8HFC

Cryo-EM structure of yeast Erf2/Erf4 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005794	cellular_component	Golgi apparatus
A	0006612	biological_process	protein targeting to membrane
A	0008270	molecular_function	zinc ion binding
A	0016020	cellular_component	membrane
A	0016409	molecular_function	palmitoyltransferase activity
A	0016746	molecular_function	acyltransferase activity
A	0018345	biological_process	protein palmitoylation
A	0019706	molecular_function	protein-cysteine S-palmitoyltransferase activity
A	0031211	cellular_component	endoplasmic reticulum palmitoyltransferase complex
A	0032541	cellular_component	cortical endoplasmic reticulum
A	0097038	cellular_component	perinuclear endoplasmic reticulum
B	0005515	molecular_function	protein binding
B	0005783	cellular_component	endoplasmic reticulum
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0006612	biological_process	protein targeting to membrane
B	0016020	cellular_component	membrane
B	0016409	molecular_function	palmitoyltransferase activity
B	0031211	cellular_component	endoplasmic reticulum palmitoyltransferase complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	252
Details	TOPO_DOM: Cytoplasmic => ECO:0000255

Chain	Residue	Details
A	MET1-PRO75
A	ARG126-PHE217
A	THR272-ILE359

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site_id	SWS_FT_FI2
Number of Residues	80
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	LEU76-ALA96
A	GLY105-ILE125
A	PHE218-ILE238
A	PRO251-PHE271

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site_id	SWS_FT_FI3
Number of Residues	18
Details	TOPO_DOM: Lumenal => ECO:0000255

Chain	Residue	Details
A	HIS97-ASN104
A	HIS239-CYS250

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site_id	SWS_FT_FI4
Number of Residues	1
Details	ACT_SITE: S-palmitoyl cysteine intermediate => ECO:0000250|UniProtKB:Q8VDZ4

Chain	Residue	Details
A	CYS203

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