails
jhGLY4-GLY23

site_idPS01082
Number of Residues18
DetailsRIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CkkmgVPYaiVkGKarLG
ChainResidueDetails
HjCYS170-GLY187

site_idPS01104
Number of Residues15
DetailsRIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFTLaEVkaaG
ChainResidueDetails
LLARG70-GLY84

site_idPS01105
Number of Residues22
DetailsRIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRtHGnsGvVrAtFrnnLP
ChainResidueDetails
f7GLY69-PRO90

site_idPS01106
Number of Residues18
DetailsRIBOSOMAL_L18E Ribosomal protein L18e signature. KaLflSKinRPpVSVsRI
ChainResidueDetails
QkLYS50-ILE67

site_idPS01107
Number of Residues12
DetailsRIBOSOMAL_L27E Ribosomal protein L27e signature. GKNqWFFskLRF
ChainResidueDetails
ZqGLY125-PHE136

site_idPS01108
Number of Residues18
DetailsRIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVlVVrGskKGqe.GkI
ChainResidueDetails
YUASP53-ILE70

site_idPS01144
Number of Residues15
DetailsRIBOSOMAL_L31E Ribosomal protein L31e signature. VRLApeLNqAiWkRG
ChainResidueDetails
dGVAL49-GLY63

site_idPS01145
Number of Residues14
DetailsRIBOSOMAL_L34E Ribosomal protein L34e signature. TrSnKikvvKTPGG
ChainResidueDetails
g2THR15-GLY28

site_idPS01170
Number of Residues19
DetailsRIBOSOMAL_L6E Ribosomal protein L6e signature. NgvPLRRvnarYVIATSt.K
ChainResidueDetails
F8ASN72-LYS90

site_idPS01171
Number of Residues26
DetailsRIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikangsiqk.GmpHkfYqGkTG
ChainResidueDetails
TlGLY37-GLY62

site_idPS01172
Number of Residues12
DetailsRIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKvvLRleC
ChainResidueDetails
mSLYS63-CYS74

site_idPS01190
Number of Residues11
DetailsRIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRlIDLIR
ChainResidueDetails
iaPRO52-ARG62

site_idPS01194
Number of Residues24
DetailsRIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGFVIYRvRVrRG
ChainResidueDetails
NoASP46-GLY69

site_idPS01199
Number of Residues20
DetailsRIBOSOMAL_L1 Ribosomal protein L1 signature. IkqVprlLGpqLSKAGkFPT
ChainResidueDetails
AsILE117-THR136

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198
ChainResidueDetails
EzSER167
EzSER176
RPSER91
cCLYS83

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:19779198
ChainResidueDetails
EzSER235
jhCYS22
jhCYS34
jhCYS37
RPLYS146
RPLYS186

site_idSWS_FT_FI3
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
EzLYS164
B4LYS93
B4LYS119
B4LYS145

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198
ChainResidueDetails
AsSER86

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
ChainResidueDetails
KMSER38
CDLYS136

site_idSWS_FT_FI6
Number of Residues1
DetailsMOD_RES: N5-methylarginine; by RMT2 => ECO:0000269|PubMed:11856739, ECO:0000269|PubMed:18957409
ChainResidueDetails
KMARG67

site_idSWS_FT_FI7
Number of Residues3
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
KMLYS130
KMLYS146

222926

PDB entries from 2024-07-24

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