8GZU

Cryo-EM structure of Tetrahymena thermophila respiratory Megacomplex MC (IV2+I+III2+II)2

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
03	0005743	cellular_component	mitochondrial inner membrane
03	0016020	cellular_component	membrane
07	0005743	cellular_component	mitochondrial inner membrane
07	0016020	cellular_component	membrane
0C	0005737	cellular_component	cytoplasm
0C	0005739	cellular_component	mitochondrion
0C	0043231	cellular_component	intracellular membrane-bounded organelle
0C	0046872	molecular_function	metal ion binding
0C	0051536	molecular_function	iron-sulfur cluster binding
0C	0051537	molecular_function	2 iron, 2 sulfur cluster binding
0F	0046872	molecular_function	metal ion binding
12	0046872	molecular_function	metal ion binding
1b	0016020	cellular_component	membrane
1B	0016020	cellular_component	membrane
1t	0005743	cellular_component	mitochondrial inner membrane
1t	0015031	biological_process	protein transport
1T	0005743	cellular_component	mitochondrial inner membrane
1T	0015031	biological_process	protein transport
24	0000166	molecular_function	nucleotide binding
24	0005524	molecular_function	ATP binding
26	0004129	molecular_function	cytochrome-c oxidase activity
26	0005743	cellular_component	mitochondrial inner membrane
26	0006119	biological_process	oxidative phosphorylation
26	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
26	0009060	biological_process	aerobic respiration
26	0015990	biological_process	electron transport coupled proton transport
26	0016020	cellular_component	membrane
26	0016491	molecular_function	oxidoreductase activity
26	0020037	molecular_function	heme binding
26	0022904	biological_process	respiratory electron transport chain
26	0046872	molecular_function	metal ion binding
27	0004129	molecular_function	cytochrome-c oxidase activity
27	0005507	molecular_function	copper ion binding
27	0016020	cellular_component	membrane
27	0016491	molecular_function	oxidoreductase activity
27	0042773	biological_process	ATP synthesis coupled electron transport
27	0046872	molecular_function	metal ion binding
27	1902600	biological_process	proton transmembrane transport
29	0005740	cellular_component	mitochondrial envelope
29	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
29	0045277	cellular_component	respiratory chain complex IV
29	0046872	molecular_function	metal ion binding
2b	0016491	molecular_function	oxidoreductase activity
2B	0016491	molecular_function	oxidoreductase activity
2e	0046872	molecular_function	metal ion binding
2E	0046872	molecular_function	metal ion binding
31	0000166	molecular_function	nucleotide binding
31	0005524	molecular_function	ATP binding
36	0003700	molecular_function	DNA-binding transcription factor activity
36	0005634	cellular_component	nucleus
36	0006355	biological_process	regulation of DNA-templated transcription
37	0016020	cellular_component	membrane
38	0016020	cellular_component	membrane
39	0016020	cellular_component	membrane
40	0005743	cellular_component	mitochondrial inner membrane
40	0015031	biological_process	protein transport
47	0005737	cellular_component	cytoplasm
47	0005739	cellular_component	mitochondrion
47	0043231	cellular_component	intracellular membrane-bounded organelle
47	0046872	molecular_function	metal ion binding
47	0051536	molecular_function	iron-sulfur cluster binding
47	0051537	molecular_function	2 iron, 2 sulfur cluster binding
50	0046872	molecular_function	metal ion binding
58	0005743	cellular_component	mitochondrial inner membrane
58	0016020	cellular_component	membrane
62	0005743	cellular_component	mitochondrial inner membrane
62	0016020	cellular_component	membrane
67	0046872	molecular_function	metal ion binding
6b	0000166	molecular_function	nucleotide binding
6b	0005524	molecular_function	ATP binding
6B	0000166	molecular_function	nucleotide binding
6B	0005524	molecular_function	ATP binding
79	0000166	molecular_function	nucleotide binding
79	0005524	molecular_function	ATP binding
7l	0003700	molecular_function	DNA-binding transcription factor activity
7l	0005634	cellular_component	nucleus
7l	0006355	biological_process	regulation of DNA-templated transcription
7L	0003700	molecular_function	DNA-binding transcription factor activity
7L	0005634	cellular_component	nucleus
7L	0006355	biological_process	regulation of DNA-templated transcription
81	0004129	molecular_function	cytochrome-c oxidase activity
81	0005743	cellular_component	mitochondrial inner membrane
81	0006119	biological_process	oxidative phosphorylation
81	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
81	0009060	biological_process	aerobic respiration
81	0015990	biological_process	electron transport coupled proton transport
81	0016020	cellular_component	membrane
81	0016491	molecular_function	oxidoreductase activity
81	0020037	molecular_function	heme binding
81	0022904	biological_process	respiratory electron transport chain
81	0046872	molecular_function	metal ion binding
82	0004129	molecular_function	cytochrome-c oxidase activity
82	0005507	molecular_function	copper ion binding
82	0016020	cellular_component	membrane
82	0016491	molecular_function	oxidoreductase activity
82	0042773	biological_process	ATP synthesis coupled electron transport
82	0046872	molecular_function	metal ion binding
82	1902600	biological_process	proton transmembrane transport
84	0005740	cellular_component	mitochondrial envelope
84	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
84	0045277	cellular_component	respiratory chain complex IV
84	0046872	molecular_function	metal ion binding
86	0000166	molecular_function	nucleotide binding
86	0005524	molecular_function	ATP binding
91	0003700	molecular_function	DNA-binding transcription factor activity
91	0005634	cellular_component	nucleus
91	0006355	biological_process	regulation of DNA-templated transcription
92	0016020	cellular_component	membrane
93	0016020	cellular_component	membrane
94	0016020	cellular_component	membrane
95	0005743	cellular_component	mitochondrial inner membrane
95	0015031	biological_process	protein transport
a2	0005743	cellular_component	mitochondrial inner membrane
a2	0005840	cellular_component	ribosome
a2	0022904	biological_process	respiratory electron transport chain
A2	0005743	cellular_component	mitochondrial inner membrane
A2	0005840	cellular_component	ribosome
A2	0022904	biological_process	respiratory electron transport chain
a5	0005743	cellular_component	mitochondrial inner membrane
a5	0022904	biological_process	respiratory electron transport chain
A5	0005743	cellular_component	mitochondrial inner membrane
A5	0022904	biological_process	respiratory electron transport chain
a6	0005743	cellular_component	mitochondrial inner membrane
a6	0006979	biological_process	response to oxidative stress
a6	0022904	biological_process	respiratory electron transport chain
A6	0005743	cellular_component	mitochondrial inner membrane
A6	0006979	biological_process	response to oxidative stress
A6	0022904	biological_process	respiratory electron transport chain
a7	0000166	molecular_function	nucleotide binding
A7	0000166	molecular_function	nucleotide binding
a9	0000166	molecular_function	nucleotide binding
a9	0005739	cellular_component	mitochondrion
a9	0044877	molecular_function	protein-containing complex binding
a9	0046872	molecular_function	metal ion binding
A9	0000166	molecular_function	nucleotide binding
A9	0005739	cellular_component	mitochondrion
A9	0044877	molecular_function	protein-containing complex binding
A9	0046872	molecular_function	metal ion binding
ab	0000035	molecular_function	acyl binding
ab	0000036	molecular_function	acyl carrier activity
ab	0005739	cellular_component	mitochondrion
ab	0006629	biological_process	lipid metabolic process
ab	0006631	biological_process	fatty acid metabolic process
ab	0006633	biological_process	fatty acid biosynthetic process
AB	0000035	molecular_function	acyl binding
AB	0000036	molecular_function	acyl carrier activity
AB	0005739	cellular_component	mitochondrion
AB	0006629	biological_process	lipid metabolic process
AB	0006631	biological_process	fatty acid metabolic process
AB	0006633	biological_process	fatty acid biosynthetic process
ac	0000035	molecular_function	acyl binding
ac	0000036	molecular_function	acyl carrier activity
ac	0005739	cellular_component	mitochondrion
ac	0006629	biological_process	lipid metabolic process
ac	0006631	biological_process	fatty acid metabolic process
ac	0006633	biological_process	fatty acid biosynthetic process
AC	0000035	molecular_function	acyl binding
AC	0000036	molecular_function	acyl carrier activity
AC	0005739	cellular_component	mitochondrion
AC	0006629	biological_process	lipid metabolic process
AC	0006631	biological_process	fatty acid metabolic process
AC	0006633	biological_process	fatty acid biosynthetic process
al	0005743	cellular_component	mitochondrial inner membrane
al	0006979	biological_process	response to oxidative stress
al	0016020	cellular_component	membrane
al	0022904	biological_process	respiratory electron transport chain
al	0045271	cellular_component	respiratory chain complex I
AL	0005743	cellular_component	mitochondrial inner membrane
AL	0006979	biological_process	response to oxidative stress
AL	0016020	cellular_component	membrane
AL	0022904	biological_process	respiratory electron transport chain
AL	0045271	cellular_component	respiratory chain complex I
an	0046872	molecular_function	metal ion binding
AN	0046872	molecular_function	metal ion binding
b8	0000166	molecular_function	nucleotide binding
B8	0000166	molecular_function	nucleotide binding
b9	0000166	molecular_function	nucleotide binding
B9	0000166	molecular_function	nucleotide binding
c1	0004129	molecular_function	cytochrome-c oxidase activity
c1	0005743	cellular_component	mitochondrial inner membrane
c1	0006119	biological_process	oxidative phosphorylation
c1	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
c1	0009060	biological_process	aerobic respiration
c1	0015990	biological_process	electron transport coupled proton transport
c1	0016020	cellular_component	membrane
c1	0016491	molecular_function	oxidoreductase activity
c1	0020037	molecular_function	heme binding
c1	0022904	biological_process	respiratory electron transport chain
c1	0046872	molecular_function	metal ion binding
C1	0004129	molecular_function	cytochrome-c oxidase activity
C1	0005743	cellular_component	mitochondrial inner membrane
C1	0006119	biological_process	oxidative phosphorylation
C1	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
C1	0009060	biological_process	aerobic respiration
C1	0015990	biological_process	electron transport coupled proton transport
C1	0016020	cellular_component	membrane
C1	0016491	molecular_function	oxidoreductase activity
C1	0020037	molecular_function	heme binding
C1	0022904	biological_process	respiratory electron transport chain
C1	0046872	molecular_function	metal ion binding
c2	0004129	molecular_function	cytochrome-c oxidase activity
c2	0005507	molecular_function	copper ion binding
c2	0016020	cellular_component	membrane
c2	0016491	molecular_function	oxidoreductase activity
c2	0042773	biological_process	ATP synthesis coupled electron transport
c2	0046872	molecular_function	metal ion binding
c2	1902600	biological_process	proton transmembrane transport
C2	0004129	molecular_function	cytochrome-c oxidase activity
C2	0005507	molecular_function	copper ion binding
C2	0016020	cellular_component	membrane
C2	0016491	molecular_function	oxidoreductase activity
C2	0042773	biological_process	ATP synthesis coupled electron transport
C2	0046872	molecular_function	metal ion binding
C2	1902600	biological_process	proton transmembrane transport
d	0005743	cellular_component	mitochondrial inner membrane
d	0016020	cellular_component	membrane
D	0005743	cellular_component	mitochondrial inner membrane
D	0016020	cellular_component	membrane
fs	0005737	cellular_component	cytoplasm
fs	0005739	cellular_component	mitochondrion
fs	0043231	cellular_component	intracellular membrane-bounded organelle
fs	0046872	molecular_function	metal ion binding
fs	0051536	molecular_function	iron-sulfur cluster binding
fs	0051537	molecular_function	2 iron, 2 sulfur cluster binding
FS	0005737	cellular_component	cytoplasm
FS	0005739	cellular_component	mitochondrion
FS	0043231	cellular_component	intracellular membrane-bounded organelle
FS	0046872	molecular_function	metal ion binding
FS	0051536	molecular_function	iron-sulfur cluster binding
FS	0051537	molecular_function	2 iron, 2 sulfur cluster binding
fx	0005739	cellular_component	mitochondrion
fx	0009055	molecular_function	electron transfer activity
fx	0022900	biological_process	electron transport chain
fx	0046872	molecular_function	metal ion binding
fx	0051536	molecular_function	iron-sulfur cluster binding
fx	0051537	molecular_function	2 iron, 2 sulfur cluster binding
fx	0140647	biological_process	P450-containing electron transport chain
FX	0005739	cellular_component	mitochondrion
FX	0009055	molecular_function	electron transfer activity
FX	0022900	biological_process	electron transport chain
FX	0046872	molecular_function	metal ion binding
FX	0051536	molecular_function	iron-sulfur cluster binding
FX	0051537	molecular_function	2 iron, 2 sulfur cluster binding
FX	0140647	biological_process	P450-containing electron transport chain
h	0005743	cellular_component	mitochondrial inner membrane
h	0016020	cellular_component	membrane
H	0005743	cellular_component	mitochondrial inner membrane
H	0016020	cellular_component	membrane
j1	0005737	cellular_component	cytoplasm
j1	0006457	biological_process	protein folding
j1	0044183	molecular_function	protein folding chaperone
j1	0051082	molecular_function	unfolded protein binding
j1	0051087	molecular_function	protein-folding chaperone binding
J1	0005737	cellular_component	cytoplasm
J1	0006457	biological_process	protein folding
J1	0044183	molecular_function	protein folding chaperone
J1	0051082	molecular_function	unfolded protein binding
J1	0051087	molecular_function	protein-folding chaperone binding
m	0046872	molecular_function	metal ion binding
M	0046872	molecular_function	metal ion binding
m1	0016020	cellular_component	membrane
M1	0016020	cellular_component	membrane
m2	0016020	cellular_component	membrane
M2	0016020	cellular_component	membrane
m3	0016020	cellular_component	membrane
M3	0016020	cellular_component	membrane
n1	0003954	molecular_function	NADH dehydrogenase activity
n1	0005743	cellular_component	mitochondrial inner membrane
n1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
n1	0009060	biological_process	aerobic respiration
n1	0016020	cellular_component	membrane
n1	0016491	molecular_function	oxidoreductase activity
n1	1902600	biological_process	proton transmembrane transport
N1	0003954	molecular_function	NADH dehydrogenase activity
N1	0005743	cellular_component	mitochondrial inner membrane
N1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N1	0009060	biological_process	aerobic respiration
N1	0016020	cellular_component	membrane
N1	0016491	molecular_function	oxidoreductase activity
N1	1902600	biological_process	proton transmembrane transport
n3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
n3	0016020	cellular_component	membrane
n3	0016491	molecular_function	oxidoreductase activity
n3	0022904	biological_process	respiratory electron transport chain
n3	0030964	cellular_component	NADH dehydrogenase complex
n3	0031966	cellular_component	mitochondrial membrane
n3	1902600	biological_process	proton transmembrane transport
N3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N3	0016020	cellular_component	membrane
N3	0016491	molecular_function	oxidoreductase activity
N3	0022904	biological_process	respiratory electron transport chain
N3	0030964	cellular_component	NADH dehydrogenase complex
N3	0031966	cellular_component	mitochondrial membrane
N3	1902600	biological_process	proton transmembrane transport
n4	0005886	cellular_component	plasma membrane
n4	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
n4	0016491	molecular_function	oxidoreductase activity
n4	0022904	biological_process	respiratory electron transport chain
n4	0031966	cellular_component	mitochondrial membrane
n4	0042773	biological_process	ATP synthesis coupled electron transport
n4	1902600	biological_process	proton transmembrane transport
N4	0005886	cellular_component	plasma membrane
N4	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N4	0016491	molecular_function	oxidoreductase activity
N4	0022904	biological_process	respiratory electron transport chain
N4	0031966	cellular_component	mitochondrial membrane
N4	0042773	biological_process	ATP synthesis coupled electron transport
N4	1902600	biological_process	proton transmembrane transport
n5	0003954	molecular_function	NADH dehydrogenase activity
n5	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
n5	0015990	biological_process	electron transport coupled proton transport
n5	0016020	cellular_component	membrane
n5	0016491	molecular_function	oxidoreductase activity
n5	0042773	biological_process	ATP synthesis coupled electron transport
N5	0003954	molecular_function	NADH dehydrogenase activity
N5	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N5	0015990	biological_process	electron transport coupled proton transport
N5	0016020	cellular_component	membrane
N5	0016491	molecular_function	oxidoreductase activity
N5	0042773	biological_process	ATP synthesis coupled electron transport
qa	0005739	cellular_component	mitochondrion
qa	0046872	molecular_function	metal ion binding
qA	0005739	cellular_component	mitochondrion
qA	0046872	molecular_function	metal ion binding
Qa	0005739	cellular_component	mitochondrion
Qa	0046872	molecular_function	metal ion binding
QA	0005739	cellular_component	mitochondrion
QA	0046872	molecular_function	metal ion binding
qb	0005739	cellular_component	mitochondrion
qb	0006508	biological_process	proteolysis
qb	0008233	molecular_function	peptidase activity
qb	0008237	molecular_function	metallopeptidase activity
qb	0016787	molecular_function	hydrolase activity
qb	0046872	molecular_function	metal ion binding
qB	0005739	cellular_component	mitochondrion
qB	0006508	biological_process	proteolysis
qB	0008233	molecular_function	peptidase activity
qB	0008237	molecular_function	metallopeptidase activity
qB	0016787	molecular_function	hydrolase activity
qB	0046872	molecular_function	metal ion binding
Qb	0005739	cellular_component	mitochondrion
Qb	0006508	biological_process	proteolysis
Qb	0008233	molecular_function	peptidase activity
Qb	0008237	molecular_function	metallopeptidase activity
Qb	0016787	molecular_function	hydrolase activity
Qb	0046872	molecular_function	metal ion binding
QB	0005739	cellular_component	mitochondrion
QB	0006508	biological_process	proteolysis
QB	0008233	molecular_function	peptidase activity
QB	0008237	molecular_function	metallopeptidase activity
QB	0016787	molecular_function	hydrolase activity
QB	0046872	molecular_function	metal ion binding
qc	0009055	molecular_function	electron transfer activity
qc	0016020	cellular_component	membrane
qc	0016491	molecular_function	oxidoreductase activity
qc	0022904	biological_process	respiratory electron transport chain
qc	0046872	molecular_function	metal ion binding
qC	0009055	molecular_function	electron transfer activity
qC	0016020	cellular_component	membrane
qC	0016491	molecular_function	oxidoreductase activity
qC	0022904	biological_process	respiratory electron transport chain
qC	0046872	molecular_function	metal ion binding
Qc	0009055	molecular_function	electron transfer activity
Qc	0016020	cellular_component	membrane
Qc	0016491	molecular_function	oxidoreductase activity
Qc	0022904	biological_process	respiratory electron transport chain
Qc	0046872	molecular_function	metal ion binding
QC	0009055	molecular_function	electron transfer activity
QC	0016020	cellular_component	membrane
QC	0016491	molecular_function	oxidoreductase activity
QC	0022904	biological_process	respiratory electron transport chain
QC	0046872	molecular_function	metal ion binding
qd	0005739	cellular_component	mitochondrion
qd	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
qd	0009055	molecular_function	electron transfer activity
qd	0016020	cellular_component	membrane
qd	0020037	molecular_function	heme binding
qd	0046872	molecular_function	metal ion binding
qD	0005739	cellular_component	mitochondrion
qD	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
qD	0009055	molecular_function	electron transfer activity
qD	0016020	cellular_component	membrane
qD	0020037	molecular_function	heme binding
qD	0046872	molecular_function	metal ion binding
Qd	0005739	cellular_component	mitochondrion
Qd	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Qd	0009055	molecular_function	electron transfer activity
Qd	0016020	cellular_component	membrane
Qd	0020037	molecular_function	heme binding
Qd	0046872	molecular_function	metal ion binding
QD	0005739	cellular_component	mitochondrion
QD	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
QD	0009055	molecular_function	electron transfer activity
QD	0016020	cellular_component	membrane
QD	0020037	molecular_function	heme binding
QD	0046872	molecular_function	metal ion binding
qe	0016020	cellular_component	membrane
qe	0046872	molecular_function	metal ion binding
qe	0051536	molecular_function	iron-sulfur cluster binding
qe	0051537	molecular_function	2 iron, 2 sulfur cluster binding
qE	0016020	cellular_component	membrane
qE	0046872	molecular_function	metal ion binding
qE	0051536	molecular_function	iron-sulfur cluster binding
qE	0051537	molecular_function	2 iron, 2 sulfur cluster binding
Qe	0016020	cellular_component	membrane
Qe	0046872	molecular_function	metal ion binding
Qe	0051536	molecular_function	iron-sulfur cluster binding
Qe	0051537	molecular_function	2 iron, 2 sulfur cluster binding
QE	0016020	cellular_component	membrane
QE	0046872	molecular_function	metal ion binding
QE	0051536	molecular_function	iron-sulfur cluster binding
QE	0051537	molecular_function	2 iron, 2 sulfur cluster binding
qf	0005743	cellular_component	mitochondrial inner membrane
qf	0016020	cellular_component	membrane
qf	0022904	biological_process	respiratory electron transport chain
qf	0046872	molecular_function	metal ion binding
qF	0005743	cellular_component	mitochondrial inner membrane
qF	0016020	cellular_component	membrane
qF	0022904	biological_process	respiratory electron transport chain
qF	0046872	molecular_function	metal ion binding
Qf	0005743	cellular_component	mitochondrial inner membrane
Qf	0016020	cellular_component	membrane
Qf	0022904	biological_process	respiratory electron transport chain
Qf	0046872	molecular_function	metal ion binding
QF	0005743	cellular_component	mitochondrial inner membrane
QF	0016020	cellular_component	membrane
QF	0022904	biological_process	respiratory electron transport chain
QF	0046872	molecular_function	metal ion binding
s1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
s1	0016020	cellular_component	membrane
s1	0016491	molecular_function	oxidoreductase activity
s1	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
s1	0042773	biological_process	ATP synthesis coupled electron transport
s1	0046872	molecular_function	metal ion binding
s1	0051536	molecular_function	iron-sulfur cluster binding
s1	0051537	molecular_function	2 iron, 2 sulfur cluster binding
s1	0051539	molecular_function	4 iron, 4 sulfur cluster binding
s1	1902600	biological_process	proton transmembrane transport
S1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S1	0016020	cellular_component	membrane
S1	0016491	molecular_function	oxidoreductase activity
S1	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S1	0042773	biological_process	ATP synthesis coupled electron transport
S1	0046872	molecular_function	metal ion binding
S1	0051536	molecular_function	iron-sulfur cluster binding
S1	0051537	molecular_function	2 iron, 2 sulfur cluster binding
S1	0051539	molecular_function	4 iron, 4 sulfur cluster binding
S1	1902600	biological_process	proton transmembrane transport
s2	0005739	cellular_component	mitochondrion
s2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
s2	0016491	molecular_function	oxidoreductase activity
s2	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
s2	0048038	molecular_function	quinone binding
s2	0051287	molecular_function	NAD binding
S2	0005739	cellular_component	mitochondrion
S2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S2	0016491	molecular_function	oxidoreductase activity
S2	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S2	0048038	molecular_function	quinone binding
S2	0051287	molecular_function	NAD binding
s3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
s3	0016491	molecular_function	oxidoreductase activity
s3	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
s3	1902600	biological_process	proton transmembrane transport
S3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S3	0016491	molecular_function	oxidoreductase activity
S3	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S3	1902600	biological_process	proton transmembrane transport
s4	0005743	cellular_component	mitochondrial inner membrane
s4	0022900	biological_process	electron transport chain
s4	0022904	biological_process	respiratory electron transport chain
S4	0005743	cellular_component	mitochondrial inner membrane
S4	0022900	biological_process	electron transport chain
S4	0022904	biological_process	respiratory electron transport chain
s6	0005739	cellular_component	mitochondrion
s6	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
s6	0008270	molecular_function	zinc ion binding
s6	0046872	molecular_function	metal ion binding
S6	0005739	cellular_component	mitochondrion
S6	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S6	0008270	molecular_function	zinc ion binding
S6	0046872	molecular_function	metal ion binding
s7	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
s7	0009060	biological_process	aerobic respiration
s7	0015990	biological_process	electron transport coupled proton transport
s7	0016491	molecular_function	oxidoreductase activity
s7	0045271	cellular_component	respiratory chain complex I
s7	0046872	molecular_function	metal ion binding
s7	0048038	molecular_function	quinone binding
s7	0051536	molecular_function	iron-sulfur cluster binding
s7	0051539	molecular_function	4 iron, 4 sulfur cluster binding
S7	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S7	0009060	biological_process	aerobic respiration
S7	0015990	biological_process	electron transport coupled proton transport
S7	0016491	molecular_function	oxidoreductase activity
S7	0045271	cellular_component	respiratory chain complex I
S7	0046872	molecular_function	metal ion binding
S7	0048038	molecular_function	quinone binding
S7	0051536	molecular_function	iron-sulfur cluster binding
S7	0051539	molecular_function	4 iron, 4 sulfur cluster binding
s8	0003954	molecular_function	NADH dehydrogenase activity
s8	0005739	cellular_component	mitochondrion
s8	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
s8	0009060	biological_process	aerobic respiration
s8	0016020	cellular_component	membrane
s8	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
s8	0032981	biological_process	mitochondrial respiratory chain complex I assembly
s8	0046872	molecular_function	metal ion binding
s8	0051536	molecular_function	iron-sulfur cluster binding
s8	0051539	molecular_function	4 iron, 4 sulfur cluster binding
S8	0003954	molecular_function	NADH dehydrogenase activity
S8	0005739	cellular_component	mitochondrion
S8	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S8	0009060	biological_process	aerobic respiration
S8	0016020	cellular_component	membrane
S8	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S8	0032981	biological_process	mitochondrial respiratory chain complex I assembly
S8	0046872	molecular_function	metal ion binding
S8	0051536	molecular_function	iron-sulfur cluster binding
S8	0051539	molecular_function	4 iron, 4 sulfur cluster binding
sa	0000104	molecular_function	succinate dehydrogenase activity
sa	0000166	molecular_function	nucleotide binding
sa	0005743	cellular_component	mitochondrial inner membrane
sa	0006099	biological_process	tricarboxylic acid cycle
sa	0006121	biological_process	mitochondrial electron transport, succinate to ubiquinone
sa	0008177	molecular_function	succinate dehydrogenase (quinone) activity
sa	0009055	molecular_function	electron transfer activity
sa	0016491	molecular_function	oxidoreductase activity
sa	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
sa	0022900	biological_process	electron transport chain
sa	0046872	molecular_function	metal ion binding
sa	0050660	molecular_function	flavin adenine dinucleotide binding
SA	0000104	molecular_function	succinate dehydrogenase activity
SA	0000166	molecular_function	nucleotide binding
SA	0005743	cellular_component	mitochondrial inner membrane
SA	0006099	biological_process	tricarboxylic acid cycle
SA	0006121	biological_process	mitochondrial electron transport, succinate to ubiquinone
SA	0008177	molecular_function	succinate dehydrogenase (quinone) activity
SA	0009055	molecular_function	electron transfer activity
SA	0016491	molecular_function	oxidoreductase activity
SA	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
SA	0022900	biological_process	electron transport chain
SA	0046872	molecular_function	metal ion binding
SA	0050660	molecular_function	flavin adenine dinucleotide binding
sb	0005743	cellular_component	mitochondrial inner membrane
sb	0006099	biological_process	tricarboxylic acid cycle
sb	0008177	molecular_function	succinate dehydrogenase (quinone) activity
sb	0009055	molecular_function	electron transfer activity
sb	0009060	biological_process	aerobic respiration
sb	0016491	molecular_function	oxidoreductase activity
sb	0022904	biological_process	respiratory electron transport chain
sb	0046872	molecular_function	metal ion binding
sb	0051536	molecular_function	iron-sulfur cluster binding
sb	0051537	molecular_function	2 iron, 2 sulfur cluster binding
sb	0051538	molecular_function	3 iron, 4 sulfur cluster binding
sb	0051539	molecular_function	4 iron, 4 sulfur cluster binding
SB	0005743	cellular_component	mitochondrial inner membrane
SB	0006099	biological_process	tricarboxylic acid cycle
SB	0008177	molecular_function	succinate dehydrogenase (quinone) activity
SB	0009055	molecular_function	electron transfer activity
SB	0009060	biological_process	aerobic respiration
SB	0016491	molecular_function	oxidoreductase activity
SB	0022904	biological_process	respiratory electron transport chain
SB	0046872	molecular_function	metal ion binding
SB	0051536	molecular_function	iron-sulfur cluster binding
SB	0051537	molecular_function	2 iron, 2 sulfur cluster binding
SB	0051538	molecular_function	3 iron, 4 sulfur cluster binding
SB	0051539	molecular_function	4 iron, 4 sulfur cluster binding
t1	0000166	molecular_function	nucleotide binding
t1	0005543	molecular_function	phospholipid binding
t1	0006629	biological_process	lipid metabolic process
t1	0008915	molecular_function	lipid-A-disaccharide synthase activity
t1	0009245	biological_process	lipid A biosynthetic process
t1	0016020	cellular_component	membrane
t1	0016740	molecular_function	transferase activity
t1	0016757	molecular_function	glycosyltransferase activity
t1	0046872	molecular_function	metal ion binding
T1	0000166	molecular_function	nucleotide binding
T1	0005543	molecular_function	phospholipid binding
T1	0006629	biological_process	lipid metabolic process
T1	0008915	molecular_function	lipid-A-disaccharide synthase activity
T1	0009245	biological_process	lipid A biosynthetic process
T1	0016020	cellular_component	membrane
T1	0016740	molecular_function	transferase activity
T1	0016757	molecular_function	glycosyltransferase activity
T1	0046872	molecular_function	metal ion binding
t2	0016874	molecular_function	ligase activity
T2	0016874	molecular_function	ligase activity
v1	0000166	molecular_function	nucleotide binding
v1	0005739	cellular_component	mitochondrion
v1	0005743	cellular_component	mitochondrial inner membrane
v1	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
v1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
v1	0010181	molecular_function	FMN binding
v1	0022904	biological_process	respiratory electron transport chain
v1	0046872	molecular_function	metal ion binding
v1	0051287	molecular_function	NAD binding
v1	0051536	molecular_function	iron-sulfur cluster binding
v1	0051539	molecular_function	4 iron, 4 sulfur cluster binding
v1	1902600	biological_process	proton transmembrane transport
V1	0000166	molecular_function	nucleotide binding
V1	0005739	cellular_component	mitochondrion
V1	0005743	cellular_component	mitochondrial inner membrane
V1	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
V1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
V1	0010181	molecular_function	FMN binding
V1	0022904	biological_process	respiratory electron transport chain
V1	0046872	molecular_function	metal ion binding
V1	0051287	molecular_function	NAD binding
V1	0051536	molecular_function	iron-sulfur cluster binding
V1	0051539	molecular_function	4 iron, 4 sulfur cluster binding
V1	1902600	biological_process	proton transmembrane transport
v2	0003954	molecular_function	NADH dehydrogenase activity
v2	0005743	cellular_component	mitochondrial inner membrane
v2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
v2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
v2	0016491	molecular_function	oxidoreductase activity
v2	0046872	molecular_function	metal ion binding
v2	0051536	molecular_function	iron-sulfur cluster binding
v2	0051537	molecular_function	2 iron, 2 sulfur cluster binding
v2	0098796	cellular_component	membrane protein complex
v2	1902494	cellular_component	catalytic complex
v2	1902600	biological_process	proton transmembrane transport
V2	0003954	molecular_function	NADH dehydrogenase activity
V2	0005743	cellular_component	mitochondrial inner membrane
V2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
V2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
V2	0016491	molecular_function	oxidoreductase activity
V2	0046872	molecular_function	metal ion binding
V2	0051536	molecular_function	iron-sulfur cluster binding
V2	0051537	molecular_function	2 iron, 2 sulfur cluster binding
V2	0098796	cellular_component	membrane protein complex
V2	1902494	cellular_component	catalytic complex
V2	1902600	biological_process	proton transmembrane transport
vb	0005740	cellular_component	mitochondrial envelope
vb	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
vb	0045277	cellular_component	respiratory chain complex IV
vb	0046872	molecular_function	metal ion binding
VB	0005740	cellular_component	mitochondrial envelope
VB	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
VB	0045277	cellular_component	respiratory chain complex IV
VB	0046872	molecular_function	metal ion binding
y	0000166	molecular_function	nucleotide binding
y	0005524	molecular_function	ATP binding
Y	0000166	molecular_function	nucleotide binding
Y	0005524	molecular_function	ATP binding
y5	0046872	molecular_function	metal ion binding
Y5	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. KLGLDSLDQTALLASI

Chain	Residue	Details
ab	LYS90-ILE105

---

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CsCgiSqsGPwC

Chain	Residue	Details
fs	CYS99-CYS110

---

site_id	PS00077
Number of Residues	55
Details	COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WFFGHPeVyvliiptfgfinmivphnntrrvaskhhmiwaiyvmaymgylvwg..HH

Chain	Residue	Details
81	TRP387-HIS441

---

site_id	PS00197
Number of Residues	9
Details	2FE2S_FER_1 2Fe-2S ferredoxin-type iron-sulfur binding region signature. CREGICGSC

Chain	Residue	Details
sb	CYS122-CYS130

---

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CvLCAaCStSCP

Chain	Residue	Details
sb	CYS215-PRO226
S8	CYS136-PRO147
S8	CYS175-PRO186

---

site_id	PS00213
Number of Residues	13
Details	LIPOCALIN Lipocalin signature. NWEy.QYDGQWWSM

Chain	Residue	Details
b4	ASN81-MET93

---

site_id	PS00504
Number of Residues	10
Details	FRD_SDH_FAD_BINDING Fumarate reductase / succinate dehydrogenase FAD-binding site. RSHTvaAqGG

Chain	Residue	Details
sa	ARG84-GLY93

---

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGsEKLiEdR

Chain	Residue	Details
S2	LEU62-ARG73

---

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREtsEMYginykwKidtRkLL

Chain	Residue	Details
S3	GLU136-LEU157

---

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC

Chain	Residue	Details
S1	PRO62-CYS79

---

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ

Chain	Residue	Details
S1	CYS129-GLN141

---

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIhCtRCVrF

Chain	Residue	Details
S1	ARG176-PHE186

---

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
V1	GLU378-GLY389

---

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GRLQyIaDALKLFiKG

Chain	Residue	Details
N1	GLY63-GLY78

---

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLAEAEseLVt.G

Chain	Residue	Details
N1	PRO218-GLY231

---

site_id	PS00848
Number of Residues	23
Details	COX5B_1 Cytochrome c oxidase subunit Vb, zinc binding region signature. LLFfllregslqrCmgCGqvFKL

Chain	Residue	Details
vb	LEU175-LEU197

---